17-ketosteroids and Diabetes-Insipidus

Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenalectomy; Animals; Breast Neoplasms; Castration; Cortisone; Diabetes Insipidus; Endocrine Glands; Estrogens; Female; Growth Hormone; Humans; Hypophysectomy; Hypothyroidism; Mastectomy; Menopause; Menstruation; Ovary; Prolactin; Protein Binding; Receptors, Cell Surface; Sulfurtransferases; Time Factors

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Blood Glucose; Chlorpropamide; Clinical Trials as Topic; Creatinine; Diabetes Complications; Diabetes Insipidus; Diabetes Mellitus; Female; Humans; Potassium; Sodium; Water

A cyclic excess of cortisol secretion was detected in a patient with diabetes insipidus and diabetes mellitus. The cycles of hypercortisolism were of 7 days' duration, but during the nadir of these cycles urinary excretion of corticosteroids and 17-ketosteroids was within the normal range. The radiological appearance of the sella turcica was normal; however, computerized axial tomography of the head revealed a small tumor immediately superior to the sella turcica. At operation a small chromophobe adenoma superior to the diaphragma sellae and involving the hypophysial stalk was partially resected. Postoperatively, the patient continued to have 7-day cycles of increased corticosteroid excretion, but the amounts excreted were less than they had been preoperatively. Other patients have been described in whom Cushing's disease has been due to cyclic hypercortisolism. These cycles have been remarkably regular in individual patients, but of variable duration in different patients. Furthermore, cyclic hormonogenesis probably occurs in a variety of endocrinopathies. (Neurosurgery, 5: 598--603, 1979).

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma, Chromophobe; Adrenal Cortex; Adult; Cushing Syndrome; Dexamethasone; Diabetes Insipidus; Humans; Hydrocortisone; Male; Periodicity; Pituitary Neoplasms; Vasopressins

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Age Factors; Arginine; Basal Metabolism; Cerebral Ventricle Neoplasms; Child; Child, Preschool; Craniopharyngioma; Diabetes Insipidus; Electrolytes; Female; Gonadotropins; Gonads; Growth Hormone; Humans; Hydrocortisone; Iodine Radioisotopes; Male; Metyrapone; Middle Aged; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Puberty, Precocious; Sex Factors; Thyroid Gland; Water-Electrolyte Balance

Topics: 17-Ketosteroids; Carbamazepine; Diabetes Insipidus; Diabetic Ketoacidosis; Epilepsy; Fluorescence; Fluorometry; Humans; Hydrocortisone; Neuralgia; Potassium; Sodium; Thirst

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Animals; Cerebral Cortex; Cortisone; Creatinine; Diabetes Insipidus; Diencephalon; Diuresis; Dogs; Female; Humans; Hypothalamus; Male; Middle Aged; Pituitary Gland, Posterior; Polyuria; Prednisone; Thirst; Vasopressins; Water-Electrolyte Balance

Topics: 17-Ketosteroids; Adolescent; Dehydroepiandrosterone; Diabetes Insipidus; Estradiol; Feedback; Gynecomastia; Histiocytosis, Langerhans-Cell; Humans; Hypertrophy; Hypothyroidism; Leydig Cells; Male; Puberty; Testicular Diseases; Testosterone

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Blood Glucose; Calcinosis; Dehydration; Diabetes Insipidus; Follicle Stimulating Hormone; Glucose Tolerance Test; Growth Hormone; Humans; Hypopituitarism; Hypothalamus; Insulin; Iodine Isotopes; Luteinizing Hormone; Male; Radiography; Skull; Tuberculosis, Meningeal; Vasopressins

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acromegaly; Addison Disease; Adolescent; Adult; Age Factors; Diabetes Insipidus; Female; Humans; Hypopituitarism; Hypothyroidism; Male; Middle Aged; Pituitary Diseases; Pituitary Neoplasms; Sex Factors

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Biopsy; Brain Neoplasms; Cholesteatoma; Cortisone; Craniopharyngioma; Diabetes Insipidus; Female; Follicle Stimulating Hormone; Growth Disorders; Hair; Humans; Hypertonic Solutions; Hypogonadism; Hypopituitarism; Hypothalamus; Male; Metyrapone; Middle Aged; Pinealoma; Pituitary Diseases; Polyuria; Radiography; Sella Turcica; Skull; Testis; Thirst; Thyroid Function Tests; Visual Fields; Water

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adult; Blood Glucose; Calcium; Cerebrospinal Fluid Rhinorrhea; Cushing Syndrome; Dexamethasone; Diabetes Insipidus; Female; Gonads; Humans; Hyperpituitarism; Male; Meningoencephalitis; Middle Aged; Pituitary Function Tests; Pituitary Irradiation; Pituitary-Adrenal System; Prognosis; Sella Turcica; Yttrium Isotopes

Topics: 17-Ketosteroids; Adolescent; Child; Diabetes Insipidus; Dwarfism; Dwarfism, Pituitary; Humans; Hypothyroidism; Infant; Infant, Newborn; Laurence-Moon Syndrome; Lipodystrophy; Obesity; Pituitary Diseases; Pituitary Gland; Progeria; Puberty; Puberty, Precocious; Sexual Maturation; Urine