2-(1h-benzotriazol-1-yl)-1-1-3-3-tetramethyluronium-hexafluorophosphate and Urticaria

2-(1h-benzotriazol-1-yl)-1-1-3-3-tetramethyluronium-hexafluorophosphate has been researched along with Urticaria* in 3 studies

Other Studies

3 other study(ies) available for 2-(1h-benzotriazol-1-yl)-1-1-3-3-tetramethyluronium-hexafluorophosphate and Urticaria

ArticleYear
Respiratory and skin hypersensitivity reactions caused by a peptide coupling reagent.
    Occupational and environmental medicine, 2008, Volume: 65, Issue:10

    Topics: Adult; Asthma; Dermatitis, Contact; Dermatitis, Occupational; Female; Humans; Male; Middle Aged; Respiratory Hypersensitivity; Rhinitis; Triazoles; Urea; Urticaria; Young Adult

2008
Anaphylaxis and allergic contact urticaria from occupational airborne exposure to HBTU.
    Occupational medicine (Oxford, England), 2006, Volume: 56, Issue:6

    We describe a case of anaphylaxis and allergic contact urticaria from occupational airborne exposure to HBTU (o-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate), which is a chemical used widely for solid and solution-phase peptide synthesis. Previously, the use of this chemical has been associated with occupational asthma, allergic contact urticaria and allergic contact dermatitis in individual cases, but not with anaphylaxis. Our diagnoses were based on the clinical symptoms, positive skin prick test (SPT) and positive skin provocation test to HBTU. The positive SPT indicates that the anaphylaxis reaction was IgE-mediated. We recommend that in the handling of HBTU, appropriate safety measures should be compulsory, and if work-related symptoms develop, the possibility of anaphylaxis should be considered in advising on appropriate work tasks.

    Topics: Adult; Air Pollutants, Occupational; Anaphylaxis; Dermatitis, Allergic Contact; Dermatitis, Occupational; Epinephrine; Epoxy Resins; Histamine H1 Antagonists; Humans; Laboratory Chemicals; Male; Medical Laboratory Personnel; Triazoles; Urea; Urticaria

2006
Occupational contact urticaria from the solid-phase peptide synthesis coupling agents HATU and HBTU.
    Contact dermatitis, 2003, Volume: 49, Issue:2

    Topics: Adult; Dermatitis, Occupational; Female; Humans; Pyridines; Skin Tests; Triazoles; Urea; Urticaria

2003