17-ketosteroids has been researched along with Neoplasms* in 105 studies
4 review(s) available for 17-ketosteroids and Neoplasms
| Article | Year |
|---|---|
17beta-Hydroxysteroid dehydrogenase inhibitors: a patent review.
17beta-Hydroxysteroid dehydrogenases (17beta-HSDs) mainly catalyze the reduction of C17-ketosteroids to their corresponding hydroxylated forms as well as the reverse reaction (oxidation). Able to convert inactive or less active steroid hormones into more potent ones and vice versa, certain 17beta-HSDs play a key role, especially in the regulation of estrogen and androgen levels. The therapeutic potential of this enzyme family, especially for the treatment of breast cancer, prostate cancer, acne and osteoporosis, then stimulated the development of inhibitors of 17beta-HSDs and important progress was achieved over the last years.. This review article reports all patent applications related to the inhibitors of 17beta-HSDs, including some articles needed to complement the information presented.. Readers will be informed about the role and function of 17beta-HSDs in the first section and about the history of inhibitor development in the second section. Furthermore, in the third and main section, the readers will learn about the structures of patented inhibitors originating from different companies and academic groups.. The increase in the number of 17beta-HSD inhibitors reported in the last years augurs well for the future. The challenge is now to translate these results into clinical studies to allow determination of the therapeutic usefulness of 17beta-HSD inhibitors. Topics: 17-Hydroxysteroid Dehydrogenases; 17-Ketosteroids; Acne Vulgaris; Animals; Clinical Trials as Topic; Drug Design; Enzyme Inhibitors; Humans; Neoplasms; Osteoporosis; Patents as Topic | 2010 |
Biochemical procedures in different forms of cancer.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acid Phosphatase; Adrenal Gland Neoplasms; Alkaline Phosphatase; Amino Acids; Amylases; Bone Neoplasms; Breast Neoplasms; Carcinoid Tumor; Catecholamines; Chorionic Gonadotropin; Clinical Enzyme Tests; Clinical Laboratory Techniques; Female; Glucose-6-Phosphate Isomerase; Humans; Hydroxyindoleacetic Acid; L-Lactate Dehydrogenase; Liver Neoplasms; Male; Neoplasms; Neoplasms, Nerve Tissue; Neuroblastoma; Nucleotidases; Pancreatic Neoplasms; Pheochromocytoma; Pregnancy; Prostatic Neoplasms; Trophoblastic Neoplasms; Vanilmandelic Acid | 1971 |
Chemical measurements in the detection of cancer. A review.
Topics: 17-Ketosteroids; Animals; Blood Chemical Analysis; Guinea Pigs; Humans; Hyaluronoglucosaminidase; Immunoassay; Isoenzymes; L-Lactate Dehydrogenase; Metals; Neoplasms; Phosphorus Isotopes | 1970 |
SELECTIVE CRITERIA FOR SURGICAL REMOVAL OF THE ENDOCRINE GLANDS IN ADVANCED BREAST CANCER.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenalectomy; Androgens; Breast Neoplasms; Calcium; Castration; Drug Therapy; Endocrine Glands; Estrogens; Glucuronidase; Humans; Hypophysectomy; Mastectomy; Metabolism; Neoplasm Metastasis; Neoplasms; Urine | 1965 |
101 other study(ies) available for 17-ketosteroids and Neoplasms
| Article | Year |
|---|---|
Computational determination of binding structures and free energies of glucose 6-phosphate dehydrogenase with novel steroid inhibitors.
Glucose 6-phosphate dehydrogenase (G6PD), the first and the rate-limiting enzyme in the pentose phosphate pathway (PPP), catalyzes the oxidation of G6P to 6-phosphogluconolactone and the reduction of NADP(+) to NADPH. Its key role in cancer promotes the development of a potent and selective inhibitor that might increase cancer cell death when combined with radiotherapy. In the present study, we investigated the detailed binding modes and binding free energies for G6PD interacting with a promising series of recently developed inhibitors, i.e., the steroid derivatives, by performing molecular docking, molecular dynamics (MD) simulations, and binding free energy calculations. The docking indicates that the inhibitors occupy the binding sites of both G6P and NADP(+). The calculated binding free energies on the basis of the MD-simulated enzyme-inhibitor complexes are in good agreement with the experimental activity data for all of the examined inhibitors. The valuable insights into the detailed enzyme-inhibitor binding including the important intermolecular interactions, e.g., the hydrogen bond interaction and the hydrophobic interaction, have been provided. The computational results provide new insights into future rational design of more potent inhibitors of G6PD as a treatment for cancer. Topics: 17-Ketosteroids; Antineoplastic Agents; Catalytic Domain; Drug Design; Enzyme Inhibitors; Glucosephosphate Dehydrogenase; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Targeted Therapy; Neoplasms; Protein Binding; Thermodynamics | 2014 |
[Change in the excretion of adrenal steroids as dependent on the chlodithane (2,4'-DDD) concentration in the blood of oncological patients].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenocarcinoma; Adrenal Cortex Hormones; Adrenal Glands; Breast Neoplasms; Circadian Rhythm; Female; Humans; Kidney Neoplasms; Male; Mitotane; Neoplasms; Prostatic Neoplasms | 1976 |
Biochemical tests in the diagnosis of cancer.
Topics: 17-Ketosteroids; Acid Phosphatase; Alkaline Phosphatase; alpha-Fetoproteins; Bence Jones Protein; Female; Fructose-Bisphosphate Aldolase; Glucose-6-Phosphate Isomerase; Gonadotropins; Hexosamines; Humans; Hydroxyindoleacetic Acid; L-Lactate Dehydrogenase; Male; Neoplasms; Pregnancy; Vanilmandelic Acid | 1975 |
[Proceedings: Blood 11-deoxy-17-KS, dehydroepiandrosterone (DHEA) in dehydroepiandrosterone sulfate (DHEAS) in the field of internal medicine].
Topics: 17-Ketosteroids; Adult; Dehydroepiandrosterone; Female; Humans; Hypertension; Male; Middle Aged; Neoplasms | 1974 |
17-Ketosteroid excretion, myasthenia, and cancer.
Topics: 17-Ketosteroids; Humans; Myasthenia Gravis; Neoplasms; Sarcoidosis | 1972 |
Adrenal and testicular contribution to plasma oestrogens.
Topics: 17-Ketosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Androstanes; Breast Neoplasms; Castration; Dehydroepiandrosterone; Dexamethasone; Estradiol; Estrone; Female; Humans; Hydrocortisone; Hypertension; Iliac Vein; Male; Menopause; Middle Aged; Neoplasms; Radioligand Assay; Renal Veins; Testis; Testosterone | 1972 |
[Determination of glucocorticoids in the urine of stationary tumor patients].
Topics: 17-Ketosteroids; Corticosterone; Fluorometry; Glucocorticoids; Humans; Hydrocortisone; Neoplasms; Stress, Psychological | 1970 |
[Paraneoplastic hypercorticism syndrome].
Topics: 17-Ketosteroids; Adrenocortical Hyperfunction; Aged; Bone Neoplasms; Esophageal Neoplasms; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Skin Neoplasms; Stomach Neoplasms | 1969 |
Studies on the fractionation of urinary 11-deoxy-17-ketosteroids with gas-liquid chromatography, with special reference to the evaluation of determination procedures and results in aged subjects and in several pathological conditions.
Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Chromatography, Gas; Female; Humans; Hyperthyroidism; Liver Cirrhosis; Male; Methods; Middle Aged; Neoplasms; Sex Factors; Triiodothyronine | 1968 |
[Study of free plasma 17-ketosteroids in patients having cancers other than genital and breast cancers].
Topics: 17-Ketosteroids; Bronchial Neoplasms; Female; Gastrointestinal Neoplasms; Hodgkin Disease; Humans; Kidney Neoplasms; Male; Neoplasms | 1968 |
[On a functional examination of the adrenal cortex for the purpose of radiotherapy].
Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Bone Neoplasms; Chromatography; Dehydroepiandrosterone; Female; Hodgkin Disease; Humans; Injections, Intramuscular; Laryngeal Neoplasms; Male; Nasopharyngeal Neoplasms; Neoplasms; Pituitary-Adrenal System; Polarography; Prostatic Neoplasms; Tibia; Uterine Cervical Neoplasms | 1967 |
CARCINOMA OF MALE BREAST IN ASSOCIATION WITH THE KLINEFELTER SYNDROME.
Topics: 17-Ketosteroids; Adenocarcinoma; Adenocarcinoma, Scirrhous; Adrenal Cortex Hormones; Biopsy; Breast; Breast Neoplasms; Carcinoma, Ductal; Chromosomes; Fluids and Secretions; Gonadotropins; Gynecomastia; Humans; Klinefelter Syndrome; Male; Neoplasm Metastasis; Neoplasms; Pathology; Urine | 1965 |
[VIRILIZING SYNDROME CAUSED BY AN OVARIAN TUMOR].
Topics: 17-Ketosteroids; Female; Humans; Leydig Cell Tumor; Male; Neoplasms; Ovarian Neoplasms; Pathology; Retropneumoperitoneum; Surgical Procedures, Operative; Syndrome; Virilism | 1965 |
A CASE OF LARGE PRIMARY CARCINOMA OF THE ADRENAL.
Topics: 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenalectomy; Carcinoma; Diagnosis, Differential; Neoplasms; Pathology; Radiography; Urine | 1965 |
FEMINIZING ADRENOCORTICAL TUMORS IN THE MALE. A REVIEW OF 52 CASES INCLUDING A CASE REPORT.
Topics: 17-Ketosteroids; Adrenal Gland Neoplasms; Diagnosis, Differential; Estrogens; Humans; Metabolism; Neoplasms; Pathology; Statistics as Topic; Urine | 1965 |
ESTRADURIN (POLYOESTRADIOL PHOSPHATE) IN THE TREATMENT OF PROSTATIC CARCINOMA. A CLINICAL AND STEROID METABOLIC STUDY.
Topics: 17-Ketosteroids; Castration; Estradiol; Humans; Male; Neoplasms; Orchiectomy; Prostatic Neoplasms; Testis | 1965 |
HYPERADRENOCORTICISM ASSOCIATED WITH "REACTIVATED" PROSTATIC CARCINOMA.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenocarcinoma; Adrenalectomy; Adrenocortical Hyperfunction; Aged; Dexamethasone; Diethylstilbestrol; Humans; Male; Neoplasm Metastasis; Neoplasms; Pathology; Prostatic Neoplasms; Surgical Procedures, Operative; Toxicology; Urine | 1965 |
ISLET-CELL CARCINOMA (ZOLLINGER-ELLISON SYNDROME) WITH FULMINATING ADRENOCORTICAL HYPERFUNCTION AND HYPOKALEMIA.
The production of ACTH-like material by tumours arising in non-endocrine tissue may initiate severe adrenocortical hyperfunction. The pathogenesis and clinical and laboratory features of Cushing's syndrome associated with such tumours are characteristic. The autonomous production by the tumour of ACTH-like material cannot be suppressed by exogenous corticoids. The onset of clinical symptoms is rapid; muscle wasting, general weakness, thirst and peripheral edema predominate, and the classical signs of Cushing's syndrome may be absent. High levels of plasma 17-hydroxycorticosteroids and urinary 17-hydroxycorticosteroids and 17-ketosteroids, usually with normal levels of urinary aldosterone, commonly occur. Hypokalemic alkalosis unresponsive to replacement therapy may cause death. In the case reported herein, the intriguing possibility exists that two hormone-like substances were produced by the primary growth and its metastases: one, ACTH-like, to account for the adrenal hyperplasia and Cushing's syndrome; and another, gastrin-like, giving rise to the ulcerogenic diathesis. Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma, Islet Cell; Adrenalectomy; Adrenocortical Hyperfunction; Autopsy; Carcinoma, Islet Cell; Chloramphenicol; Cushing Syndrome; Drug Therapy; Gastrins; Humans; Hypokalemia; Neoplasm Metastasis; Neoplasms; Pancreatic Neoplasms; Pathology; Spironolactone; Zollinger-Ellison Syndrome | 1965 |
ARRHENOBLASTOMA OF THE OVARY.
Topics: 17-Ketosteroids; Adolescent; Child; Female; Geriatrics; Humans; Male; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasms; Ovarian Neoplasms; Pathology; Pregnancy; Prognosis; Sertoli-Leydig Cell Tumor; Surgical Procedures, Operative; Virilism | 1965 |
[Thoughts on problems of laboratory control of malignant diseases].
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Blood Protein Disorders; Blood Protein Electrophoresis; Clinical Laboratory Techniques; Electrolytes; Humans; In Vitro Techniques; Kidney Function Tests; Neoplasms | 1965 |
PITUITARY TUMORS IN CUSHING'S SYNDROME.
Topics: 17-Ketosteroids; Adenoma; Adenoma, Acidophil; Adenoma, Basophil; Adolescent; Adrenal Cortex Hormones; Adrenalectomy; Adrenocorticotropic Hormone; Aldosterone; Blood Chemical Analysis; Choristoma; Cushing Syndrome; Follicle Stimulating Hormone; Humans; Hydrocortisone; Hypophysectomy; Iodine Isotopes; Myxedema; Neoplasms; Pathology; Pituitary Neoplasms; Radiography; Radioisotopes; Radionuclide Imaging; Thyroid Function Tests; Urine | 1964 |
EFFECT OF STEROIDS ON HUMAN CELL CULTURES; SUSTAINING EFFECT OF HYDROCORTISONE.
Topics: 17-Ketosteroids; Androsterone; Dehydroepiandrosterone; Estradiol; Etiocholanolone; Hydrocortisone; Hydroxyprogesterones; Medroxyprogesterone; Neoplasms; Pharmacology; Progestins; Research; Steroids; Testosterone; Tissue Culture Techniques | 1964 |
URINARY 11-DEOXY-17-OXOSTEROIDS IN BRITISH AND JAPANESE WOMEN WITH REFERENCE TO THE INCIDENCE OF BREAST CANCER.
Topics: 17-Ketosteroids; Asian People; Breast Neoplasms; Ethnicity; Female; Humans; Incidence; Japan; Neoplasms; Thyroid Gland; United Kingdom; Urine; White People | 1964 |
[INFLUENCE OF TESTOSTERONE ADMINISTRATION ON PLASMA 17-KETOSTEROID LEVELS].
Topics: 17-Ketosteroids; Androsterone; Etiocholanolone; Neoplasms; Pharmacology; Plasma; Testosterone | 1964 |
CLINICAL AND STATISTICAL STUDIES OF TUMORS OF RETICULOENDOTHELIAL SYSTEM IN JAPAN.
Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Blood Sedimentation; Child; Geriatrics; Hodgkin Disease; Humans; Japan; Leukemia; Leukemia, Lymphoid; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mesothelioma; Mononuclear Phagocyte System; Neoplasms; Osteosarcoma; Sarcoma; Sarcoma, Ewing; Urine | 1964 |
[EXPERIMENTAL STUDIES ON CANCER AND CONSTITUTION (7). CANCER AND PITUITARY-ADRENAL FUNCTION].
Topics: 17-Ketosteroids; Gonadotropins; Gonadotropins, Pituitary; Guinea Pigs; Hypophysectomy; Neoplasms; Physiology; Pituitary Gland; Rabbits; Rats; Research; Sarcoma; Sarcoma, Yoshida; Urine | 1964 |
HORMONE EXCRETION PATTERNS IN BREAST AND PROSTATE CANCER ARE ABNORMAL.
In patients with breast and prostate cancer hormone excretion patterns differ in a similar way from patterns in persons without cancer. Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Aged; Androsterone; Breast Neoplasms; Creatine; Creatinine; Estradiol; Estriol; Estrone; Etiocholanolone; Gonadotropins; Humans; Male; Menopause; Metabolism; Neoplasms; Pregnanediol; Prostatic Neoplasms; Urine | 1964 |
PROSTATIC CANCER OF A YOUNG PERSON WITH PRIMARY HYPOGONADISM.
Topics: 17-Ketosteroids; Castration; Cesium Isotopes; Cobalt Isotopes; Drug Therapy; Estrogens; Gonadotropins; Humans; Hypogonadism; Male; Neoplasms; Pathology; Phosphorus Isotopes; Prostatectomy; Prostatic Neoplasms; Radioisotope Teletherapy; Testis; Urine; Urography | 1964 |
[STUDY OF FREE AND CONJUGATED BLOOD 17-KETOSTEROIDS IN WOMEN WITH BREAST OR GENITAL EPITHELIOMA].
Topics: 17-Ketosteroids; Adolescent; Blood Chemical Analysis; Breast; Breast Neoplasms; Carcinoma; Female; Humans; Neoplasms; Ovarian Neoplasms; Uterine Neoplasms | 1964 |
[TUMORS OF THE URINARY TRACT AND THE HORMONAL ENVIRONMENTS. IV. THYMUS AND TUMORS OF THE URINARY TRACT].
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Blood Chemical Analysis; Eosinophils; Gonadotropins; Humans; Leukocyte Count; Male; Neoplasms; Neoplasms, Experimental; Physiology; Prostatic Neoplasms; Rabbits; Rats; Research; Surgical Procedures, Operative; Thymectomy; Thymus Gland; Urinary Tract; Urine | 1964 |
BILATERAL OVARIAN FIBROMAS OCCURRING BEFORE THE MENARCHE.
Topics: 17-Ketosteroids; Child; Female; Fibroma; Humans; Menarche; Neoplasms; Ovarian Neoplasms; Pathology; Puberty; Sexual Maturation; Surgical Procedures, Operative; Thecoma | 1964 |
MULTIPLE BRONCHIAL ADENOMAS, CUSHING'S SYNDROME AND HYPOKALEMIC ALKALOSIS. REPORT OF A CASE.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenalectomy; Adrenocorticotropic Hormone; Alkalosis; Bartter Syndrome; Bronchial Neoplasms; Cushing Syndrome; Dexamethasone; Heart Arrest; Humans; Hypokalemia; Metyrapone; Neoplasms; Neoplasms, Multiple Primary; Pathology; Radiography, Thoracic; Urine | 1964 |
THE FEMINIZING SYNDROME IN MALE SUBJECTS WITH ADRENOCORTICAL NEOPLASMS.
Topics: 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenogenital Syndrome; Estradiol; Estriol; Estrogens; Estrone; Follicle Stimulating Hormone; Gynecomastia; Humans; Hypogonadism; Male; Neoplasm Metastasis; Neoplasms; Pregnanediol; Surgical Procedures, Operative; Testis; Urine | 1964 |
ADRENOCORTICAL CARCINOMA WITH FEMINIZATION AND HYPERTENSION ASSOCIATED WITH A DEFECT IN 11-BETA-HYDROXYLATION.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acne Vulgaris; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocortical Carcinoma; Adrenocorticotropic Hormone; Androgens; Androsterone; Antineoplastic Agents; Diuretics; Edema; Estrogens; Etiocholanolone; Feminization; Humans; Hydroxylation; Hypertension; Male; Metyrapone; Neoplasms; Pharmacology | 1964 |
THE DEVELOPMENT OF GIRLS DEPRIVED OF OVARIAN FUNCTION BEFORE THE MENARCHE.
Topics: 17-Ketosteroids; Adolescent; Breast; Carcinoma; Castration; Child; Chorionic Gonadotropin; Dysgerminoma; Estradiol; Estriol; Estrogens; Estrone; Female; Gonadotropins; Gonadotropins, Pituitary; Growth; Humans; Hysterectomy; Menarche; Menstruation; Neoplasms; Ovarian Neoplasms; Ovary; Pituitary Gland; Pituitary-Adrenal Function Tests; Puberty; Sexual Maturation; Urine | 1964 |
URINARY STEROID ESTIMATIONS IN THE PREDICTION OF RESPONSE TO ADRENALECTOMY OR HYPOPHYSECTOMY.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenalectomy; Breast Neoplasms; Castration; Female; Fluids and Secretions; Humans; Hypophysectomy; Metabolism; Neoplasms; Ovary; Prognosis; Urine | 1964 |
THE EFFECT OF HUMAN GONADOTROPHINS ON THE OVARIES OF RADIOLOGICALLY CASTRATED WOMEN.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Castration; Chorionic Gonadotropin; Estradiol; Estriol; Estrone; Female; Follicle Stimulating Hormone; Gonadotropins; Humans; Neoplasms; Ovary; Pharmacology; Physiology; Pregnanediol | 1964 |
ADRENO-CORTICAL HYPERACTIVITY--TWO INTERESTING CASES.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Abdomen; Abdomen, Acute; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Adrenogenital Syndrome; Betamethasone; Diagnosis; Humans; Neoplasms; Urine | 1964 |
ALDOSTERONE EXCRETION IN PRETECTAL DISEASE.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Aldosterone; Blood Chemical Analysis; Brain Diseases; Brain Neoplasms; Cerebral Hemorrhage; Cerebral Ventricles; Child; Gonadotropins; Humans; Mesencephalon; Neoplasms; Pharmacology; Pineal Gland; Radiography; Sodium Chloride; Tectum Mesencephali; Urine | 1964 |
HORMONAL THERAPY IN CANCER OF THE BREAST. 23. EFFECT OF 7-ALPHA-METHYL-19-NORTESTOSTERONE ACETATE AND TESTOSTERONE PROPIONATE ON CLINICAL COURSE AND HORMONAL EXCRETION.
Topics: 17-Ketosteroids; Acetates; Antineoplastic Agents; Bilirubin; Biomedical Research; Blood Glucose; Breast Neoplasms; Female; Fluids and Secretions; Gonadotropins; Gonadotropins, Pituitary; Humans; Kidney Function Tests; Nandrolone; Neoplasms; Nitrogen; Prolactin; Testosterone; Testosterone Propionate; Toxicology; Transaminases; Urea; Urine; Virilism | 1964 |
DIFFERENCES OF STEROID METABOLISM IN BREAST CANCER AFTER HORMONE STIMULATION.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Androgens; Androsterone; Breast Diseases; Breast Neoplasms; Chemistry Techniques, Analytical; Colorimetry; Dehydroepiandrosterone; Estradiol; Estrone; Etiocholanolone; Humans; Hydrocortisone; Lipid Metabolism; Metabolism; Neoplasms; Spectrum Analysis; Testosterone; Triiodothyronine; Urine | 1964 |
[CONTRIBUTION TO THE KNOWLEDGE OF LUNG NEOPLASMS WITH HYPERCORTICISM SYNDROMES].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocortical Hyperfunction; Geriatrics; Humans; Lung Neoplasms; Neoplasms; Pathology; Syndrome; Urine | 1964 |
[ON THE BEHAVIOR OF THE INDIVIDUAL COMPONENTS OF C-17-KETOSTEROIDS IN URINE DURING RADIOTHERAPY OF TUMORS IN RELATION TO TOTAL C-17-KETOSTEROID DETERMINATION].
Topics: 17-Ketosteroids; Body Fluids; Humans; Neoplasms; Urine | 1964 |
[The behavior of the adrenal cortex in the cancer experiment].
Topics: 17-Ketosteroids; Adrenal Cortex; Animals; Breast Neoplasms; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Neoplasms | 1963 |
APPRAISAL OF ADRENOCORTICAL HYPERFUNCTION: PATIENTS WITH CUSHING'S SYNDROME OR "NON-ENDOCRINE" TUMORS.
Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Blood Chemical Analysis; Chromatography; Cortisone; Cushing Syndrome; Dexamethasone; Humans; Hydrocortisone; Neoplasms; Pharmacology; Pituitary-Adrenal Function Tests; Urine | 1963 |
STEROID BIOSYNTHESIS IN VITRO BY A VIRILIZING SUPRARENAL TUMOUR.
Topics: 17-Ketosteroids; Adenoma; Adrenal Cortex Hormones; Androgens; Chromatography; Corticosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; In Vitro Techniques; Mixed Function Oxygenases; Neoplasms; Progesterone; Virilism | 1963 |
HORMONAL THERAPY IN CANCER OF THE BREAST. XXII. EFFECT OF 17ALPHA-METHYL-5BETA-DIHYDROTESTOSTERONE ON CLINICAL COURSE AND HORMONAL EXCRETION.
Topics: 17-Ketosteroids; Androgens; Breast; Breast Neoplasms; Creatine; Creatinine; Desoxycorticosterone; Dihydrotestosterone; Gonadotropins; Humans; Luteinizing Hormone; Lymphatic Metastasis; Neoplasms; Pregnanediol; Prolactin; Urine | 1963 |
[THE SECRETION OF GONADOTROPINS, ESTROGENS AND 17-KETOSTEROIDS IN SOME PRETUMOROUS AND TUMOROUS DISEASES. THE EFFECT OF AGE, MENOPAUSE AND RADIATION CASTRATION].
Topics: 17-Ketosteroids; Aging; Castration; Estrogens; Female; Gonadotropins; Humans; Menopause; Neoplasms; Ovary; Urine | 1963 |
CUSHING'S SYNDROME.
Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Androgens; Androsterone; Carcinoma; Carcinoma, Bronchogenic; Chromatography; Cushing Syndrome; Dehydroepiandrosterone; Etiocholanolone; Geriatrics; Humans; Kidney Function Tests; Neoplasms | 1963 |
EXCRETION OF OESTROGENS, 17-KETOSTEROIDS AND 17-OH-CORTICOSTEROIDS IN IRRADIATED CERVICAL CARCINOMA.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Carcinoma; Carcinoma, Squamous Cell; Estradiol; Estriol; Estrogens; Estrone; Female; Humans; Neoplasms; Radium; Urine; Uterine Cervical Neoplasms | 1963 |
[ON ADRENAL CORTEX TUMORS IN CHILDREN].
Topics: 17-Ketosteroids; Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Child; Cortisone; Desoxycorticosterone; Hydrocortisone; Neoplasms; Surgical Procedures, Operative | 1963 |
MEDICAL TREATMENT OF CANCER OF THE BREAST.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenalectomy; Antineoplastic Agents; Breast Neoplasms; Estradiol; Estriol; Estrone; Humans; Neoplasms; Prednisolone; Pregnanediol; Sterilization; Sterilization, Reproductive; Testosterone | 1963 |
[PERIODICALLY APPEARING DISEASE SYMPTOMS].
Topics: 17-Ketosteroids; Agranulocytosis; Communicable Diseases; Edema; Endocrinology; Etiocholanolone; Familial Mediterranean Fever; Fever; Humans; Joint Diseases; Mononuclear Phagocyte System; Neoplasms; Paralyses, Familial Periodic | 1963 |
[CHANGES IN THE 17-KETOSTEROID AND 17-OHCS (ALPHA-KETOL) EXCRETION DURING RADIOTHERAPY IN WOMEN WITH GENITAL CANCER].
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Biological Transport; Body Fluids; Female; Humans; Neoplasms; Radium; Urine; Uterine Cervical Neoplasms | 1963 |
[EXPERIMENTAL STUDIES ON DIATHESIS AND CANCER. V. EXPERIMENTS ON RESISTANCE TO YOSHIDA SARCOMA PRETREATED WITH HORSE SERUM AND NRES IN DONRYU AND OSAWA RATS].
Topics: 17-Ketosteroids; Adrenal Glands; Animals; Blood; Disease Susceptibility; Erythrocyte Count; Horses; Immune Sera; Leukocyte Count; Neoplasms; Physiology; Pituitary Gland; Rats; Research; Sarcoma, Yoshida; Urine | 1963 |
[EXPERIMENTAL STUDIES ON DIATHESIS AND CANCER. VI. EXPERIMENTS ON RESISTANCE TO YOSHIDA SARCOMA PRETREATED WITH HORSE SERUM AND NRES IN S.D. RATS].
Topics: 17-Ketosteroids; Animals; Blood; Disease Susceptibility; Erythrocyte Count; Horses; Hypophysectomy; Immune Sera; Leukocyte Count; Neoplasms; Rats; Research; Sarcoma; Sarcoma, Yoshida; Urine | 1963 |
[PROLONGED DAILY STUDY OF THE SO-CALLED QUOTIENT OF REDUCING STEROIDS IN A BOY TREATED WITH HUMAN STH AND IN AN ACROMEGALIC PATIENT TREATED WITH COBALT THERAPY].
Topics: 17-Ketosteroids; Acromegaly; Adrenal Cortex Hormones; Androgens; Child; Cobalt; Cobalt Isotopes; Dwarfism; Dwarfism, Pituitary; Growth Hormone; Humans; Hypopituitarism; Male; Neoplasms; Pituitary Diseases; Pituitary Gland; Pituitary Neoplasms; Urine | 1963 |
[EXPLORATION OF THE ACTH HYPOPHYSEAL RESERVE WITH METOPIRONE IN DIFFERENT ENDOCRINOPATHIES].
Topics: 17-Ketosteroids; Acromegaly; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Clinical Laboratory Techniques; Cushing Syndrome; Cysts; Female; Humans; Hypogonadism; Hypopituitarism; Metyrapone; Mineralocorticoid Receptor Antagonists; Neoplasms; Ovary; Pharmacology; Pituitary Gland; Pituitary Neoplasms; Radioisotope Teletherapy; Scleroderma, Systemic; Sexual Infantilism; Toxicology; Urine | 1963 |
[THE FUNCTIONAL STATE OF THE ADRENAL CORTEX IN CERTAIN DISEASES OF THE DIENCEPHALIC REGION AND HYPOPHYSIS].
Topics: 17-Ketosteroids; Adrenal Cortex; Brain Diseases; Brain Neoplasms; Craniopharyngioma; Diencephalon; Eosinophilic Granuloma; Eosinophils; Humans; Hydrocortisone; Neoplasms; Pituitary Gland; Pituitary Irradiation; Pituitary Neoplasms; Pituitary-Adrenal Function Tests | 1963 |
[Columnar chromatographic analysis of C-17-ketosteroids in the urine in the treatment of hormoneindependent tumors with ionizing rays].
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Neoplasms; Radiation; Radiotherapy | 1962 |
[Column-chromatographic analysis of C-17-ketosteroids in the urine in the treatment of non-hormonedependent tumors with ionizing radiation].
Topics: 17-Ketosteroids; Body Fluids; Chromatography; Neoplasms; Radiation, Ionizing | 1962 |
[Urinary excretion of 17-ketosteroid and 17-hydroxy-corticosteroid after the injection of patients with malignant neoplasm using 3-methylcholatherene].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Humans; Injections; Methylcholanthrene; Neoplasms | 1962 |
[SIGNIFICANCE OF URINARY 17-KETOSTEROID FRACTION DETERMINATION IN NORMAL SUBJECTS AND PATIENTS WITH CANCER OF DIGESTIVE TRACT AND PEPTIC ULCER].
Topics: 17-Ketosteroids; Aging; Chromatography; Gastrointestinal Neoplasms; Humans; Neoplasms; Peptic Ulcer; Sex; Urine | 1962 |
[The behavior of glucocorticoids in connection with the radiotherapy of tumors].
Topics: 17-Ketosteroids; Glucocorticoids; Humans; Neoplasms | 1962 |
[Adrenogenital syndrome in an adult woman caused by a benign adrenal tumor with the presence of urinary gonadotropins, very high elimination of 17-ketosteroids and positive response of 17-hydroxycorticoids to ACTH].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adrenogenital Syndrome; Adult; Female; Gonadotropins; Gonadotropins, Pituitary; Humans; Medical Records; Neoplasms | 1960 |
[General effects of ionizing rays in local therapeutic application].
Topics: 17-Ketosteroids; Body Fluids; Humans; Neoplasms; Radiation; Radiotherapy | 1958 |
A case of masculinizing ovarian tumor: use of corticosteroid inhibition test in diagnosis.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Body Fluids; Female; Humans; Neoplasms; Ovarian Neoplasms; Ovary; Prednisone; Virilism | 1958 |
[17-Ketosteroids in the urine. II. Comparative studies on distribution of 17-ketosteroids in the urine of healthy and cancerous women under various hydrolysis conditions].
Topics: 17-Ketosteroids; Body Fluids; Female; Health; Humans; Hydrolysis; Neoplasms | 1958 |
Urinary excretion of 17-ketosteroids in children.
Topics: 17-Ketosteroids; Adrenal Cortex; Adrenal Cortex Diseases; Adrenal Cortex Neoplasms; Child; Humans; Neoplasms; Puberty; Puberty, Precocious; Sexual Maturation | 1958 |
Studies on the adrenal cortex function in malignant haematologic diseases.
Topics: 17-Ketosteroids; Adrenal Cortex; Hematologic Diseases; Hodgkin Disease; Humans; Leukemia; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoma | 1958 |
[Studies on the 17-ketosteroid excretion during roentgen therapy of patients with genital carcinoma; statements on the prognostic value of 17-ketosteroids].
Topics: 17-Ketosteroids; Carcinoma; Female; Genitalia; Genitalia, Female; Humans; Neoplasms; Prognosis; Radiotherapy | 1957 |
[Considerations of 1246 determinations of 17-ketosteroids in 1017 patients with mammary and gynecological pathology; malignant or benign tumors].
Topics: 17-Ketosteroids; Breast; Breast Neoplasms; Female; Genitalia; Genitalia, Female; Humans; Neoplasms; Steroids | 1956 |
[Teratoma of testicle with increased 17-ketosteroid excretion].
Topics: 17-Ketosteroids; Humans; Male; Neoplasms; Steroids; Teratoma; Testis | 1956 |
[Attempted application of determination of urinary 17-ketosteroids in differential diagnosis of cancer of the prostate and chronic prostatitis].
Topics: 17-Ketosteroids; Chronic Disease; Diagnosis, Differential; Humans; Male; Neoplasms; Prostatic Neoplasms; Prostatitis; Steroids | 1956 |
[Clinicopathological conference on a malignant tumor with high urinary 17-ketosteroid excretion].
Topics: 17-Ketosteroids; Adrenal Cortex; Adrenal Cortex Diseases; Bronchi; Hyperplasia; Hypertrophy; Neoplasms; Steroids; Urine | 1955 |
[Chromatography of total 17-ketosteroids in a case of acromegaly due to pituitary adenoma, before, during and after radiotherapy].
Topics: 17-Ketosteroids; Acromegaly; Adenoma; Chromatography; Growth Hormone-Secreting Pituitary Adenoma; Humans; Neoplasms; Pituitary Gland; Pituitary Neoplasms; Radiotherapy; Steroids | 1955 |
The urinary excretion of the 17-ketosteroids in patients affected with neoplasia of the digestive or respiratory apparatus.
Topics: 17-Ketosteroids; Digestive System Neoplasms; Gastrointestinal Tract; Neoplasms; Respiratory System; Respiratory Tract Neoplasms; Steroids; Urine | 1955 |
[Fractionation of 17-ketosteroids and corticoids in urine in gynecological cancer].
Topics: 17-Ketosteroids; Adrenal Cortex; Adrenal Cortex Hormones; Dose Fractionation, Radiation; Female; Humans; Neoplasms; Steroids; Urine; Uterine Neoplasms; Uterus | 1955 |
[Chromatographic fractionation of urinary 17-ketosteroids in neoplasms].
Topics: 17-Ketosteroids; Chemical Fractionation; Chromatography; Dose Fractionation, Radiation; Neoplasms; Steroids; Urine | 1955 |
[Neutral urinary 17-ketosteroids].
Topics: 17-Ketosteroids; Adrenal Cortex; Adrenal Cortex Diseases; Body Fluids; Cushing Syndrome; Humans; Neoplasms; Steroids | 1953 |
Urinary steroid excretion after total adrenalectomy. I. Levels of 17-ketosteroids in cancer patients maintained on varying amounts of cortisone acetate and glycyrrhizin.
Topics: 17-Ketosteroids; Adrenal Glands; Adrenalectomy; Cortisone; Endocrine Glands; Glycyrrhiza; Glycyrrhizic Acid; Neoplasms; Steroids; Urine | 1953 |
Urinary steroids in adrenocortical tumor; excretion of corticoids and 17-ketosteroids on admission, after ACTH, following resection, after withdrawal of ACTH, and upon recurrence of masculinizing carcinoma.
Topics: 17-Ketosteroids; Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Neoplasm Recurrence, Local; Neoplasms; Steroids | 1953 |
[Excretion of 17-ketosteroids in women with genital carcinoma].
Topics: 17-Ketosteroids; Carcinoma; Genitalia; Genitalia, Female; Neoplasms; Steroids | 1953 |
[17-ketosteroid excretion in women during testosterone therapy of genital carcinoma].
Topics: 17-Ketosteroids; Carcinoma; Genitalia; Genitalia, Female; Neoplasms; Steroids; Testosterone | 1953 |
[On 17-ketosteroids in the urine of cancer patients].
Topics: 17-Ketosteroids; Body Fluids; Neoplasms; Steroids; Urine | 1953 |
[On the 17-ketosteroid lowering substance in urine of patients with malignant tumors].
Topics: 17-Ketosteroids; Body Fluids; Neoplasms; Steroids; Urine | 1953 |
[Investigations on the excretion of 17-ketosteroids in healthy and sick women, especially in women with a genital cancer].
Topics: 17-Ketosteroids; Genitalia; Genitalia, Female; Neoplasms; Steroids | 1952 |
[Chemical and crystalline demonstration of C 17 ketosteroids and corticoids in virillising ovarian neoplasms with reference to the differential diagnosis of arrhenoblastoma or hypernephroid].
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Diagnosis, Differential; Female; Humans; Male; Neoplasms; Ovarian Neoplasms; Ovary; Sertoli-Leydig Cell Tumor; Steroids | 1952 |
[Urinary elimination of 17-ketosteroids in genital neoplasms during radium and x-ray therapy].
Topics: 17-Ketosteroids; Genitalia; Genitalia, Female; Neoplasms; Radium; Steroids; X-Ray Therapy | 1952 |
[Studies on 17-ketosteroids in benign and malignant tumors of the uterus].
Topics: 17-Ketosteroids; Female; Humans; Neoplasms; Steroids; Uterine Neoplasms | 1952 |
[Urinary excretion of 17-ketosteroids in patients with malignant neoplastic diseases treated with nitrogen mustards (methyl-bis chlorethylamine)].
Topics: 17-Ketosteroids; Mechlorethamine; Neoplasms; Nitrogen Mustard Compounds; Steroids | 1952 |
[Tissue 17-ketosteroids in rats with chemical sarcomata].
Topics: 17-Ketosteroids; Animals; Neoplasms; Rats; Sarcoma; Steroids | 1951 |
[Urinary secretion of 17-ketosteroids in normal and cancerous persons].
Topics: 17-Ketosteroids; Neoplasms; Steroids; Urinary Tract | 1951 |
[Total urinary excretion of 17-ketosteroids and estrogens in normal and cancerous individuals].
Topics: 17-Ketosteroids; Androgens; Contraceptive Agents, Female; Estradiol Congeners; Estrogens; Female; Humans; Neoplasms | 1951 |
[Excretion of 17 ketosteroids in therapeutic x-irradiation].
Topics: 17-Ketosteroids; Biological Transport; Body Fluids; Neoplasms; Steroids | 1951 |
Excretion diagrams of 17-ketosteroids in patients with tumours of the adrenal cortex.
Topics: 17-Ketosteroids; Adrenal Cortex; Adrenal Cortex Hormones; Hormones; Neoplasms | 1948 |
A Study of the Beta 17 Ketosteroids in a Case of Pseudo-hermaphroditism Due to Adrenal Cortical Tumor.
Topics: 17-Ketosteroids; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenal Glands; Disorders of Sex Development; Humans; Neoplasms | 1948 |
17-Ketosteroids in the diagnosis of adrenal tumors.
Topics: 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenal Glands; Aged; Humans; Neoplasms | 1947 |
Urinary 17-ketosteroids in metabolism; partition of gonadal and adrenocortical hormonal derivatives of normal, endocrine and cancerous patients.
Topics: 17-Ketosteroids; Adrenal Glands; Androgens; Disease; Endocrine Glands; Endocrine System Diseases; Gonadotropins; Gonads; Humans; Neoplasms; Steroids | 1946 |
17-ketosteroids and adrenal tumors.
Topics: 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenal Glands; Androgens; Humans; Neoplasms | 1946 |
Isolation of steroids from the urine of patients with adrenal cortical tumors and adrenal cortical hyperplasia; a new 17-ketosteroid, androstane-3 (alpha) 11-diol-17-one.
Topics: 17-Ketosteroids; Adrenal Glands; Androstanes; Disease; Hyperplasia; Neoplasms; Steroids; Urine | 1945 |