2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Gastrointestinal Stromal Tumors in 2 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
Gastrointestinal Stromal Tumors: All tumors in the GASTROINTESTINAL TRACT arising from mesenchymal cells (MESODERM) except those of smooth muscle cells (LEIOMYOMA) or Schwann cells (SCHWANNOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Most gastrointestinal stromal tumors (GISTs) possess a gain-of-function mutation in c-KIT." | 1.33 | Therapeutic effect of imatinib in gastrointestinal stromal tumors: AKT signaling dependent and independent mechanisms. ( Eisenberg, B; Godwin, AK; Skorobogatko, YV; Taguchi, T; Tarn, C; von Mehren, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tarn, C | 1 |
| Skorobogatko, YV | 1 |
| Taguchi, T | 2 |
| Eisenberg, B | 1 |
| von Mehren, M | 1 |
| Godwin, AK | 1 |
| Ikezoe, T | 1 |
| Yang, Y | 1 |
| Nishioka, C | 1 |
| Bandobashi, K | 1 |
| Nakatani, H | 1 |
| Koeffler, HP | 1 |
| Taguchi, H | 1 |
2 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Gastrointestinal Stromal Tumors
| Article | Year |
|---|---|
Therapeutic effect of imatinib in gastrointestinal stromal tumors: AKT signaling dependent and independent mechanisms.
Topics: Apoptosis; Benzamides; Chromones; Gastrointestinal Stromal Tumors; Glucose; Glucose Transporter Type | 2006 |
Effect of SU11248 on gastrointestinal stromal tumor-T1 cells: enhancement of growth inhibition via inhibition of 3-kinase/Akt/mammalian target of rapamycin signaling.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Line, Tumor; Cell Pro | 2006 |