1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one has been researched along with Pregnancy in 14 studies
1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one: structure given in first source; inhibits guanylyl cyclase
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one : A member of the class of oxadiazoloquinoxalines that is 1H-[1,2,4]oxadiazolo[4,3-a]quinoxaline substituted at position 1 by an oxo group.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eighteen pregnant women with preeclampsia and 18 healthy pregnant women were involved." | 1.38 | Endothelial dysfunction in the human umbilical artery due to preeclampsia can be prevented by sildenafil. ( Dinc, B; Karasu, E; Kayacan, N; Sadan, G, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (78.57) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pearce, WJ | 1 |
| Williams, JM | 1 |
| White, CR | 1 |
| Lincoln, TM | 1 |
| Chester, M | 2 |
| Tourneux, P | 2 |
| Seedorf, G | 2 |
| Grover, TR | 1 |
| Gien, J | 2 |
| Abman, SH | 2 |
| Buxton, IL | 2 |
| Milton, D | 1 |
| Barnett, SD | 1 |
| Tichenor, SD | 1 |
| Tseng, N | 1 |
| Grover, T | 1 |
| Wright, J | 1 |
| Stasch, JP | 1 |
| Karasu, E | 1 |
| Kayacan, N | 1 |
| Sadan, G | 1 |
| Dinc, B | 1 |
| Longo, M | 1 |
| Jain, V | 1 |
| Vedernikov, YP | 1 |
| Garfield, RE | 1 |
| Saade, GR | 1 |
| Orshal, JM | 1 |
| Khalil, RA | 3 |
| Gandley, RE | 1 |
| Tyurin, VA | 1 |
| Huang, W | 1 |
| Arroyo, A | 1 |
| Daftary, A | 1 |
| Harger, G | 1 |
| Jiang, J | 1 |
| Pitt, B | 1 |
| Taylor, RN | 1 |
| Hubel, CA | 1 |
| Kagan, VE | 1 |
| Tiritilli, A | 1 |
| Teunissen, CE | 1 |
| Steinbusch, HW | 1 |
| Axer, H | 1 |
| Ingram, JN | 1 |
| Renfree, MB | 1 |
| Shaw, G | 1 |
| Kaiser, RA | 1 |
| Malmquist, NA | 1 |
| Tichenor, S | 1 |
| Barron, LA | 1 |
| Giardina, JB | 2 |
| Granger, JP | 2 |
| Davis, JR | 1 |
| Green, GM | 1 |
| Alexander, BT | 1 |
14 other studies available for 1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and Pregnancy
| Article | Year |
|---|---|
Effects of chronic hypoxia on soluble guanylate cyclase activity in fetal and adult ovine cerebral arteries.
Topics: Altitude Sickness; Animals; Cerebral Arteries; Chronic Disease; Cyclic GMP; Cyclic GMP-Dependent Pro | 2009 |
Cinaciguat, a soluble guanylate cyclase activator, causes potent and sustained pulmonary vasodilation in the ovine fetus.
Topics: Acetylcholine; Animals; Animals, Newborn; Benzoates; Cells, Cultured; Cyclic GMP; Dose-Response Rela | 2009 |
Agonist-specific compartmentation of cGMP action in myometrium.
Topics: Animals; Blotting, Western; Caveolin 1; Cell Membrane; Cyclic GMP; Enzyme Inhibitors; Estrogens; Fem | 2010 |
Cinaciguat, a soluble guanylate cyclase activator, augments cGMP after oxidative stress and causes pulmonary vasodilation in neonatal pulmonary hypertension.
Topics: Animals; Benzoates; Cells, Cultured; Cyclic GMP; Disease Models, Animal; Female; Fetus; Guanylate Cy | 2011 |
Endothelial dysfunction in the human umbilical artery due to preeclampsia can be prevented by sildenafil.
Topics: Adolescent; Adult; Case-Control Studies; Endothelium, Vascular; Enzyme Inhibitors; Female; Guanylate | 2012 |
Effects of recombinant human relaxin on pregnant rat uterine artery and myometrium in vitro.
Topics: Adenine; Animals; Arteries; Dose-Response Relationship, Drug; Female; Gestational Age; Humans; Myome | 2003 |
Interleukin-6 impairs endothelium-dependent NO-cGMP-mediated relaxation and enhances contraction in systemic vessels of pregnant rats.
Topics: Acetylcholine; Animals; Blotting, Western; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Est | 2004 |
S-nitrosoalbumin-mediated relaxation is enhanced by ascorbate and copper: effects in pregnancy and preeclampsia plasma.
Topics: Adult; Animals; Ascorbic Acid; Copper; Female; Humans; Mesenteric Arteries; Mice; NG-Nitroarginine M | 2005 |
Guanylate cyclase and not ATP-dependent K(+) channels seems temperature-dependent in smooth muscle relaxation of human umbilical arteries.
Topics: Adenosine Triphosphate; Arginine; Cromakalim; Dose-Response Relationship, Drug; Female; Glyburide; G | 2000 |
Whole brain spheroid cultures as a model to study the development of nitric oxide synthase-guanylate cyclase signal transduction.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Astrocytes; Atrial Natriuretic Factor; Brain; Cell Culture Tec | 2000 |
Differential regulation of contractility and nitric oxide sensitivity in gravid and nongravid myometrium during late pregnancy in a marsupial.
Topics: Animals; Cyclic GMP; Enzyme Inhibitors; Female; Gestational Age; Guanylate Cyclase; Kinetics; Marsup | 2001 |
NO-induced relaxation of labouring and non-labouring human myometrium is not mediated by cyclic GMP.
Topics: Charybdotoxin; Cyclic GMP; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gu | 2001 |
High-salt diet enhances vascular reactivity in pregnant rats with normal and reduced uterine perfusion pressure.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Pressure; Dose-Response Relationship, Drug; Endotheli | 2001 |
Reduced endothelial NO-cGMP vascular relaxation pathway during TNF-alpha-induced hypertension in pregnant rats.
Topics: Acetylcholine; Animals; Antineoplastic Agents; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; | 2002 |