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1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and Migraine Disorders

1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one has been researched along with Migraine Disorders in 1 studies

1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one: structure given in first source; inhibits guanylyl cyclase
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one : A member of the class of oxadiazoloquinoxalines that is 1H-[1,2,4]oxadiazolo[4,3-a]quinoxaline substituted at position 1 by an oxo group.

Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)

Research Excerpts

ExcerptRelevanceReference
" Results VL-102-evoked acute and chronic mechanical cephalic and hind-paw allodynia in a dose-dependent manner, which was blocked by the migraine medications sumatriptan, propranolol, and topiramate."3.88Soluble guanylyl cyclase is a critical regulator of migraine-associated pain. ( Ben Aissa, M; Bennett, BM; Bertels, Z; Gaisina, IN; Gandhi, R; Lee, SH; Litosh, V; Moye, LS; Novack, M; Pradhan, AA; Thatcher, GR; Tipton, AF; Wang, Y, 2018)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ben Aissa, M1
Tipton, AF1
Bertels, Z1
Gandhi, R1
Moye, LS1
Novack, M1
Bennett, BM1
Wang, Y1
Litosh, V1
Lee, SH1
Gaisina, IN1
Thatcher, GR1
Pradhan, AA1

Other Studies

1 other study available for 1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and Migraine Disorders

ArticleYear
Soluble guanylyl cyclase is a critical regulator of migraine-associated pain.
    Cephalalgia : an international journal of headache, 2018, Volume: 38, Issue:8

    Topics: Adrenergic beta-Antagonists; Allosteric Regulation; Animals; Anticonvulsants; Calcitonin Gene-Relate

2018