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1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and Endotoxin Shock

1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one has been researched along with Endotoxin Shock in 6 studies

1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one: structure given in first source; inhibits guanylyl cyclase
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one : A member of the class of oxadiazoloquinoxalines that is 1H-[1,2,4]oxadiazolo[4,3-a]quinoxaline substituted at position 1 by an oxo group.

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's4 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Preiser, JC1
Sun, Q1
Hadj-Sadok, D1
Vincent, JL1
Chen, SJ3
Chen, KH1
Wu, CC3
Yen, MH2
Zingarelli, B1
Haskó, G1
Salzman, AL1
Szabó, C1
Yang, SN1
Lin, CI1
Zacharowski, K1
Berkels, R1
Olbrich, A1
Chatterjee, PK1
Cuzzocrea, S1
Foster, SJ1
Thiemermann, C1

Other Studies

6 other studies available for 1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and Endotoxin Shock

ArticleYear
Differential effects of a selective inhibitor of soluble guanylyl cyclase on global and regional hemodynamics during canine endotoxic shock.
    Shock (Augusta, Ga.), 2003, Volume: 20, Issue:5

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Cardiac Output; Dogs; Enzyme Inhibitors; Guanylate Cyc

2003
Nitric oxide-cyclic GMP contributes to abnormal activation of Na+-K+-ATPase in the aorta from rats with endotoxic shock.
    Shock (Augusta, Ga.), 2005, Volume: 23, Issue:2

    Topics: Animals; Aorta; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Dose-Response Relationship, Drug;

2005
Nitric oxide-independent activation of soluble guanylyl cyclase contributes to endotoxin shock in rats.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: Animals; Aorta; Blood Pressure; Charybdotoxin; Dexamethasone; Endothelium, Vascular; Enzyme Activati

1998
Effects of a novel guanylyl cyclase inhibitor on the vascular actions of nitric oxide and peroxynitrite in immunostimulated smooth muscle cells and in endotoxic shock.
    Critical care medicine, 1999, Volume: 27, Issue:9

    Topics: Animals; Aorta; Cell Respiration; Cells, Cultured; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Te

1999
Abnormal activation of K(+) channels in aortic smooth muscle of rats with endotoxic shock: electrophysiological and functional evidence.
    British journal of pharmacology, 2000, Volume: 131, Issue:2

    Topics: Animals; Aorta; Apamin; Benzimidazoles; Charybdotoxin; Drug Interactions; Enzyme Inhibitors; Glyburi

2000
The selective guanylate cyclase inhibitor ODQ reduces multiple organ injury in rodent models of Gram-positive and Gram-negative shock.
    Critical care medicine, 2001, Volume: 29, Issue:8

    Topics: Animals; Cells, Cultured; Enzyme Inhibitors; Escherichia coli Infections; Guanylate Cyclase; Hemodyn

2001