2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Brain Infarction in 7 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
Brain Infarction: Tissue NECROSIS in any area of the brain, including the CEREBRAL HEMISPHERES, the CEREBELLUM, and the BRAIN STEM. Brain infarction is the result of a cascade of events initiated by inadequate blood flow through the brain that is followed by HYPOXIA and HYPOGLYCEMIA in brain tissue. Damage may be temporary, permanent, selective or pan-necrosis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Global cerebral ischemia was performed via 8min of four-vessel occlusion." | 1.38 | Remote ischemic postconditioning protects the brain from global cerebral ischemia/reperfusion injury by up-regulating endothelial nitric oxide synthase through the PI3K/Akt pathway. ( Guo, QL; He, ZJ; Peng, B; Wang, N; Ye, Z; Yuan, YJ; Zhou, J, 2012) |
| "Stroke was induced by middle cerebral artery occlusion for 60 min followed by reperfusion in adult male rats." | 1.38 | Stimulation of functional recovery via the mechanisms of neurorepair by S-nitrosoglutathione and motor exercise in a rat model of transient cerebral ischemia and reperfusion. ( Dhammu, TS; Khan, M; Sakakima, H; Shunmugavel, A; Singh, AK; Singh, I; Yoshida, Y, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 6 (85.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, Y | 1 |
| Zhang, X | 1 |
| Cui, H | 1 |
| Zhang, C | 1 |
| Zhu, C | 1 |
| Li, L | 1 |
| Chen, J | 1 |
| Li, J | 1 |
| Miao, Z | 1 |
| Xu, X | 1 |
| Liu, CF | 1 |
| Park, MK | 1 |
| Kang, YJ | 1 |
| Lee, HS | 1 |
| Kim, HJ | 1 |
| Seo, HG | 1 |
| Lee, JH | 1 |
| Chang, KC | 1 |
| Yuan, Y | 1 |
| Guo, Q | 1 |
| Ye, Z | 2 |
| Pingping, X | 1 |
| Wang, N | 2 |
| Song, Z | 1 |
| Peng, B | 1 |
| Guo, QL | 1 |
| He, ZJ | 1 |
| Yuan, YJ | 1 |
| Zhou, J | 1 |
| Sakakima, H | 1 |
| Khan, M | 1 |
| Dhammu, TS | 1 |
| Shunmugavel, A | 1 |
| Yoshida, Y | 1 |
| Singh, I | 1 |
| Singh, AK | 1 |
| Zhang, J | 1 |
| Deng, Z | 1 |
| Liao, J | 1 |
| Song, C | 1 |
| Liang, C | 1 |
| Xue, H | 1 |
| Wang, L | 1 |
| Zhang, K | 1 |
| Yan, G | 1 |
7 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Brain Infarction
| Article | Year |
|---|---|
Apelin-13 protects the brain against ischemia/reperfusion injury through activating PI3K/Akt and ERK1/2 signaling pathways.
Topics: Animals; Apoptosis; Brain; Brain Edema; Brain Infarction; Brain Ischemia; Caspase 3; Chromones; Enzy | 2014 |
XAV939, a small molecular inhibitor, provides neuroprotective effects on oligodentrocytes.
Topics: Animals; Animals, Newborn; Apoptosis; beta Catenin; Brain Infarction; Brain Ischemia; Caspases; Cell | 2014 |
The obligatory role of COX-2 expression for induction of HO-1 in ischemic preconditioned rat brain.
Topics: Animals; Brain; Brain Infarction; Cerebral Arteries; Chromones; Cyclooxygenase 2; Cyclooxygenase 2 I | 2008 |
Ischemic postconditioning protects brain from ischemia/reperfusion injury by attenuating endoplasmic reticulum stress-induced apoptosis through PI3K-Akt pathway.
Topics: Animals; Apoptosis; Brain; Brain Infarction; Caspase 12; Chromones; Disease Models, Animal; Endoplas | 2011 |
Remote ischemic postconditioning protects the brain from global cerebral ischemia/reperfusion injury by up-regulating endothelial nitric oxide synthase through the PI3K/Akt pathway.
Topics: Analysis of Variance; Animals; Avoidance Learning; Brain; Brain Infarction; Brain Ischemia; Cell Dea | 2012 |
Stimulation of functional recovery via the mechanisms of neurorepair by S-nitrosoglutathione and motor exercise in a rat model of transient cerebral ischemia and reperfusion.
Topics: Analysis of Variance; Animals; Apoptosis; Brain Infarction; Brain-Derived Neurotrophic Factor; Caspa | 2012 |
Leptin attenuates cerebral ischemia injury through the promotion of energy metabolism via the PI3K/Akt pathway.
Topics: Animals; Brain Edema; Brain Infarction; Chromones; Energy Metabolism; Enzyme Inhibitors; L-Lactate D | 2013 |