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1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and Lung Diseases

1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one has been researched along with Lung Diseases in 1 studies

1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one: structure given in first source; inhibits guanylyl cyclase
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one : A member of the class of oxadiazoloquinoxalines that is 1H-[1,2,4]oxadiazolo[4,3-a]quinoxaline substituted at position 1 by an oxo group.

Lung Diseases: Pathological processes involving any part of the LUNG.

Research Excerpts

ExcerptRelevanceReference
"We designed the present experiments to investigate the involvement of endogenous nitric oxide synthase (NOS) inhibitors, dimethylarginine dimethylaminohydrolase (DDAH) as a hydrolyzing enzyme of the NOS inhibitors, NOS, arginase which shares l-arginine as a common substrate with NOS, and endothelin-1 (ET-1) in the pulmonary dysfunction after induction of experimental subarachnoid hemorrhage (SAH) in the rabbit."7.74Involvement of accumulated NOS inhibitors and endothelin-1, enhanced arginase, and impaired DDAH activities in pulmonary dysfunction following subarachnoid hemorrhage in the rabbit. ( Azuma, H; Imamura, M; Isotani, E; Mizuno, Y; Nagai, A; Ohno, K, 2008)
"We designed the present experiments to investigate the involvement of endogenous nitric oxide synthase (NOS) inhibitors, dimethylarginine dimethylaminohydrolase (DDAH) as a hydrolyzing enzyme of the NOS inhibitors, NOS, arginase which shares l-arginine as a common substrate with NOS, and endothelin-1 (ET-1) in the pulmonary dysfunction after induction of experimental subarachnoid hemorrhage (SAH) in the rabbit."3.74Involvement of accumulated NOS inhibitors and endothelin-1, enhanced arginase, and impaired DDAH activities in pulmonary dysfunction following subarachnoid hemorrhage in the rabbit. ( Azuma, H; Imamura, M; Isotani, E; Mizuno, Y; Nagai, A; Ohno, K, 2008)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mizuno, Y1
Isotani, E1
Ohno, K1
Nagai, A1
Imamura, M1
Azuma, H1

Other Studies

1 other study available for 1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and Lung Diseases

ArticleYear
Involvement of accumulated NOS inhibitors and endothelin-1, enhanced arginase, and impaired DDAH activities in pulmonary dysfunction following subarachnoid hemorrhage in the rabbit.
    Vascular pharmacology, 2008, Volume: 48, Issue:1

    Topics: Acetylcholine; Amidohydrolases; Animals; Arginase; Cyclic GMP; Cyclooxygenase Inhibitors; Dose-Respo

2008