2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Glaucoma in 2 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In summary, we conclude that Acteoside inhibits autophagy-induced apoptosis in RGCs through the OPTN and PI3K/AKT/mTOR pathway, and glaucoma patients may benefit from Acteoside treatment alone or in combination with other autophagy inhibitors." | 7.91 | Acteoside inhibits autophagic apoptosis of retinal ganglion cells to rescue glaucoma-induced optic atrophy. ( Chen, Q; He, Z; Li, Y; Xi, X; Zeng, Y; Zhao, J, 2019) |
| "In summary, we conclude that Acteoside inhibits autophagy-induced apoptosis in RGCs through the OPTN and PI3K/AKT/mTOR pathway, and glaucoma patients may benefit from Acteoside treatment alone or in combination with other autophagy inhibitors." | 3.91 | Acteoside inhibits autophagic apoptosis of retinal ganglion cells to rescue glaucoma-induced optic atrophy. ( Chen, Q; He, Z; Li, Y; Xi, X; Zeng, Y; Zhao, J, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, ST | 1 |
| Zhong, SM | 1 |
| Li, XY | 1 |
| Gao, F | 1 |
| Li, F | 1 |
| Zhang, ML | 1 |
| Zhu, K | 1 |
| Sun, XH | 1 |
| Wang, X | 1 |
| Miao, Y | 1 |
| Yang, XL | 1 |
| Wang, Z | 1 |
| Chen, Q | 1 |
| Xi, X | 1 |
| Zeng, Y | 1 |
| He, Z | 1 |
| Zhao, J | 1 |
| Li, Y | 1 |
2 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Glaucoma
| Article | Year |
|---|---|
EphrinB/EphB forward signaling in Müller cells causes apoptosis of retinal ganglion cells by increasing tumor necrosis factor alpha production in rat experimental glaucomatous model.
Topics: Animals; Animals, Newborn; Antioxidants; Apoptosis; Cells, Cultured; Chromones; Disease Models, Anim | 2018 |
Acteoside inhibits autophagic apoptosis of retinal ganglion cells to rescue glaucoma-induced optic atrophy.
Topics: Animals; Apoptosis; Autophagy; Cell Line; Chromones; Glaucoma; Glucosides; Humans; Mice; Microscopy, | 2019 |