17-ketosteroids has been researched along with Carcinoma--Small-Cell* in 2 studies
2 other study(ies) available for 17-ketosteroids and Carcinoma--Small-Cell
| Article | Year |
|---|---|
Ketoconazole. Use in the treatment of ectopic adrenocorticotropic hormone production and Cushing's syndrome in small-cell lung cancer.
Recently, ketoconazole, an imidazole derivative with antifungal properties, has been shown to inhibit adrenal corticosteroid and androgen production. We treated a patient with small-cell lung cancer and Cushing's syndrome secondary to ectopic secretion of adrenocorticotropic hormone in whom it was necessary to discontinue chemotherapy. The patient was treated with ketoconazole, with a resultant reduction in urinary free cortisol and ketosteroid excretion and improvement in electrolyte balance. Ketoconazole may be a useful adjunct in the treatment of small-cell lung cancer or other malignancies associated with excessive corticosteroid production or as a hormonal therapy in breast or prostatic cancer. Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Carcinoma, Small Cell; Cushing Syndrome; Humans; Hydrocortisone; Ketoconazole; Lung Neoplasms; Male; Middle Aged; Potassium | 1985 |
Oat-cell carcinoma of the lung simultaneously producing ACTH and serotonin.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Autopsy; Biological Assay; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Circadian Rhythm; Dexamethasone; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Lung Neoplasms; Male; Microscopy, Electron; Middle Aged; Radioimmunoassay; Serotonin | 1973 |