2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Aging in 14 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Type 2 diabetes mellitus is thought to be a significant risk factor for Alzheimer's disease." | 1.38 | Brain insulin resistance accelerates Aβ fibrillogenesis by inducing GM1 ganglioside clustering in the presynaptic membranes. ( Kasahara, R; Matsubara, T; Naruse, K; Sato, T; Sobue, K; Suzuki, K; Tanida, M; Taniura, H; Yamamoto, N, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 7 (50.00) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, S | 1 |
| Liu, Y | 1 |
| Huang, S | 1 |
| Jin, F | 1 |
| Qi, F | 1 |
| Weh, E | 1 |
| Lutrzykowska, Z | 1 |
| Smith, A | 1 |
| Hager, H | 1 |
| Pawar, M | 1 |
| Wubben, TJ | 1 |
| Besirli, CG | 1 |
| Slouzkey, I | 1 |
| Maroun, M | 1 |
| Li, M | 1 |
| Chiu, JF | 1 |
| Gagne, J | 1 |
| Fukagawa, NK | 1 |
| Bouraïma-Lelong, H | 1 |
| Vanneste, M | 1 |
| Delalande, C | 1 |
| Zanatta, L | 1 |
| Wolczynski, S | 1 |
| Carreau, S | 1 |
| Chen, T | 1 |
| Shen, L | 1 |
| Yu, J | 1 |
| Wan, H | 1 |
| Guo, A | 1 |
| Chen, J | 1 |
| Long, Y | 1 |
| Zhao, J | 1 |
| Pei, G | 1 |
| Yamamoto, N | 1 |
| Matsubara, T | 1 |
| Sobue, K | 1 |
| Tanida, M | 1 |
| Kasahara, R | 1 |
| Naruse, K | 1 |
| Taniura, H | 1 |
| Sato, T | 1 |
| Suzuki, K | 1 |
| Maher, FO | 1 |
| Martin, DS | 1 |
| Lynch, MA | 1 |
| Wang, MJ | 1 |
| Lin, SZ | 1 |
| Kuo, JS | 1 |
| Huang, HY | 1 |
| Tzeng, SF | 1 |
| Liao, CH | 1 |
| Chen, DC | 1 |
| Chen, WF | 1 |
| Song, H | 1 |
| Zhang, Z | 1 |
| Wang, L | 1 |
| Ward, SM | 1 |
| Brennan, MF | 1 |
| Jackson, VM | 1 |
| Sanders, KM | 1 |
| Dardevet, D | 1 |
| Sornet, C | 1 |
| Balage, M | 1 |
| Grizard, J | 1 |
| Ikeyama, S | 1 |
| Kokkonen, G | 1 |
| Shack, S | 1 |
| Wang, XT | 1 |
| Holbrook, NJ | 1 |
| Srinivasan, S | 1 |
| Strange, J | 1 |
| Awonusonu, F | 1 |
| Bruce, MC | 1 |
14 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Aging
| Article | Year |
|---|---|
Sevoflurane and isoflurane inhibit KCl-induced, Rho kinase-mediated, and PI3K-participated vasoconstriction in aged diabetic rat aortas.
Topics: Aging; Amides; Anesthetics, Inhalation; Animals; Aorta; Chromones; Diabetes Mellitus, Experimental; | 2021 |
Hexokinase 2 is dispensable for photoreceptor development but is required for survival during aging and outer retinal stress.
Topics: Aging; Animals; Caspases; Cell Survival; Chromones; Cytosol; Enzyme Activation; Gene Knockdown Techn | 2020 |
PI3-kinase cascade has a differential role in acquisition and extinction of conditioned fear memory in juvenile and adult rats.
Topics: Aging; Animals; Basolateral Nuclear Complex; Chromones; Conditioning, Psychological; Enzyme Inhibito | 2016 |
Age-related differences in insulin-like growth factor-1 receptor signaling regulates Akt/FOXO3a and ERK/Fos pathways in vascular smooth muscle cells.
Topics: Age Factors; Aging; Animals; Catalase; Cells, Cultured; Chromones; Crosses, Genetic; Cyclin-Dependen | 2008 |
Aromatase gene expression in immature rat Sertoli cells: age-related changes in the FSH signalling pathway.
Topics: Age Factors; Aging; Analysis of Variance; Animals; Aromatase; Blood-Testis Barrier; Cells, Cultured; | 2010 |
Rapamycin and other longevity-promoting compounds enhance the generation of mouse induced pluripotent stem cells.
Topics: Aging; Animals; Cellular Reprogramming; Chromones; Flavonoids; Flavonols; Induced Pluripotent Stem C | 2011 |
Brain insulin resistance accelerates Aβ fibrillogenesis by inducing GM1 ganglioside clustering in the presynaptic membranes.
Topics: Aging; Amyloid beta-Peptides; Animals; Blotting, Western; Brain Chemistry; Cell Separation; Cells, C | 2012 |
Increased IL-1beta in cortex of aged rats is accompanied by downregulation of ERK and PI-3 kinase.
Topics: Aging; Animals; Bacterial Proteins; Blotting, Western; Brain-Derived Neurotrophic Factor; Butadienes | 2004 |
Urocortin modulates inflammatory response and neurotoxicity induced by microglial activation.
Topics: Aging; Animals; Cell Death; Cells, Cultured; Chromones; Cyclic AMP; Enzyme Activation; Glycogen Synt | 2007 |
Small interference RNA against PTP-1B reduces hypoxia/reoxygenation induced apoptosis of rat cardiomyocytes.
Topics: Aging; Animals; Apoptosis; Caspase Inhibitors; Cells, Cultured; Chromones; Hypoxia; In Situ Nick-End | 2008 |
Role of PI3-kinase in the development of interstitial cells and pacemaking in murine gastrointestinal smooth muscle.
Topics: Aging; Androstadienes; Animals; Animals, Newborn; Biological Clocks; Chromones; Digestive System; El | 1999 |
Stimulation of in vitro rat muscle protein synthesis by leucine decreases with age.
Topics: Aging; Amino Acids; Animals; Chromones; Enzyme Inhibitors; Flavonoids; Immunosuppressive Agents; Leu | 2000 |
Loss in oxidative stress tolerance with aging linked to reduced extracellular signal-regulated kinase and Akt kinase activities.
Topics: Aging; Animals; Cell Survival; Cells, Cultured; Chromones; Drug Synergism; Energy Intake; Enzyme Inh | 2002 |
Insulin-like growth factor I receptor is downregulated after alveolarization in an apoptotic fibroblast subset.
Topics: Aging; Animals; Animals, Newborn; Apoptosis; Cell Membrane; Cell Survival; Cells, Cultured; Chromone | 2002 |