2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Akinetic-Rigid Variant of Huntington Disease in 3 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| "Here we demonstrate in precise genetic Huntington's disease mouse and striatal cell models that these early phenotypes are associated with activation of the Akt pro-survival signaling pathway." | 1.32 | Enhanced Akt signaling is an early pro-survival response that reflects N-methyl-D-aspartate receptor activation in Huntington's disease knock-in striatal cells. ( Gines, S; Ivanova, E; MacDonald, ME; Saura, CA; Seong, IS, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, T | 1 |
| Dong, K | 1 |
| Liang, W | 1 |
| Xu, D | 1 |
| Xia, H | 1 |
| Geng, J | 1 |
| Najafov, A | 1 |
| Liu, M | 1 |
| Li, Y | 1 |
| Han, X | 1 |
| Xiao, J | 1 |
| Jin, Z | 1 |
| Peng, T | 2 |
| Gao, Y | 1 |
| Cai, Y | 1 |
| Qi, C | 1 |
| Zhang, Q | 1 |
| Sun, A | 1 |
| Lipinski, M | 1 |
| Zhu, H | 1 |
| Xiong, Y | 1 |
| Pandolfi, PP | 1 |
| Li, H | 2 |
| Yu, Q | 1 |
| Yuan, J | 1 |
| Fang, F | 1 |
| Yang, S | 1 |
| Wang, W | 1 |
| Zhang, Y | 1 |
| Gines, S | 1 |
| Ivanova, E | 1 |
| Seong, IS | 1 |
| Saura, CA | 1 |
| MacDonald, ME | 1 |
3 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
G-protein-coupled receptors regulate autophagy by ZBTB16-mediated ubiquitination and proteasomal degradation of Atg14L.
Topics: Animals; Autophagy; Autophagy-Related Proteins; Benzylamines; Carrier Proteins; Cell Line, Tumor; Ch | 2015 |
Lycium barbarum polysaccharide attenuates the cytotoxicity of mutant huntingtin and increases the activity of AKT.
Topics: Analysis of Variance; Animals; Brain; Caspase 3; Cell Survival; Chromones; Disease Models, Animal; D | 2016 |
Enhanced Akt signaling is an early pro-survival response that reflects N-methyl-D-aspartate receptor activation in Huntington's disease knock-in striatal cells.
Topics: Alleles; Animals; beta Catenin; Cell Membrane; Cells, Cultured; Chromones; Corpus Striatum; Cyclin D | 2003 |