2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Barrett Esophagus in 2 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
Barrett Esophagus: A condition with damage to the lining of the lower ESOPHAGUS resulting from chronic acid reflux (ESOPHAGITIS, REFLUX). Through the process of metaplasia, the squamous cells are replaced by a columnar epithelium with cells resembling those of the INTESTINE or the salmon-pink mucosa of the STOMACH. Barrett's columnar epithelium is a marker for severe reflux and precursor to ADENOCARCINOMA of the esophagus.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The Barrett's adenocarcinoma cell line, SEG-1, was exposed to the conjugated bile salt, glycochenodeoxycholic acid (GCDA)." | 3.72 | Bile salt exposure causes phosphatidyl-inositol-3-kinase-mediated proliferation in a Barrett's adenocarcinoma cell line. ( Anthony, T; Jaiswal, K; Lopez-Guzman, C; Nwariaku, F; Sarosi, GA; Tello, V, 2004) |
| "Necrosis was significantly reduced (P < 0." | 1.33 | MAPK and PI3K inhibition reduces proliferation of Barrett's adenocarcinoma in vitro. ( Cunningham, C; Frankenberry, K; Jackson, BJ; McFadden, DW; Riggs, DR; Szwerc, MF; Vona-Davis, L, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jaiswal, K | 1 |
| Tello, V | 1 |
| Lopez-Guzman, C | 1 |
| Nwariaku, F | 1 |
| Anthony, T | 1 |
| Sarosi, GA | 1 |
| Vona-Davis, L | 1 |
| Frankenberry, K | 1 |
| Cunningham, C | 1 |
| Riggs, DR | 1 |
| Jackson, BJ | 1 |
| Szwerc, MF | 1 |
| McFadden, DW | 1 |
2 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Barrett Esophagus
| Article | Year |
|---|---|
Bile salt exposure causes phosphatidyl-inositol-3-kinase-mediated proliferation in a Barrett's adenocarcinoma cell line.
Topics: Adenocarcinoma; Apoptosis; Barrett Esophagus; Caspases; Cell Division; Cell Line, Tumor; Chromones; | 2004 |
MAPK and PI3K inhibition reduces proliferation of Barrett's adenocarcinoma in vitro.
Topics: Adenocarcinoma; Apoptosis; Barrett Esophagus; Butadienes; Cell Division; Cell Line, Tumor; Cell Surv | 2005 |