2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Bile Duct Cancer in 7 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| "The prognosis for patients with bile duct cancer (BDC) remains poor." | 1.32 | Serine/threonine kinase AKT is frequently activated in human bile duct cancer and is associated with increased radioresistance. ( Habiro, A; Kohgo, Y; Koizumi, K; Mizukami, Y; Nakano, Y; Okumura, T; Osanai, M; Tanno, S; Testa, JR; Yanagawa, N, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, R | 1 |
| He, F | 1 |
| He, H | 1 |
| York, JP | 1 |
| Liu, W | 1 |
| Xia, X | 1 |
| Liu, CH | 1 |
| Huang, Q | 1 |
| Jin, ZY | 1 |
| Zhu, CL | 1 |
| Liu, Z | 1 |
| Wang, C | 1 |
| Leelawat, K | 2 |
| Udomchaiprasertkul, W | 1 |
| Narong, S | 2 |
| Leelawat, S | 2 |
| Tanno, S | 1 |
| Yanagawa, N | 1 |
| Habiro, A | 1 |
| Koizumi, K | 1 |
| Nakano, Y | 1 |
| Osanai, M | 1 |
| Mizukami, Y | 1 |
| Okumura, T | 1 |
| Testa, JR | 1 |
| Kohgo, Y | 1 |
| Miyata, H | 1 |
| Sasaki, T | 1 |
| Kuwahara, K | 1 |
| Serikawa, M | 1 |
| Chayama, K | 1 |
| Hongeng, S | 1 |
| Feranchak, AP | 1 |
| Roman, RM | 1 |
| Doctor, RB | 1 |
| Salter, KD | 1 |
| Toker, A | 1 |
| Fitz, JG | 1 |
7 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Bile Duct Cancer
| Article | Year |
|---|---|
Phosphorylation of P27 by AKT is required for inhibition of cell cycle progression in cholangiocarcinoma.
Topics: Bile Duct Neoplasms; Butadienes; Cell Line, Tumor; Cell Movement; Cholangiocarcinoma; Chromones; Cyc | 2018 |
miR-21 and KLF4 jointly augment epithelial‑mesenchymal transition via the Akt/ERK1/2 pathway.
Topics: Antigens, CD; Bile Duct Neoplasms; Butadienes; Cadherins; Cell Line, Tumor; Cell Movement; Cholangio | 2017 |
Induction of MKP-1 prevents the cytotoxic effects of PI3K inhibition in hilar cholangiocarcinoma cells.
Topics: Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cell Line, Tumor; Cell Survival; Cholangiocarcinoma; | 2010 |
Serine/threonine kinase AKT is frequently activated in human bile duct cancer and is associated with increased radioresistance.
Topics: Bile Duct Neoplasms; Cell Line, Tumor; Cell Survival; Chromones; Enzyme Activation; Enzyme Inhibitor | 2004 |
The effects of ZD1839 (Iressa), a highly selective EGFR tyrosine kinase inhibitor, as a radiosensitiser in bile duct carcinoma cell lines.
Topics: Anthracenes; Bile Duct Neoplasms; Butadienes; Cell Line, Tumor; Cell Proliferation; Cell Survival; C | 2006 |
Roles of the MEK1/2 and AKT pathways in CXCL12/CXCR4 induced cholangiocarcinoma cell invasion.
Topics: Benzylamines; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Butadienes; Cell Line, Tumor; Chemokine | 2007 |
The lipid products of phosphoinositide 3-kinase contribute to regulation of cholangiocyte ATP and chloride transport.
Topics: Adenosine Triphosphate; Androstadienes; Animals; Bile Duct Neoplasms; Bile Ducts; Bile Ducts, Intrah | 1999 |