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1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and Muscle Contraction

1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one has been researched along with Muscle Contraction in 58 studies

1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one: structure given in first source; inhibits guanylyl cyclase
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one : A member of the class of oxadiazoloquinoxalines that is 1H-[1,2,4]oxadiazolo[4,3-a]quinoxaline substituted at position 1 by an oxo group.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
" In thoracic aortic rings from CH rats, cumulative dose-response curves to phenylephrine (PE) in the presence of the nitric oxide (NO) synthase inhibitor Nomega-nitro-L-arginine (L-NNA) and the HO inhibitor zinc protoporphyrin 9 (ZnPPIX) elicited increased contractility compared with CH rings treated with only L-NNA."5.30Role of endothelial carbon monoxide in attenuated vasoreactivity following chronic hypoxia. ( Caudill, TK; Kanagy, NL; Resta, TC; Walker, BR, 1998)
" We have previously demonstrated that mesenteric lymphatic pumping was compromised in the guinea pig model of 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced ileitis, corroborating clinical and experimental observations of a dilated and/or obstructed phenotype of these vessels in inflammatory bowel disease."3.79Involvement of the NO-cGMP-K(ATP) channel pathway in the mesenteric lymphatic pump dysfunction observed in the guinea pig model of TNBS-induced ileitis. ( Mathias, R; von der Weid, PY, 2013)
" Caffeine and ryanodine contractions were augmented during endotoxemia without NOS contribution."3.72The role of nitric oxide on contractile impairment during endotoxemia in rat diaphragm muscle. ( Ertunc, M; Onur, R; Sara, Y, 2004)
" The first part consisted of a tetanic striated muscle contraction, which was abolished by tubocurarin (10(-5) M) but unaffected by atropine (10(-6) M) or hexamethonium (10(-4) M)."3.71Characterization of vagal input to the rat esophageal muscle. ( Allescher, HD; Geisler, F; Neuhuber, WL; Schusdziarra, V; Storr, M, 2001)
"Indomethacin was used to evaluate the influence of prostanoids on the RCs."1.34Endothelial nitric oxide has inhibitory effects on rhythmic contractions in the aortas of sinoaortic deafferented rats. ( Bendhack, LM; Rocha, ML, 2007)
" In thoracic aortic rings from CH rats, cumulative dose-response curves to phenylephrine (PE) in the presence of the nitric oxide (NO) synthase inhibitor Nomega-nitro-L-arginine (L-NNA) and the HO inhibitor zinc protoporphyrin 9 (ZnPPIX) elicited increased contractility compared with CH rings treated with only L-NNA."1.30Role of endothelial carbon monoxide in attenuated vasoreactivity following chronic hypoxia. ( Caudill, TK; Kanagy, NL; Resta, TC; Walker, BR, 1998)

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's15 (25.86)18.2507
2000's36 (62.07)29.6817
2010's7 (12.07)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Szadujkis-Szadurska, K1
Grzesk, G1
Szadujkis-Szadurski, L1
Gajdus, M1
Malinowski, B1
Wicinski, M1
Gasheva, OY1
Gashev, AA1
Zawieja, DC1
Gur, S1
Sikka, SC1
Abdel-Mageed, AB1
Abd Elmageed, ZY1
Rezk, B1
Pankey, E1
Kadowitz, PJ1
Hellstrom, WJ1
Shimbo, T1
Adachi, T1
Fujisawa, S1
Hongoh, M1
Ohba, T1
Ono, K1
Toque, HA2
Priviero, FB3
Zemse, SM1
Antunes, E4
Teixeira, CE3
Webb, RC3
Han, WQ1
Zhu, DL1
Wu, LY1
Chen, QZ1
Guo, SJ1
Gao, PJ1
Mónica, FZ1
Morganti, RP1
De Nucci, G3
Pires, AL1
Pinho, M1
Sena, CM1
Seica, R1
Leite-Moreira, AF1
Mathias, R1
von der Weid, PY1
Hsieh, GC2
O'Neill, AB1
Moreland, RB1
Sullivan, JP2
Brioni, JD2
Chen, SJ2
Chen, KH1
Yen, MH2
Wu, CC2
Miyamoto, A1
Yamazaki, Y1
Takagi, T1
Ishiguro, S1
Nishio, A1
Williams, M1
Kerkar, S1
Tyburski, JG1
Steffes, CP1
Carlin, AM1
Wilson, RF1
de Oliveira, JF1
Baracat, JS2
Okuyama, CE1
Rodrigues Netto, N1
Fregonesi, A1
Shelkovnikov, S1
Merlic, CA1
Gonick, HC1
Orshal, JM1
Khalil, RA1
Ueno, T1
Duenes, JA1
Zarroug, AE1
Sarr, MG1
Sendão Oliveira, AP1
Bendhack, LM2
Wang, C1
Mansard, A1
Giummelly, P1
Atkinson, J1
Sara, Y1
Ertunc, M1
Onur, R1
Ekerhovd, E1
Norström, A1
Bawankule, DU1
Sathishkumar, K1
Sardar, KK1
Chanda, D1
Krishna, AV1
Prakash, VR1
Mishra, SK1
Chung, SS1
Ahn, DS1
Lee, HG1
Lee, YH1
Nam, TS1
Amato, A1
Corti, A1
Serio, R2
Mulè, F2
Anctil, M1
Poulain, I1
Pelletier, C1
Elmedal, B1
Mulvany, MJ1
Simonsen, U1
Uchikawa, Y1
Okano, M1
Sawada, A1
Asada, Y1
Kobayashi, H1
Wada, A1
Nao-i, N1
Ohkura, M1
Tanaka, N1
Yamamoto, R1
Claudino, MA1
Di Pascoli, M1
Rodella, L1
Sacerdoti, D1
Bolognesi, M1
Turkseven, S1
Abraham, NG1
Rocha, ML1
Cellek, S1
Moncada, S1
Franck, H1
Sweeney, KM1
Sanders, KM1
Shuttleworth, CW1
Li, PL1
Jin, MW1
Campbell, WB1
Hebeiss, K1
Kilbinger, H1
Canning, BJ1
Fischer, A1
Olgart, C1
Hallén, K1
Wiklund, NP1
Iversen, HH1
Gustafsson, LE1
Recio, P1
López, PG1
Hernández, M1
Prieto, D1
Contreras, J1
García-Sacristán, A1
Lefebvre, RA1
Caudill, TK1
Resta, TC1
Kanagy, NL1
Walker, BR1
Di Stilo, A1
Visentin, S1
Cena, C1
Gasco, AM1
Ermondi, G1
Gasco, A1
Galle, J1
Zabel, U1
Hübner, U1
Hatzelmann, A1
Wagner, B1
Wanner, C1
Schmidt, HH1
D'Angelo, S1
Silva, HM1
Ambiel, CR1
Alves-Do-Prado, W1
Koshita, M1
Takano, H1
Nakahira, Y1
Suzuki, H1
Garcia-Pascual, A1
Labadia, A1
Costa, G1
Triguero, D1
Mundey, MK1
Jonas, M1
Worthley, T1
Scholefield, JH1
Wilson, VG1
Shahin, W1
Murray, JA1
Clark, E1
Conklin, JL1
Baccari, MC1
Calamai, F1
Hennan, JK1
Diamond, J1
Oğülener, N1
Ergün, Y1
Döndaş, N1
Dikmen, A1
Gonzalez, A1
Sarna, SK1
Kolasa, T1
Tanović, A1
Jiménez, M1
Fernández, E1
Storr, M1
Geisler, F1
Neuhuber, WL1
Schusdziarra, V1
Allescher, HD1
Komuro, T1
Borsody, MK1
Ono, S1
Marton, LS1
Weir, BK1
Zhang, ZD1
Paik, E1
Macdonald, RL1
Takeuch, T1
Sugimoto, K1
Morimoto, H1
Fujita, A1
Hata, F1
Devillier, P1
Corompt, E1
Bréant, D1
Caron, F1
Bessard, G1

Other Studies

58 other studies available for 1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and Muscle Contraction

ArticleYear
Role of endothelium, acetylocholine and calcium ions in Bay K8644- and KCl-induced contraction.
    Molecular medicine reports, 2013, Volume: 8, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2013
Cyclic guanosine monophosphate and the dependent protein kinase regulate lymphatic contractility in rat thoracic duct.
    The Journal of physiology, 2013, Sep-15, Volume: 591, Issue:18

    Topics: Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Guanylate Cyclase; Isoenzymes; Lymphatic

2013
Imatinib mesylate (Gleevec) induces human corpus cavernosum relaxation by inhibiting receptor tyrosine kinases (RTKs): identification of new RTK targets.
    Urology, 2013, Volume: 82, Issue:3

    Topics: Adult; Aged; Apamin; Benzamides; Enzyme Activation; Erectile Dysfunction; Humans; Imatinib Mesylate;

2013
In vitro effect of nicorandil on the carbachol-induced contraction of the lower esophageal sphincter of the rat.
    Journal of pharmacological sciences, 2016, Volume: 131, Issue:4

    Topics: Animals; Carbachol; Diazoxide; Dose-Response Relationship, Drug; Esophageal Sphincter, Lower; Glybur

2016
Effect of the phosphodiesterase 5 inhibitors sildenafil, tadalafil and vardenafil on rat anococcygeus muscle: functional and biochemical aspects.
    Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:4

    Topics: Animals; Carbolines; Drug Evaluation, Preclinical; Enzyme Inhibitors; Guanylate Cyclase; Imidazoles;

2009
N-acetylcysteine-induced vasodilation involves voltage-gated potassium channels in rat aorta.
    Life sciences, 2009, May-22, Volume: 84, Issue:21-22

    Topics: Acetylcysteine; Animals; Calcium; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Guanylate Cyclas

2009
Mechanisms of relaxant activity of the nitric oxide-independent soluble guanylyl cyclase stimulator BAY 41-2272 in rat tracheal smooth muscle.
    European journal of pharmacology, 2010, Oct-25, Volume: 645, Issue:1-3

    Topics: Animals; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Activation; Enzy

2010
Intermedin elicits a negative inotropic effect in rat papillary muscles mediated by endothelial-derived nitric oxide.
    American journal of physiology. Heart and circulatory physiology, 2012, Mar-01, Volume: 302, Issue:5

    Topics: Adrenomedullin; Animals; Calcitonin Gene-Related Peptide; Endothelium, Vascular; Enzyme Inhibitors;

2012
Involvement of the NO-cGMP-K(ATP) channel pathway in the mesenteric lymphatic pump dysfunction observed in the guinea pig model of TNBS-induced ileitis.
    American journal of physiology. Gastrointestinal and liver physiology, 2013, Mar-15, Volume: 304, Issue:6

    Topics: Animals; ATP-Binding Cassette Transporters; Disease Models, Animal; Enzyme Inhibitors; Glyburide; Gu

2013
YC-1 potentiates the nitric oxide/cyclic GMP pathway in corpus cavernosum and facilitates penile erection in rats.
    European journal of pharmacology, 2003, Jan-01, Volume: 458, Issue:1-2

    Topics: Animals; Cells, Cultured; Cyclic GMP; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhib

2003
Abnormal activation of Na+-K+ pump in aortas from rats with endotoxaemia.
    Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 368, Issue:1

    Topics: Animals; Aorta, Thoracic; Endotoxemia; Enzyme Inhibitors; Escherichia coli; In Vitro Techniques; Lip

2003
Enhancement of endotoxin-induced vascular hyporeactivity to phenylephrine in the thoracic aortas of Mg-deficient rats ex vivo.
    Life sciences, 2003, Oct-10, Volume: 73, Issue:21

    Topics: Amidines; Animals; Aorta, Thoracic; Benzylamines; Diet; Dose-Response Relationship, Drug; Enzyme Inh

2003
The roles of cyclic adenosine monophosphate- and cyclic guanosine monophosphate-dependent protein kinase pathways in hydrogen peroxide-induced contractility of microvascular lung pericytes.
    The Journal of trauma, 2003, Volume: 55, Issue:4

    Topics: Adenine; Adenylyl Cyclase Inhibitors; Analysis of Variance; Animals; Cell Survival; Cells, Cultured;

2003
Nitric oxide release from human corpus cavernosum induced by a purified scorpion toxin.
    Urology, 2004, Volume: 63, Issue:1

    Topics: Adolescent; Adult; Child; Cyclic GMP; Drug Evaluation, Preclinical; Electric Stimulation; Enzyme Inh

2004
Influence of nitric oxide donors and peroxynitrite on the contractile effect and concentration of norepinephrine.
    Life sciences, 2004, Apr-23, Volume: 74, Issue:23

    Topics: Animals; Aorta, Thoracic; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Dr

2004
Interleukin-6 impairs endothelium-dependent NO-cGMP-mediated relaxation and enhances contraction in systemic vessels of pregnant rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2004, Volume: 286, Issue:6

    Topics: Acetylcholine; Animals; Blotting, Western; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Est

2004
Nitrergic mechanisms mediating inhibitory control of longitudinal smooth muscle contraction in mouse small intestine.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2004, Volume: 8, Issue:7

    Topics: Animals; Atropine; Electric Stimulation; Enzyme Inhibitors; Gastrointestinal Motility; Guanylate Cyc

2004
Relaxation induced by acetylcholine involves endothelium-derived hyperpolarizing factor in 2-kidney 1-clip hypertensive rat carotid arteries.
    Pharmacology, 2004, Volume: 72, Issue:4

    Topics: Acetylcholine; Animals; Biological Factors; Carotid Arteries; Cyclic GMP; Cyclooxygenase Inhibitors;

2004
Decreased aortic smooth muscle contraction in a rat model of multibacterial sepsis.
    Fundamental & clinical pharmacology, 2004, Volume: 18, Issue:6

    Topics: Animals; Aorta; Disease Models, Animal; Endothelial Cells; Enzyme Inhibitors; Guanylate Cyclase; In

2004
The role of nitric oxide on contractile impairment during endotoxemia in rat diaphragm muscle.
    European journal of pharmacology, 2004, Nov-28, Volume: 505, Issue:1-3

    Topics: Animals; Caffeine; Diaphragm; Endotoxemia; Enzyme Inhibitors; Guanidines; In Vitro Techniques; Indaz

2004
Involvement of a nitric oxide-cyclic guanosine monophosphate pathway in control of fallopian tube contractility.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2004, Volume: 19, Issue:5

    Topics: Adult; Cyclic GMP; Enzyme Inhibitors; Fallopian Tubes; Female; Guanylate Cyclase; Humans; In Vitro T

2004
BAY 41-2272 [5-cyclopropyl-2-[1-(2-fluoro-benzyl)-1H-pyrazolo[3,4-b]pyridine-3-yl]pyrimidin-4-ylamine]-induced dilation in ovine pulmonary artery: role of sodium pump.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:1

    Topics: Animals; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dos

2005
Inhibition of carbachol-evoked oscillatory currents by the NO donor sodium nitroprusside in guinea-pig ileal myocytes.
    Experimental physiology, 2005, Volume: 90, Issue:4

    Topics: Animals; Caffeine; Carbachol; Chelating Agents; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Eg

2005
Inhibitory influence of chromogranin A N-terminal fragment (vasostatin-1) on the spontaneous contractions of rat proximal colon.
    Regulatory peptides, 2005, Aug-15, Volume: 130, Issue:1-2

    Topics: Animals; Apamin; Calreticulin; Chromogranin A; Chromogranins; Colon; Dose-Response Relationship, Dru

2005
Nitric oxide modulates peristaltic muscle activity associated with fluid circulation in the sea pansy Renilla koellikeri.
    The Journal of experimental biology, 2005, Volume: 208, Issue:Pt 10

    Topics: Animals; Anthozoa; Body Fluids; California; Guanidines; Immunohistochemistry; Indazoles; Muscle Cont

2005
Dual impact of a nitric oxide donor, GEA 3175, in human pulmonary smooth muscle.
    European journal of pharmacology, 2005, May-23, Volume: 516, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Albuterol; Bronchi; Bronchodilat

2005
Relaxant effect of adrenomedullin on bovine isolated iris sphincter muscle under resting conditions.
    Clinical and experimental pharmacology & physiology, 2005, Volume: 32, Issue:8

    Topics: Adrenomedullin; Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor A

2005
Stimulation of soluble guanylyl cyclase by BAY 41-2272 relaxes anococcygeus muscle: interaction with nitric oxide.
    European journal of pharmacology, 2006, Jan-13, Volume: 530, Issue:1-2

    Topics: Animals; Carbachol; Carbolines; Colforsin; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug;

2006
Chronic CO levels have [corrected] a beneficial effect on vascular relaxation in diabetes.
    Biochemical and biophysical research communications, 2006, Feb-17, Volume: 340, Issue:3

    Topics: Acetylcholine; Animals; Aorta; Biliverdine; Blotting, Western; Carbon Monoxide; Chromium; Densitomet

2006
Endothelial nitric oxide has inhibitory effects on rhythmic contractions in the aortas of sinoaortic deafferented rats.
    Journal of cardiovascular pharmacology, 2007, Volume: 50, Issue:5

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Autonomic Denervation; Blood Pressure; Dose-Respo

2007
Nitrergic control of peripheral sympathetic responses in the human corpus cavernosum: a comparison with other species.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Jul-22, Volume: 94, Issue:15

    Topics: Animals; Electric Stimulation; Guanethidine; Humans; Male; Mice; Muscle Contraction; Muscle, Smooth;

1997
Effects of a novel guanylate cyclase inhibitor on nitric oxide-dependent inhibitory neurotransmission in canine proximal colon.
    British journal of pharmacology, 1997, Volume: 122, Issue:6

    Topics: Animals; Colon; Cyclic GMP; Dogs; Electric Stimulation; Enzyme Inhibitors; Female; Guanylate Cyclase

1997
Effect of selective inhibition of soluble guanylyl cyclase on the K(Ca) channel activity in coronary artery smooth muscle.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:1 Pt 2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Animals; Cattle; Coro

1998
Nitric oxide-sensitive guanylyl cyclase inhibits acetylcholine release and excitatory motor transmission in the guinea-pig ileum.
    Neuroscience, 1998, Volume: 82, Issue:2

    Topics: Acetylcholine; Animals; Depression, Chemical; Electric Stimulation; Enzyme Inhibitors; Female; Guany

1998
Localization of heme oxygenase-2 immunoreactivity to parasympathetic ganglia of human and guinea-pig airways.
    American journal of respiratory cell and molecular biology, 1998, Volume: 18, Issue:2

    Topics: Animals; Atropine; Carbon Monoxide; Cyclic GMP; Enzyme Inhibitors; Female; Ganglia, Parasympathetic;

1998
Blockade of nitrergic neuroeffector transmission in guinea-pig colon by a selective inhibitor of soluble guanylyl cyclase.
    Acta physiologica Scandinavica, 1998, Volume: 162, Issue:1

    Topics: Animals; Colon; Electrophysiology; Enzyme Inhibitors; Guanylate Cyclase; Guinea Pigs; In Vitro Techn

1998
Nitrergic relaxation of the horse corpus cavernosum. Role of cGMP.
    European journal of pharmacology, 1998, Jun-12, Volume: 351, Issue:1

    Topics: Adenosine Triphosphate; Animals; Calcium; Cyclic GMP; Electric Stimulation; Enzyme Inhibitors; Horse

1998
Influence of a selective guanylate cyclase inhibitor, and of the contraction level, on nitrergic relaxations in the gastric fundus.
    British journal of pharmacology, 1998, Volume: 124, Issue:7

    Topics: Animals; Chymotrypsin; Electric Stimulation; Enzyme Inhibitors; Gastric Fundus; Guanylate Cyclase; M

1998
Nitric oxide-independent activation of soluble guanylyl cyclase contributes to endotoxin shock in rats.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: Animals; Aorta; Blood Pressure; Charybdotoxin; Dexamethasone; Endothelium, Vascular; Enzyme Activati

1998
Role of endothelial carbon monoxide in attenuated vasoreactivity following chronic hypoxia.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: Animals; Aorta, Thoracic; Arsenites; Carbon Monoxide; Endothelium, Vascular; Enzyme Inhibitors; Guan

1998
New 1,4-dihydropyridines conjugated to furoxanyl moieties, endowed with both nitric oxide-like and calcium channel antagonist vasodilator activities.
    Journal of medicinal chemistry, 1998, Dec-31, Volume: 41, Issue:27

    Topics: Animals; Aorta, Thoracic; Binding, Competitive; Calcium Channel Blockers; Cerebral Cortex; Dihydropy

1998
Effects of the soluble guanylyl cyclase activator, YC-1, on vascular tone, cyclic GMP levels and phosphodiesterase activity.
    British journal of pharmacology, 1999, Volume: 127, Issue:1

    Topics: Animals; Aorta, Thoracic; Cyclic GMP; Enzyme Activation; Enzyme Inhibitors; Guanylate Cyclase; In Vi

1999
Tonic inhibitory action by nitric oxide on spontaneous mechanical activity in rat proximal colon: involvement of cyclic GMP and apamin-sensitive K+ channels.
    British journal of pharmacology, 1999, Volume: 127, Issue:2

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Colon; Cyclic

1999
The neuromuscular transmission fade (Wedensky inhibition) induced by L-arginine in neuromuscular preparations from rats.
    General pharmacology, 1999, Volume: 32, Issue:6

    Topics: Animals; Arginine; Diaphragm; Electric Stimulation; Enzyme Inhibitors; Female; In Vitro Techniques;

1999
Pranidipine enhances relaxation produced by endothelium-derived relaxing factor in carotid artery.
    European journal of pharmacology, 1999, Dec-03, Volume: 385, Issue:2-3

    Topics: Acetylcholine; Animals; Calcium Channel Blockers; Carotid Arteries; Dihydropyridines; Dose-Response

1999
Effects of superoxide anion generators and thiol modulators on nitrergic transmission and relaxation to exogenous nitric oxide in the sheep urethra.
    British journal of pharmacology, 2000, Volume: 129, Issue:1

    Topics: Animals; Ascorbate Oxidase; Benzoates; Ditiocarb; Electric Stimulation; Enzyme Inhibitors; Female; G

2000
Pharmacological characterization of neurogenic responses of the sheep isolated internal anal sphincter.
    British journal of pharmacology, 2000, Volume: 130, Issue:3

    Topics: Anal Canal; Animals; Autonomic Nervous System; Calcium; Cyclic GMP; Electric Stimulation; Enzyme Inh

2000
Role of cGMP as a mediator of nerve-induced motor functions of the opossum esophagus.
    American journal of physiology. Gastrointestinal and liver physiology, 2000, Volume: 279, Issue:3

    Topics: Animals; Atropine; Cyclic GMP; Enteric Nervous System; Enzyme Inhibitors; Esophagogastric Junction;

2000
Modulation of nitrergic relaxant responses by peptides in the mouse gastric fundus.
    Regulatory peptides, 2001, Apr-02, Volume: 98, Issue:1-2

    Topics: Animals; Apamin; Carbachol; Cholinergic Agonists; Chymotrypsin; Electric Stimulation; Enzyme Inhibit

2001
Effect of NO donors on protein phosphorylation in intact vascular and nonvascular smooth muscles.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:4

    Topics: Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase

2001
The influence of nitric oxide donors on the responses to nitrergic nerve stimulation in the mouse duodenum.
    European journal of pharmacology, 2001, Jun-08, Volume: 421, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Duodenum; Electric Stimulation; Enzyme Inhibitors; Ethylm

2001
Neural regulation of in vitro giant contractions in the rat colon.
    American journal of physiology. Gastrointestinal and liver physiology, 2001, Volume: 281, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2001
Dual mechanism of action of nicorandil on rabbit corpus cavernosal smooth muscle tone.
    International journal of impotence research, 2001, Volume: 13, Issue:4

    Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Animals; Enzyme Activation; Enzyme Inhibitors; Gl

2001
Actions of NO donors and endogenous nitrergic transmitter on the longitudinal muscle of rat ileum in vitro: mechanisms involved.
    Life sciences, 2001, Jul-27, Volume: 69, Issue:10

    Topics: Animals; Apamin; Atropine; Calcium Channels; Charybdotoxin; Dose-Response Relationship, Drug; Drug I

2001
Characterization of vagal input to the rat esophageal muscle.
    Autonomic neuroscience : basic & clinical, 2001, Aug-13, Volume: 91, Issue:1-2

    Topics: Animals; Atropine; Enteric Nervous System; Enzyme Inhibitors; Esophagus; Galanin; Gastrointestinal A

2001
The vasorelaxation of cerebral arteries by carbon monoxide.
    Experimental biology and medicine (Maywood, N.J.), 2001, Volume: 226, Issue:9

    Topics: Animals; Carbon Monoxide; Cerebral Arteries; Dinoprost; Dogs; Enzyme Inhibitors; Guanylate Cyclase;

2001
Mechanism of a nitric oxide donor NOR 1-induced relaxation in longitudinal muscle of rat proximal colon.
    Japanese journal of pharmacology, 2001, Volume: 86, Issue:4

    Topics: Animals; Calcium; Carbachol; Colon; Culture Techniques; Cyclic GMP; DNA-Binding Proteins; Dose-Respo

2001
Relaxation and modulation of cyclic AMP production in response to atrial natriuretic peptides in guinea pig tracheal smooth muscle.
    European journal of pharmacology, 2001, Nov-02, Volume: 430, Issue:2-3

    Topics: Adenylyl Cyclases; Animals; Apamin; Atrial Natriuretic Factor; Colforsin; Cyclic AMP; Dose-Response

2001