2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
4 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Carcinoma, Oat Cell
Article | Year |
Inhibition of phosphatidylinositol 3-kinase-Akt signaling blocks growth, promotes apoptosis, and enhances sensitivity of small cell lung cancer cells to chemotherapy.Molecular cancer therapeutics, 2002, Volume: 1, Issue:11
Topics: Alleles; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Car | 2002 |
Inhibition of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway but not the MEK/ERK pathway attenuates laminin-mediated small cell lung cancer cellular survival and resistance to imatinib mesylate or chemotherapy.Cancer research, 2005, Sep-15, Volume: 65, Issue:18
Topics: Antineoplastic Agents; Benzamides; Carcinoma, Small Cell; Cell Adhesion; Cell Survival; Chromones; D | 2005 |
Constitutive activation of p70 S6 kinase is associated with intrinsic resistance to cisplatin.International journal of oncology, 2008, Volume: 32, Issue:5
Topics: Antineoplastic Agents; Apoptosis; Butadienes; Carcinoma, Small Cell; Cell Line, Tumor; Chromones; Ci | 2008 |
The presence of a constitutively active phosphoinositide 3-kinase in small cell lung cancer cells mediates anchorage-independent proliferation via a protein kinase B and p70s6k-dependent pathway.Cancer research, 1998, Nov-15, Volume: 58, Issue:22
Topics: Androstadienes; Carcinoma, Small Cell; Cell Adhesion; Cell Division; Cell Survival; Chromones; Human | 1998 |