1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one has been researched along with Blood Poisoning in 8 studies
1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one: structure given in first source; inhibits guanylyl cyclase
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one : A member of the class of oxadiazoloquinoxalines that is 1H-[1,2,4]oxadiazolo[4,3-a]quinoxaline substituted at position 1 by an oxo group.
Excerpt | Relevance | Reference |
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"Atorvastatin pretreatment, however, prevented the decrease in α(1D)-adrenoceptor mRNA expression in septic animals." | 5.37 | Atorvastatin prevents vascular hyporeactivity to norepinephrine in sepsis: role of nitric oxide and α₁-adrenoceptor mRNA expression. ( Ahanger, AA; Choudhury, S; Kandasamy, K; Mishra, SK; More, AS; Parida, S; Prawez, S; Singh, TU, 2011) |
" In a phenylephrine-contracted canine carotid artery ring preparation, we found that both canine and human Lzm-S, at concentrations similar to those found in sepsis, produced vasorelaxation." | 3.74 | Lysozyme, a mediator of sepsis that produces vasodilation by hydrogen peroxide signaling in an arterial preparation. ( Bose, R; Cheng, ZQ; Jacobs, H; Kasian, K; Light, RB; Mink, SN; Santos Martinez, LE, 2008) |
"Sepsis was induced by cecal ligation and puncture (CLP)." | 1.56 | Perivascular adipose tissue phenotype and sepsis vascular dysfunction: Differential contribution of NO, ROS and beta 3-adrenergic receptor. ( Assreuy, J; Barp, CG; Benedet, PO, 2020) |
"Atorvastatin pretreatment, however, prevented the decrease in α(1D)-adrenoceptor mRNA expression in septic animals." | 1.37 | Atorvastatin prevents vascular hyporeactivity to norepinephrine in sepsis: role of nitric oxide and α₁-adrenoceptor mRNA expression. ( Ahanger, AA; Choudhury, S; Kandasamy, K; Mishra, SK; More, AS; Parida, S; Prawez, S; Singh, TU, 2011) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 5 (62.50) | 29.6817 |
2010's | 2 (25.00) | 24.3611 |
2020's | 1 (12.50) | 2.80 |
Authors | Studies |
---|---|
Barp, CG | 1 |
Benedet, PO | 1 |
Assreuy, J | 2 |
Fernandes, D | 1 |
Sordi, R | 1 |
Pacheco, LK | 1 |
Nardi, GM | 1 |
Heckert, BT | 1 |
Villela, CG | 1 |
Lobo, AR | 1 |
Barja-Fidalgo, C | 1 |
Oliveira-Pelegrin, GR | 1 |
Aguila, FA | 1 |
Basso, PJ | 1 |
Rocha, MJ | 1 |
Kandasamy, K | 1 |
Prawez, S | 1 |
Choudhury, S | 1 |
More, AS | 1 |
Ahanger, AA | 1 |
Singh, TU | 1 |
Parida, S | 1 |
Mishra, SK | 1 |
Williams, M | 1 |
Kerkar, S | 1 |
Tyburski, JG | 1 |
Steffes, CP | 1 |
Carlin, AM | 1 |
Wilson, RF | 1 |
Wang, C | 1 |
Mansard, A | 1 |
Giummelly, P | 1 |
Atkinson, J | 1 |
Mink, SN | 2 |
Bose, R | 2 |
Roberts, DE | 1 |
Jacobs, H | 2 |
Duke, K | 1 |
Bose, D | 1 |
Cheng, ZQ | 2 |
Light, RB | 2 |
Kasian, K | 1 |
Santos Martinez, LE | 1 |
8 other studies available for 1h-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one and Blood Poisoning
Article | Year |
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Perivascular adipose tissue phenotype and sepsis vascular dysfunction: Differential contribution of NO, ROS and beta 3-adrenergic receptor.
Topics: Acetophenones; Adipose Tissue; Adrenergic beta-3 Receptor Agonists; Animals; Aorta; Cyclic N-Oxides; | 2020 |
Late, but not early, inhibition of soluble guanylate cyclase decreases mortality in a rat sepsis model.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Cecum; Cyclic GMP; Disease Models, Animal; Drug Administra | 2009 |
Role of central NO-cGMP pathway in vasopressin and oxytocin gene expression during sepsis.
Topics: Animals; Arginine Vasopressin; Cyclic GMP; Enzyme Inhibitors; Gene Expression Regulation; Male; Nitr | 2010 |
Atorvastatin prevents vascular hyporeactivity to norepinephrine in sepsis: role of nitric oxide and α₁-adrenoceptor mRNA expression.
Topics: Animals; Atorvastatin; Enzyme Inhibitors; Guanylate Cyclase; Heptanoic Acids; Mice; Nitric Oxide; No | 2011 |
The roles of cyclic adenosine monophosphate- and cyclic guanosine monophosphate-dependent protein kinase pathways in hydrogen peroxide-induced contractility of microvascular lung pericytes.
Topics: Adenine; Adenylyl Cyclase Inhibitors; Analysis of Variance; Animals; Cell Survival; Cells, Cultured; | 2003 |
Decreased aortic smooth muscle contraction in a rat model of multibacterial sepsis.
Topics: Animals; Aorta; Disease Models, Animal; Endothelial Cells; Enzyme Inhibitors; Guanylate Cyclase; In | 2004 |
Lysozyme binding to endocardial endothelium mediates myocardial depression by the nitric oxide guanosine 3',5' monophosphate pathway in sepsis.
Topics: Animals; Cell Membrane; Cyclic GMP; Dogs; Endocardium; Endothelium; In Vitro Techniques; Muramidase; | 2005 |
Lysozyme, a mediator of sepsis that produces vasodilation by hydrogen peroxide signaling in an arterial preparation.
Topics: Aminoquinolines; Animals; Carotid Artery, Internal; Catalase; Cyclic GMP; Cyclic GMP-Dependent Prote | 2008 |