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2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Hyperplasia

2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Hyperplasia in 6 studies

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source

Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.

Research Excerpts

ExcerptRelevanceReference
"Our results show that leptin induced glomerular mesangial cell hypertrophy via PI 3-kinase and ERK1/2, and that hyperplasia and apoptosis were not altered by leptin."7.73Leptin induces rat glomerular mesangial cell hypertrophy, but does not regulate hyperplasia or apoptosis. ( Lee, MP; Orlov, D; Sweeney, G, 2005)
"Our results show that leptin induced glomerular mesangial cell hypertrophy via PI 3-kinase and ERK1/2, and that hyperplasia and apoptosis were not altered by leptin."3.73Leptin induces rat glomerular mesangial cell hypertrophy, but does not regulate hyperplasia or apoptosis. ( Lee, MP; Orlov, D; Sweeney, G, 2005)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (83.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rho, O1
Kiguchi, K1
Jiang, G1
DiGiovanni, J1
Zahradka, P1
Harding, G1
Litchie, B1
Thomas, S1
Werner, JP1
Wilson, DP1
Yurkova, N1
Lee, MP1
Orlov, D1
Sweeney, G1
Wang, Y1
Bai, Y1
Qin, L1
Zhang, P1
Yi, T1
Teesdale, SA1
Zhao, L1
Pober, JS1
Tellides, G1
Rose, ML1
Willis, AI1
Fuse, S1
Wang, XJ1
Chen, E1
Tuszynski, GP1
Sumpio, BE1
Gahtan, V1

Other Studies

6 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Hyperplasia

ArticleYear
Impact of mTORC1 inhibition on keratinocyte proliferation during skin tumor promotion in wild-type and BK5.AktWT mice.
    Molecular carcinogenesis, 2014, Volume: 53, Issue:11

    Topics: Animals; Antibiotics, Antineoplastic; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cell

2014
Activation of MMP-2 in response to vascular injury is mediated by phosphatidylinositol 3-kinase-dependent expression of MT1-MMP.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:6

    Topics: Androstadienes; Angioplasty, Balloon, Coronary; Animals; Cell Movement; Chromones; Coronary Vessels;

2004
Leptin induces rat glomerular mesangial cell hypertrophy, but does not regulate hyperplasia or apoptosis.
    International journal of obesity (2005), 2005, Volume: 29, Issue:12

    Topics: Animals; Apoptosis; Cell Size; Cells, Cultured; Chromones; Extracellular Signal-Regulated MAP Kinase

2005
Interferon-gamma induces human vascular smooth muscle cell proliferation and intimal expansion by phosphatidylinositol 3-kinase dependent mammalian target of rapamycin raptor complex 1 activation.
    Circulation research, 2007, Sep-14, Volume: 101, Issue:6

    Topics: Adaptor Proteins, Signal Transducing; Adenoviridae; Animals; Aorta; Cell Proliferation; Cells, Cultu

2007
Interferon-gamma and intimal hyperplasia.
    Circulation research, 2007, Sep-14, Volume: 101, Issue:6

    Topics: Adaptor Proteins, Signal Transducing; Adenoviridae; Animals; Cell Proliferation; Chromones; Coronary

2007
Inhibition of phosphatidylinositol 3-kinase and protein kinase C attenuates extracellular matrix protein-induced vascular smooth muscle cell chemotaxis.
    Journal of vascular surgery, 2000, Volume: 31, Issue:6

    Topics: Animals; Cattle; Cell Count; Cell Division; Cells, Cultured; Chemotaxis; Chromones; Enzyme Inhibitor

2000