17-ketosteroids and Klinefelter-Syndrome

Topics: 17-Ketosteroids; Adolescent; Adrenal Hyperplasia, Congenital; Androgen-Insensitivity Syndrome; Child; Child, Preschool; Chorionic Gonadotropin; Diagnosis, Differential; Disorders of Sex Development; Female; Genetic Counseling; Genitalia, Female; Genitalia, Male; Humans; Hypospadias; Infant; Klinefelter Syndrome; Male; Mosaicism; Pregnanetriol; Progesterone; Psychosexual Development; Sex Chromosome Aberrations; Transsexualism; Turner Syndrome; Virilism

Topics: 17-Ketosteroids; Adult; Androgens; Androstanes; Biopsy; Cheek; Chorionic Gonadotropin; Follicle Stimulating Hormone; Gonadotropins; Humans; Karyotyping; Klinefelter Syndrome; Leydig Cells; Luteinizing Hormone; Male; Middle Aged; Mosaicism; Sex Chromosomes; Skin; Testis; Testosterone

Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Androgen-Insensitivity Syndrome; Castration; Feedback; Humans; Hypogonadism; Klinefelter Syndrome; Leydig Cells; Male; Testis; Testosterone

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Delusions; Humans; Karyotyping; Klinefelter Syndrome; Male; Schizophrenia; Schizophrenic Psychology

The mean basal plasma testosterone level in 28 patients with chromatin positive Klinefelter's syndrome was significantly lower than in 58 healthy male controls. In 12 of the patients the hormone levels were in the normal range. In both the eugonadal males and the Klinefelter patients the plasma testosterone levels spontaneously decreased throughout the day, the relative decrease in both groups being of the same order of magnitude. Short term ACTH infusion and the administration of dexamethasone did not significantly influence the plasma testosterone concentration in the Klinefelter patients. These findings do not support the view that the adrenal cortex plays a major role in contributing to the circulating plasma testosterone levels in this syndrome.

Topics: 11-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Cortex; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Circadian Rhythm; Depression, Chemical; Dexamethasone; Humans; Klinefelter Syndrome; Male; Middle Aged; Stimulation, Chemical; Testosterone

Two cases with long Y chromosome in a father and his son have been described. The chromosomes were analysed routinely using the peripheral blood leukocyte culture according to Moorhead et al. (1960) and of the slightly modified fluorescence method of Caspersson (1970, 1971) after QM-staing. In both patients the size of the Y resembled that of the pair 17--18 of autosomes. A brightly fluorescent heterochromatic region of the Y showed normal patterns and size. In one of the patients the analysis of solar and palmar dermatoglyphics, the testicular biopsy, EEG, glucose loading test, as well as laboratory tests evaluating the hormonal function of adrenal cortex and of thyroid gland were performed. The second patient did not agree to any tests.

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Glands; Adult; Fluorescence; Humans; Karyotyping; Klinefelter Syndrome; Male; Sex Chromosomes; Thyroid Gland

Topics: 17-Ketosteroids; Crime; Criminal Psychology; Cytogenetics; Dermatoglyphics; Diseases in Twins; Female; Gonadotropins, Pituitary; Gynecomastia; Humans; Karyotyping; Klinefelter Syndrome; Male; Memory; Mental Disorders; Middle Aged; Mosaicism; Penis; Pregnancy; Sex Chromatin; Testis; Triplets; Twins

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Body Height; Body Weight; Child, Preschool; Dermatoglyphics; Fibroblasts; Genes; Humans; Infant; Infant, Newborn; Karyotyping; Klinefelter Syndrome; Lymphocytes; Male; Microscopy, Fluorescence; Sex Chromatin

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adult; Biopsy; Cytogenetics; Female; Germ Cells; Humans; Intellectual Disability; Intelligence Tests; Klinefelter Syndrome; Male; Maternal Age; Puberty; Testis

Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adult; Androsterone; Dehydroepiandrosterone; Dexamethasone; Estradiol; Estrone; Etiocholanolone; Female; Humans; Klinefelter Syndrome; Male; Middle Aged

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Chorionic Gonadotropin; Estrogens; Gonadotropin-Releasing Hormone; Gonadotropins, Pituitary; Humans; Insulin; Karyotyping; Klinefelter Syndrome; Luteinizing Hormone; Male; Pituitary Gland; Sex Chromatin; Sex Chromosomes; Somatotypes; Testis; Testosterone

Topics: 17-Ketosteroids; Aged; Biopsy; Breast Neoplasms; Estrogens; Gonadotropins; Humans; Karyotyping; Klinefelter Syndrome; Male; Sex Chromatin; Sex Chromosomes; Testis

Topics: 17-Ketosteroids; Acne Vulgaris; Adult; Humans; Klinefelter Syndrome; Male; Testosterone

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acromegaly; Adolescent; Adult; Androsterone; Chorionic Gonadotropin; Dehydroepiandrosterone; Endocrine System Diseases; Estrogens; Etiocholanolone; Humans; Hypogonadism; Hypopituitarism; Klinefelter Syndrome; Male; Metabolism; Middle Aged; Pregnanetriol; Puberty; Testosterone

Topics: 17-Ketosteroids; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Adult; Aged; Alcohols; Amenorrhea; Androsterone; Carcinoma; Child, Preschool; Chromatography, Gas; Cushing Syndrome; Dehydroepiandrosterone; Etiocholanolone; Female; Genital Diseases, Male; Hirsutism; Humans; Hyperplasia; Hyperthyroidism; Hypospadias; Infant; Infertility, Male; Klinefelter Syndrome; Lactation Disorders; Male; Middle Aged; Polycystic Ovary Syndrome; Pregnancy; Pregnanetriol

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Addison Disease; Administration, Oral; Adolescent; Adult; Aged; Androstanes; Biological Assay; Body Weight; Cortisone; Dexamethasone; Female; Gonadotropins; Humans; Hydrocortisone; Hypogonadism; Injections, Intravenous; Klinefelter Syndrome; Male; Metyrapone; Middle Aged; Obesity; Radioisotope Dilution Technique; Testosterone; Time Factors

Topics: 17-Ketosteroids; Biopsy; Carbon Isotopes; Estradiol; Estrone; Female; Gonadotropins; Humans; Hydroxyprogesterones; In Vitro Techniques; Klinefelter Syndrome; Male; Testis; Testosterone; Tritium

Topics: 17-Ketosteroids; Body Weight; Chromosome Aberrations; Cytogenetics; Dermatoglyphics; Estrogens; Gynecomastia; Humans; Intellectual Disability; Karyotyping; Klinefelter Syndrome; Male; Mosaicism; Puberty

Topics: 17-Ketosteroids; Adolescent; Adult; Biopsy; Humans; Klinefelter Syndrome; Leydig Cells; Male; Middle Aged; Testis; Testosterone

Topics: 17-Ketosteroids; Addison Disease; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Glands; Adrenal Insufficiency; Adrenocorticotropic Hormone; Anorexia Nervosa; Cushing Syndrome; Diagnosis, Differential; Female; Fluorometry; Hirsutism; Humans; Hypopituitarism; Injections, Intravenous; Klinefelter Syndrome; Male; Methods; Obesity; Pituitary Neoplasms; Spectrophotometry; Turner Syndrome

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Glands; Adult; Age Factors; Behavior; Bone Development; Child; Humans; Injections, Intramuscular; Klinefelter Syndrome; Male; Pregnanetriol; Projective Techniques; Testosterone

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Age Factors; Androgens; Androsterone; Child; Chromatography, Gas; Dehydroepiandrosterone; Dexamethasone; Etiocholanolone; Gonadotropins; Humans; Infant; Klinefelter Syndrome; Male; Pregnanediol; Pregnanes; Pregnanetriol; Testosterone

Topics: 17-Ketosteroids; Biopsy; Cryptorchidism; Erectile Dysfunction; Gonadotropins; Humans; Infertility, Male; Klinefelter Syndrome; Male; Semen; Sex Chromatin; Spermatozoa; Testicular Diseases

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aged; Breast Neoplasms; Humans; Klinefelter Syndrome; Male; Middle Aged

Topics: 17-Ketosteroids; Adolescent; Adult; Aged; Androsterone; Autoantibodies; Biopsy; Body Constitution; Cytogenetics; Female; Genetics, Medical; Gonadotropins, Pituitary; Gynecomastia; Hair; Humans; Karyotyping; Klinefelter Syndrome; Male; Maternal Age; Middle Aged; Mosaicism; Mouth Mucosa; Sex Chromosome Aberrations; Testis; Tritium

Topics: 17-Ketosteroids; Adult; Gonadotropins, Pituitary; Humans; Karyotyping; Klinefelter Syndrome; Male; Mosaicism; Phenotype; Semen; Sex Chromatin; Testis; Vas Deferens

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenocarcinoma, Mucinous; Aged; Atrophy; Breast Neoplasms; Estrogens; Gynecomastia; Humans; Karyotyping; Klinefelter Syndrome; Male; Prostate

Topics: 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Alopecia; Androstanes; Breast Diseases; Chemistry, Clinical; Chorionic Gonadotropin; Chromatography, Paper; Dehydroepiandrosterone; Dermatitis, Seborrheic; Female; Follicle Stimulating Hormone; Humans; Klinefelter Syndrome; Male; Middle Aged; Radiation Injuries; Testis; Testosterone

Topics: 17-Ketosteroids; Androgens; Child; Child, Preschool; Disorders of Sex Development; Female; Humans; Infant; Infant, Newborn; Klinefelter Syndrome; Male; Pregnanetriol; Progesterone; Sex Determination Analysis; Turner Syndrome

Topics: 17-Ketosteroids; Adult; Androgens; Fructose; Gonadotropins; Humans; Klinefelter Syndrome; Leydig Cells; Male; Semen; Sex Chromatin; Testosterone

Topics: 17-Ketosteroids; Adolescent; Gonadotropins; Humans; Hypospadias; Intellectual Disability; Karyotyping; Klinefelter Syndrome; Male; Sex Chromatin; Testosterone

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adult; Biopsy; Blood Cell Count; Emotions; Estradiol; Estriol; Estrone; Follicle Stimulating Hormone; Humans; Karyotyping; Klinefelter Syndrome; Luteinizing Hormone; Male; Mental Disorders; Mosaicism; Pregnanediol; Pregnanetriol; Sex Chromatin; Testis

Topics: 17-Ketosteroids; Adult; Connective Tissue; Diabetes Complications; Gonadotropins; Humans; Klinefelter Syndrome; Male; Skin; Testis; Werner Syndrome

Topics: 17-Ketosteroids; Androgens; Biopsy; Endocrine System Diseases; Estrogens; Gonadotropins; Humans; Hypogonadism; Klinefelter Syndrome; Male; Testicular Diseases; Testis

Topics: 17-Ketosteroids; Adolescent; Adult; Child; Humans; Klinefelter Syndrome; Male; Sex Chromosomes; Testis

Topics: 17-Ketosteroids; Adolescent; Adult; Amenorrhea; Cytodiagnosis; Diagnosis, Differential; Disorders of Sex Development; Female; Gonadotropins; Humans; Karyotyping; Klinefelter Syndrome; Male; Phenotype; Saliva; Sex Chromatin; Sex Chromosomes; Turner Syndrome

Topics: 17-Ketosteroids; Adult; Glucocorticoids; Glucose Tolerance Test; Humans; Karyotyping; Klinefelter Syndrome; Liver Function Tests; Male

Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Androsterone; Chromatography, Gas; Cushing Syndrome; Dehydroepiandrosterone; Disorders of Sex Development; Etiocholanolone; Female; Hirsutism; Humans; Klinefelter Syndrome; Male; Polycystic Ovary Syndrome; Pregnanediol; Pregnanetriol; Testicular Neoplasms; Turner Syndrome

Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Androgens; Androsterone; Carbon Isotopes; Chorionic Gonadotropin; Dexamethasone; Etiocholanolone; Humans; Hypogonadism; Klinefelter Syndrome; Male; Pituitary-Adrenal Function Tests; Secretory Rate; Testosterone; Tritium

Topics: 17-Ketosteroids; Acromegaly; Adult; Androgens; Chromosome Aberrations; Chromosome Disorders; Disorders of Sex Development; Humans; Hypogonadism; Infertility, Male; Klinefelter Syndrome; Male; Olfaction Disorders; Sella Turcica; Sex Chromatin

Topics: 17-Ketosteroids; Adult; Humans; Klinefelter Syndrome; Male; Mosaicism; Sex Chromatin; Sex Chromosomes

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adult; Diagnosis, Differential; Estrogens; Gonadotropins; Humans; Karyotyping; Klinefelter Syndrome; Male; Sex Chromatin; Sex Chromosome Aberrations; Testis

Topics: 17-Ketosteroids; Adolescent; Adult; Child; Humans; Karyotyping; Klinefelter Syndrome; Male; Sex Chromatin

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adult; Diagnosis, Differential; DNA; Estrogens; Gonadotropins; Humans; Iodine Radioisotopes; Klinefelter Syndrome; Male; Middle Aged; Mosaicism; Sex Chromatin; Testis; Thyroid Function Tests; Urine

Topics: 17-Ketosteroids; Adolescent; Child; Child, Preschool; Chromatography, Paper; Chromosome Aberrations; Chromosome Disorders; Diagnosis, Differential; Disorders of Sex Development; Female; Humans; Infant; Klinefelter Syndrome; Male; Sex Chromatin; Turner Syndrome; Virilism

Topics: 17-Ketosteroids; Adenocarcinoma; Adenocarcinoma, Scirrhous; Adrenal Cortex Hormones; Biopsy; Breast; Breast Neoplasms; Carcinoma, Ductal; Chromosomes; Fluids and Secretions; Gonadotropins; Gynecomastia; Humans; Klinefelter Syndrome; Male; Neoplasm Metastasis; Neoplasms; Pathology; Urine

Topics: 17-Ketosteroids; Acromegaly; Addison Disease; Adenoma; Adolescent; Adrenal Hyperplasia, Congenital; Adult; Blood; Child; Chromatography, Gas; Cushing Syndrome; Female; Glucuronates; Hirsutism; Humans; Hypogonadism; Klinefelter Syndrome; Male; Middle Aged; Polycystic Ovary Syndrome; Testosterone; Urine

Topics: 17-Ketosteroids; Adolescent; Biomedical Research; Child; Gonadotropins; Humans; Intellectual Disability; Iodine Isotopes; Klinefelter Syndrome; Metabolism; Radioisotopes; Radionuclide Imaging; Schizophrenia; Sex Chromosome Aberrations; Sex Chromosome Disorders; Thyroid Function Tests; Thyroid Gland; Thyrotropin; Urine

Topics: 17-Ketosteroids; Addison Disease; Adrenal Insufficiency; Chorionic Gonadotropin; Erectile Dysfunction; Gonadotropins; Humans; Hypoadrenocorticism, Familial; Hypogonadism; Klinefelter Syndrome; Male; Steroids

Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Androgen-Insensitivity Syndrome; Androgens; Estrogens; Gonadotropins; Humans; Hypogonadism; Klinefelter Syndrome; Male; Turner Syndrome; Urine

Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex; Adrenocorticotropic Hormone; Blood Chemical Analysis; Cushing Syndrome; Dexamethasone; Hydrocortisone; Klinefelter Syndrome; Obesity; Pharmacology; Pituitary-Adrenal Function Tests; Urine

Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Amenorrhea; Chemical Phenomena; Chemistry; Chromatography; Diencephalon; Estrogens; Female; Gonadotropins; Gonadotropins, Pituitary; Hexestrol; Humans; Hypopituitarism; Klinefelter Syndrome; Menstruation; Ovary; Pharmacology; Physiology; Pituitary Gland; Pituitary Neoplasms; Pregnanediol; Turner Syndrome; Urine; Uterine Hemorrhage

Topics: 17-Ketosteroids; Adolescent; Adrenal Gland Neoplasms; Androsterone; Estradiol; Estriol; Estrone; Etiocholanolone; Eunuchism; Gynecomastia; Humans; Klinefelter Syndrome; Male; Steroids; Testicular Neoplasms; Urine