2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Brain Edema in 8 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diabetic patients are more vulnerable to cerebral ischemia-reperfusion (CIR) injury and have a worse prognosis and higher mortality after ischemic stroke than non-diabetic counterparts." | 5.62 | Melatonin protects against focal cerebral ischemia-reperfusion injury in diabetic mice by ameliorating mitochondrial impairments: involvement of the Akt-SIRT3-SOD2 signaling pathway. ( Cao, Q; Gao, W; Li, B; Liu, L; Xia, Z; Zhao, B, 2021) |
| "Diabetic patients are more vulnerable to cerebral ischemia-reperfusion (CIR) injury and have a worse prognosis and higher mortality after ischemic stroke than non-diabetic counterparts." | 1.62 | Melatonin protects against focal cerebral ischemia-reperfusion injury in diabetic mice by ameliorating mitochondrial impairments: involvement of the Akt-SIRT3-SOD2 signaling pathway. ( Cao, Q; Gao, W; Li, B; Liu, L; Xia, Z; Zhao, B, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, L | 1 |
| Cao, Q | 1 |
| Gao, W | 1 |
| Li, B | 1 |
| Xia, Z | 1 |
| Zhao, B | 1 |
| Zhu, Q | 1 |
| Enkhjargal, B | 1 |
| Huang, L | 1 |
| Zhang, T | 1 |
| Sun, C | 1 |
| Xie, Z | 2 |
| Wu, P | 1 |
| Mo, J | 1 |
| Tang, J | 1 |
| Zhang, JH | 1 |
| Yang, Y | 1 |
| Zhang, X | 1 |
| Cui, H | 1 |
| Zhang, C | 1 |
| Zhu, C | 1 |
| Li, L | 1 |
| Hao, XK | 1 |
| Wu, W | 1 |
| Wang, CX | 1 |
| Xie, GB | 1 |
| Li, T | 1 |
| Wu, HM | 1 |
| Huang, LT | 1 |
| Zhou, ML | 1 |
| Hang, CH | 1 |
| Shi, JX | 1 |
| Sun, N | 1 |
| Wang, H | 1 |
| Ma, L | 1 |
| Lei, P | 1 |
| Zhang, Q | 1 |
| Chen, SF | 1 |
| Tsai, HJ | 1 |
| Hung, TH | 1 |
| Chen, CC | 1 |
| Lee, CY | 1 |
| Wu, CH | 1 |
| Wang, PY | 1 |
| Liao, NC | 1 |
| Zhang, J | 1 |
| Deng, Z | 1 |
| Liao, J | 1 |
| Song, C | 1 |
| Liang, C | 1 |
| Xue, H | 1 |
| Wang, L | 1 |
| Zhang, K | 1 |
| Yan, G | 1 |
| Niyaz, M | 1 |
| Numakawa, T | 1 |
| Matsuki, Y | 1 |
| Kumamaru, E | 1 |
| Adachi, N | 1 |
| Kitazawa, H | 1 |
| Kunugi, H | 1 |
| Kudo, M | 1 |
8 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Brain Edema
| Article | Year |
|---|---|
Melatonin protects against focal cerebral ischemia-reperfusion injury in diabetic mice by ameliorating mitochondrial impairments: involvement of the Akt-SIRT3-SOD2 signaling pathway.
Topics: Animals; Apoptosis; Brain Edema; Brain Ischemia; Cell Line; Cell Survival; Chromones; Diabetes Melli | 2021 |
Aggf1 attenuates neuroinflammation and BBB disruption via PI3K/Akt/NF-κB pathway after subarachnoid hemorrhage in rats.
Topics: Angiogenic Proteins; Animals; Blood-Brain Barrier; Brain Edema; Capillary Permeability; Chromones; D | 2018 |
Apelin-13 protects the brain against ischemia/reperfusion injury through activating PI3K/Akt and ERK1/2 signaling pathways.
Topics: Animals; Apoptosis; Brain; Brain Edema; Brain Infarction; Brain Ischemia; Caspase 3; Chromones; Enzy | 2014 |
Ghrelin alleviates early brain injury after subarachnoid hemorrhage via the PI3K/Akt signaling pathway.
Topics: Animals; Apoptosis; Brain Damage, Chronic; Brain Edema; Caspase 3; Chromones; Enzyme Induction; Ghre | 2014 |
Ghrelin attenuates brain injury in septic mice via PI3K/Akt signaling activation.
Topics: Animals; bcl-2-Associated X Protein; Blood-Brain Barrier; Brain Edema; Brain Injuries; Capillary Per | 2016 |
Salidroside improves behavioral and histological outcomes and reduces apoptosis via PI3K/Akt signaling after experimental traumatic brain injury.
Topics: Antioxidants; Apoptosis; Brain Edema; Brain Injuries; Cells, Cultured; Cerebral Cortex; Chromones; D | 2012 |
Leptin attenuates cerebral ischemia injury through the promotion of energy metabolism via the PI3K/Akt pathway.
Topics: Animals; Brain Edema; Brain Infarction; Chromones; Energy Metabolism; Enzyme Inhibitors; L-Lactate D | 2013 |
MCI-186 prevents brain tissue from neuronal damage in cerebral infarction through the activation of intracellular signaling.
Topics: Animals; Animals, Newborn; Antipyrine; Brain Edema; Butadienes; Cell Death; Cells, Cultured; Cerebra | 2007 |