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2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Experimental Neoplasms

2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Experimental Neoplasms in 10 studies

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source

Research Excerpts

ExcerptRelevanceReference
"with the ovarian cancer cell line OVCAR-3."1.31In vivo and in vitro ovarian carcinoma growth inhibition by a phosphatidylinositol 3-kinase inhibitor (LY294002). ( Gray, J; Hu, L; Jaffe, RB; Mills, GB; Zaloudek, C, 2000)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (60.00)29.6817
2010's4 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yin, Y1
Sha, S1
Wu, X1
Wang, SF1
Qiao, F1
Song, ZC1
Zhu, HL1
Mango, RL1
Wu, QP1
West, M1
McCook, EC1
Serody, JS1
van Deventer, HW1
Lalaoui, N1
Morlé, A1
Mérino, D1
Jacquemin, G1
Iessi, E1
Morizot, A1
Shirley, S1
Robert, B1
Solary, E1
Garrido, C1
Micheau, O1
Collak, FK1
Yagiz, K1
Luthringer, DJ1
Erkaya, B1
Cinar, B1
Samuels, Y1
Diaz, LA1
Schmidt-Kittler, O1
Cummins, JM1
Delong, L1
Cheong, I1
Rago, C1
Huso, DL1
Lengauer, C1
Kinzler, KW1
Vogelstein, B1
Velculescu, VE1
Coffey, JC1
Wang, JH1
Bouchier-Hayes, D1
Cotter, TG1
Redmond, HP1
Gowan, SM1
Hardcastle, A1
Hallsworth, AE1
Valenti, MR1
Hunter, LJ1
de Haven Brandon, AK1
Garrett, MD1
Raynaud, F1
Workman, P1
Aherne, W1
Eccles, SA1
Lu, TL1
Chang, JL1
Liang, CC1
You, LR1
Chen, CM1
Rak, J1
Mitsuhashi, Y1
Sheehan, C1
Tamir, A1
Viloria-Petit, A1
Filmus, J1
Mansour, SJ1
Ahn, NG1
Kerbel, RS1
Hu, L1
Zaloudek, C1
Mills, GB1
Gray, J1
Jaffe, RB1

Other Studies

10 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Experimental Neoplasms

ArticleYear
Development of novel chromeno[4,3-c]pyrazol-4(2H)-one derivates bearing sulfonylpiperazine as antitumor inhibitors targeting PI3Kα.
    European journal of medicinal chemistry, 2019, Nov-15, Volume: 182

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Chromones; Dose-Response Relationship

2019
C-C chemokine receptor 5 on pulmonary mesenchymal cells promotes experimental metastasis via the induction of erythroid differentiation regulator 1.
    Molecular cancer research : MCR, 2014, Volume: 12, Issue:2

    Topics: Animals; CCR5 Receptor Antagonists; Cell Line, Tumor; Chromones; Coculture Techniques; Female; Gene

2014
TRAIL-R4 promotes tumor growth and resistance to apoptosis in cervical carcinoma HeLa cells through AKT.
    PloS one, 2011, Volume: 6, Issue:5

    Topics: Animals; Apoptosis; Blotting, Western; Cell Membrane; Cell Proliferation; Chromones; Enzyme Inhibito

2011
Threonine-120 phosphorylation regulated by phosphoinositide-3-kinase/Akt and mammalian target of rapamycin pathway signaling limits the antitumor activity of mammalian sterile 20-like kinase 1.
    The Journal of biological chemistry, 2012, Jul-06, Volume: 287, Issue:28

    Topics: Animals; Blotting, Western; Cell Line, Tumor; Cell Nucleus; Chromones; HEK293 Cells; HeLa Cells; Hum

2012
Mutant PIK3CA promotes cell growth and invasion of human cancer cells.
    Cancer cell, 2005, Volume: 7, Issue:6

    Topics: Amino Acid Substitution; Animals; Apoptosis; Apoptosis Regulatory Proteins; Base Sequence; Cell Line

2005
The targeting of phosphoinositide-3 kinase attenuates pulmonary metastatic tumor growth following laparotomy.
    Annals of surgery, 2006, Volume: 243, Issue:2

    Topics: Adenocarcinoma; Animals; Apoptosis; Blotting, Western; Cell Division; Chromones; Enzyme Inhibitors;

2006
Application of meso scale technology for the measurement of phosphoproteins in human tumor xenografts.
    Assay and drug development technologies, 2007, Volume: 5, Issue:3

    Topics: Animals; Cell Line, Tumor; Chromones; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3

2007
Tumor spectrum, tumor latency and tumor incidence of the Pten-deficient mice.
    PloS one, 2007, Nov-28, Volume: 2, Issue:11

    Topics: Animals; Chromones; Disease-Free Survival; Female; Incidence; Integrases; Male; Mice; Mice, Inbred S

2007
Oncogenes and tumor angiogenesis: differential modes of vascular endothelial growth factor up-regulation in ras-transformed epithelial cells and fibroblasts.
    Cancer research, 2000, Jan-15, Volume: 60, Issue:2

    Topics: 3T3 Cells; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Chromones; Endothelia

2000
In vivo and in vitro ovarian carcinoma growth inhibition by a phosphatidylinositol 3-kinase inhibitor (LY294002).
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:3

    Topics: Animals; Apoptosis; Ascites; Cell Division; Chromones; Enzyme Inhibitors; Female; Humans; Mice; Mice

2000