1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one has been researched along with Inflammation in 5 studies
1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one: structure given in first source; inhibits guanylyl cyclase
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one : A member of the class of oxadiazoloquinoxalines that is 1H-[1,2,4]oxadiazolo[4,3-a]quinoxaline substituted at position 1 by an oxo group.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The objective of the present paper was to evaluate the relevance of neuronal balance of cyclic AMP and cyclic GMP concentration for functional regulation of nociceptor sensitivity during inflammation." | 3.70 | Pharmacological modulation of secondary mediator systems--cyclic AMP and cyclic GMP--on inflammatory hyperalgesia. ( Cunha, FQ; Ferreira, SH; Teixeira, MM, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lim, DG | 1 |
| Sweeney, S | 1 |
| Bloodsworth, A | 1 |
| White, CR | 1 |
| Chumley, PH | 1 |
| Krishna, NR | 1 |
| Schopfer, F | 1 |
| O'Donnell, VB | 1 |
| Eiserich, JP | 1 |
| Freeman, BA | 1 |
| Connelly, L | 1 |
| Jacobs, AT | 1 |
| Palacios-Callender, M | 1 |
| Moncada, S | 1 |
| Hobbs, AJ | 1 |
| Van Crombruggen, K | 1 |
| Van Nassauw, L | 1 |
| Demetter, P | 1 |
| Cuvelier, C | 1 |
| Timmermans, JP | 1 |
| Lefebvre, RA | 1 |
| Cunha, FQ | 1 |
| Teixeira, MM | 1 |
| Ferreira, SH | 1 |
| Tao, YX | 1 |
| Johns, RA | 1 |
5 other studies available for 1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and Inflammation
| Article | Year |
|---|---|
Nitrolinoleate, a nitric oxide-derived mediator of cell function: synthesis, characterization, and vasomotor activity.
Topics: Animals; Aorta, Thoracic; Chromatography, High Pressure Liquid; Cyclic GMP; Endothelium, Vascular; E | 2002 |
Macrophage endothelial nitric-oxide synthase autoregulates cellular activation and pro-inflammatory protein expression.
Topics: Animals; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Homeostasis; In Vitro Techniques; Inflamm | 2003 |
Influence of soluble guanylate cyclase inhibition on inflammation and motility disturbances in DSS-induced colitis.
Topics: Animals; Colitis; Cyclic GMP; Dextran Sulfate; Disease Models, Animal; Enzyme Inhibitors; Guanylate | 2008 |
Pharmacological modulation of secondary mediator systems--cyclic AMP and cyclic GMP--on inflammatory hyperalgesia.
Topics: Animals; Bradykinin; Carrageenan; Cyclic AMP; Cyclic GMP; Dinoprostone; Dopamine; Hyperalgesia; Infl | 1999 |
Activation and up-regulation of spinal cord nitric oxide receptor, soluble guanylate cyclase, after formalin injection into the rat hind paw.
Topics: Animals; Behavior, Animal; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; | 2002 |