2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Allodynia in 5 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| "Therefore, PI3K induces heat hyperalgesia, possibly by regulating TRPV1 activity, in an ERK-dependent manner." | 1.32 | Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization. ( Clapham, DE; Ji, RR; Xu, H; Zhuang, ZY, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shen, S | 1 |
| Al-Thumairy, HW | 1 |
| Hashmi, F | 1 |
| Qiao, LY | 1 |
| Yan, Y | 1 |
| Liang, Y | 1 |
| Ding, T | 1 |
| Chu, H | 1 |
| Xu, B | 1 |
| Mo, C | 1 |
| Lv, C | 1 |
| Liu, S | 1 |
| Li, J | 1 |
| Chen, J | 1 |
| Wei, Y | 1 |
| An, H | 1 |
| Ma, L | 1 |
| Guan, X | 1 |
| Jin, D | 1 |
| Yang, JP | 1 |
| Hu, JH | 1 |
| Wang, LN | 1 |
| Zuo, JL | 1 |
| Zhuang, ZY | 1 |
| Xu, H | 1 |
| Clapham, DE | 1 |
| Ji, RR | 1 |
5 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Allodynia
| Article | Year |
|---|---|
Regulation of transient receptor potential cation channel subfamily V1 protein synthesis by the phosphoinositide 3-kinase/Akt pathway in colonic hypersensitivity.
Topics: Animals; Chromones; Colitis; Ganglia, Spinal; Hyperalgesia; Hypersensitivity; Male; Morpholines; Ner | 2017 |
PI3K/Akt signaling pathway may be involved in MCP-1-induced P2X4R expression in cultured microglia and cancer-induced bone pain rats.
Topics: Animals; Benzoxazines; Calcium-Binding Proteins; Cancer Pain; Cell Line, Tumor; Chemokine CCL2; Chro | 2019 |
Post-surgical inhibition of phosphatidylinositol 3-kinase attenuates the plantar incision-induced postoperative pain behavior via spinal Akt activation in male mice.
Topics: Animals; Chromones; Female; Foot Injuries; Hyperalgesia; Male; Mice; Morpholines; Pain Measurement; | 2019 |
MCP-1 stimulates spinal microglia via PI3K/Akt pathway in bone cancer pain.
Topics: Animals; Bone Neoplasms; Carcinoma, Ductal, Breast; Cell Line, Tumor; Chemokine CCL2; Chromones; Enz | 2015 |
Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization.
Topics: Androstadienes; Animals; Capsaicin; Cells, Cultured; Chromones; Enzyme Activation; Enzyme Inhibitors | 2004 |