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2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Cell Transformation, Viral

2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Cell Transformation, Viral in 8 studies

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source

Cell Transformation, Viral: An inheritable change in cells manifested by changes in cell division and growth and alterations in cell surface properties. It is induced by infection with a transforming virus.

Research Excerpts

ExcerptRelevanceReference
"We showed earlier that cellular retinol-binding protein (CRBP) expression is downregulated in a subset of human breast cancers."3.71CRBP suppresses breast cancer cell survival and anchorage-independent growth. ( Kuppumbatti, YS; Mira-y-Lopez, R; Nakajo, S; Nakaya, K; Rexer, B, 2001)
"Gastric cancer is the most common cancer in Japan and infection with Epstein-Barr virus (EBV) is responsible for about 10% of gastric cancers worldwide."1.35Epstein-Barr virus upregulates phosphorylated heat shock protein 27 kDa in carcinoma cells using the phosphoinositide 3-kinase/Akt pathway. ( Fujimoto, M; Fukagawa, Y; Imai, S; Iwakiri, D; Kuramitsu, Y; Nakamura, K; Nishikawa, J; Okamoto, T; Okita, K; Sakaida, I; Satake, M; Takada, K, 2008)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fukagawa, Y1
Nishikawa, J1
Kuramitsu, Y1
Iwakiri, D1
Takada, K1
Imai, S1
Satake, M1
Okamoto, T1
Fujimoto, M1
Okita, K1
Nakamura, K1
Sakaida, I1
Dawson, CW1
Tramountanis, G1
Eliopoulos, AG1
Young, LS1
Maeda, N1
Inoshima, Y1
Fruman, DA1
Brachmann, SM1
Fan, H1
Agazie, YM1
Movilla, N1
Ischenko, I2
Hayman, MJ1
Jeong, SJ1
Pise-Masison, CA1
Radonovich, MF1
Park, HU1
Brady, JN1
Fukuda, M1
Longnecker, R1
Kuppumbatti, YS1
Rexer, B1
Nakajo, S1
Nakaya, K1
Mira-y-Lopez, R1
Agazie, Y1
Hayman, M1

Other Studies

8 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Cell Transformation, Viral

ArticleYear
Epstein-Barr virus upregulates phosphorylated heat shock protein 27 kDa in carcinoma cells using the phosphoinositide 3-kinase/Akt pathway.
    Electrophoresis, 2008, Volume: 29, Issue:15

    Topics: Adenocarcinoma; Amino Acid Sequence; Androstadienes; Arsenites; Cell Line, Tumor; Cell Transformatio

2008
Epstein-Barr virus latent membrane protein 1 (LMP1) activates the phosphatidylinositol 3-kinase/Akt pathway to promote cell survival and induce actin filament remodeling.
    The Journal of biological chemistry, 2003, Feb-07, Volume: 278, Issue:6

    Topics: Actins; Animals; Cell Line; Cell Survival; Cell Transformation, Viral; Chromones; Enzyme Activation;

2003
Transformation of mouse fibroblasts by Jaagsiekte sheep retrovirus envelope does not require phosphatidylinositol 3-kinase.
    Journal of virology, 2003, Volume: 77, Issue:18

    Topics: 3T3 Cells; Amino Acid Motifs; Animals; Cell Transformation, Viral; Chromones; Jaagsiekte sheep retro

2003
The phosphotyrosine phosphatase SHP2 is a critical mediator of transformation induced by the oncogenic fibroblast growth factor receptor 3.
    Oncogene, 2003, Oct-09, Volume: 22, Issue:44

    Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Animals; Calcium-Calmodulin-Dependent Protein Kinas

2003
Activated AKT regulates NF-kappaB activation, p53 inhibition and cell survival in HTLV-1-transformed cells.
    Oncogene, 2005, Oct-06, Volume: 24, Issue:44

    Topics: bcl-X Protein; Cell Line, Transformed; Cell Survival; Cell Transformation, Viral; Chromones; Enzyme

2005
Epstein-Barr virus latent membrane protein 2A mediates transformation through constitutive activation of the Ras/PI3-K/Akt Pathway.
    Journal of virology, 2007, Volume: 81, Issue:17

    Topics: Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Viral; Chromones; Enzyme Inhib

2007
CRBP suppresses breast cancer cell survival and anchorage-independent growth.
    Oncogene, 2001, Nov-01, Volume: 20, Issue:50

    Topics: Agar; Apoptosis; Breast; Breast Neoplasms; Carrier Proteins; Cell Adhesion; Cell Division; Cell Line

2001
Concomitant activation of the PI3K-Akt and the Ras-ERK signaling pathways is essential for transformation by the V-SEA tyrosine kinase oncogene.
    Oncogene, 2002, Jan-24, Volume: 21, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Division; Cell Line; Cell Line, Transformed; Cel

2002