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2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Blood Pressure, High

2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Blood Pressure, High in 8 studies

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source

Research Excerpts

ExcerptRelevanceReference
"Hypertension is characterized by abnormal vascular contractility and function."1.32Rho/Rho kinase and phosphoinositide 3-kinase are parallel pathways in the development of spontaneous arterial tone in deoxycorticosterone acetate-salt hypertension. ( Loberg, RD; Northcott, CA; Watts, SW; Wehrwein, EA, 2004)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (62.50)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gandhi, H1
Naik, P1
Agrawal, N1
Yadav, M1
Zhang, L1
Xie, P1
Wang, J1
Yang, Q1
Fang, C1
Zhou, S1
Li, J1
Benter, IF1
Al-Rashdan, I1
Juggi, JS1
Yousif, MH1
Akhtar, S1
Loberg, RD2
Northcott, CA4
Watts, SW4
Brosius, FC1
Wehrwein, EA1
Hayflick, JS1
McCallum, RW1
Hamilton, CA1
Graham, D1
Jardine, E1
Connell, JM1
Dominiczak, AF1
Hayflick, J1

Other Studies

8 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Blood Pressure, High

ArticleYear
Protective effects of MCR-1329, a dual α1 and angII receptor antagonist, in mineralocorticoid-induced hypertension.
    Pharmacological reports : PR, 2016, Volume: 68, Issue:5

    Topics: Adrenergic alpha-1 Receptor Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals;

2016
Impaired peroxisome proliferator-activated receptor-gamma contributes to phenotypic modulation of vascular smooth muscle cells during hypertension.
    The Journal of biological chemistry, 2010, Apr-30, Volume: 285, Issue:18

    Topics: Animals; Aorta; Cell Movement; Cell Proliferation; Chromones; Enzyme Inhibitors; Gene Expression Reg

2010
Chronic treatment with LY294002, an inhibitor of phosphatidylinositol 3-kinase, attenuates ischemia/reperfusion-induced cardiac dysfunction in normotensive and hypertensive diabetic animals.
    Molecular and cellular biochemistry, 2013, Volume: 373, Issue:1-2

    Topics: Animals; Cardiotonic Agents; Chromones; Coronary Vessels; Diabetes Mellitus, Experimental; Hypertens

2013
PI3-kinase-induced hyperreactivity in DOCA-salt hypertension is independent of GSK-3 activity.
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:4

    Topics: Aminophenols; Animals; Arteries; Chromones; Culture Techniques; Desoxycorticosterone; Enzyme Inhibit

2003
Rho/Rho kinase and phosphoinositide 3-kinase are parallel pathways in the development of spontaneous arterial tone in deoxycorticosterone acetate-salt hypertension.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 309, Issue:3

    Topics: Amides; Animals; Arteries; Calcium; Chromones; Desoxycorticosterone; Enzyme Inhibitors; Hypertension

2004
PI3-kinase upregulation and involvement in spontaneous tone in arteries from DOCA-salt rats: is p110delta the culprit?
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:4

    Topics: Adenine; Animals; Aorta; Chromones; Class I Phosphatidylinositol 3-Kinases; Desoxycorticosterone; Di

2004
Vascular responses to IGF-I and insulin are impaired in aortae of hypertensive rats.
    Journal of hypertension, 2005, Volume: 23, Issue:2

    Topics: Androstadienes; Animals; Aorta, Thoracic; Chromones; Endothelin-1; Enzyme Inhibitors; Female; Hypert

2005
Upregulated function of phosphatidylinositol-3-kinase in genetically hypertensive rats: a moderator of arterial hypercontractility.
    Clinical and experimental pharmacology & physiology, 2005, Volume: 32, Issue:10

    Topics: Adenine; Animals; Aorta; Blotting, Western; Chromones; Dose-Response Relationship, Drug; Endothelium

2005