17-ketosteroids and Growth-Disorders

17-ketosteroids has been researched along with Growth-Disorders* in 25 studies

Trials

1 trial(s) available for 17-ketosteroids and Growth-Disorders

ArticleYear
Effectiveness of long-term human growth hormone therapy for short stature in children with growth hormone deficiency.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 30, Issue:1

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Age Determination by Skeleton; Antibody Formation; Blood Proteins; Body Height; Body Weight; Child; Child, Preschool; Clinical Trials as Topic; Female; Follow-Up Studies; Growth; Growth Disorders; Growth Hormone; Humans; Hypopituitarism; Insulin; Iodine; Long-Term Care; Male; Metyrapone; Pituitary Function Tests; Protein Binding; Radioimmunoassay; Skinfold Thickness

1970

Other Studies

24 other study(ies) available for 17-ketosteroids and Growth-Disorders

ArticleYear
Acute and chronic effects of human recombinant GH (hrGH) on adrenal steroidogenesis in children affected with isolated GH deficiency (IGHD).
    The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:7

    In a previous study we demonstrated that, in children affected with isolated GH deficiency, an acute high-dose human recombinant GH (hrGH) treatment increases the 11-deoxycortisol and induces an IGF-I responsiveness to ACTH. The aim of the present study was to reevaluate, in the same children, the adrenal and IGF-I responsiveness to ACTH after a chronic replacement-dose GH therapy. Ten children (seven males and three females, mean age 7 years) affected with isolated GH deficiency underwent a synthetic ACTH 1-17 test before and after sc administration of human recombinant GH at a dose of 0.6 UI/kg/week for 3 months. After therapy, the 11-deoxycortisol responsiveness to ACTH significantly decreased compared with that observed after acute treatment (P < 0.001), and so it returned to baseline. No differences were detected in the responsiveness to ACTH of cortisol, dehydroepiandrosterone-sulphate, D4-androstenedione, and 17-hydroxyprogesterone. On the other hand, the chronic treatment induced an IGF-I responsiveness to ACTH (P < 0.001). In conclusion, our study demonstrates that, in isolated GH deficiency, replacement doses of hrGH do not modify the adrenal steroid basal levels or its responsiveness to ACTH, whereas both replacement and high doses of hrGH induce an IGF-I responsiveness to ACTH.

    Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Body Height; Body Weight; Child; Child, Preschool; Cohort Studies; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Growth Disorders; Growth Hormone; Humans; Male; Peptide Fragments; Recombinant Proteins; Reference Values

1995
Effect of human growth hormone on adrenal androgens in children with growth hormone deficiency.
    Hormone research, 1984, Volume: 20, Issue:3

    The effect of human growth hormone (hGH) on adrenal androgen secretion was assessed in 7 patients (5 males, 2 females) with GH deficiency but normal ACTH-cortisol function. Patients ranged in age from 9 5/12 to 14 8/12 years (median 12 years). Plasma concentrations of dehydroepiandrosterone-sulfate (DHEA-S) and urinary excretion of 17-ketosteroids (17-KS) and free cortisol were determined before, during short-term (2 U/day X 3) and after long-term (6 months) treatment with hGH. No significant change was noted in the plasma concentration or urinary excretion of steroids during the short-term administration of hGH. Despite a significant increase in growth velocity during 6 months of hGH therapy (8.2 vs. 4.5 cm/year, p less than 0.01), the plasma concentrations of DHEA-S and the urinary 17-KS and free cortisol levels were unchanged. These results fail to substantiate a role for hGH in the physiologic control of adrenal androgen secretion. Thus, the low plasma levels of adrenal androgens sometimes seen in GH-deficient patients are not due to the absence of GH per se.

    Topics: 17-Ketosteroids; Adolescent; Adrenal Glands; Androgens; Child; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Female; Growth Disorders; Growth Hormone; Humans; Hydrocortisone; Male; Time Factors

1984
[Gas-chromatographic analysis of estrogens and 17-ketosteroids in the urinary excreta of subnormal subjects, as further confirmation of prior studies made to define the neutral age of the child].
    Minerva pediatrica, 1980, Apr-30, Volume: 32, Issue:8

    Topics: 17-Ketosteroids; Adolescent; Age Factors; Child; Endocrine Glands; Estrogens; Growth Disorders; Humans; Intellectual Disability

1980
[Auxological problems in a case of virilizing adenoma of the adrenal gland].
    Minerva pediatrica, 1977, Mar-24, Volume: 29, Issue:10

    Topics: 17-Ketosteroids; Adenoma; Adrenal Gland Neoplasms; Child; Child, Preschool; Dexamethasone; Growth Disorders; Humans; Hydrocortisone; Male; Metyrapone; Puberty, Precocious

1977
X-linked ichthyosis, bilateral cryptorchidism, hypogenitalism and mental retardation in two siblings.
    Clinical genetics, 1976, Volume: 9, Issue:3

    Two brothers showed ichthyosis, bilateral cryptorchidism, hypogenitalism and mental retardation. In addition, the younger brother had short stature associated with disorders of secretions of insulin, ACTH and GH. This is the third reported case of the syndrome of ichthyosis and hypogonadism.

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Child, Preschool; Cryptorchidism; Follicle Stimulating Hormone; Growth Disorders; Growth Hormone; Humans; Hypogonadism; Ichthyosis; Insulin; Intellectual Disability; Luteinizing Hormone; Male; Thyrotropin

1976
[Examination of the 17-ketosteroid spectrum in children and adolescents by means of paper chromatography (author's transl)].
    Casopis lekaru ceskych, 1976, Oct-29, Volume: 115, Issue:42-43

    Topics: 17-Ketosteroids; Adolescent; Age Factors; Child; Child, Preschool; Chromatography, Paper; Female; Growth Disorders; Humans; Infant; Male; Puberty

1976
Short stature as the only clinical sign of Cushing's syndrome.
    The Journal of pediatrics, 1975, Volume: 86, Issue:1

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Body Height; Cushing Syndrome; Dexamethasone; Diagnosis, Differential; Glucose Tolerance Test; Growth Disorders; Humans; Hydrocortisone; Male; Pyrones; Stimulation, Chemical

1975
Growth retardation in the Lesch-Nyhan syndrome.
    Acta endocrinologica, 1974, Volume: 75, Issue:1

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Age Determination by Skeleton; Arginine; Body Height; Body Weight; Child; Gonadotropins; Growth Disorders; Growth Hormone; Humans; Immunoassay; Insulin; Lesch-Nyhan Syndrome; Male; Radioimmunoassay; Somatomedins; Stimulation, Chemical; Testosterone; Thyroid Function Tests

1974
Endocrine function in thalassemia major.
    Annals of the New York Academy of Sciences, 1974, Volume: 232, Issue:0

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adult; Age Determination by Skeleton; Aldosterone; Anemia, Sickle Cell; Blood Transfusion; Child; Erythrocyte Count; Female; Growth Disorders; Growth Hormone; Hematocrit; Hemoglobins; Humans; Male; Pituitary-Adrenal Function Tests; Puberty; Radioimmunoassay; Splenectomy; Thalassemia; Thyroid Function Tests

1974
Improvement of adult height prognosis in precocious puberty by cyproterone acetate.
    Acta paediatrica Scandinavica, 1973, Volume: 62, Issue:4

    Topics: 17-Ketosteroids; Age Determination by Skeleton; Androgen Antagonists; Body Height; Bone Development; Child; Child, Preschool; Cyproterone; Estrogens; Female; Gonadotropins; Growth Disorders; Humans; Male; Pregnadienes; Prognosis; Puberty, Precocious

1973
Iatrogenic Cushing's disease in a boy after misdiagnosis of salt-losing virilizing adrenal hyperplasia: impaired metyrapone response with failure of catch-up growth.
    The Journal of pediatrics, 1973, Volume: 83, Issue:1

    Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Adrenocorticotropic Hormone; Body Weight; Bone Development; Child; Child, Preschool; Cushing Syndrome; Desoxycorticosterone; Diagnosis, Differential; Diagnostic Errors; Fludrocortisone; Glucocorticoids; Growth Disorders; Growth Hormone; Humans; Hydrocortisone; Infant; Infant, Newborn; Insulin; Male; Methylprednisolone; Metyrapone; Mineralocorticoids; Pituitary-Adrenal Function Tests

1973
[Clinical and hormonal characteristics of retardation of sexual development in girls].
    Akusherstvo i ginekologiia, 1973, Volume: 49, Issue:1

    Topics: 17-Ketosteroids; Adolescent; Chorionic Gonadotropin; Disorders of Sex Development; Female; Gonadal Steroid Hormones; Growth Disorders; Humans; Hypogonadism; Ovary; Pituitary-Adrenal Function Tests; Sex Chromatin

1973
A case of true hermaphroditism with impaired growth and normal growth hormone levels in a Chinese.
    The Medical journal of Australia, 1973, Jul-07, Volume: 2, Issue:1

    Topics: 17-Ketosteroids; Adolescent; Castration; Disorders of Sex Development; Female; Growth Disorders; Growth Hormone; Gynecomastia; Humans; Hypospadias; Hysterectomy

1973
Nyctohemeral growth hormone levels in children with growth retardation and inflammatory bowel disease.
    Gut, 1973, Volume: 14, Issue:3

    Short stature is a common complication of inflammatory bowel disease. Recently McCaffery, Nasr, Lawrence, and Kirsner (1970) concluded, from blood growth hormone (GH) levels obtained during insulin-hypoglycaemic provocation, that GH deficiency contributed to the retardation in growth observed in subjects with inflammatory bowel disease. Although it was not possible to eliminate the possibility of partial hypopituitarism, this study does not confirm the existence of GH deficiency in six subjects with short stature complicating inflammatory bowel disease. The nyctohemeral (night and day) serum GH is described, and the insulin and glucose levels in these subjects and normal sleep-related GH rises in all are demonstrated. This finding is not compatible with growth hormone deficiency. In one subject the response to arginine provocation was blunted. Three subjects manifested hyperinsulinism and evidence for ;insulin resistance'. These findings are unexplained but suggest that insulin resistance may contribute to a blunted GH response to insulin-induced hypoglycaemia. Blunted GH response to both arginine and insulin-induced hypoglycaemia may also result from continuous secretion and reduced pituitary storage of growth hormone. This possibility is suggested by the pattern of raised blood GH levels in one of the subjects.

    Topics: 17-Ketosteroids; Adolescent; Animals; Arginine; Blood Glucose; Child; Circadian Rhythm; Colitis, Ulcerative; Crohn Disease; Female; Gonadotropins, Pituitary; Growth Disorders; Growth Hormone; Humans; Insulin; Male; Sheep; Thyroid Function Tests

1973
Failure of catch-up growth after Cushing's syndrome in childhood.
    American journal of diseases of children (1960), 1972, Volume: 124, Issue:2

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenalectomy; Adrenocorticotropic Hormone; Basal Metabolism; Child; Cushing Syndrome; Female; Fludrocortisone; Growth Disorders; Growth Hormone; Humans; Hydrocortisone; Thyroxine

1972
Biochemical and endocrinological studies in parasite-infested patients with and without infantilism.
    Acta paediatrica Academiae Scientiarum Hungaricae, 1972, Volume: 13, Issue:4

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Blood Glucose; Child; Estrogens; Gonadotropins; Growth Disorders; Hepatomegaly; Humans; Hydrocortisone; Hypoglycemia; Hypogonadism; Intellectual Disability; Liver Diseases, Parasitic; Liver Function Tests; Male; Middle Aged; Nutrition Disorders; Pituitary-Adrenal Function Tests; Pituitary-Adrenal System; Schistosomiasis; Splenomegaly; Stimulation, Chemical

1972
Syndrome of growth resistance, obesity, and intellectual impairment with precocious puberty.
    Archives of disease in childhood, 1972, Volume: 47, Issue:251

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Abnormalities, Multiple; Body Height; Body Weight; Child; Estrogens; Female; Gonadotropins; Growth Disorders; Growth Hormone; Humans; Hypogonadism; Intellectual Disability; Metyrapone; Obesity; Puberty, Precocious

1972
Pituitary function in the deprivation syndrome.
    The Journal of pediatrics, 1971, Volume: 79, Issue:2

    Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Blood Glucose; Body Height; Body Weight; Child; Child, Preschool; Growth; Growth Disorders; Growth Hormone; Humans; Hydrocortisone; Infant; Infant Nutrition Disorders; Insulin; Maternal Deprivation; Nutrition Disorders; Pituitary Gland; Psychosocial Deprivation; Thyroid Function Tests

1971
[Gonadal dysgenesis with ring-shaped chromosome in an adolescent girl].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1971, Dec-20, Volume: 47, Issue:52

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Amenorrhea; Cell Division; Chromatography, Gas; Chromosome Aberrations; Dermatoglyphics; Estrogens; Female; Glucose Tolerance Test; Growth Disorders; Humans; Karyotyping; Sex Chromosomes; Turner Syndrome

1971
[Diagnostic value of metabolic tests following administration of human growth hormone in the assessment of hypothalamo-hypophyseal dwarfism in children].
    Pediatria polska, 1971, Volume: 46, Issue:6

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Child; Dwarfism, Pituitary; Female; Growth Disorders; Growth Hormone; Humans; Male; Nitrogen

1971
Coexisting anterior pituitary and neurohypophyseal insufficiency. A syndrome with diagnostic implication.
    Archives of internal medicine, 1969, Volume: 123, Issue:4

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Biopsy; Brain Neoplasms; Cholesteatoma; Cortisone; Craniopharyngioma; Diabetes Insipidus; Female; Follicle Stimulating Hormone; Growth Disorders; Hair; Humans; Hypertonic Solutions; Hypogonadism; Hypopituitarism; Hypothalamus; Male; Metyrapone; Middle Aged; Pinealoma; Pituitary Diseases; Polyuria; Radiography; Sella Turcica; Skull; Testis; Thirst; Thyroid Function Tests; Visual Fields; Water

1969
[Clinical investigation on human growth hormone secretion in hypothalamo-pituitary and thyroid diseases].
    Nihon Naibunpi Gakkai zasshi, 1969, Sep-20, Volume: 45, Issue:6

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acromegaly; Adolescent; Adrenocorticotropic Hormone; Adult; Blood Glucose; Child; Child, Preschool; Dwarfism, Pituitary; Electrophoresis; Female; Gonadotropins; Growth Disorders; Growth Hormone; Humans; Hyperthyroidism; Hypopituitarism; Hypothyroidism; Insulin; Ion Exchange Resins; Male; Pituitary Diseases; Radioimmunoassay; Thyroid Diseases; Thyrotropin; Time Factors

1969
Renal transplants in children.
    Transplantation proceedings, 1969, Volume: 1, Issue:1

    Topics: 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Azathioprine; Child; Epiphyses, Slipped; Female; Glomerulonephritis; Growth Disorders; Growth Substances; Histocompatibility Testing; Humans; Hypertension; Hypoglycemia; Immunosuppression Therapy; Insulin; Kidney; Kidney Transplantation; Male; Prednisone; Proteinuria; Social Adjustment; Transplantation Immunology; Transplantation, Homologous

1969
Growth retardation in thalassemia major.
    Annals of the New York Academy of Sciences, 1969, Nov-20, Volume: 165, Issue:1

    Topics: 17-Ketosteroids; Adolescent; Adrenal Glands; Adult; Blood Transfusion; Child; Female; Gonadotropins, Pituitary; Growth; Growth Disorders; Hemosiderosis; Humans; Hypogonadism; Iron; Male; Menstruation Disturbances; Metyrapone; Pituitary Function Tests; Splenectomy; Thalassemia; Thyroid Gland

1969