1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one has been researched along with Injury, Myocardial Reperfusion in 5 studies
1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one: structure given in first source; inhibits guanylyl cyclase
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one : A member of the class of oxadiazoloquinoxalines that is 1H-[1,2,4]oxadiazolo[4,3-a]quinoxaline substituted at position 1 by an oxo group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The objective of this study was to investigate the effect of L-arginine supplementation on myocardial cell death secondary to hypoxia-reoxygenation." | 7.70 | L-arginine limits myocardial cell death secondary to hypoxia-reoxygenation by a cGMP-dependent mechanism. ( Agulló, L; García-Dorado, D; Inserte, J; Llevadot, J; Paniagua, A; Pyrhonen, P; Soler-Soler, J, 1999) |
| "The objective of this study was to investigate the effect of L-arginine supplementation on myocardial cell death secondary to hypoxia-reoxygenation." | 3.70 | L-arginine limits myocardial cell death secondary to hypoxia-reoxygenation by a cGMP-dependent mechanism. ( Agulló, L; García-Dorado, D; Inserte, J; Llevadot, J; Paniagua, A; Pyrhonen, P; Soler-Soler, J, 1999) |
| " The present study demonstrated that iNOS-derived superoxide generation was reduced, and that the NO bioavailability was increased, by treatment with the NOS-cofactor, tetrahydrobiopterin (BH4), before I/R in the hearts isolated from diabetic rats." | 1.37 | Reversal of inducible nitric oxide synthase uncoupling unmasks tolerance to ischemia/reperfusion injury in the diabetic rat heart. ( Fujita, M; Ito, S; Iwasaka, T; Katano, T; Okazaki, T; Otani, H; Shimazu, T; Yoshioka, K, 2011) |
| "Melatonin has potent cardioprotective properties." | 1.35 | Melatonin receptor-mediated protection against myocardial ischaemia/reperfusion injury: role of its anti-adrenergic actions. ( Genade, S; Genis, A; Huisamen, B; Lochner, A; Ytrehus, K, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Genade, S | 1 |
| Genis, A | 1 |
| Ytrehus, K | 1 |
| Huisamen, B | 1 |
| Lochner, A | 1 |
| Okazaki, T | 1 |
| Otani, H | 1 |
| Shimazu, T | 1 |
| Yoshioka, K | 1 |
| Fujita, M | 1 |
| Katano, T | 1 |
| Ito, S | 1 |
| Iwasaka, T | 1 |
| Berti, F | 1 |
| Manfredi, B | 1 |
| Mantegazza, P | 1 |
| Rossoni, G | 1 |
| Maas, O | 1 |
| Donat, U | 1 |
| Frenzel, M | 1 |
| Rütz, T | 1 |
| Kroemer, HK | 1 |
| Felix, SB | 1 |
| Krieg, T | 1 |
| Agulló, L | 1 |
| García-Dorado, D | 1 |
| Inserte, J | 1 |
| Paniagua, A | 1 |
| Pyrhonen, P | 1 |
| Llevadot, J | 1 |
| Soler-Soler, J | 1 |
5 other studies available for 1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Melatonin receptor-mediated protection against myocardial ischaemia/reperfusion injury: role of its anti-adrenergic actions.
Topics: Adrenergic Antagonists; Animals; Colforsin; Cyclic AMP; Guanylate Cyclase; Heart; Indoles; Isoproter | 2008 |
Reversal of inducible nitric oxide synthase uncoupling unmasks tolerance to ischemia/reperfusion injury in the diabetic rat heart.
Topics: Animals; Biopterins; Cyclic GMP; Diabetes Complications; Diabetes Mellitus, Experimental; Dithiothre | 2011 |
Procyanidins from Vitis vinifera seeds display cardioprotection in an experimental model of ischemia-reperfusion damage.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Biflavonoids; Cardiotonic Agents; Catechin; Dose-Respo | 2003 |
Vardenafil protects isolated rat hearts at reperfusion dependent on GC and PKG.
Topics: Animals; Calcium; Carbazoles; Cell Adhesion Molecules; Cell Death; Cell Line; Cyclic GMP-Dependent P | 2008 |
L-arginine limits myocardial cell death secondary to hypoxia-reoxygenation by a cGMP-dependent mechanism.
Topics: Animals; Arginine; Cell Death; Cells, Cultured; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Hy | 1999 |