2-(4-(2-carboxyethyl)phenethylamino)-5--n-ethylcarboxamidoadenosine and Lesch-Nyhan-Syndrome

2-(4-(2-carboxyethyl)phenethylamino)-5--n-ethylcarboxamidoadenosine has been researched along with Lesch-Nyhan-Syndrome* in 1 studies

Other Studies

1 other study(ies) available for 2-(4-(2-carboxyethyl)phenethylamino)-5--n-ethylcarboxamidoadenosine and Lesch-Nyhan-Syndrome

ArticleYear
Hypoxanthine effects on cyclic AMP levels in human lymphocytes.
    Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9

    We have measured hypoxanthine effect on cAMP levels in PBL in basal conditions (no agonist), and with the addition of 2-(p-[2-carboxyethyl] phenylethylamino)-5'-N-ethylcarboxamidoadenosine (CGS-21680, a specific A2 receptor agonist). We have found that hypoxanthine, at 25 microM and 50 microM concentrations, increases cAMP levels in PBL in basal and A2 agonist stimulated conditions.

    Topics: Adenosine; Antihypertensive Agents; Cyclic AMP; Enzyme-Linked Immunosorbent Assay; Humans; Hypoxanthine; Lesch-Nyhan Syndrome; Lymphocytes; Phenethylamines; Receptors, Adenosine A2; Receptors, Purinergic P1; Temperature; Time Factors

2004