1h-indene-2-carboxylic acid, 1-(1,3-benzodioxol-5-yl)-3-(2- (carboxymethoxy)-4-methoxyphenyl)-2,3-dihydro-5-propoxy-, (1s,2r,3s)- has been researched along with Blood Pressure, High in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (47.37) | 18.2507 |
| 2000's | 10 (52.63) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| D'Amico, M; Di Filippo, C; Filippelli, A; Piegari, E; Rinaldi, B; Rossi, F | 1 |
| Goddard, J; Webb, DJ | 1 |
| Hattori, Y; Jesmin, S; Kitabatake, A; Miyauchi, T; Sakuma, I; Togashi, H; Yoshioka, M | 3 |
| Goto, K; Jesmin, S; Maeda, S; Miyauchi, T; Togashi, H; Yamaguchi, I; Zaedi, S | 1 |
| Jesmin, S; Kato, N; Maeda, S; Miyauchi, T; Mowa, CN; Prodhan, SH; Sakuma, I; Togashi, H; Yamaguchi, T; Yoshioka, M; Zaedi, S | 1 |
| Douglas, SA; Elliott, JD; Ezekiel, M; Feuerstein, GZ; Gellai, M; Ohlstein, EH | 1 |
| Bennett, T; Gardiner, SM; Kemp, PA; March, JE; Mullins, JJ | 1 |
| Bennett, T; Gardiner, SM; Kemp, PA; March, JE | 4 |
| Granger, J; Kassab, S; Kirchner, K; Miller, T; Novak, J | 1 |
| Fukamizu, A; Goto, K; Kobayashi, T; Maeda, S; Maki, S; Miyauchi, T; Murakami, K; Sakai, S; Sugishita, Y; Sugiyama, F; Takata, Y | 1 |
| Bunting, MW; Widdop, RE | 1 |
| Bennett, T; Gardiner, SM | 1 |
| Berthiaume, N; D'Orléans-Juste, P; Labonté, J; Yanagisawa, M | 1 |
| Krum, H; Martin, P; Ninio, D | 1 |
1 trial(s) available for 1h-indene-2-carboxylic acid, 1-(1,3-benzodioxol-5-yl)-3-(2- (carboxymethoxy)-4-methoxyphenyl)-2,3-dihydro-5-propoxy-, (1s,2r,3s)- and Blood Pressure, High
| Article | Year |
|---|---|
Effect of endothelin blockade on basal and stimulated forearm blood flow in patients with essential hypertension.
Topics: Blood Flow Velocity; Blood Pressure; Endothelin Receptor Antagonists; Female; Forearm; Heart Rate; Humans; Hypertension; Indans; Infusions, Intra-Arterial; Male; Middle Aged; Time Factors | 2002 |
18 other study(ies) available for 1h-indene-2-carboxylic acid, 1-(1,3-benzodioxol-5-yl)-3-(2- (carboxymethoxy)-4-methoxyphenyl)-2,3-dihydro-5-propoxy-, (1s,2r,3s)- and Blood Pressure, High
| Article | Year |
|---|---|
Local administration of ETA (but not ETB) blockers into the PAG area of the brain decreases blood pressure of DOCA-salt rats.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Azepines; Blood Pressure; Desoxycorticosterone; Electrophoresis, Agar Gel; Endothelin Receptor Antagonists; Endothelin-1; Glyceraldehyde-3-Phosphate Dehydrogenases; Heart Rate; Hypertension; Indans; Indoles; Male; Oligopeptides; Periaqueductal Gray; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2002 |
Endothelin antagonists and hypertension: a question of dose?
Topics: Endothelin Receptor Antagonists; Forearm; Humans; Hypertension; Indans; Infusions, Intra-Arterial; Peptides, Cyclic; Regional Blood Flow; Vasodilation | 2002 |
Expression of endothelin receptors in the brain of SHR-SP and effects of an endothelin blocker.
Topics: Age Factors; Animals; Antihypertensive Agents; Cerebral Cortex; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Hypertension; Indans; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Endothelin A; Receptor, Endothelin B; Stroke | 2004 |
Brain expression of VEGF and its receptors in SHR-SP and effects of an endothelin blocker.
Topics: Age Factors; Animals; Antihypertensive Agents; Cerebral Cortex; Disease Models, Animal; Endothelin Receptor Antagonists; Hypertension; Indans; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Endothelin; Stroke; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2004 |
Effects of endothelin receptor antagonist on expression of AT1 and AT2 receptors in the heart of SHR-SP.
Topics: Angiotensin II; Animals; Coronary Vessels; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Hypertension; Indans; Male; Myocardium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Endothelin A; Receptor, Endothelin B; Signal Transduction; Stroke | 2004 |
Endothelin antagonism suppresses plasma and cardiac endothelin-1 levels in SHRSPs at the typical hypertensive stage.
Topics: Animals; Antihypertensive Agents; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Heart Ventricles; Hypertension; Indans; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2006 |
Antagonism of endothelin action normalizes altered levels of VEGF and its signaling in the brain of stroke-prone spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Brain; Cerebrovascular Circulation; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Indans; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Endothelin; Signal Transduction; Stroke; Vascular Endothelial Growth Factor A | 2007 |
Antihypertensive actions of the novel nonpeptide endothelin receptor antagonist SB 209670.
Topics: Animals; Antihypertensive Agents; Dose-Response Relationship, Drug; Duodenum; Electric Stimulation; Endothelin Receptor Antagonists; Heart Rate; Hypertension; Indans; Injections; Injections, Intravenous; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Renin; Sympathetic Nervous System | 1995 |
Haemodynamic effects of losartan and the endothelin antagonist, SB 209670, in conscious, transgenic ((mRen-2)27), hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Biphenyl Compounds; Endothelin Receptor Antagonists; Endothelins; Hemodynamics; Hypertension; Imidazoles; Indans; Losartan; Male; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Regional Blood Flow; Tetrazoles | 1995 |
Regional haemodynamic effects of antagonists of angiotensin II, endothelin and adrenoceptors in conscious, vasopressin-deficient, genetically hypertensive rats.
Topics: Adrenergic Antagonists; Angiotensin II; Animals; Biphenyl Compounds; Endothelins; Hemodynamics; Hypertension; Imidazoles; Indans; Losartan; Male; Rats; Sodium Chloride; Tetrazoles; Vasopressins | 1996 |
Role of endothelin in mediating the attenuated renal hemodynamics in Dahl salt-sensitive hypertension.
Topics: Animals; Endothelins; Hemodynamics; Hypertension; Indans; Kidney; Male; Rats; Rats, Sprague-Dawley; Sodium, Dietary | 1997 |
Enhanced involvement of endothelin in the haemodynamic sequelae of endotoxaemia in conscious, hypertensive, transgenic ((mRen-2)27) rats.
Topics: Animals; Animals, Genetically Modified; Blood Pressure; Endothelin Receptor Antagonists; Endothelins; Endotoxemia; Hemodynamics; Hypertension; Indans; Lipopolysaccharides; Male; Rats; Rats, Sprague-Dawley | 1998 |
Endothelin-1 expression in hearts of transgenic hypertensive mice overexpressing angiotensin II.
Topics: Angiotensin II; Animals; Cardiomegaly; Disease Progression; Endothelin Receptor Antagonists; Endothelin-1; Hemodynamics; Humans; Hypertension; Indans; Male; Mice; Mice, Transgenic; Myocardium; Polymerase Chain Reaction; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger | 1998 |
Differential haemodynamic effects of endothelin receptor antagonist, SB 209670, in conscious hypertensive and normotensive rats.
Topics: Animals; Blood Pressure; Consciousness; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Heart Rate; Hemodynamics; Hindlimb; Hypertension; Indans; Infusions, Intravenous; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Regional Blood Flow; Renal Circulation; Splanchnic Circulation; Vasoconstriction | 1999 |
Cardiovascular responses to angiotensins I and II in normotensive and hypertensive rats; effects of NO synthase inhibition or ET receptor antagonism.
Topics: Angiotensin I; Angiotensin II; Animals; Endothelin Receptor Antagonists; Enzyme Inhibitors; Hemodynamics; Hypertension; Indans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Vasoconstrictor Agents | 1999 |
Comment on "Interactions between endothelin-1 and the renin-angiotensin-aldosterone system".
Topics: Aldosterone; Animals; Animals, Genetically Modified; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Indans; Male; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System | 1999 |
Heterozygous knock-Out of ET(B) receptors induces BQ-123-sensitive hypertension in the mouse.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Drug Interactions; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Female; Heterozygote; Hypertension; Indans; Iodine Radioisotopes; Male; Metabolic Clearance Rate; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; Oligopeptides; Peptide Fragments; Peptides, Cyclic; Piperidines; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin | 2000 |
Cardiovascular effects of endothelin-1 and endothelin antagonists in conscious, hypertensive ((mRen-2)27) rats.
Topics: Anesthetics; Animals; Animals, Genetically Modified; Baroreflex; Blood Pressure; Butyrophenones; Cardiovascular Agents; Consciousness; Dioxoles; Dose-Response Relationship, Drug; Drug Combinations; Endothelin Receptor Antagonists; Endothelin-1; Female; Fentanyl; Heart; Heart Rate; Humans; Hypertension; Indans; Male; Medetomidine; Methohexital; Mice; Midazolam; Pyrazoles; Rats; Rats, Sprague-Dawley; Renin; Time Factors | 2000 |