2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one has been researched along with Acute Confusional Senile Dementia in 12 studies
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one: specific inhibitor of phosphatidylinositol 3-kinase; structure in first source
| Excerpt | Relevance | Reference |
|---|---|---|
| "Linagliptin is an inhibitor of dipeptidylpeptidase-4 (DPP-4), which improves impaired insulin secretion and insulin downstream signaling in the in peripheral tissues." | 1.42 | DPP-4 Inhibitor Linagliptin Attenuates Aβ-induced Cytotoxicity through Activation of AMPK in Neuronal Cells. ( Chang, HH; Huang, CN; Huang, WN; Kornelius, E; Li, HH; Lin, CL; Lu, YL; Peng, CH; Yang, YS, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 8 (66.67) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Hajjo, R | 1 |
| Setola, V | 1 |
| Roth, BL | 1 |
| Tropsha, A | 1 |
| Yoon, JH | 1 |
| Lee, N | 1 |
| Youn, K | 1 |
| Jo, MR | 1 |
| Kim, HR | 1 |
| Lee, DS | 1 |
| Ho, CT | 1 |
| Jun, M | 1 |
| Cui, W | 1 |
| Wang, S | 2 |
| Wang, Z | 2 |
| Sun, C | 1 |
| Zhang, Y | 1 |
| Sun, Q | 1 |
| Jia, N | 1 |
| Li, X | 1 |
| Yang, J | 1 |
| Chen, G | 1 |
| Zhu, X | 1 |
| Yu, L | 1 |
| Yang, H | 1 |
| Tan, R | 1 |
| Yin, K | 1 |
| Jin, J | 1 |
| Zhao, H | 1 |
| Guan, D | 1 |
| Xu, Y | 1 |
| Wan, Z | 1 |
| Mah, D | 1 |
| Simtchouk, S | 1 |
| Kluftinger, A | 1 |
| Little, JP | 1 |
| Kornelius, E | 1 |
| Lin, CL | 1 |
| Chang, HH | 1 |
| Li, HH | 1 |
| Huang, WN | 1 |
| Yang, YS | 1 |
| Lu, YL | 1 |
| Peng, CH | 1 |
| Huang, CN | 1 |
| Copanaki, E | 1 |
| Chang, S | 1 |
| Vlachos, A | 1 |
| Tschäpe, JA | 1 |
| Müller, UC | 1 |
| Kögel, D | 1 |
| Deller, T | 1 |
| Durairajan, SS | 1 |
| Liu, LF | 1 |
| Lu, JH | 1 |
| Chen, LL | 1 |
| Yuan, Q | 1 |
| Chung, SK | 1 |
| Huang, L | 1 |
| Li, XS | 1 |
| Huang, JD | 1 |
| Li, M | 1 |
| Parvathenani, LK | 1 |
| Tertyshnikova, S | 1 |
| Greco, CR | 1 |
| Roberts, SB | 1 |
| Robertson, B | 1 |
| Posmantur, R | 1 |
| Baki, L | 1 |
| Neve, RL | 1 |
| Shao, Z | 1 |
| Shioi, J | 1 |
| Georgakopoulos, A | 1 |
| Robakis, NK | 1 |
| Zhang, L | 1 |
| Rubinow, DR | 1 |
| Xaing , G | 1 |
| Li, BS | 1 |
| Chang, YH | 1 |
| Maric, D | 1 |
| Barker, JL | 1 |
| Ma, W | 1 |
12 other studies available for 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Chemocentric informatics approach to drug discovery: identification and experimental validation of selective estrogen receptor modulators as ligands of 5-hydroxytryptamine-6 receptors and as potential cognition enhancers.
Topics: Alzheimer Disease; Cell Line, Tumor; Cloning, Molecular; Cognition; Drug Discovery; Drug Evaluation, | 2012 |
Dieckol Ameliorates Aβ Production via PI3K/Akt/GSK-3β Regulated APP Processing in SweAPP N2a Cell.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Benzofurans; Cell | 2021 |
Inhibition of PTEN Attenuates Endoplasmic Reticulum Stress and Apoptosis via Activation of PI3K/AKT Pathway in Alzheimer's Disease.
Topics: Alzheimer Disease; Animals; Apoptosis; Chromones; Endoplasmic Reticulum Chaperone BiP; Endoplasmic R | 2017 |
Grape seed proanthocyanidins ameliorate neuronal oxidative damage by inhibiting GSK-3β-dependent mitochondrial permeability transition pore opening in an experimental model of sporadic Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Cerebral Cortex; Chromones; Glycogen Synthase Kinase 3 beta; Grape Seed | 2019 |
TL-2 attenuates β-amyloid induced neuronal apoptosis through the AKT/GSK-3β/β-catenin pathway.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; beta Catenin; Caspase 3; Caspase 9; Ce | 2014 |
Human adipose tissue conditioned media from lean subjects is protective against H2O2 induced neurotoxicity in human SH-SY5Y neuronal cells.
Topics: Adipose Tissue; Alzheimer Disease; Anthracenes; Cell Line, Tumor; Cell Survival; Chromones; Culture | 2015 |
DPP-4 Inhibitor Linagliptin Attenuates Aβ-induced Cytotoxicity through Activation of AMPK in Neuronal Cells.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; AMP-Activated Protein Kinases; Amyloid beta-Peptides; Ce | 2015 |
sAPPalpha antagonizes dendritic degeneration and neuron death triggered by proteasomal stress.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Ap | 2010 |
Berberine ameliorates β-amyloid pathology, gliosis, and cognitive impairment in an Alzheimer's disease transgenic mouse model.
Topics: ADAM Proteins; ADAM10 Protein; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precur | 2012 |
P2X7 mediates superoxide production in primary microglia and is up-regulated in a transgenic mouse model of Alzheimer's disease.
Topics: Adenosine Triphosphate; Alzheimer Disease; Animals; Animals, Newborn; Calcium; Cerebral Cortex; Chro | 2003 |
Wild-type but not FAD mutant presenilin-1 prevents neuronal degeneration by promoting phosphatidylinositol 3-kinase neuroprotective signaling.
Topics: Alzheimer Disease; Animals; Apoptosis; Brain; Caspases; Cells, Cultured; Chromones; Down-Regulation; | 2008 |
Estrogen protects against beta-amyloid-induced neurotoxicity in rat hippocampal neurons by activation of Akt.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Count; Cell Survival; Cells, Cultured; Chrom | 2001 |