2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Hypoxia-Ischemia, Brain in 9 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
Hypoxia-Ischemia, Brain: A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Baicalin has been shown to provide the neuroprotective effect by alleviating cerebral ischemia injury." | 1.42 | Baicalin inhibiting cerebral ischemia/hypoxia-induced neuronal apoptosis via MRTF-A-mediated transactivity. ( Cao, XL; Dong, W; Hu, XM; Min, ZL; Wang, F; Wang, J; Wu, FJ; Xiao, W; Xing, H; Xu, SQ; Ying, TZ; Zhang, Y; Zheng, WX, 2015) |
| "Wortmannin pretreatment could aggravate the histological injury and decrease axonal density after HI." | 1.39 | [The regulation of Akt signaling on axonal density after hypoxic-ischemic brain injury in neonatal rat]. ( Chen, HJ; Luo, BR; Mu, DZ; Qu, Y; Xiong, T, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 8 (88.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Luo, Z | 1 |
| Zhang, M | 1 |
| Niu, X | 1 |
| Tang, J | 1 |
| Xiong, T | 2 |
| Chen, HJ | 2 |
| Qu, Y | 2 |
| Luo, BR | 1 |
| Mu, DZ | 3 |
| Xue, X | 1 |
| You, Y | 1 |
| Tao, J | 1 |
| Ye, X | 1 |
| Huang, J | 1 |
| Yang, S | 1 |
| Lin, Z | 1 |
| Hong, Z | 1 |
| Peng, J | 1 |
| Chen, L | 1 |
| Zheng, WX | 1 |
| Cao, XL | 1 |
| Wang, F | 2 |
| Wang, J | 1 |
| Ying, TZ | 1 |
| Xiao, W | 1 |
| Zhang, Y | 1 |
| Xing, H | 1 |
| Dong, W | 1 |
| Xu, SQ | 1 |
| Min, ZL | 1 |
| Wu, FJ | 1 |
| Hu, XM | 1 |
| Zhang, DS | 1 |
| Bai, XH | 1 |
| Yao, YJ | 1 |
| Chen, J | 1 |
| Guo, SY | 1 |
| Yang, GP | 1 |
| Jiang, DJ | 1 |
| Song, T | 1 |
| Tan, XH | 1 |
| Sun, ZQ | 1 |
| Lee, HT | 1 |
| Chang, YC | 1 |
| Tu, YF | 1 |
| Huang, CC | 1 |
| Ha, YM | 1 |
| Kim, MY | 1 |
| Park, MK | 1 |
| Lee, YS | 1 |
| Kim, YM | 1 |
| Kim, HJ | 1 |
| Lee, JH | 1 |
| Chang, KC | 1 |
9 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Hypoxia-Ischemia, Brain
| Article | Year |
|---|---|
Inhibition of the PI3K/Akt signaling pathway impedes the restoration of neurological function following hypoxic-ischemic brain damage in a neonatal rabbit model.
Topics: Animals; Animals, Newborn; Apoptosis; Apoptosis Regulatory Proteins; Brain; Caspase 3; Chromones; Di | 2019 |
[The regulation of Akt signaling on axonal density after hypoxic-ischemic brain injury in neonatal rat].
Topics: Androstadienes; Animals; Animals, Newborn; Axons; Chromones; Enzyme Inhibitors; Female; Glycogen Syn | 2013 |
Electro-acupuncture at points of Zusanli and Quchi exerts anti-apoptotic effect through the modulation of PI3K/Akt signaling pathway.
Topics: Acupuncture Points; Animals; Apoptosis; Cerebral Infarction; Chromones; Electroacupuncture; Hypoxia- | 2014 |
[The Involvement of CRMP-2 on Axonal and Dendrictic Injury after Hypoxic-Ischemic Brain Injury in Neonatal Rat].
Topics: Animals; Animals, Newborn; Axons; Blotting, Western; Chromones; Dendrites; Hypoxia; Hypoxia-Ischemia | 2015 |
Baicalin inhibiting cerebral ischemia/hypoxia-induced neuronal apoptosis via MRTF-A-mediated transactivity.
Topics: Animals; Apoptosis; Cerebral Cortex; Chromones; Dose-Response Relationship, Drug; Flavonoids; Hypoxi | 2015 |
[Umbilical Cord-derived Mesenchymal Stem Cells Grafts for Neonatal Rats Model of HIBD: the Mechanism of PI3K/Akt Signaling Pathway].
Topics: Animals; Animals, Newborn; Brain; Caspase 3; Chromones; Hypoxia-Ischemia, Brain; Mesenchymal Stem Ce | 2015 |
Protection of capsaicin against hypoxia-reoxygenation-induced apoptosis of rat hippocampal neurons.
Topics: Animals; Apoptosis; Blotting, Western; Capsaicin; Caspase 3; Caspase Inhibitors; Cells, Cultured; Ch | 2008 |
CREB activation mediates VEGF-A's protection of neurons and cerebral vascular endothelial cells.
Topics: Animals; Animals, Newborn; Brain Injuries; Cell Survival; Cells, Cultured; Chromones; CREB-Binding P | 2010 |
Higenamine reduces HMGB1 during hypoxia-induced brain injury by induction of heme oxygenase-1 through PI3K/Akt/Nrf-2 signal pathways.
Topics: Alkaloids; Animals; Apoptosis; Apoptosis Regulatory Proteins; Cell Hypoxia; Cell Survival; Cells, Cu | 2012 |