17-ketosteroids and Hypospadias

17-ketosteroids has been researched along with Hypospadias* in 18 studies

Reviews

3 review(s) available for 17-ketosteroids and Hypospadias

ArticleYear
Testicular feminization syndrome: current clinical considerations.
    Urology, 1976, Volume: 7, Issue:6

    The testicular feminization syndrome (TFS) in its complete form results in total feminization due to a nuclear inaction of androgens, and the female role should be supported with postpubertal orchiectomy to avoid the risk of malignancy. Incomplete forms of the syndrome (ITFS) include Type I n which some degree of masculinization may be observed, prompting earlier gonadectomy, and Type II or pseudovaginal perineoscrotal hypospadias (PPSH) which is always characterized by pubertal masculinization, necessitating management and support of these patients as males. Other intersex abnormalities which must be differentiated include true hermaphroditism, the Swyer syndrome, males with 17-ketosteroid reductase deficiency, and Reifenstein's syndrome.

    Topics: 17-Ketosteroids; Adolescent; Adult; Androgen-Insensitivity Syndrome; Androgens; Animals; Child; Diagnosis, Differential; Disorders of Sex Development; Female; Follicle Stimulating Hormone; Humans; Hydroxysteroid Dehydrogenases; Hypospadias; Infertility, Male; Male; Mice; Rats

1976
[Intersexuality in childhood].
    Medizinische Klinik, 1974, Nov-01, Volume: 69, Issue:44

    Topics: 17-Ketosteroids; Adolescent; Adrenal Hyperplasia, Congenital; Androgen-Insensitivity Syndrome; Child; Child, Preschool; Chorionic Gonadotropin; Diagnosis, Differential; Disorders of Sex Development; Female; Genetic Counseling; Genitalia, Female; Genitalia, Male; Humans; Hypospadias; Infant; Klinefelter Syndrome; Male; Mosaicism; Pregnanetriol; Progesterone; Psychosexual Development; Sex Chromosome Aberrations; Transsexualism; Turner Syndrome; Virilism

1974
Differential diagnosis of genital ambiguity in the newborn.
    Clinical obstetrics and gynecology, 1972, Volume: 15, Issue:1

    Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Androgen-Insensitivity Syndrome; Diagnosis, Differential; Disorders of Sex Development; Female; Follicle Stimulating Hormone; Genitalia, Female; Genitalia, Male; Gynecomastia; Humans; Hypospadias; Infant; Infant, Newborn; Infant, Newborn, Diseases; Infertility, Male; Karyotyping; Male; Sex Chromatin; Sex Determination Analysis; Testosterone; Virilism

1972

Other Studies

15 other study(ies) available for 17-ketosteroids and Hypospadias

ArticleYear
Familial male pseudohermaphroditism with incomplete virilization.
    Obstetrics and gynecology, 1978, Volume: 51, Issue:1 Suppl

    A 21-year-old 46 XY individual with familial male pseudohermaphroditism was investigated. Phenotype consisted of pseudovaginal perineoscrotal hypospadias with bilateral inguinal gonads and a masculine habitus without gynecomastia. Plasma testosterone, cortisol, follicle stimulating hormone, urinary 17-ketosteroids, and 17-ketogenic steroids were within the normal male range. Plasma dihydrotestosterone was at the lower limit of the normal male range. Plasma luteinizing hormone was three times and plasma estradiol was about one and a half times the upper limit of normal for men. These results are consistent with a partial defect in the mechanism of action of testosterone. The differential diagnosis of various forms of male pseudohermaphroditism is discussed.

    Topics: 17-Ketosteroids; Adult; Dihydrotestosterone; Disorders of Sex Development; Estradiol; Follicle Stimulating Hormone; Humans; Hydrocortisone; Hypospadias; Luteinizing Hormone; Male; Pedigree; Phenotype; Testosterone; Virilism

1978
Response to LH-RH and HCG in two brothers with the Reifenstein syndrome.
    Helvetica paediatrica acta, 1976, Volume: 30, Issue:4-5

    Two brothers with Reifenstein syndrome underwent LH-RH and HCG tests at various ages ranging from 13 to 17 years. We found that at age 13 the plasma LH and FSH response to one LH-RH injection was normal. After the age of 14, the basal plasma concentration of LH and FSH and their response to LH-RH became elevated. Concomitantly the plasma testosterone levels rose to abnormal levels. These findings are compatible with progressive development of primary gonadal dysfunction and with peripheral insensitivity to testosterone.

    Topics: 17-Ketosteroids; Adolescent; Chorionic Gonadotropin; Disorders of Sex Development; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Gynecomastia; Humans; Hypospadias; Infertility, Male; Luteinizing Hormone; Male; Puberty; Testosterone

1976
Intersex states in young children: the importance of radiology in making a correct diagnosis.
    Clinical radiology, 1974, Volume: 25, Issue:1

    Topics: 17-Ketosteroids; Adrenal Glands; Catheterization; Child; Child, Preschool; Disorders of Sex Development; Endoscopy; Female; Gonads; Humans; Hydrocortisone; Hyperplasia; Hypospadias; Hysterosalpingography; Infant; Infant, Newborn; Karyotyping; Male; Ovary; Sex Chromatin; Sex Determination Analysis; Testis; Turner Syndrome; Urinary Bladder; Vagina

1974
A case of true hermaphroditism with impaired growth and normal growth hormone levels in a Chinese.
    The Medical journal of Australia, 1973, Jul-07, Volume: 2, Issue:1

    Topics: 17-Ketosteroids; Adolescent; Castration; Disorders of Sex Development; Female; Growth Disorders; Growth Hormone; Gynecomastia; Humans; Hypospadias; Hysterectomy

1973
Studies on the inhibition of fetal androgen formation. Inhibition of testosterone synthesis in rat and rabbit fetal testes with observations on reproductive tract development.
    Endocrinology, 1971, Volume: 89, Issue:1

    Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Abnormalities, Drug-Induced; Androstanes; Animals; Carbon Isotopes; Cholestanes; Chromatography, Paper; Chromatography, Thin Layer; Crystallization; Dehydroepiandrosterone; Depression, Chemical; Female; Fetus; Genitalia, Male; Hydroxyprogesterones; Hydroxysteroid Dehydrogenases; Hypospadias; In Vitro Techniques; Indenes; Male; Perineum; Pregnancy; Pregnenolone; Pyridines; Rabbits; Rats; Testis; Testosterone; Wolffian Ducts

1971
The determination of urinary pregnanetriol and the neutral 17-ketosteroids by gas-liquid chromatography.
    Steroids, 1971, Volume: 18, Issue:2

    Topics: 17-Ketosteroids; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Adult; Aged; Alcohols; Amenorrhea; Androsterone; Carcinoma; Child, Preschool; Chromatography, Gas; Cushing Syndrome; Dehydroepiandrosterone; Etiocholanolone; Female; Genital Diseases, Male; Hirsutism; Humans; Hyperplasia; Hyperthyroidism; Hypospadias; Infant; Infertility, Male; Klinefelter Syndrome; Lactation Disorders; Male; Middle Aged; Polycystic Ovary Syndrome; Pregnancy; Pregnanetriol

1971
Androgenicity in the rat fetus of metabolites of testosterone and antagonism by cyproterone acetate.
    Endocrinology, 1971, Volume: 89, Issue:1

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Analysis of Variance; Androgen Antagonists; Androstanes; Androsterone; Animals; Anthropometry; Body Weight; Dihydrotestosterone; Drug Antagonism; Female; Fetal Diseases; Fetus; Hypospadias; Male; Organ Size; Pregnancy; Pregnancy Complications; Pregnanes; Rats; Sterols; Testosterone; Urethra; Virilism

1971
Hypogonadism in chromatin-negative phenotypic male subjects.
    The Journal of urology, 1970, Volume: 103, Issue:5

    Topics: 17-Ketosteroids; Adolescent; Adult; Color Vision Defects; Disorders of Sex Development; Eunuchism; Follicle Stimulating Hormone; Gynecomastia; Humans; Hypogonadism; Hypospadias; Infertility, Male; Intellectual Disability; Male; Olfaction Disorders; Phenotype; Sex Chromosome Aberrations; Testicular Diseases

1970
[Treatment of the newborn with abnormally developed external genitalia].
    Ginekologia polska, 1970, Volume: 41, Issue:4

    Topics: 17-Ketosteroids; Disorders of Sex Development; Female; Genitalia; Genitalia, Female; Genitalia, Male; Humans; Hypospadias; Infant, Newborn; Male; Turner Syndrome

1970
Hypospadics in Klinefelter's syndrome.
    The Journal of urology, 1968, Volume: 100, Issue:3

    Topics: 17-Ketosteroids; Adolescent; Gonadotropins; Humans; Hypospadias; Intellectual Disability; Karyotyping; Klinefelter Syndrome; Male; Sex Chromatin; Testosterone

1968
[Apropos of a case of intersexual condition recognised at birth; diagnostic and sex determination problems].
    Quaderni di clinica ostetrica e ginecologica, 1967, Volume: 22, Issue:8

    Topics: 17-Ketosteroids; Cryptorchidism; Disorders of Sex Development; Humans; Hypospadias; Infant, Newborn; Karyotyping; Male; Sex Chromatin; Sex Chromosomes; Sex Determination Analysis

1967
[On the problems of pseudohermaphroditism].
    Wiener medizinische Wochenschrift (1946), 1967, Jun-24, Volume: 117, Issue:25

    Topics: 17-Ketosteroids; Adolescent; Adrenal Hyperplasia, Congenital; Disorders of Sex Development; Female; Humans; Hypospadias; Infant; Male

1967
PATHOLOGIC AND CYTOGENETIC FINDINGS IN TRUE HERMAPHRODITISM; REPORT OF 6 CASES AND REVIEW OF 23 CASES FROM THE LITERATURE.
    Obstetrics and gynecology, 1965, Volume: 25

    Topics: 17-Ketosteroids; Adolescent; Cell Biology; Child; Chromosome Aberrations; Chromosome Disorders; Cytogenetic Analysis; Disorders of Sex Development; Female; Genitalia; Humans; Hypospadias; Infant; Infant, Newborn; Male; Mosaicism; Ovary; Ovotesticular Disorders of Sex Development; Pathology; Sex Chromatin; Testis; Urine

1965
STUDY OF DELTA-5, 3-BETA-HYDROXYSTEROID DEHYDROGENASE IN NORMAL, HYPERPLASTIC AND NEOPLASTIC ADRENAL CORTICAL TISSUE.
    The Journal of clinical endocrinology and metabolism, 1964, Volume: 24

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; 3-Hydroxysteroid Dehydrogenases; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Child; Dehydroepiandrosterone; Estriol; Histocytochemistry; Humans; Hydroxysteroid Dehydrogenases; Hyperplasia; Hypospadias; Infant; Infant, Newborn; Male; Mixed Function Oxygenases; Pathology; Testis; Urine

1964
[CLINICAL STUDIES ON TESTICULAR HYPOFUNCTION. (I. PHYSICAL ASPECTS)].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1963, Volume: 54

    Topics: 17-Ketosteroids; Acid Phosphatase; Adolescent; Alkaline Phosphatase; Bone and Bones; Congenital Abnormalities; Embryology; Gonadotropins; Growth; Humans; Hypogonadism; Hypospadias; Male; Obesity; Physiology; Puberty; Sexual Maturation; Testis

1963