1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one has been researched along with Endotoxemia in 4 studies
1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one: structure given in first source; inhibits guanylyl cyclase
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one : A member of the class of oxadiazoloquinoxalines that is 1H-[1,2,4]oxadiazolo[4,3-a]quinoxaline substituted at position 1 by an oxo group.
Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Caffeine and ryanodine contractions were augmented during endotoxemia without NOS contribution." | 3.72 | The role of nitric oxide on contractile impairment during endotoxemia in rat diaphragm muscle. ( Ertunc, M; Onur, R; Sara, Y, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Spohr, F | 1 |
| Busch, CJ | 1 |
| Teschendorf, P | 1 |
| Weimann, J | 1 |
| Chen, SJ | 2 |
| Chen, KH | 2 |
| Webb, RC | 1 |
| Yen, MH | 1 |
| Wu, CC | 2 |
| Sara, Y | 1 |
| Ertunc, M | 1 |
| Onur, R | 1 |
4 other studies available for 1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and Endotoxemia
| Article | Year |
|---|---|
Selective inhibition of guanylate cyclase prevents impairment of hypoxic pulmonary vasoconstriction in endotoxemic mice.
Topics: Animals; Dose-Response Relationship, Drug; Endotoxemia; Guanylate Cyclase; Hypoxia; In Vitro Techniq | 2009 |
Abnormal activation of Na+-K+ pump in aortas from rats with endotoxaemia.
Topics: Animals; Aorta, Thoracic; Endotoxemia; Enzyme Inhibitors; Escherichia coli; In Vitro Techniques; Lip | 2003 |
The role of nitric oxide on contractile impairment during endotoxemia in rat diaphragm muscle.
Topics: Animals; Caffeine; Diaphragm; Endotoxemia; Enzyme Inhibitors; Guanidines; In Vitro Techniques; Indaz | 2004 |
Nitric oxide-cyclic GMP contributes to abnormal activation of Na+-K+-ATPase in the aorta from rats with endotoxic shock.
Topics: Animals; Aorta; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Dose-Response Relationship, Drug; | 2005 |