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1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and Intraocular Pressure

1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one has been researched along with Intraocular Pressure in 2 studies

1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one: structure given in first source; inhibits guanylyl cyclase
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one : A member of the class of oxadiazoloquinoxalines that is 1H-[1,2,4]oxadiazolo[4,3-a]quinoxaline substituted at position 1 by an oxo group.

Intraocular Pressure: The pressure of the fluids in the eye.

Research Excerpts

ExcerptRelevanceReference
"We previously reported that several nitric oxide (NO) donors, guanylate cyclase activators, and cyclic GMP lower intraocular pressure (IOP) in rabbits."3.72Incubation of porcine iris-ciliary bodies to study the mechanisms by which nitric oxide donors lower intraocular pressure. ( Kankuri, E; Kotikoski, H; Vapaatalo, H, 2003)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kotikoski, H1
Kankuri, E1
Vapaatalo, H1
Dismuke, WM1
Mbadugha, CC1
Ellis, DZ1

Other Studies

2 other studies available for 1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and Intraocular Pressure

ArticleYear
Incubation of porcine iris-ciliary bodies to study the mechanisms by which nitric oxide donors lower intraocular pressure.
    Medical science monitor : international medical journal of experimental and clinical research, 2003, Volume: 9, Issue:1

    Topics: Animals; Captopril; Ciliary Body; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; G

2003
NO-induced regulation of human trabecular meshwork cell volume and aqueous humor outflow facility involve the BKCa ion channel.
    American journal of physiology. Cell physiology, 2008, Volume: 294, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Animals; Aqueous Humor; Cell Line; Cell Size; Cyclic GMP; Cyclic GMP

2008