1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one has been researched along with Myocardial Ischemia in 3 studies
1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one: structure given in first source; inhibits guanylyl cyclase
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one : A member of the class of oxadiazoloquinoxalines that is 1H-[1,2,4]oxadiazolo[4,3-a]quinoxaline substituted at position 1 by an oxo group.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this study was to investigate the effect of L-arginine supplementation on myocardial cell death secondary to hypoxia-reoxygenation." | 7.70 | L-arginine limits myocardial cell death secondary to hypoxia-reoxygenation by a cGMP-dependent mechanism. ( Agulló, L; García-Dorado, D; Inserte, J; Llevadot, J; Paniagua, A; Pyrhonen, P; Soler-Soler, J, 1999) |
| "The objective of this study was to investigate the effect of L-arginine supplementation on myocardial cell death secondary to hypoxia-reoxygenation." | 3.70 | L-arginine limits myocardial cell death secondary to hypoxia-reoxygenation by a cGMP-dependent mechanism. ( Agulló, L; García-Dorado, D; Inserte, J; Llevadot, J; Paniagua, A; Pyrhonen, P; Soler-Soler, J, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Agulló, L | 1 |
| García-Dorado, D | 1 |
| Inserte, J | 1 |
| Paniagua, A | 1 |
| Pyrhonen, P | 1 |
| Llevadot, J | 1 |
| Soler-Soler, J | 1 |
| Rakhit, RD | 1 |
| Edwards, RJ | 1 |
| Mockridge, JW | 1 |
| Baydoun, AR | 1 |
| Wyatt, AW | 1 |
| Mann, GE | 1 |
| Marber, MS | 1 |
| Lochner, A | 1 |
| Marais, E | 1 |
| Genade, S | 1 |
| Moolman, JA | 1 |
3 other studies available for 1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and Myocardial Ischemia
| Article | Year |
|---|---|
L-arginine limits myocardial cell death secondary to hypoxia-reoxygenation by a cGMP-dependent mechanism.
Topics: Animals; Arginine; Cell Death; Cells, Cultured; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Hy | 1999 |
Nitric oxide-induced cardioprotection in cultured rat ventricular myocytes.
Topics: Alkaloids; Animals; Animals, Newborn; Anti-Infective Agents; Benzophenanthridines; Cells, Cultured; | 2000 |
Nitric oxide: a trigger for classic preconditioning?
Topics: Adenosine Monophosphate; Animals; Cyclic GMP; Enzyme Inhibitors; Epinephrine; Guanylate Cyclase; In | 2000 |