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2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Atherogenesis

2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Atherogenesis in 17 studies

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source

Research Excerpts

ExcerptRelevanceReference
"The data demonstrate that IL-4 up-regulates the expression of MCP-1 and decreases NO bioavailability through activation of NADPH oxidase in endothelial cells."1.33Pro-atherogenic effect of interleukin-4 in endothelial cells: modulation of oxidative stress, nitric oxide and monocyte chemoattractant protein-1 expression. ( Brunet, A; Dufilho, M; Massade, L; Rendu, F; Walch, L, 2006)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (23.53)29.6817
2010's13 (76.47)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alyahya, AM1
Al-Masri, A1
Hersi, A1
El Eter, E1
Husain, S1
Lateef, R1
Mawlana, OH1
Yang, N1
Yao, S1
Wang, M1
Jiao, P1
Zhang, Y2
Qin, S1
Wang, B1
Zhang, L2
Zhang, T1
Wang, H2
Zhang, J1
Wei, J1
Shen, B1
Liu, X1
Xu, Z1
Zhai, C1
Cheng, J1
Mujahid, H1
Kong, J1
Yin, Y2
Li, J1
Ji, X1
Chen, W1
Liu, W1
Jiang, J1
Yan, D1
Li, D1
Li, W1
Ma, Y1
Yang, L1
Qu, Z1
Ruan, Q1
Michael, DR1
Davies, TS1
Laubertová, L1
Gallagher, H1
Ramji, DP1
Jiang, Q1
Han, Y1
Gao, H1
Tian, R1
Li, P1
Wang, C1
Zong, J1
Li, Y2
Du, D1
Liu, Y1
Kou, JY1
Zhong, ZY1
Jiang, YQ1
Li, XS1
Han, XB1
Liu, ZN1
Tian, Y2
Yang, LM1
Zhao, Y1
Wang, L1
He, S1
Wang, X1
Shi, W1
Kawahara, K1
Hashiguchi, T1
Kikuchi, K1
Tancharoen, S1
Miura, N1
Ito, T1
Oyama, Y1
Nawa, Y1
Biswas, KK1
Meng, X1
Morimoto, Y1
Shrestha, B1
Sameshima, H1
Maruyama, I1
Boyanovsky, BB1
Shridas, P1
Simons, M1
van der Westhuyzen, DR1
Webb, NR1
Li, HX1
Kong, FJ1
Bai, SZ1
He, W1
Xing, WJ1
Xi, YH1
Li, GW1
Guo, J1
Li, HZ1
Wu, LY1
Wang, R1
Yang, GD1
Xu, CQ1
Badrnya, S1
Butler, LM1
Söderberg-Naucler, C1
Volf, I1
Assinger, A1
Huang, WC1
Sala-Newby, GB1
Susana, A1
Johnson, JL1
Newby, AC1
Walch, L1
Massade, L1
Dufilho, M1
Brunet, A1
Rendu, F1
van Thienen, JV1
Fledderus, JO1
Dekker, RJ1
Rohlena, J1
van Ijzendoorn, GA1
Kootstra, NA1
Pannekoek, H1
Horrevoets, AJ1

Other Studies

17 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Atherogenesis

ArticleYear
The Effects of Progranulin in a Rat Model of Acute Myocardial Ischemia/Reperfusion are Mediated by Activation of the P13K/Akt Signaling Pathway.
    Medical science monitor basic research, 2019, Nov-07, Volume: 25

    Topics: Adipokines; Animals; Apoptosis; Atherosclerosis; Chromones; Disease Models, Animal; Male; Morpholine

2019
Apolipoprotein A-I mimetic peptide reverse D-4F improves the biological functions of mouse bone marrow-derived late EPCs via PI3K/AKT/eNOS pathway.
    Molecular and cellular biochemistry, 2013, Volume: 377, Issue:1-2

    Topics: Amino Acid Sequence; Animals; Apolipoprotein A-I; Atherosclerosis; Bone Marrow Cells; Cell Movement;

2013
Chlamydia pneumoniae infection promotes vascular smooth muscle cell migration through a Toll-like receptor 2-related signaling pathway.
    Infection and immunity, 2013, Volume: 81, Issue:12

    Topics: Animals; Antibodies, Neutralizing; Atherosclerosis; Cell Movement; Chlamydia Infections; Chlamydophi

2013
Selective inhibition of PI3K/Akt/mTOR signaling pathway regulates autophagy of macrophage and vulnerability of atherosclerotic plaque.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Animals; Atherosclerosis; Autophagy; Cells, Cultured; Chromones; Cytokines; Lipids; Macrophages, Per

2014
Pentraxin 3 promotes oxLDL uptake and inhibits cholesterol efflux from macrophage-derived foam cells.
    Experimental and molecular pathology, 2014, Volume: 96, Issue:3

    Topics: Apolipoprotein A-I; Atherosclerosis; ATP Binding Cassette Transporter 1; C-Reactive Protein; Cell Li

2014
The phosphoinositide 3-kinase signaling pathway is involved in the control of modified low-density lipoprotein uptake by human macrophages.
    Lipids, 2015, Volume: 50, Issue:3

    Topics: Atherosclerosis; Chromones; Foam Cells; Gene Expression; Humans; Lipoproteins, LDL; Macrophages; Mor

2015
Ursolic acid induced anti-proliferation effects in rat primary vascular smooth muscle cells is associated with inhibition of microRNA-21 and subsequent PTEN/PI3K.
    European journal of pharmacology, 2016, Jun-15, Volume: 781

    Topics: Animals; Atherosclerosis; Cell Proliferation; Chromones; Gene Expression Regulation; Gene Expression

2016
CD147 induces up-regulation of vascular endothelial growth factor in U937-derived foam cells through PI3K/AKT pathway.
    Archives of biochemistry and biophysics, 2016, Nov-01, Volume: 609

    Topics: Anthracenes; Atherosclerosis; Basigin; Butadienes; Chromones; Flow Cytometry; Foam Cells; Gene Expre

2016
Berberine-sonodynamic therapy induces autophagy and lipid unloading in macrophage.
    Cell death & disease, 2017, 01-19, Volume: 8, Issue:1

    Topics: Atherosclerosis; Autophagy; Berberine; Cell Survival; Cholesterol; Chromones; Humans; Lipids; Macrop

2017
Nitric oxide synthesis-promoting effects of valsartan in human umbilical vein endothelial cells via the Akt/adenosine monophosphate-activated protein kinase/endothelial nitric oxide synthase pathway.
    Bosnian journal of basic medical sciences, 2017, May-20, Volume: 17, Issue:2

    Topics: Adenosine Monophosphate; AMP-Activated Protein Kinases; Antihypertensive Agents; Atherosclerosis; Ch

2017
Induction of high mobility group box 1 release from serotonin-stimulated human umbilical vein endothelial cells.
    International journal of molecular medicine, 2008, Volume: 22, Issue:5

    Topics: Animals; Atherosclerosis; Cell Line; Cell Nucleus; Chromones; Endothelial Cells; Enzyme Inhibitors;

2008
Syndecan-4 mediates macrophage uptake of group V secretory phospholipase A2-modified LDL.
    Journal of lipid research, 2009, Volume: 50, Issue:4

    Topics: Animals; Atherosclerosis; Base Sequence; Biological Transport, Active; Cell Line; Cells, Cultured; C

2009
Involvement of calcium-sensing receptor in oxLDL-induced MMP-2 production in vascular smooth muscle cells via PI3K/Akt pathway.
    Molecular and cellular biochemistry, 2012, Volume: 362, Issue:1-2

    Topics: Adamantane; Animals; Anthracenes; Aorta; Atherosclerosis; Cells, Cultured; Chromones; Gadolinium; JN

2012
Platelets directly enhance neutrophil transmigration in response to oxidised low-density lipoprotein.
    Thrombosis and haemostasis, 2012, Volume: 108, Issue:4

    Topics: Aspirin; Atherosclerosis; Blood Platelets; CD11b Antigen; Cell Aggregation; Cell Communication; Cell

2012
Classical macrophage activation up-regulates several matrix metalloproteinases through mitogen activated protein kinases and nuclear factor-κB.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Atherosclerosis; Cell Adhesion; Chromones; Enzyme Activation; Gene Expression Regulation, Enzymologi

2012
Pro-atherogenic effect of interleukin-4 in endothelial cells: modulation of oxidative stress, nitric oxide and monocyte chemoattractant protein-1 expression.
    Atherosclerosis, 2006, Volume: 187, Issue:2

    Topics: Arachidonic Acids; Atherosclerosis; Chemokine CCL2; Chromones; Endothelium, Vascular; Enzyme Inhibit

2006
Shear stress sustains atheroprotective endothelial KLF2 expression more potently than statins through mRNA stabilization.
    Cardiovascular research, 2006, Nov-01, Volume: 72, Issue:2

    Topics: Atherosclerosis; Cells, Cultured; Chromones; Endothelial Cells; Endothelium, Vascular; Fluorescent A

2006