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2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Di Guglielmo Disease

2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Di Guglielmo Disease in 7 studies

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source

Research Excerpts

ExcerptRelevanceReference
"Erythroid differentiation of human erythroleukemia cell line K562 induced by erythropoietin is a complex process that involves modifications at nuclear level, including nuclear translocation of phosphatidyl-inositol 3-kinase."1.35Nuclear translocation of active AKT is required for erythroid differentiation in erythropoietin treated K562 erythroleukemia cells. ( Buontempo, F; Capitani, S; Etro, D; Missiroli, S; Neri, LM; Ye, K, 2009)
"We found that in a human erythroleukemia cell line, as well as in rabbit platelets, PI 3-kinase and PKCdelta associate in a specific manner that is modulated by cell activation."1.29Protein kinase C delta specifically associates with phosphatidylinositol 3-kinase following cytokine stimulation. ( Duronio, V; Ettinger, SL; Lauener, RW, 1996)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's6 (85.71)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Missiroli, S1
Etro, D1
Buontempo, F1
Ye, K1
Capitani, S1
Neri, LM1
Fukumoto, T1
Kubota, Y1
Kitanaka, A1
Yamaoka, G1
Ohara-Waki, F1
Imataki, O1
Ohnishi, H1
Ishida, T1
Tanaka, T1
Lambert, E1
Boudot, C1
Kadri, Z1
Soula-Rothhut, M1
Sowa, ML1
Mayeux, P1
Hornebeck, W1
Haye, B1
Petitfrere, E1
Ettinger, SL1
Lauener, RW1
Duronio, V1
Bavelloni, A1
Faenza, I1
Aluigi, M1
Ferri, A1
Toker, A1
Maraldi, NM1
Marmiroli, S1
Cataldi, A2
Di Pietro, R2
Centurione, L1
Grilli, A1
Cutroneo, G1
Miscia, S1
Zauli, G1
Castorina, S1
Rana, R1

Other Studies

7 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Di Guglielmo Disease

ArticleYear
Nuclear translocation of active AKT is required for erythroid differentiation in erythropoietin treated K562 erythroleukemia cells.
    The international journal of biochemistry & cell biology, 2009, Volume: 41, Issue:3

    Topics: Active Transport, Cell Nucleus; Androstadienes; Cell Differentiation; Cell Lineage; Cell Nucleus; Ch

2009
Gab1 transduces PI3K-mediated erythropoietin signals to the Erk pathway and regulates erythropoietin-dependent proliferation and survival of erythroid cells.
    Cellular signalling, 2009, Volume: 21, Issue:12

    Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Cell Line, Tumor; Cell Proliferation; Chromones; En

2009
Tissue inhibitor of metalloproteinases-1 signalling pathway leading to erythroid cell survival.
    The Biochemical journal, 2003, Jun-15, Volume: 372, Issue:Pt 3

    Topics: Animals; Cell Line; Cell Survival; Chromones; Enzyme Inhibitors; Erythrocytes; Humans; Janus Kinase

2003
Protein kinase C delta specifically associates with phosphatidylinositol 3-kinase following cytokine stimulation.
    The Journal of biological chemistry, 1996, Jun-14, Volume: 271, Issue:24

    Topics: Androstadienes; Animals; Blood Platelets; Cell Line; Chromones; Cytokines; Enzyme Inhibitors; Granul

1996
Inhibition of phosphoinositide 3-kinase impairs pre-commitment cell cycle traverse and prevents differentiation in erythroleukaemia cells.
    Cell death and differentiation, 2000, Volume: 7, Issue:1

    Topics: Androstadienes; Cell Cycle; Cell Differentiation; Chromones; Cyclin D3; Cyclins; Enzyme Inhibitors;

2000
Phosphatidylinositol-3-kinase activation and atypical protein kinase C zeta phosphorylation characterize the DMSO signalling in erythroleukemia cells.
    Cellular signalling, 2000, Volume: 12, Issue:9-10

    Topics: Androstadienes; Animals; Chromones; Dimethyl Sulfoxide; Enzyme Activation; Enzyme Inhibitors; Hemato

2000
Involvement of the pathway phosphatidylinositol-3-kinase/AKT-1 in the establishment of the survival response to ionizing radiation.
    Cellular signalling, 2001, Volume: 13, Issue:5

    Topics: Androstadienes; Cell Survival; Chromones; DNA Repair; Enzyme Activation; Enzyme Inhibitors; Humans;

2001