2-(1-(2-(1-methylpyrrolidino)ethyl)-1h-indol-3-yl)maleimide has been researched along with Pheochromocytoma in 1 studies
bisindolylmaleimide II: protein kinase C inhibitor; see also bisindolylmaleimide I
Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mahata, M | 1 |
| Mahapatra, NR | 1 |
| O'Connor, DT | 1 |
| Mahata, SK | 1 |
1 other study available for 2-(1-(2-(1-methylpyrrolidino)ethyl)-1h-indol-3-yl)maleimide and Pheochromocytoma
| Article | Year |
|---|---|
Chromaffin cell catecholamine secretion: bisindolylmaleimide compounds exhibit novel and potent antagonist effects at the nicotinic cholinergic receptor in pheochromocytoma cells.
Topics: Animals; Binding, Competitive; Catecholamines; Chromaffin Cells; Enzyme Activation; Enzyme Inhibitor | 2002 |