17-ketosteroids and Uterine-Cervical-Neoplasms
17-ketosteroids has been researched along with Uterine-Cervical-Neoplasms* in 20 studies
Other Studies
20 other study(ies) available for 17-ketosteroids and Uterine-Cervical-Neoplasms
Article | Year |
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[The role of steroid homeostasis in the pathogenesis of cancer of the uterine cervix].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Age Factors; Estrogens; Female; Humans; Menopause; Middle Aged; Pregnanediol; Uterine Cervical Neoplasms | 1982 |
Cushing's syndrome with small cell carcinoma of the uterine cervix.
A 28 year old white women was found to have a cervical tumor in the 25th week of pregnancy. Pathologic examination revealed a nonkeratinizing small cell carcinoma. After delivery by cesarean section, pelvic lymph node exploration was carried out, and all 15 nodes were free of tumor. Her condition was staged as II-A, and she was treated with local radiation. Metastatic disease became manifest almost a year later and was histologically similar to her primary disease. A Cushingoid appearance was noticed and plasma cortisol levels were elevated. Twenty-four hour urinary 17-hydroxycorticosteroid (17-OHCS) and 17-ketosteroid (17-KS) levels were elevated and failed to suppress with dexamethasone. Plasma adrenocorticotropin (ACTH) level was elevated. Electron microscopic examination of the tumor tissue revealed neurosecretory granules. Immunoperoxidase stains for ACTH were positive. The patient's course was one of progressive decline and eventual death. A literature review revealed two other cases in which carcinoma of the uterine cervix was considered to be the source of ectopic ACTH. Some small cell carcinomas of the cervix may arise from cells of the APUD series. Small cell carcinoma of the uterine cervix may behave differently from the more commonly encountered keratinizing and large cell nonkeratinizing carcinomas of the cervix and may not respond as well to standard therapy. Ectopic hormone production, production of abnormal peptides or of vasoactive amines may be more common in small cell carcinoma of the cervix than is currently recognized, and these products may be clinically useful as tumor markers. Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; ACTH Syndrome, Ectopic; Adult; APUD Cells; Carcinoma; Cushing Syndrome; Female; Humans; Hydrocortisone; Paraneoplastic Endocrine Syndromes; Pregnancy; Pregnancy Complications; Uterine Cervical Neoplasms | 1980 |
[Increase in the sensitivity threshold of the hypothalamo-hypophyseal complex to the inhibiting action of dexamethasone in the process of aging and in cervical cancer].
The basal level of the androgenic and glucocorticoid hormones excretion and the level of blood glucocorticoids were studied in 237 females (52--control group, 185--cervical cancer patients) depending on the age and the ovarian function state. Also, the threshold of sensitivity of the hypothalamo-hypophyseal function complex was estimated by a dexametazone test. Healthy females were shown with progressive ageing to have a relative preponderance of glucocorticoid hormones over androgenous ones, which is also observed in cervical cancer irrespective of age group. With ageing in healthy females the threshold of the hypothalamo-hypophyseal complex sensitivity is raised, whereas in cervical cancer patients an increased threshold of the sensitivity is observed in younger age groups and is more manifest. The increased threshold of the hypothalamo-hypophyseal complex sensitivity seems to be one of the mechanisms responsible for the occurrence of such unfavourable hormonal shift (a relative predominance of glucocorticoid hormones over androgenic ones), which in its turn play a significant part in tumors origination and development. Topics: 11-Hydroxycorticosteroids; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aging; Depression, Chemical; Dexamethasone; Female; Humans; Hypothalamo-Hypophyseal System; Menopause; Menstruation; Middle Aged; Uterine Cervical Neoplasms | 1979 |
[Structure and function of steroid active cells in the postmenopausal ovary (electron microscopic and histochemical studies)].
Topics: 17-Ketosteroids; Aged; Estradiol; Estrogens; Female; Histocytochemistry; Humans; Hysterectomy; Menopause; Middle Aged; Ovary; Steroids; Uterine Cervical Neoplasms; Uterine Neoplasms | 1975 |
Endocrine activity in postmenopausal ovaries.
Topics: 17-Ketosteroids; Aged; Carcinoma; Castration; Estrogens; Female; Fumarate Hydratase; Glucosephosphate Dehydrogenase; Glyceraldehyde-3-Phosphate Dehydrogenases; Hexokinase; Humans; Isocitrate Dehydrogenase; L-Lactate Dehydrogenase; Malate Dehydrogenase; Menopause; Microscopy, Electron; Middle Aged; Ovary; Phosphoglycerate Kinase; Phosphopyruvate Hydratase; Uterine Cervical Neoplasms; Uterine Neoplasms | 1974 |
[Investigations of the structural and functional conditions of the postmenopause ovaries in patients with carcinomas of the corpus and neck (author's transl)].
Topics: 17-Ketosteroids; Aged; Cell Division; Endometrium; Enzyme Induction; Estrogens; Female; Histocytochemistry; Humans; Menopause; Microscopy, Electron; Middle Aged; Mitosis; Ovary; Uterine Cervical Neoplasms; Uterine Neoplasms | 1973 |
Short-term administration of cytembena and cyclophosphamide to patients with gynaecological carcinoma. (Evaluation ff laboratory examinations).
Topics: 17-Ketosteroids; Adult; Aged; Alanine Transaminase; Albuminuria; Aspartate Aminotransferases; Blood Cell Count; Blood Sedimentation; Calcium; Carcinoma; Cyclophosphamide; Diarrhea; Endometriosis; Feeding and Eating Disorders; Female; Genital Neoplasms, Female; Hematocrit; Hematopoiesis; Hemoglobins; Humans; L-Lactate Dehydrogenase; Liver Function Tests; Middle Aged; Mucoproteins; Ovarian Neoplasms; Time Factors; Uterine Cervical Neoplasms; Vulvar Neoplasms | 1971 |
[The concentration of 17-neutral ketosteroids and dehydroepiandrosterone in the urine of patients with precancerous diseases and cancer of the uterine cervix].
Topics: 17-Ketosteroids; Adult; Dehydroepiandrosterone; Female; Humans; Middle Aged; Precancerous Conditions; Uterine Cervical Neoplasms | 1969 |
[Status of the adrenal cortex and thyroid gland in patients with cervix neoplasms].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adult; Female; Humans; Middle Aged; Thyroid Gland; Uterine Cervical Neoplasms | 1969 |
[Functional state of the adrenal glands following removal of the ovaries and breast in patients with uterine neoplasms].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adult; Castration; Catecholamines; Female; Humans; Mastectomy; Middle Aged; Uterine Cervical Neoplasms; Uterine Neoplasms | 1969 |
[Comparative study of total 17-ketosteroids and free 17-hydroxycorticosteroids in the plasma of women with carcinoma of the cervix, the uterus, or the ovary].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Age Factors; Aged; Androgens; Carcinoma, Squamous Cell; Castration; Female; Glucocorticoids; Humans; Menopause; Methods; Middle Aged; Ovarian Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms | 1968 |
[Free and total plasma 17-ketosteroids in genital cancers. Study of women with breast or genital cancer and men with prostatic or testicular cancer].
Topics: 17-Ketosteroids; Breast Neoplasms; Castration; Female; Genital Neoplasms, Female; Humans; Male; Ovarian Neoplasms; Prostatic Neoplasms; Testicular Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Vaginal Neoplasms | 1968 |
[On a functional examination of the adrenal cortex for the purpose of radiotherapy].
Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Bone Neoplasms; Chromatography; Dehydroepiandrosterone; Female; Hodgkin Disease; Humans; Injections, Intramuscular; Laryngeal Neoplasms; Male; Nasopharyngeal Neoplasms; Neoplasms; Pituitary-Adrenal System; Polarography; Prostatic Neoplasms; Tibia; Uterine Cervical Neoplasms | 1967 |
[The effects of high energy X-ray irradiation on the ovaries of women of reproductive age].
Topics: 17-Ketosteroids; Adult; Body Temperature; Estrogens; Female; Fertility; Humans; Hysterosalpingography; Middle Aged; Ovary; Radiation Effects; Radiotherapy, High-Energy; Uterine Cervical Neoplasms | 1967 |
[Hormone determinations during 17-hydroxyprogesterone-capronate therapy].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aminocaproates; Chromatography; Colorimetry; Creatinine; Estrogens; Female; Follicle Stimulating Hormone; Gonadotropins; Humans; Hydroxyprogesterones; Leiomyoma; Pregnanediol; Uterine Cervical Neoplasms; Uterine Neoplasms | 1967 |
[Comparative study of total 17-ketosteroids and free plasmatic 17-hydroxycorticosteroids in women with cancer of the uterine cervix, of the uterine body or of the ovary].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aged; Castration; Female; Humans; Menopause; Middle Aged; Ovarian Neoplasms; Plasma; Uterine Cervical Neoplasms; Uterine Neoplasms | 1966 |
Hormonal excretions in patients with carcinoma of the cervix.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Animals; Black or African American; Calcium; Creatine; Female; Gonadotropins; Humans; Luteinizing Hormone; Mice; Urine; Uterine Cervical Neoplasms | 1966 |
EXCRETION OF OESTROGENS, 17-KETOSTEROIDS AND 17-OH-CORTICOSTEROIDS IN IRRADIATED CERVICAL CARCINOMA.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Carcinoma; Carcinoma, Squamous Cell; Estradiol; Estriol; Estrogens; Estrone; Female; Humans; Neoplasms; Radium; Urine; Uterine Cervical Neoplasms | 1963 |
[CHANGES IN THE 17-KETOSTEROID AND 17-OHCS (ALPHA-KETOL) EXCRETION DURING RADIOTHERAPY IN WOMEN WITH GENITAL CANCER].
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Biological Transport; Body Fluids; Female; Humans; Neoplasms; Radium; Urine; Uterine Cervical Neoplasms | 1963 |
[Changes in the elimination of 17-ketosteroids and 17-hydroxycorticosteroids during radiotherapy of female genital carcinoma].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenalectomy; Animals; Female; Humans; Radiotherapy; Uterine Cervical Neoplasms | 1963 |