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2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Hemorrhage, Subarachnoid

2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Hemorrhage, Subarachnoid in 10 studies

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source

Research Excerpts

ExcerptRelevanceReference
"Hydrogen can inhibit neuronal apoptosis and attenuate EBI following SAH."5.40Neuroprotective effect of hydrogen-rich saline against neurologic damage and apoptosis in early brain injury following subarachnoid hemorrhage: possible role of the Akt/GSK3β signaling pathway. ( Chen, S; Hong, Y; McBride, DW; Shao, A; Sun, X; Wang, J; Wu, H; Wu, Q; Zhang, J, 2014)
"Zileuton and LY294002 were used to inhibit expression of 5-LOX and Akt, respectively."1.625-Lipoxygenase inhibition reduces inflammation and neuronal apoptosis via AKT signaling after subarachnoid hemorrhage in rats. ( Chen, H; Deng, Y; Guo, Z; He, Z; Liang, Y; Liu, L; Sun, X; Zhang, P; Zhang, Z, 2021)
"However, its effectiveness against subarachnoid hemorrhage (SAH) is not well known."1.43Matrine alleviates early brain injury after experimental subarachnoid hemorrhage in rats: possible involvement of PI3K/Akt-mediated NF-κB inhibition and Keap1/Nrf2-dependent HO-1 inductionn. ( Hou, P; Liu, X; Liu, Z; Ma, K; Sun, B; Wang, Z; Yuan, S; Zhang, R; Zhang, X, 2016)
"Hydrogen can inhibit neuronal apoptosis and attenuate EBI following SAH."1.40Neuroprotective effect of hydrogen-rich saline against neurologic damage and apoptosis in early brain injury following subarachnoid hemorrhage: possible role of the Akt/GSK3β signaling pathway. ( Chen, S; Hong, Y; McBride, DW; Shao, A; Sun, X; Wang, J; Wu, H; Wu, Q; Zhang, J, 2014)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's6 (60.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Yan, C1
Yu, H1
Liu, Y1
Wu, P2
Wang, C1
Zhao, H1
Yang, K1
Shao, Q1
Zhong, Y1
Zhao, W1
Li, J1
Liu, N1
Di, J1
Li, C1
Bao, L1
Gao, C1
Liu, L1
Zhang, P1
Zhang, Z1
Liang, Y1
Chen, H1
He, Z2
Sun, X3
Guo, Z2
Deng, Y1
Zhang, H1
Jiang, L1
Zhong, J1
Wu, J1
He, J1
Liu, H1
Wu, H2
Cheng, C1
Xie, Z3
Enkhjargal, B2
Wu, L1
Zhou, K1
Sun, C2
Hu, X1
Gospodarev, V1
Tang, J2
You, C1
Zhang, JH3
Zhu, Q1
Huang, L1
Zhang, T1
Mo, J1
Hong, Y1
Shao, A1
Wang, J1
Chen, S1
McBride, DW1
Wu, Q1
Zhang, J1
Hao, XK1
Wu, W1
Wang, CX1
Xie, GB1
Li, T1
Wu, HM1
Huang, LT1
Zhou, ML1
Hang, CH1
Shi, JX1
Liu, X1
Zhang, X1
Ma, K1
Zhang, R1
Hou, P1
Sun, B1
Yuan, S1
Wang, Z1
Liu, Z1
Endo, H1
Nito, C1
Kamada, H1
Yu, F1
Chan, PH1
Kimura, H1
Sasaki, K1
Meguro, T1

Other Studies

10 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Hemorrhage, Subarachnoid

ArticleYear
c-Abl Tyrosine Kinase-Mediated Neuronal Apoptosis in Subarachnoid Hemorrhage by Modulating the LRP-1-Dependent Akt/GSK3β Survival Pathway.
    Journal of molecular neuroscience : MN, 2021, Volume: 71, Issue:12

    Topics: Animals; Apoptosis; Caspase 3; Chromones; Glycogen Synthase Kinase 3 beta; Low Density Lipoprotein R

2021
5-Lipoxygenase inhibition reduces inflammation and neuronal apoptosis via AKT signaling after subarachnoid hemorrhage in rats.
    Aging, 2021, 04-20, Volume: 13, Issue:8

    Topics: Administration, Oral; Animals; Apoptosis; Arachidonate 5-Lipoxygenase; Brain Injuries; Chromones; Di

2021
PPARβ/δ, a Novel Regulator for Vascular Smooth Muscle Cells Phenotypic Modulation and Vascular Remodeling after Subarachnoid Hemorrhage in Rats.
    Scientific reports, 2017, 03-22, Volume: 7

    Topics: Animals; Chromones; Male; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype;

2017
Exendin-4 attenuates neuronal death via GLP-1R/PI3K/Akt pathway in early brain injury after subarachnoid hemorrhage in rats.
    Neuropharmacology, 2018, Volume: 128

    Topics: Animals; Apoptosis; Brain Injuries; Calcium-Binding Proteins; Chromones; Disease Models, Animal; Enz

2018
Aggf1 attenuates neuroinflammation and BBB disruption via PI3K/Akt/NF-κB pathway after subarachnoid hemorrhage in rats.
    Journal of neuroinflammation, 2018, Jun-09, Volume: 15, Issue:1

    Topics: Angiogenic Proteins; Animals; Blood-Brain Barrier; Brain Edema; Capillary Permeability; Chromones; D

2018
Neuroprotective effect of hydrogen-rich saline against neurologic damage and apoptosis in early brain injury following subarachnoid hemorrhage: possible role of the Akt/GSK3β signaling pathway.
    PloS one, 2014, Volume: 9, Issue:4

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cerebral Cortex; Chromones; Glycogen Synthase Kin

2014
Ghrelin alleviates early brain injury after subarachnoid hemorrhage via the PI3K/Akt signaling pathway.
    Brain research, 2014, Oct-31, Volume: 1587

    Topics: Animals; Apoptosis; Brain Damage, Chronic; Brain Edema; Caspase 3; Chromones; Enzyme Induction; Ghre

2014
Matrine alleviates early brain injury after experimental subarachnoid hemorrhage in rats: possible involvement of PI3K/Akt-mediated NF-κB inhibition and Keap1/Nrf2-dependent HO-1 inductionn.
    Cellular and molecular biology (Noisy-le-Grand, France), 2016, Sep-30, Volume: 62, Issue:11

    Topics: Alkaloids; Animals; Blood-Brain Barrier; Brain Injuries; Chromones; Disease Models, Animal; Heme Oxy

2016
Akt/GSK3beta survival signaling is involved in acute brain injury after subarachnoid hemorrhage in rats.
    Stroke, 2006, Volume: 37, Issue:8

    Topics: Animals; Apoptosis; Brain; Cell Survival; Chromones; DNA Fragmentation; Glycogen Synthase Kinase 3;

2006
Phosphatidylinositol 3-kinase inhibitor failed to reduce cerebral vasospasm in dog model of experimental subarachnoid hemorrhage.
    Stroke, 2002, Volume: 33, Issue:2

    Topics: Androstadienes; Animals; Basilar Artery; Blotting, Western; Brain; Cerebral Angiography; Chromones;

2002