17-ketosteroids and Genital-Diseases--Female

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Cervix Mucus; Coitus; Female; Fertility; Follicle Stimulating Hormone; Genital Diseases, Female; Humans; Hysterosalpingography; Infertility, Female; Luteal Phase; Male; Menstruation Disturbances; Methods; Ovulation Detection; Pregnancy; Pregnancy Complications; Prolactin; Spermatozoa

Topics: 17-Ketosteroids; Adolescent; Androgens; Child; Child, Preschool; Cortisone; Estrogens; Female; Follicle Stimulating Hormone; Genital Diseases, Female; Genitalia, Female; Gonadotropins, Pituitary; Hormones; Humans; Hydrocortisone; Luteinizing Hormone; Menstruation; Puberty; Radioimmunoassay; Sex Characteristics; Thyroid Hormones

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Female; Genital Diseases, Female; Humans; Ovarian Diseases; Virilism

Topics: 17-Ketosteroids; Androstenedione; Estrogens; Female; Follicle Stimulating Hormone; Genital Diseases, Female; Gonadal Steroid Hormones; Gonadotropins, Pituitary; Humans; Luteinizing Hormone; Methods; Progesterone; Testosterone

Topics: 17-Ketosteroids; Abortion, Habitual; Abortion, Threatened; Ambulatory Care; Diethylstilbestrol; Endocrine System Diseases; Female; Genital Diseases, Female; Humans; Maternal Health Services; Methods; Pregnancy; Progesterone; Somatotypes; Ukraine

Topics: 17-Ketosteroids; Adult; Androgens; Androsterone; Arteriosclerosis; Chromatography, Thin Layer; Coronary Disease; Dehydroepiandrosterone; Estradiol; Estriol; Estrogens; Estrone; Etiocholanolone; Female; Genital Diseases, Female; Humans; Hydroxycorticosteroids; Leiomyoma; Menstruation Disturbances; Middle Aged; Ovarian Diseases; Parametritis; Uterine Neoplasms

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Castration; Chorionic Gonadotropin; Estradiol; Estriol; Estrogens; Estrone; Female; Genital Diseases, Female; Humans; Stimulation, Chemical; Vaginal Smears

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Clitoris; Dexamethasone; Disorders of Sex Development; Dysgerminoma; Estrogens; Female; Fluoxymesterone; Genital Diseases, Female; Gonadotropins; Humans; Hyperplasia; Ovarian Neoplasms; Pituitary-Adrenal Function Tests; Testosterone

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Androstenols; Estrogens; Female; Follicle Stimulating Hormone; Genital Diseases, Female; Hirsutism; Hormones; Humans; Hyperplasia; Luteinizing Hormone; Pregnancy; Pregnancy Complications; Pregnanediol; Testosterone

Several steroid and gonadotropin determinations that are available to practicing physicians are discussed and their practical uses are emphasized. Before undertaking a workup of a patient who appears to have an endocrine abnormality a physician should know the availability and benefits of such tests, the time and expense involved, and the interpretation of laboratory reports. Estrogens are phenolic steroids secreted by the ovaries, adrenal glands, testicles, and the fetal-placental unit and are found in over 20 metabolites in the urine; the most important are estrone, estridiol, and estriol. Total or fractional determinations of urinary estrogens are expensive and may require 7 days. Human gonadotropin determinations are expensive and require 2 weeks. Contraceptive medications, tranquilizers, and sedatives interfere with secretion of this hormone. Clinical usefulness is of value only when dterminations are extremely high or repeatedly ver y low. Culdoscopic findings may be of more value than either estrogen or gonadotrpin determination. Estrogen determinations can be of value in male patients with gynecomastia, in suspected fetal distress or fetal death in utero (a drop of 50% in the normal 1000-fold increase of pregnancy indicates need for delivery of infant), and when an indication of size of infant is needed to determine elective repeat ceasarean sectton. Ther is no practical value of pregnanediol determination in pregnancy or in the amenorrheic female. The clinical use of 17-hydroxycorticoids is related to its value as a screening procedure for adrenal disorders. Patient stress and several drugs may interfere with accurate tests. The 17-ketosteroids are used primarily for the sam e purpose. Progesterone determinations are useful to differentiate ovarian from adrenal pathology. Urinary testosterone increase may be present in some ovarian tumors. Human chorionic gonadotropin (HCG) detection is used for pregnancy tests; a sensitive technique may obtain a positive test day Day 30 of the menstrual cycle or 16 days after conception. These tests are also used in the diagnosis of hydatidiform mole, choriocarcinoma, and to guide care of trophoblastic disease. Of newer methods the competitive protein binding technique for estrogen, progesterone, and testosterone is rapid, accurate, and sensitive. Radioimmunoassay for FSH, LH, and other trophic hormones is complex but promising. Conversion studies are complex but may be of use.

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Chorionic Gonadotropin; Estrogens; Female; Genital Diseases, Female; Gonadotropins; Humans; Methods; Pregnancy; Pregnancy Tests; Pregnanediol; Steroids

Topics: 17-Ketosteroids; Adult; Female; Genital Diseases, Female; Humans; Middle Aged; Vulva

Topics: 17-Ketosteroids; Adolescent; Adrenal Gland Neoplasms; Adult; Female; Genital Diseases, Female; Hirsutism; Humans; Menstruation Disturbances; Ovarian Cysts; Polycystic Ovary Syndrome; Vagina; Vaginal Smears

Topics: 17-Ketosteroids; Amenorrhea; Diagnosis, Differential; Female; Genital Diseases, Female; Gonadotropins; Humans; Pituitary Diseases; Sex Chromosomes; Turner Syndrome

Topics: 17-Ketosteroids; Androgens; Body Fluids; Chromatography, Gas; Endocrine System Diseases; Estrogens; Female; Genital Diseases, Female; Humans; Male; Methods; Pregnanediol; Progesterone; Progestins; Steroids; Testosterone; Urologic Diseases

Topics: 17-Ketosteroids; Female; Genital Diseases, Female; Humans; Inflammation; Methods; Potassium; Prednisolone; Sodium; Water-Electrolyte Balance

Topics: 17-Ketosteroids; Adenocarcinoma; Atrophy; Chorionic Gonadotropin; Clomiphene; Diagnosis; Drug Therapy; Endometriosis; Endometrium; Female; Follicle Stimulating Hormone; Genital Diseases, Female; Gonadotropins; Humans; Hyperplasia; Infertility; Infertility, Female; Ovulation; Pathology; Polycystic Ovary Syndrome; Stilbenes; Toxicology; Urine; Uterine Neoplasms

Topics: 17-Ketosteroids; Acromegaly; Blood; Bone Development; Carbohydrate Metabolism; Child; Genetics, Medical; Genital Diseases, Female; Gigantism; Hepatomegaly; Hirsutism; Humans; Hypertrichosis; Hypertrophy; Infant; Lipodystrophy; Lipodystrophy, Congenital Generalized; Liver Diseases; Metabolism; Muscular Diseases; Radiography

Topics: 17-Ketosteroids; Child; Female; Genital Diseases, Female; Gonadal Steroid Hormones; Gonadotropins; Gonadotropins, Pituitary; Humans; Infant; Infant, Newborn; Puberty; Sexual Maturation; Urinary Tract

Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Baths; Blood Chemical Analysis; Blood Sedimentation; Catecholamines; Female; Genital Diseases, Female; Humans; Humic Substances; Physical Therapy Modalities; Pituitary Gland; Salicylates; Skin; Stress, Physiological

Topics: 17-Ketosteroids; Animals; Female; Genital Diseases, Female; Humans; Mice; Pregnancy; Pregnancy Complications; Rats; Urine

Topics: 17-Ketosteroids; Disease; Female; Genital Diseases, Female; Gynecology; Humans; Ovarian Diseases; Ovary

Topics: 17-Ketosteroids; Body Fluids; Female; Genital Diseases, Female; Humans; Hydrogen-Ion Concentration; Pregnancy; Steroids; Urine

Topics: 17-Ketosteroids; Biological Transport; Body Fluids; Female; Genital Diseases, Female; Humans; Steroids

Topics: 17-Ketosteroids; Female; Genital Diseases, Female; Gynecologic Surgical Procedures; Humans; Steroids; Urine