17-ketosteroids and Lymphoma

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Aged; Aldosterone; Cephalothin; Evaluation Studies as Topic; Gentamicins; Humans; Lymphoma; Male; Methods; Nasopharyngeal Neoplasms; Pneumonia, Staphylococcal; Sodium; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors

Mouse lymphoma cells in culture which are killed by adrenal steroids contain specific cortisol receptors that may be involved in the initial events of hormone action. The similarity of these receptors to those in hepatoma tissue culture cells, where adrenal steroids induce tyrosine aminotransferase, suggests that certain aspects of steroid action are similar in the two systems. In three steroid-resistant lymphoma cell populations specific binding was less than in the parent lines, suggesting that conversion to steroid resistance may be associated with changes in specific steroid binding.

Topics: 17-Ketosteroids; Androstanes; Animals; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Culture Techniques; Cytoplasm; Enzyme Induction; Hydrocortisone; Hydroxyprogesterones; Liver Neoplasms; Lymphoma; Mice; Receptors, Drug; Testosterone; Tritium; Tyrosine Transaminase

Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Blood Sedimentation; Child; Geriatrics; Hodgkin Disease; Humans; Japan; Leukemia; Leukemia, Lymphoid; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mesothelioma; Mononuclear Phagocyte System; Neoplasms; Osteosarcoma; Sarcoma; Sarcoma, Ewing; Urine

Topics: 17-Ketosteroids; Adenocarcinoma; Biomedical Research; Blood; Calcium; Chlorides; Creatine; Creatinine; Drug Therapy; Hodgkin Disease; Humans; Iodine Isotopes; Leukemia; Leukemia, Lymphoid; Liver; Lymphocytes; Lymphoma; Lymphoma, Non-Hodgkin; Metabolism; Multiple Myeloma; Nitrogen; Phosphorus; Potassium; Prednisone; Sodium; Uric Acid; Water

Topics: 17-Ketosteroids; Adrenal Cortex; Hematologic Diseases; Hodgkin Disease; Humans; Leukemia; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoma