1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one has been researched along with Osteoarthritis in 1 studies
1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one: structure given in first source; inhibits guanylyl cyclase
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one : A member of the class of oxadiazoloquinoxalines that is 1H-[1,2,4]oxadiazolo[4,3-a]quinoxaline substituted at position 1 by an oxo group.
Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tadalafil dose-dependently inhibited hypernociception in zymosan and osteoarthritis models." | 3.77 | Tadalafil analgesia in experimental arthritis involves suppression of intra-articular TNF release. ( Castro, RR; Cunha, FQ; Girão, VC; Leite, AC; Leite, AK; Rocha, FA; Silva, FS, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rocha, FA | 1 |
| Silva, FS | 1 |
| Leite, AC | 1 |
| Leite, AK | 1 |
| Girão, VC | 1 |
| Castro, RR | 1 |
| Cunha, FQ | 1 |
1 other study available for 1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and Osteoarthritis
| Article | Year |
|---|---|
Tadalafil analgesia in experimental arthritis involves suppression of intra-articular TNF release.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthralgia; Arthritis, Experimental; Carbolines; Chem | 2011 |