17-ketosteroids has been researched along with Breast-Neoplasms* in 178 studies
9 review(s) available for 17-ketosteroids and Breast-Neoplasms
Article | Year |
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Control of secretion and the function of C19-delta 5-steroids of the human adrenal gland.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Aging; Aldehyde-Lyases; Androgens; Androstenediol; Animals; Anorexia Nervosa; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estrogens; Fasting; Female; Glucocorticoids; Humans; Hypophysectomy; Japan; Menopause; Middle Aged; Obesity; Prolactin; Puberty; Steroid 17-alpha-Hydroxylase; Stress, Physiological; Sulfotransferases; Sulfurtransferases; Surgical Procedures, Operative; United States | 1985 |
[Intracellular and extracellular proteins binding androgenic hormones. Biochemical properties and clinical significance].
This paper has been designed to review some current concepts about biochemistry, pathophysiology and clinics of androgen-binding proteins, both TeBG and cellular receptors. Some important experimental models to clarify the interactions between androgens and target cells are mentioned. Further, major clinical applications in which binding parameters were or will be of great importance are discussed in details. Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Androgen-Binding Protein; Androgen-Insensitivity Syndrome; Breast Neoplasms; Carrier Proteins; Danazol; Disorders of Sex Development; Female; Humans; Hyperthyroidism; Infertility, Male; Liver Cirrhosis; Male; Minoxidil; Receptors, Androgen; Sex Hormone-Binding Globulin; Spironolactone | 1983 |
The role of hormones in the etiology of human breast cancer.
Topics: 17-Ketosteroids; Androgens; Androsterone; Breast Neoplasms; Contraceptives, Oral, Hormonal; Estradiol; Estriol; Estrogens; Estrone; Etiocholanolone; Female; Humans; Hypothyroidism; Menopause; Menstruation; Progesterone; Prolactin; Thyroid Hormones | 1977 |
Ablation therapy for hormone-dependent tumors.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenalectomy; Animals; Breast Neoplasms; Castration; Cortisone; Diabetes Insipidus; Endocrine Glands; Estrogens; Female; Growth Hormone; Humans; Hypophysectomy; Hypothyroidism; Mastectomy; Menopause; Menstruation; Ovary; Prolactin; Protein Binding; Receptors, Cell Surface; Sulfurtransferases; Time Factors | 1972 |
Biochemical procedures in different forms of cancer.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acid Phosphatase; Adrenal Gland Neoplasms; Alkaline Phosphatase; Amino Acids; Amylases; Bone Neoplasms; Breast Neoplasms; Carcinoid Tumor; Catecholamines; Chorionic Gonadotropin; Clinical Enzyme Tests; Clinical Laboratory Techniques; Female; Glucose-6-Phosphate Isomerase; Humans; Hydroxyindoleacetic Acid; L-Lactate Dehydrogenase; Liver Neoplasms; Male; Neoplasms; Neoplasms, Nerve Tissue; Neuroblastoma; Nucleotidases; Pancreatic Neoplasms; Pheochromocytoma; Pregnancy; Prostatic Neoplasms; Trophoblastic Neoplasms; Vanilmandelic Acid | 1971 |
[Steroids and breast cancer. Pharmacologic and therapeutic introduction].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenalectomy; Age Factors; Breast Neoplasms; Castration; Cortisone; Estrogens; Female; Gonadotropins; Humans; Hypophysectomy; Mastectomy; Menopause; Middle Aged; Neoplasm Metastasis; Pituitary Hormones, Anterior; Steroids | 1970 |
[Steroid changes in malignant mastopathy].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Animals; Breast Neoplasms; Estradiol; Estriol; Estrogens; Etiocholanolone; Female; Humans; Steroids | 1970 |
[Adrenalectomy as a therapeutic method of progressive mammary cancer].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenalectomy; Adult; Aged; Breast Neoplasms; Estrogens; Gonadotropins; Humans; Hypophysectomy; Methods; Middle Aged; Postoperative Care; Preoperative Care; Prolactin | 1969 |
SELECTIVE CRITERIA FOR SURGICAL REMOVAL OF THE ENDOCRINE GLANDS IN ADVANCED BREAST CANCER.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenalectomy; Androgens; Breast Neoplasms; Calcium; Castration; Drug Therapy; Endocrine Glands; Estrogens; Glucuronidase; Humans; Hypophysectomy; Mastectomy; Metabolism; Neoplasm Metastasis; Neoplasms; Urine | 1965 |
2 trial(s) available for 17-ketosteroids and Breast-Neoplasms
Article | Year |
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Adrenal function in patients treated with testosterone and fluorinated pyrimidines.
Topics: 17-Ketosteroids; Adenocarcinoma; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Aged; Breast Neoplasms; Clinical Trials as Topic; Female; Floxuridine; Fluorouracil; Humans; Male; Middle Aged; Pituitary-Adrenal Function Tests; Rectal Neoplasms; Sertoli-Leydig Cell Tumor; Stomach Neoplasms; Testosterone | 1968 |
Hormonal therapy in cancer of the breast. XXIV. Effect of corticosterone or medroxyprogesterone acetate on clinical course and hormonal excretion.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Breast Neoplasms; Calcium; Clinical Trials as Topic; Corticosterone; Creatinine; Female; Gonadotropins; Humans; Luteinizing Hormone; Medroxyprogesterone; Neoplasm Metastasis; Potassium Chloride; Pregnanediol; Tetrazolium Salts | 1967 |
167 other study(ies) available for 17-ketosteroids and Breast-Neoplasms
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New steroidal aromatase inhibitors: suppression of estrogen-dependent breast cancer cell proliferation and induction of cell death.
Aromatase, the cytochrome P-450 enzyme (CYP19) responsible for estrogen biosynthesis, is an important target for the treatment of estrogen-dependent breast cancer. In fact, the use of synthetic aromatase inhibitors (AI), which induce suppression of estrogen synthesis, has shown to be an effective alternative to the classical tamoxifen for the treatment of postmenopausal patients with ER-positive breast cancer. New AIs obtained, in our laboratory, by modification of the A and D-rings of the natural substrate of aromatase, compounds 3a and 4a, showed previously to efficiently suppress aromatase activity in placental microsomes. In the present study we have investigated the effects of these compounds on cell proliferation, cell cycle progression and induction of cell death using the estrogen-dependent human breast cancer cell line stably transfected with the aromatase gene, MCF-7 aro cells.. The new steroids inhibit hormone-dependent proliferation of MCF-7aro cells in a time and dose-dependent manner, causing cell cycle arrest in G0/G1 phase and inducing cell death with features of apoptosis and autophagic cell death.. Our in vitro studies showed that the two steroidal AIs, 3a and 4a, are potent inhibitors of breast cancer cell proliferation. Moreover, it was also shown that the antiproliferative effects of these two steroids on MCF-7aro cells are mediated by disrupting cell cycle progression, through cell cycle arrest in G0/G1 phase and induction of cell death, being the dominant mechanism autophagic cell death. Our results are important for the elucidation of the cellular effects of steroidal AIs on breast cancer. Topics: 17-Ketosteroids; Androstanes; Animals; Aromatase; Aromatase Inhibitors; Autophagy; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Shape; DNA; Dose-Response Relationship, Drug; Estrogens; Female; Humans; Molecular Structure; Neoplasms, Hormone-Dependent; Postmenopause; Receptors, Estrogen; Steroids; Vacuoles | 2008 |
[Hormonal profiles and structures in normal women and in patients with benign and malignant breast diseases].
Topics: 17-Ketosteroids; Adult; Breast Diseases; Breast Neoplasms; Estradiol; Female; Humans; Hydrocortisone; Middle Aged; Progesterone; Prolactin; Thyrotropin; Thyroxine | 1984 |
[Evaluation of the immunological reactivity and hormonal profile in patients with breast cancer].
Excretion of 17-HOCS and estrogens as well as the levels of E-RFC and time-delayed DNCB and tuberculin (PPD) contact sensitization reaction were studied in 136 breast cancer patients. A decrease in immunological response in reproductive and menopausal patients was matched by the development of relative hyperestrogenism and elevation of 17-HOCS excretion in the former group and a rise in 17-HOCS excretion only in the latter. Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aged; Breast Neoplasms; Estrogens; Female; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Middle Aged; Prognosis; Rosette Formation; Tuberculin Test | 1984 |
Some aspects of the endocrine status in the inflammatory breast carcinoma (Mastitis carcinosa).
The main endocrine features in a group of 87 patients with inflammatory breast carcinoma with very rapid evolution (group I) and those of 400 patients with breast cancer with no inflammatory signs (group II) have been compared. The mean age at menarche showed a significantly higher degree in group I, where the later menarche was reported in 36.8% of cases (greater than or less than 16 years). The mean number of abortions has been decreased in the same groups. No significant differences regarding to parity, lactation and mean age of the menopause have been found in these two groups. The mean values for total urinary estrogens were significantly higher in group I. The main fractions of 17-ketosteroids were estimated in 60 women of group I and 61 women of group II. The mean levels of these hormones were more decreased in group I, the most significantly differences in these two groups were registered for ethiocholanolone. In the most cases with decreased levels of ethiocholanolone, the survival time was also shorter. Such data showed a more prominent endocrine imbalance in the inflammatory breast carcinoma in comparison with breast cancer patients of normal evolution. Topics: 17-Ketosteroids; Adult; Age Factors; Aged; Breast Neoplasms; Estrogens; Etiocholanolone; Female; Humans; Mastitis; Menarche; Menopause; Middle Aged; Pregnancy | 1982 |
Predicting treatment response in breast cancer using urinary discriminant ratio and receptor assay.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adult; Aged; Breast Neoplasms; Female; Humans; Middle Aged; Receptors, Estrogen; Receptors, Progesterone | 1981 |
[Steroid balance in breast cancers of varying histological structure].
Patients with breast cancer in stage I--II of various histological structure showed varied hormonal disturbances. In adenocarcinoma a high level of classic estrogens or total phenolsteroids was noted. In low differentiated cancers (solid, scirrhus) the values of estrogens excretion were considerably lower, but, if correlated with other hormones (androsterone), a relative hyperestrogenization is observed. Scirrhous cancers are characterized by the increased 17-ketogenic steroids excretion. The character of hormonal disturbances concomitant with the predominant development of certain breast tumor structures (adenocarcinoma, solid cancer, scirrhus) is identical for the patients being in their reproductive and menopausal period. Topics: 17-Ketosteroids; Adenocarcinoma; Adenocarcinoma, Scirrhous; Adult; Breast Neoplasms; Carcinoma; Estrogens; Female; Gonadotropins; Humans; Menopause; Menstruation; Middle Aged; Steroids; Sterols | 1980 |
Identification of breast cancer patients with high risk of early recurrence after radical mastectomy: III. Steroid hormones measured in urine.
The relationship of the levels of selected urinary steroid metabolites to breast cancer recurrence after radical mastectomy was studied. An analysis of variance of the steroid measurements suggested that the measurements standardized to per gram of creatinine were the appropriate measure to use in exploring these relationships. No significant associations were found for premenopausal patients; however, for postmenopausal patients, low levels of total 17-ketosteroids were associated with a reduced two-year recurrence-free rate whereas low and high levels of OHA and high levels of total estrogens were associated a relatively low high two-year recurrence-free rate. Because of the large number of significance tests performed and the lack of consistent patterns, it is questionable whether the observed associations are of any importance. Including these steroid quantities in a multivariate regression model along with previously determined clinical prognostic factors indicated that the steroid determinations were the least important variables and did not make a significant contribution to the fit of the model. Topics: 17-Ketosteroids; Analysis of Variance; Androsterone; Breast Neoplasms; Estrogens; Female; Hormones; Humans; Mastectomy; Menopause; Middle Aged; Neoplasm Recurrence, Local; Risk | 1980 |
Urinary free cortisol, cortisone, cortisol sulfate, cortisone sulfate and 17-ketosteroids in breast cancer.
Topics: 17-Ketosteroids; Adult; Androsterone; Breast Neoplasms; Cortisone; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Hydrocortisone; Middle Aged; Time Factors | 1979 |
Ratio of 11-desoxy 17-oxosteroids to creatinine in a population screened for breast cancer.
During a population-based screening project for breast cancer, almost 15,000 women aged 50 years and over have provided a 12 h (overnight) sample of urine for research purposes. In 3,789 women the excretion of 11-desoxy-17-oxosteroids (DOOS) and creatinine was measured. Results were analysed in terms of urinary concentrations and of a ratio between DOOS and creatinine. Age had an effect on DOOS, creatinine and their ratio. Body weight and body surface area had an effect on creatinine excretion and therefore on the ratio. The following variables did not have an appreciable effect on the above-mentioned ratio: a family history of breast cancer, parity and age at first pregnancy, menopause and oestrogenic drugs, and parenchymal pattern of the breast as observed on the xeromammogram. Breast cancer was found at first screening in 106 out of 14,697 women. In 100 of these cases DOOS and creatinine were measured. Excretion values expressed as the ratio between the two, allowing for body surface area, did not differ materially from those of 100 age-matched controls. These results lead the authors to the conclusion that the determination of androgen metabolite excretion in women over 50 years of age is of no help in selecting a group at high risk of breast cancer. Topics: 17-Ketosteroids; Adult; Age Factors; Body Height; Body Weight; Breast; Breast Neoplasms; Creatinine; Female; Humans; Maternal Age; Menopause; Middle Aged; Parity; Pregnancy | 1979 |
[State of immunological reactivity in breast cancer patients receiving prednisolone treatment].
Topics: 17-Ketosteroids; Adult; Breast Neoplasms; Female; Humans; Hydroxysteroids; Hypersensitivity, Delayed; Immunity, Cellular; Leukocyte Count; Lymphocyte Activation; Middle Aged; Prednisolone; Skin Tests; Time Factors | 1979 |
Levels of principal 17-ketosteroid fractions in urine of breast cancer patients with or without malignant evolutive push.
The main fractions of 17-ketosteroids were estimated in 102 women with breast cancer. Sixty two patients were cases with rapid evolution (malignant evolutive push) or very rapid evolution (inflammatory breast carcinoma). The mean ethiocholanolone levels and partially androsterone levels were significantly decreased in patients with rapid evolution in comparison with the corresponding values found in patients with breast cancer of slow growth. Topics: 17-Ketosteroids; Adult; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Middle Aged; Neoplasm Invasiveness | 1978 |
[Glucuronic acid, glucuronyltransferase and estrogens in breast cancer and precancer].
The glucuronic acid level in the serum and urine, the diural excretion of estrogens and 17-KS with the urine, the activity of glucuronyltransferase are reported in 101 patients with benign and malignant tumors and in 22 healthy females. The decrease in the activity of glucurolytransferase and increase in the percentage of free (nonconjugated) estrogens in patients with malignant tumors of the mammary gland are noted, the analogous results were obtained in patients with benign tumors, but these are statistically insignificant. The decrease of the glucuronyltransferase activity is suggested to result in the development of relative hyperestrogen in normal total excretion. Topics: 17-Ketosteroids; Adult; Breast Neoplasms; Enzyme Activation; Estrogens; Estrogens, Conjugated (USP); Female; Free Radicals; Glucuronates; Glucuronosyltransferase; Humans; Middle Aged; Precancerous Conditions | 1978 |
Prediction of response to adrenalectomy in the treatment of advanced breast cancer.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenalectomy; Aged; Androsterone; Breast Neoplasms; Etiocholanolone; Female; Humans; Middle Aged; Neoplasm Metastasis; Prognosis; Remission, Spontaneous; Statistics as Topic | 1978 |
Urinary steroid hormones in normal Japanese women and primary breast cancer patients.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aged; Androgens; Breast Neoplasms; Estrogens; Female; Humans; Japan; Menopause; Middle Aged | 1978 |
Plasma androstenedione levels in women with breast cancer.
Topics: 17-Ketosteroids; Aged; Androstenedione; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; Mastectomy; Menopause; Middle Aged; Neoplasm Metastasis | 1977 |
Steroid hormones and human breast cancer. An hypothesis.
The likely occurrence of two distinct types of human breast cancer is discussed. In the development of the "Western-environmental" or "adrenal" type, it is proposed that dehydroepiandrosterone sulphate (DHEAS), secreted by the adrenal, may be implicated. This steroid is metabolized by mammary tumors to active androgens and estrogens. That these metabolic pathways are very similar to that in skin is emphasized and this is possibly explained by evolution of the mammary gland from primitive sweat glands. Formation of DHEAS from DHEA in mammary tumors, claimed to be correlated with an individual subject's prognosis and response to hormone ablation, is discussed in the light of a possible regulatory role of the sulphotransferase. It is proposed furthermore that a specific control of DHEAS secretion in the adrenal may exist at the level of the sulphurylation step. Nutritional factors are also possibly implicated here and these are discussed in the light of: 1) a possible higher secretion rate of DHEAS in obese subjects; and 2) the low breast cancer incidence in the Japanese and the accompanying low blood DHEAS levels. Topics: 17-Ketosteroids; Adrenal Glands; Breast Neoplasms; Cholesterol; Dehydroepiandrosterone; Estradiol; Female; Humans; Japan; Obesity; Skin; Sulfurtransferases; United States | 1977 |
Urinary steroid profiles in normal women and in patients with breast cancer in Britain and Japan: relation to thyroid function.
Topics: 17-Ketosteroids; Breast Neoplasms; Female; Humans; Japan; Menopause; Pregnanediol; Pregnanetriol; Thyrotropin; United Kingdom | 1977 |
Correlation between urinary steroids and estrogen receptor content in women with early breast cancer.
Topics: 17-Ketosteroids; Adult; Aged; Breast Neoplasms; Female; Humans; Menopause; Middle Aged; Receptors, Estrogen; Time Factors | 1977 |
Observations on urinary 17-ketosteroids in breast cancer patients.
Topics: 17-Ketosteroids; Adult; Aged; Breast Neoplasms; Female; Humans; Middle Aged; Neoplasm Staging | 1977 |
Relationship between steroid excretion patterns and breast cancer incidence in Israeli women of various origins.
A nationwide study of the steroid excretion patterns in postmenopausal Israeli migrant women demonstrated differences between high- and low-risk groups for breast cancer in the following variables: age at first parturition, number of pregnancies, number of live births, height, and weight. The direction of the differnces was in line with those observed for breast cancer patients. The groups also differed in the exretion of estriol, 17-ketosteroids, and allotetrahydrocortisol. Multiple regression analysis revealed that the exretion of estriol was significantly lower in population groups in whom breast cancer incidence was high. Possibly this trend--which has also been observed in adolescent and premenopausal women--reflected environmental influences on peripheral estrogen metabolism. Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Aged; Androgens; Breast Neoplasms; Environment; Estriol; Estrogens; Estrone; Female; Humans; Israel; Menopause; Middle Aged; Risk; Sampling Studies | 1977 |
[Correlation between the X-sex chromatin characteristics of breast cancer and the hormonal profile of women with breast cancer].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aged; Breast Neoplasms; Circadian Rhythm; Estrogens; Female; Hormones; Humans; Middle Aged; Sex Chromatin; Sex Chromosomes | 1977 |
Plasma dehydroepiandrosterone concentration in normal women and in patients with benign and malignant breast disease.
Topics: 17-Ketosteroids; Adult; Aged; Breast; Breast Diseases; Breast Neoplasms; Chromatography, Gas; Dehydroepiandrosterone; Female; Humans; Mastectomy; Middle Aged; Sulfates | 1976 |
Mammary carcinoma in an acromegalic patient.
Topics: 17-Ketosteroids; Acromegaly; Adenocarcinoma, Scirrhous; Breast Neoplasms; Female; Gonadotropins; Humans; Middle Aged | 1976 |
The urinary excretion of pregnanetriol and pregnenetriol in patients with breast cancer. A postulation on the meaning of Bulbrook's discriminant.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Biometry; Breast Neoplasms; Female; Humans; Pregnanetriol; Pregnenes; Stimulation, Chemical | 1976 |
Estrogen receptor in breast cancer of the Japanese.
The estrogen receptor was assayed, using the 2,000g supernatant and dextran-coated charcoal method, in 243 tissue samples from human breast cancer, benign breast diseases, macroscopically normal breast tissues, normal uterine myometrium, and uterine myoma. The estrogen receptor was found to be positive in 52.1% of 98 primary breast cancer and in 54.1% of 24 metastatic tumors. The receptor in the breast cancer was found to be similar to that in normal uterine myometrium in the binding character; that is, the dissociation constant of 10(-9) approximately 10(-11) M and number of binding sites of 0 approximately 2,800 fmol/mg protein. There was no correlation between the presence of the receptor and some clinical factors such as menopausal status, age of the patient, urinary 17-ketosteroid excretion, clinical stage of cancer, tumor size, positive or negative axillary lymph node metastasis, histological type, metastatic site of the cancer, or disease-free interval. The estrogen receptor appeared to be retained by metastasis of cancer, and this may lead to the use of the receptor assay with mastectomy specimens for the prediction of response to hormonal therapy in future recurrence of malignancy. Furthermore, it may be possible by this assay to select patients suitable for adjuvant therapy with hormones at the time of mastectomy. A good correlation was found between the presence of the receptor and response to the major endocrine ablation therapy in patients with advanced or metastatic breast cancer. When the receptor was negative in the cancer tissue, the change of response to the endocrine therapy was minimum. On the other hand, if the cancer contained the receptor, approximately 60% of the patients with metastatic or advanced breast cancer responded well to the major endocrine ablation therapy. Thus, the estrogen receptor of breast cancer in Japanese patients appears to bear a close resemblance to that reported in Western patients in its incidence and the correlation to some biological characteristics of the cancer. Topics: 17-Ketosteroids; Adenocarcinoma, Scirrhous; Adrenalectomy; Breast; Breast Neoplasms; Carcinoma; Castration; Female; Humans; Leiomyoma; Menopause; Menstruation; Myometrium; Neoplasm Metastasis; Receptors, Estrogen; Uterine Neoplasms | 1976 |
Follow-up study of left suprarenal to inferior mesenteric venous shunt for advanced breast cancer.
Major endocrine ablation therapy was carried out in 133 patients with advanced breast cancer. Of 40 patients undergoing left suprarenal to inferior mesenteric venous shunt with bilateral oophorectomy and right adrenalectomy, 16 cases (40 per cent) had an objective response. The mean postoperative survival of the patients with a positive response, those showing some response and those who failed to respond was 35-8, 26-5 and 8-8 months respectively. Thus, the results of the present procedure are comparable to those of adrenalectomy. No replacement therapy with corticoids was necessary. An increase in the response rate and extension of the survival time can be expected with the addition of postoperative long term maintenance therapy with chemotherapeutic agents and androgens. Topics: 17-Ketosteroids; Adrenal Glands; Adrenalectomy; Adult; Breast Neoplasms; Castration; Female; Follow-Up Studies; Humans; Liver Neoplasms; Mesenteric Veins; Middle Aged; Mitomycins; Neoplasm Metastasis; Time Factors | 1976 |
[Change in the excretion of adrenal steroids as dependent on the chlodithane (2,4'-DDD) concentration in the blood of oncological patients].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenocarcinoma; Adrenal Cortex Hormones; Adrenal Glands; Breast Neoplasms; Circadian Rhythm; Female; Humans; Kidney Neoplasms; Male; Mitotane; Neoplasms; Prostatic Neoplasms | 1976 |
Investigation of 17-ketosteriod excretion in mastopathia and premenopausal breast cancer.
Measurement of the excretion of total 17-ketosteroids, androsterone, etiocholanolone, and dehydroepiandrosterone demonstrate in contrast to the well known age dependency of normal women in cases of both mastopathia and breast cancer the following results: 1. the age dependence of the 17-ketosteriod excretion is not marked; 2. the total 17-ketosteroid excretion is lower than that of normal controls, 3. the values of the etiocholanolone excretions and that of the dehydroepiandrosterone excretions are similarly lower. Topics: 17-Ketosteroids; Adult; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Menopause; Middle Aged; Precancerous Conditions | 1975 |
Urinary excretion of 17-ketosteroids in patients suffering from mammary cancer.
1. The excretion of dehydroepiandrosterone is lower in patients suffering from mammary cancer than in healthy women. 2. There doesn't exist any relation between the 17-ketosteroid excretion and the age of postmenopausal women. 3. Patients with mammary tumors in stages III and IV are characterized by a lower excretion of dehydroepiandrosterone in percental parts than patients in stages I and II. 4. In patients with mammary tumors in stages III and IV and in patients with recurrences independently from the tumor stages we find higher extrem values for aetiocholanolone and smaller ones for dehydroepiandrosterone than in the other stages. 5. The quotient of percental parts of excreted aetiocholanolone to dehydroepiandrosterone shows significantly higher values for patients with recurrences than without them. 6. The quotient of aetiocholanolone to dehydroepiandrosterone is not a valid factor for a postoperative control of recurrences of the disease. Topics: 17-Ketosteroids; Aged; Breast Neoplasms; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Menopause; Middle Aged; Neoplasm Metastasis | 1975 |
The excretion of 17-ketosteroids in patients suffering from mastopathia fibrocystica and mammary carcinomas.
Comparative investigations of the urinary excretion of different 17-ketosteroids in healthy women and patients suffering from mastopathia fibrocystica and/or mammary carcinomas had the following results: 1. A clear age dependency of the excretion of 17 ketosteroids during the regenerative period has been shown in all groups investigated, but it could not be observed during the postmenopausal phase. 2. There are no hints by the excretion values for a remarkable contribution of mammary carcinomas to the hormone metabolism of the host. 3. The excretion values of patients suffering from mastopathia fibrocystica confirm epidemiological results, which consider this from of mastopathia a precancerous one. Topics: 17-Ketosteroids; Adult; Age Factors; Aged; Androsterone; Breast Diseases; Breast Neoplasms; Cysts; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Middle Aged; Precancerous Conditions | 1975 |
Androgens in postmenopausal breast cancer: excretion, production and interaction with estrogens.
Topics: 17-Ketosteroids; Aged; Androgens; Androstenedione; Binding, Competitive; Breast Neoplasms; Dehydroepiandrosterone; Dihydrotestosterone; Estradiol; Estrone; Female; Humans; Menopause; Middle Aged; Myometrium; Receptors, Cell Surface; Testosterone | 1975 |
Editorial: Breast cancer and the discriminant.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenalectomy; Adult; Breast Neoplasms; Estriol; Female; Humans; Hypophysectomy | 1975 |
Hormonal status of breast cancer. II. Abnormal urinary steroid excretion.
The urinary excretion of 14 neutral steroids was measured by gas-liquid chromatography in women with early and advanced breast cancer, in women with early uterine cancer, and in healthy women from urban and rural districts. The premenopausal patients with early breast cancer excreted subnormal amounts of five steroids (11-hydroxyandrosterone, 11-hydroxyetiocholanolone, pregnanediol, pregnanetriol, and tetrahydrocorticosterone) and increased amounts of tetrahydrocortisol as compared with the normal subjects of corresponding ages. From our findings, a new parameter was proposed by which a premenopausal breast-cancer patient was separated from the control. Postmenopausal breast-cancer patients excreted greater amounts of five steroids (one steroid from 17-ketosteroids and four from 17-hydroxycorticoids) than the corresponding controls. The discrepancy between premenopausal and postmenopausal breast cancer was tentatively related to ovarian-adrenal dysfunction in the course of aging. Oophorectomy induced a long-lasting tumor regression only in patients with a high value for the ratio of 11-deoxy-17-ketosteroid to 17-hydroxycorticosteroid in urine taken before surgery; the ratio in the responsive patients decreased remarkably after surgery. A constitutional change in 17-ketosteroids, as observed in a postmenopausal breast-cancer patient and a premenopausal healthy woman of urban origin, favored the geographic importance in the genesis of breast malignancy. The steroid abnormalities in uterine cancer were distinguishable from those of breast cancer in both premenopausal and postmenopausal women. Topics: 11-Hydroxycorticosteroids; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Aging; Androgens; Androsterone; Breast Neoplasms; Corticosterone; Etiocholanolone; Female; Humans; Menopause; Ovary; Pregnanediol; Pregnanetriol; Progestins; Rural Population; Tetrahydrocortisol; Urban Population; Uterine Neoplasms | 1975 |
Urinary excretion of steroids by Japanese women with breast cancer.
The urinary excretion of steroids was determined in premenopausal patients with advanced breast cancer in the non-menstrual phase and in control women in the follicular phase, ovulatory stage, and luteal phase. The estrone level in the urine of cancer patients was higher than that in the urine of control women at any phase. Excretion of 17 beta-estradiol in the follicular and luteal phases was similar in the urine of control women and cancer patients, but estradiol and estriol levels in the ovulatory stage of control women were higher than those of cancer patients. The estriol level in the urine of control women in the luteal phase was also higher than that of cancer patients. Total 17-ketosteroid was lower in the urine of cancer patients than in that of controls at any phase. Among the fractions of 17-ketosteroids, only dehydroepiandrosterone was excreted at a higher level by cancer patients than by control subjects. Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Asian People; Breast Neoplasms; Estradiol; Estriol; Estrogens; Estrone; Female; Humans; Japan; Menstruation; Middle Aged; Ovulation | 1975 |
Urinary excretion of steroids and response to oophorectomy in premenopausal women with advanced breast cancer.
Relationship between the urinary excretion of steroids in premenopausal Japaneses patients with advanced breast cancer and their response to oophorectomy was studied. The estrogen fractions were determined by radioimmunoassay and those who responded to oophorectomy showed higher levels of 17 beta-estradiol than the non-responders before surgery. The high levels of urinary 17 beta-estradiol of the responders dropped markedly after oophorectomy. On the contrary, the non-responders showed relatively low levels of urinary excretion of 17 beta-estradiol before oophorectomy and the levels appeared either unchanged or slightly elevated after surgery. No definite relation was found between changes in the urinary excretion of estrone or estriol and the clinical effect of oophorectomy. Excretion of 17-ketosteroids in the responders was lower than that of the non-responders. Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Adult; Breast Neoplasms; Castration; Estradiol; Estriol; Estrogens; Estrone; Female; Humans; Menopause; Middle Aged; Neoplasm Metastasis | 1975 |
Clinical and hormonal aspects in breast cancer with special reference to malignant evolutive push.
It is tried to differentiate between various stages of malignant evolutive push and normal mammary tumors to establish an individual therapeutic procedure. Besides mammography and thermometry, investigations of urinary excretions of estrogenic and androgenic steriods are qualified for this purpose. Patients with malignant evolutive push showed an increased excretion of estrogens which reached its highest levels in patients suffering from inflammatory mammary carcinomas. The excretion of 17-ketosteroids shows a behaviour vice versa. Altogether mammary tumors with malignant evolutive push are characterized by a state of absolute and relative hyperestrogenity respectively. This phenomenon preferably depends on the clinical stage of the disease than on the age of the patients. Topics: 17-Ketosteroids; Adult; Aged; Breast Neoplasms; Female; Humans; Mammography; Middle Aged; Skin Temperature | 1975 |
[Endolumbar administration of hydrocortisone in the complex treatment of patients with generalized breast cancer].
An efficacy of the method of hormonal therapy--endolumbar hydrocortisone injection in patients with advanced breast cancer has been studied. A remission was gained in 28 of 41 patients. The method proved to be mostly effective in metastases in bones. Changes in the level of estrogens, 17-KS and 17-OCS excretion with the urine during the treatment indicate an endocrinous mechanism of this therapeutic effect. An efficacy of the method in extensive dissemination of the process, its relative simplicity and availability along with the absence of serious complications enabled the authors to hope that the suggested method may be widely used in practice. Topics: 17-Ketosteroids; Adult; Aged; Bone Neoplasms; Breast Neoplasms; Estrogens; Female; Humans; Hydrocortisone; Injections, Spinal; Middle Aged; Neoplasm Metastasis | 1975 |
Tryptophan metabolism and recurrence rates of patients with breast cancer after mastectomy.
Women with early breast cancer were given a loading dose of L-tryptophan after mastectomy and a comparison made between their excretion of metabolites of the kynurenine pathway and the rate of recurrence of the disease. Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Age Factors; Aged; Breast Neoplasms; Female; Humans; Kynurenine; Mastectomy; Menopause; Middle Aged; Time Factors; Tryptophan | 1975 |
Studies on the sulphate esters of dehydroepiandrosterone and androsterone in the blood of women with breast cancer.
Topics: 17-Ketosteroids; Adult; Aged; Androsterone; Breast Neoplasms; Chromatography, Gas; Dehydroepiandrosterone; Esters; Female; Humans; Mastectomy; Middle Aged; Sulfates; Time Factors | 1974 |
The breast cancer discriminant: effect of age, obesity, hirsutism, starvation, and changes in adrenocortical and gonadal activity.
Topics: 17-Ketosteroids; Adolescent; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Amenorrhea; Androsterone; Body Weight; Breast Neoplasms; Castration; Contraceptives, Oral; Dexamethasone; Estrogens; Etiocholanolone; Female; Hirsutism; Humans; Hypophysectomy; Luteinizing Hormone; Menstruation; Middle Aged; Obesity; Ovarian Diseases; Starvation | 1974 |
Identification of breast cancer patients with high risk of early recurrence after radical mastectomy. I. Description of study.
Topics: 17-Ketosteroids; Age Factors; Aged; Blood Vessels; Breast Neoplasms; Creatinine; Estrogens; Female; Follow-Up Studies; Glucocorticoids; Hematocrit; Humans; Lymph Nodes; Lymphatic Metastasis; Mastectomy; Neoplasm Recurrence, Local; Prognosis | 1974 |
[Hormonal patterns in breast cancers].
Urinary outpout of oestrogens and 17-ketosteroids were estimated in 200 women with breast cancer; 60 of them were cases with rapid evolution (malignant evolutive push). The majority of cases analysed had abnormal hormonal levels, especially of oestrogens. The average oestrogenic levels are higher than the normal values; the highest values correspond to the most severe and rapidly evolutive type of breast cancer, the inflammatory breast carcinoma. In the patients without evolutive push, the proportion of cases with absolute or relative hypooestrogeny is approximately equal toor exceeds the proportion of hyperoestrogenic cases. In the presence of the evolutive push and especially of his most severe type, inflammatory carcinoma, the cases with hyperoestrogeny, both absolute and relative, by hypoandrogeny, are dominant. The proportion of cases with higher 17-ketosteroid urinary outputs than the normal mean is greater in the patients without evolutive push, while in those with evolutive push, the majority of cases have lower values of 17-ketosteroids than the normal mean. Topics: 17-Ketosteroids; Adult; Aged; Breast Neoplasms; Edema; Estrogens; Female; Humans; Menopause; Middle Aged; Neoplasm Metastasis; Prognosis; Time Factors | 1974 |
Urinary and plasma androgens in benign breast disease. Possible relation to breast cancer.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Age Factors; Aged; Androgens; Breast Diseases; Breast Neoplasms; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Middle Aged; Sulfates | 1973 |
Basic results of a study of bilateral adrenalectomy for advanced breast cancer. Urinary steroids and related data in 148 patients.
Topics: 17-Ketosteroids; Adrenalectomy; Adult; Androsterone; Body Surface Area; Breast; Breast Neoplasms; Chromatography, Gas; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Menopause; Middle Aged; Palliative Care; Pregnancy; Remission, Spontaneous; Spectrophotometry; Time Factors | 1973 |
Androgen production and conversion to estrogens in normal postmenopausal women and in selected breast cancer patients.
Topics: 17-Ketosteroids; Aged; Androgens; Androstenedione; Androsterone; Breast Neoplasms; Carbon Isotopes; Climacteric; Dehydroepiandrosterone; Estradiol; Estriol; Estrone; Etiocholanolone; Female; Glucuronates; Humans; Metabolic Clearance Rate; Middle Aged; Sulfates; Testosterone; Tritium | 1973 |
[The mechanism of action of hydrocortisone administered by lumbar puncture in breast cancer].
Topics: 11-Hydroxycorticosteroids; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aged; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estriol; Estrogens; Estrone; Etiocholanolone; Female; Humans; Hydrocortisone; Injections, Spinal; Middle Aged; Neoplasm Metastasis | 1973 |
Preliminary trial of aminoglutethimide in breast cancer.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Administration, Oral; Aminoglutethimide; Antineoplastic Agents; Bone Neoplasms; Breast Neoplasms; Castration; Central Nervous System; Dexamethasone; Estrogens; Female; Fludrocortisone; Humans; Neoplasm Metastasis; Ovary; Remission, Spontaneous; Skin Neoplasms | 1973 |
Male breast cancer. 3. Breast carcinoma in association with the Klinefelter syndrome.
Topics: 17-Ketosteroids; Aged; Biopsy; Breast Neoplasms; Estrogens; Gonadotropins; Humans; Karyotyping; Klinefelter Syndrome; Male; Sex Chromatin; Sex Chromosomes; Testis | 1973 |
Metabolic changes in breast carcinoma. I. Urinary excretions of ketosteroid and catecholamine.
Topics: 17-Ketosteroids; Adolescent; Adult; Breast Neoplasms; Female; Humans; Male; Middle Aged; Spectrum Analysis; Vanilmandelic Acid | 1973 |
[Study on the hormonal etiology of breast cancer and atypical endometrial hyperplasia in women of pre-menopausal age].
Topics: 17-Ketosteroids; Breast Neoplasms; Endometrial Hyperplasia; Estrogens; Female; Humans; Menopause; Middle Aged; Testosterone | 1973 |
17-Ketosteroid excretion, myasthenia gravis, and breast cancer.
Topics: 17-Ketosteroids; Breast Neoplasms; Female; Humans; Male; Myasthenia Gravis; Thymectomy | 1972 |
[FSH and steroid hormone excretion in breast cancer during chemotherapy].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Breast Neoplasms; Cyclophosphamide; Estrogens; Female; Fluorouracil; Follicle Stimulating Hormone; Glucocorticoids; Humans; Menopause; Methotrexate; Neoplasm Metastasis; Neoplasm Recurrence, Local; Pregnanediol; Thiotepa; Time Factors; Vinblastine | 1972 |
A rapid method for the analysis of enzyme hydrolysable 11-deoxy-17-oxosteroids in urine.
Topics: 17-Ketosteroids; Androsterone; Breast Neoplasms; Chromatography, Ion Exchange; Dehydroepiandrosterone; Etiocholanolone; Evaluation Studies as Topic; Female; Glucuronates; Glucuronidase; Humans; Hydrolysis; Mass Screening; Methods; Sulfuric Acids; Tritium | 1972 |
Adrenal and testicular contribution to plasma oestrogens.
Topics: 17-Ketosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Androstanes; Breast Neoplasms; Castration; Dehydroepiandrosterone; Dexamethasone; Estradiol; Estrone; Female; Humans; Hydrocortisone; Hypertension; Iliac Vein; Male; Menopause; Middle Aged; Neoplasms; Radioligand Assay; Renal Veins; Testis; Testosterone | 1972 |
L-Dopa effect on prolactin, follicle-stimulating hormone, and luteinizing hormone in women with advanced breast cancer: a preliminary report.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Bone Neoplasms; Breast Neoplasms; Dihydroxyphenylalanine; Estradiol; Estriol; Estrone; Female; Follicle Stimulating Hormone; Growth Hormone; Humans; Luteinizing Hormone; Middle Aged; Neoplasm Metastasis; Progesterone; Prolactin | 1972 |
[Excretion of pituitary and steroid hormones in breast cancer following pituitary irradiation].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Breast Neoplasms; Estrogens; Female; Follicle Stimulating Hormone; Growth Hormone; Humans; Middle Aged; Pituitary Irradiation | 1972 |
The in vitro biosynthesis of 11 -hydroxyandrostenedione by human adrenal homogenates.
Topics: 17-Ketosteroids; Adrenal Glands; Androstanes; Breast Neoplasms; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Cushing Syndrome; Humans; Hydrocortisone; In Vitro Techniques; Progesterone; Tritium | 1972 |
[Reduced excretion of total gonadotropins during use of Elipten in breast neoplasms].
Topics: 17-Ketosteroids; Adult; Aminoglutethimide; Aniline Compounds; Anticonvulsants; Breast Neoplasms; Female; Gonadotropins; Humans; Middle Aged; Pyridones | 1972 |
Urinary androgen excretion and the etiology of breast cancer.
Topics: 17-Ketosteroids; Adult; Androgens; Androsterone; Breast Diseases; Breast Neoplasms; Endocrine Glands; Estrogens; Etiocholanolone; Female; Humans; Mastectomy; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies | 1972 |
Evaluation of breast tumour sex chromatin (Barr body) as an index of survival and response to pituitary ablation.
Topics: 17-Ketosteroids; Androsterone; Biopsy; Breast Neoplasms; Etiocholanolone; Female; Humans; Hypophysectomy; Retrospective Studies; Sex Chromatin | 1972 |
Hormonal influences in breast cancer.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenalectomy; Adult; Age Factors; Androsterone; Animals; Blood Glucose; Breast Neoplasms; Castration; Dehydroepiandrosterone; Estradiol; Estrogens; Etiocholanolone; Female; Growth Hormone; Hormones; Humans; Hypophysectomy; Insulin; Menopause; Mice; Pituitary Irradiation; Sulfates | 1971 |
[Influence of the presence at determinable levels of free plasma 17-ketosteroids on the survival of breast cancer patients].
Topics: 17-Ketosteroids; Adult; Aged; Breast Neoplasms; Female; Humans; Middle Aged; Prognosis; Testosterone | 1971 |
Relationships between excretion of steroid hormones and tryptophan metabolites in patients with breast cancer.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Administration, Oral; Adult; Age Factors; Breast Neoplasms; Chromatography, Thin Layer; Female; Fluorescence; Humans; Hydrolases; Kynurenine; Middle Aged; Neurospora; ortho-Aminobenzoates; Tryptophan; Xanthurenates | 1971 |
Probability of a woman with advanced breast cancer responding to adrenalectomy or hypophysectomy.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenalectomy; Adult; Age Factors; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Hypophysectomy; Menopause; Middle Aged; Probability | 1970 |
Steroid metabolism by human breast tumours.
Topics: 17-Ketosteroids; Androstanes; Breast Neoplasms; Chromatography, Thin Layer; Dehydroepiandrosterone; Estriol; Female; Humans; Testosterone; Tritium | 1970 |
Adrenal function in breast cancer: biogenesis of androgens and cortisol by the human adrenal gland in vivo.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adrenal Glands; Adrenalectomy; Adult; Aged; Androgens; Androstanes; Androsterone; Breast Neoplasms; Carbon Isotopes; Chromatography, Gas; Chromatography, Paper; Dehydroepiandrosterone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Middle Aged; Ovary; Pregnenolone; Progesterone; Radioisotope Dilution Technique; Tritium | 1970 |
Steroid metabolism by human breast tumours.
Topics: 17-Ketosteroids; Androstanes; Breast Neoplasms; Dehydroepiandrosterone; Dihydrotestosterone; Female; Humans; In Vitro Techniques; Mastectomy | 1970 |
Benign and malignant breast disease in South Wales: a study of urinary steroids.
The levels of aetiocholanolone, androsterone, and 17-hydroxycorticosteroids were measured in women without known disease of the breast, in women with benign breast disease, and in women with primary and advanced breast cancer. Statistical analysis showed there was no difference in the excretion of urinary 17-hydroxycorticosteroids in the various groups of patients. Detailed analysis of the aetiocholanolone and androsterone levels, however, indicated that patients with advanced localized disease excreted significantly less of these 11-deoxy-17-oxosteroids than those in the other groups. Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Androsterone; Breast Diseases; Breast Neoplasms; Chromatography, Gas; Chromatography, Paper; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Middle Aged; Wales | 1970 |
A single method for determination of urine steroids. I. Levels of testosterone, epitestosterone and 17-ketosteroid fractions. II. Specific activities of testosterone, androsterone and etiocholanolone and production rate of testosterone following administr
Topics: 17-Ketosteroids; Adolescent; Adult; Aged; Androsterone; Breast Neoplasms; Carbon Isotopes; Carcinoma; Child; Child, Preschool; Chromatography; Dehydroepiandrosterone; Endocrine System Diseases; Etiocholanolone; Female; Humans; Infant; Male; Methods; Middle Aged; Polycystic Ovary Syndrome; Prostatic Neoplasms; Testosterone; Tritium | 1970 |
[Irradiation of the ovaries in the complex therapy of breast cancer].
Topics: 17-Ketosteroids; Adenocarcinoma, Scirrhous; Adult; Breast Neoplasms; Castration; Estrogens; Female; Humans; Middle Aged; Ovary; Pregnanediol | 1970 |
[Prognostically important factors in mammary carcinoma].
Topics: 17-Ketosteroids; Adult; Age Factors; Aged; Breast Neoplasms; Estrogens; Female; Gonadal Steroid Hormones; Humans; Middle Aged; Prognosis | 1970 |
Urinary steroid excretion in patients with advanced breast cancer.
Topics: 17-Ketosteroids; Androsterone; Breast Neoplasms; Chromatography; Etiocholanolone; Female; Humans | 1970 |
[17-ketosteroid changes in breast cancer during testosterone propionate treatment].
Topics: 17-Ketosteroids; Breast Neoplasms; Chromatography; Female; Humans; Testosterone | 1970 |
Relationship between hormonal cytology and steroid excretion in post-menopausal women.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Aged; Androsterone; Breast Neoplasms; Estriol; Estrogens; Estrone; Etiocholanolone; Female; Humans; Menopause; Middle Aged; Urine; Uterine Neoplasms | 1970 |
[Endocrine characterization of mammary carcinoma].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aged; Androstanes; Breast Neoplasms; Female; Humans; Middle Aged | 1970 |
[Blood concentration and urinary excretion rate following intramuscular injection of triamcinolone acetonide].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adult; Breast Neoplasms; Chromatography, Thin Layer; Humans; Hydrocortisone; Injections, Intramuscular; Time Factors; Triamcinolone Acetonide; Tritium | 1970 |
Diagnosis and treatment of mastopathy.
Topics: 17-Ketosteroids; Adenofibroma; Adolescent; Adult; Aged; Animals; Breast Diseases; Breast Neoplasms; Columbidae; Crop, Avian; Estrenes; Estrogens; Female; Humans; Middle Aged; Pregnanediol; Prolactin | 1969 |
Further studies on the relationship between C19- and C21-steroid synthesis in the human adrenal gland.
Topics: 17-alpha-Hydroxypregnenolone; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Androgens; Breast Neoplasms; Carbon Isotopes; Dehydroepiandrosterone; Estrogens; Female; Humans; Hydrocortisone; In Vitro Techniques; Pregnenolone; Testosterone; Transferases; Tritium | 1969 |
Estradiol production after ovariectomy for carcinoma of the breast.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Breast Neoplasms; Castration; Estradiol; Female; Humans; Menopause; Middle Aged; Ovary; Tritium | 1969 |
[Therapeutic possibilities in metastatic cancer of the breast with hypercalcaemia. (Apropos of 2 cases)].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Bone Neoplasms; Breast Neoplasms; Castration; Cyclophosphamide; Estrogens; Female; Humans; Hypercalcemia; Middle Aged; Neoplasm Metastasis; Norethindrone; Ovary; Phosphoric Monoester Hydrolases; Phosphorus; Prednisone; Radiography; Testosterone | 1969 |
[Study of plasma 17-ketosteroids and 17-hydroxycorticosteroids in men having cancer of the breast].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aged; Breast Neoplasms; Humans; Klinefelter Syndrome; Male; Middle Aged | 1969 |
[Endocrine therapy and chemotherapy of breast cancer].
Topics: 17-Ketosteroids; Adrenalectomy; Adult; Age Factors; Aged; Androgens; Breast Neoplasms; Castration; Estrogens; Female; Humans; Hypophysectomy; Menstruation; Middle Aged; Mitomycins | 1969 |
[Peculiarities of hormonal metabolism in men with gynecomastia and breast cancer].
Topics: 17-Ketosteroids; Adult; Aged; Breast Neoplasms; Estrogens; Follicle Stimulating Hormone; Gynecomastia; Hormones; Humans; Male; Middle Aged | 1969 |
[Sex chromatin and hormonal status in patients with breast neoplasms].
Topics: 17-Ketosteroids; Adult; Breast Neoplasms; Estrogens; Female; Humans; Middle Aged; Sex Chromatin | 1969 |
[The relationship between the course of mammary gland cancer and age and hormonal features of the body].
Topics: 17-Ketosteroids; Adult; Age Factors; Breast Neoplasms; Estrogens; Female; Humans; Menstruation; Middle Aged; Pregnancy; Pregnancy Complications; Prognosis | 1969 |
Comparison of mastisol (2-alpha-methylandrostan-17-beta-ol-3-one propionate) and testosterone propionate in the treatment of advanced and recurrent cancer of the breast.
Topics: 17-Ketosteroids; Adult; Aged; Alkaline Phosphatase; Androstanols; Breast Neoplasms; Female; Humans; Middle Aged; Models, Structural; Propionates; Testosterone | 1969 |
[Examination of the luteotropic hormone activity of blood and urinary steroid excretion in diseases of the breast].
Topics: 17-Ketosteroids; Adenofibroma; Adolescent; Adult; Aged; Animals; Breast Diseases; Breast Neoplasms; Chromatography, Paper; Columbidae; Estradiol; Estriol; Estrogens; Estrone; Female; Humans; Luteinizing Hormone; Middle Aged; Pregnanediol | 1969 |
Urinary steroids and breast disease.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Breast Diseases; Breast Neoplasms; Female; Humans | 1969 |
Urinary steroid excretion pattern in diabetes mellitus.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Androgens; Androsterone; Breast Neoplasms; Diabetes Complications; Diabetes Mellitus; Etiocholanolone; Female; Glucocorticoids; Humans; Male; Pregnanes; Pregnanetriol; Progestins; Steroids | 1968 |
Effect of thyroid funtion and of obesity on discriminant function for mammary carcinoma.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aged; Androgens; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Etiocholanolone; Female; Glucocorticoids; Humans; Hyperthyroidism; Hypothyroidism; Middle Aged; Obesity; Prognosis; Thyroid Diseases | 1968 |
A correlation between urinary steroid metabolites and pathways of steroidogenesis in human breast-tumour tissue.
Topics: 17-Ketosteroids; Adenofibroma; Adrenalectomy; Adult; Aged; Androstanes; Breast Neoplasms; Carcinoma; Chemistry, Clinical; Dehydroepiandrosterone; Estriol; Female; Humans; Menopause; Middle Aged; Steroids | 1968 |
Urinary steroids in the prediction of response to adrenalectomy or hypophysectomy. A second clinical trial.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenalectomy; Breast Neoplasms; Female; Humans; Hypophysectomy; Neoplasm Metastasis; Ovary; Prognosis | 1968 |
Urinary 17-ketosteroid excretion of women with advanced breast cancer.
Topics: 17-Ketosteroids; Adrenalectomy; Adult; Aged; Androsterone; Asian People; Breast Neoplasms; Chemistry, Clinical; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Japan; Middle Aged | 1968 |
[Clinical study of urinary 17-ketosteroid fractions in breast cancer--correlation with the effect of adrenalectomy in progressive breast cancer].
Topics: 17-Ketosteroids; Adrenalectomy; Adult; Aged; Breast Neoplasms; Dehydroepiandrosterone; Female; Humans; Middle Aged | 1968 |
Ultrasonic selective hypophysectomy.
Topics: 17-Ketosteroids; Acromegaly; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Animals; Breast Neoplasms; Cushing Syndrome; Diabetic Retinopathy; Dogs; Female; Humans; Hydrocortisone; Male; Methods; Middle Aged; Pituitary Gland; Prostatic Neoplasms; Ultrasonic Therapy | 1968 |
Bilateral carcinoma of the breast in a patient with Klinefelter's syndrome.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenocarcinoma, Mucinous; Aged; Atrophy; Breast Neoplasms; Estrogens; Gynecomastia; Humans; Karyotyping; Klinefelter Syndrome; Male; Prostate | 1968 |
The metopirone test of pituitary corticotrophin release. Evaluation of 101 tests.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Breast Neoplasms; Child; Female; Glucocorticoids; Humans; Hyperpituitarism; Hypopituitarism; Male; Metyrapone; Middle Aged; Pituitary-Adrenal Function Tests; Tranquilizing Agents | 1968 |
Excretion of ketosteroids and proneness to breast cancer.
Topics: 17-Ketosteroids; Adult; Androsterone; Breast Neoplasms; Etiocholanolone; Female; Humans; Mastectomy | 1968 |
Urinary steroid spectra by gas chromatography.
Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adult; Breast Neoplasms; Child; Chromatography, Gas; Cushing Syndrome; Etiocholanolone; Female; Humans; Hypopituitarism; Male; Methods; Pheochromocytoma; Polycystic Ovary Syndrome; Pregnanes; Statistics as Topic; Steroids | 1968 |
[Urinary excretion of neutral 17-ketosteroids, androsterone and etiocholanolone in healthy women and women with early and advanced breast cancer].
Topics: 17-Ketosteroids; Aged; Androsterone; Breast Neoplasms; Chromatography; Etiocholanolone; Female; Glucocorticoids; Humans; Middle Aged; Paper; Time Factors | 1968 |
Urinary steroid excretion in patients with advanced breast cancer.
Topics: 17-Ketosteroids; Breast Neoplasms; Etiocholanolone; Female; Humans; Mathematics | 1968 |
[Study on the pyrogen test in normal subjects, hypopituitarism, hypothyroidism and adrenalectomized patients].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenalectomy; Breast Neoplasms; Humans; Hypopituitarism; Hypothyroidism; Pituitary-Adrenal Function Tests; Pyrogens | 1968 |
[Data on the treatment of gyneconastia].
Topics: 17-Ketosteroids; Adult; Aged; Breast Neoplasms; Gynecomastia; Humans; Male; Middle Aged; Precancerous Conditions; Sex Chromatin | 1968 |
[Lung metastasis of breast cancer in a male treated with pneumonectomy and orchiectomy following radical mastectomy].
Topics: 17-Ketosteroids; Breast Neoplasms; Castration; Humans; Lung Neoplasms; Male; Mastectomy; Middle Aged; Neoplasm Metastasis; Pneumonectomy | 1968 |
[The importance of studying steroid and hypophyseal hormone excretion in patients with dyshormonal tumors].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Breast Neoplasms; Castration; Choriocarcinoma; Estrogens; Female; Gonadal Steroid Hormones; Gonadotropins, Pituitary; Humans; Male; Ovarian Neoplasms; Pituitary Gland; Pregnancy; Thyroid Gland; Uterine Neoplasms | 1968 |
[Free and total plasma 17-ketosteroids in genital cancers. Study of women with breast or genital cancer and men with prostatic or testicular cancer].
Topics: 17-Ketosteroids; Breast Neoplasms; Castration; Female; Genital Neoplasms, Female; Humans; Male; Ovarian Neoplasms; Prostatic Neoplasms; Testicular Neoplasms; Uterine Cervical Neoplasms; Uterine Neoplasms; Vaginal Neoplasms | 1968 |
Alternative discriminating function for determining hormone dependency of breast cancer.
Topics: 17-Ketosteroids; Aging; Androsterone; Breast Neoplasms; Chromatography; Etiocholanolone; Female; Humans | 1967 |
Low-dosage glucocorticoid therapy. An appraisal of its safety and mode of action in clinical disorders, including rheumatoid arthritis.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adult; Aged; Alopecia Areata; Arthritis, Rheumatoid; Asthma; Breast Neoplasms; Child; Child, Preschool; Colitis, Ulcerative; Cortisone; Endocrine System Diseases; Female; Humans; Hydrocortisone; Male; Middle Aged; Multiple Sclerosis | 1967 |
Adrenal structure and function in advanced carcinoma of the breast. II. The relation of steroid excretion to adrenal morphology and the outcome of adrenalectomy, with description of a new discriminant function.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Breast Neoplasms; Carcinoma; Female; Humans; Middle Aged; Organ Size | 1967 |
Determination of 17-oxosteroid sulphates in human plasma.
Topics: 17-Ketosteroids; Adolescent; Adult; Aged; Breast Neoplasms; Chromatography, Thin Layer; Female; Fibrosarcoma; Humans; Male; Mass Screening; Methods; Middle Aged; Neoplasm Metastasis; Stomach Neoplasms; Ultraviolet Rays | 1967 |
[Comparative sudy of total 17-ketosteroids and free 17-hydroxycorticosteroids in the blood of women with breast cancer].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aged; Breast Neoplasms; Castration; Female; Humans; Mastectomy; Menopause; Middle Aged | 1967 |
[Clinical and morphological studies on gynecomastia].
Topics: 17-Ketosteroids; Adenocarcinoma; Adult; Age Factors; Aged; Breast Neoplasms; Carcinoma; Epithelium; Estrogens; Gynecomastia; Humans; Japan; Liver Function Tests; Male; Middle Aged; Mitosis; Prostatic Hyperplasia; Prostatic Neoplasms | 1967 |
The urinary excretion of 11-deoxy-17-oxosteroids and 17-hydroxycorticosteroids by normal Japanese and British women.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aged; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Ethnology; Etiocholanolone; Female; Humans; Japan; London; Middle Aged; Women | 1967 |
Urine steroid excretion in postmenopausal cancer of the breast. Response to corticotropin stimulation and dexamethasone suppression.
Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Aged; Breast Neoplasms; Dexamethasone; Estrogens; Female; Humans; Lymphatic Metastasis; Menopause; Middle Aged; Pregnanediol | 1967 |
Urinary steroid spectrum by gas chromatography.
Topics: 17-Ketosteroids; Addison Disease; Adrenocorticotropic Hormone; Androgens; Breast Neoplasms; Chemistry, Clinical; Cholesterol; Chromatography, Gas; Female; Humans; Male; Metyrapone; Ovarian Neoplasms; Pregnancy; Steroids | 1967 |
[Circadian rhythm and low frequency rhythms in human physiology].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Age Factors; Animals; Body Temperature; Breast Neoplasms; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Circadian Rhythm; Computers; Electroencephalography; Female; Humans; Infant; Information Systems; Light; Male; Metabolism; Mice; Middle Aged; Mitosis; Models, Theoretical; Periodicity; Sleep; Spectrum Analysis; Time Factors | 1967 |
[Ultrasonic hypophysectomy on breast and prostatic carcinomas and in Cushing's syndrome. Principles and indications of hypophysis surgery].
Topics: 17-Ketosteroids; Acromegaly; Animals; Bone Neoplasms; Breast Neoplasms; Cushing Syndrome; Diabetic Retinopathy; Dogs; Female; Humans; Hypophysectomy; Male; Methods; Neoplasm Metastasis; Pituitary Gland; Prostatic Neoplasms; Ultrasonic Therapy | 1967 |
The effect of steroidal diosphenol agents on advanced breast cancer.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenocarcinoma; Adult; Aged; Alkaline Phosphatase; Animals; Antineoplastic Agents; Aspartate Aminotransferases; Breast Neoplasms; Cyclohexanes; Estrogens; Female; Gonadotropins; Gonadotropins, Pituitary; Humans; Isocitrate Dehydrogenase; L-Lactate Dehydrogenase; Liver Function Tests; Male; Mammary Neoplasms, Experimental; Mice; Middle Aged; Prolactin; Rats; Sulfobromophthalein; Testosterone | 1967 |
[Clinical study on adrenal suppression and estrogens in recurrent breast cancer].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aged; Breast Neoplasms; Estrogens; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Paramethasone | 1966 |
[On the metabolism of phosphates and sulfates of androsterone and epiandrosterone].
Topics: 17-Ketosteroids; Androgens; Androstanes; Androsterone; Breast Diseases; Breast Neoplasms; Chromatography, Paper; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Phosphates; Sulfates | 1966 |
Urinary hormone metabolite levels in patients with cancer of the breast, prostate and lung.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Breast Neoplasms; Estrogens; Female; Gonadotropins; Hormones; Humans; Lung Neoplasms; Male; Pregnanediol; Prostatic Neoplasms | 1966 |
[Endocrine treatment of breast cancer].
Topics: 17-Ketosteroids; Adrenalectomy; Breast Neoplasms; Castration; Female; Gonadal Steroid Hormones; Humans; Neoplasm Metastasis | 1966 |
CARCINOMA OF MALE BREAST IN ASSOCIATION WITH THE KLINEFELTER SYNDROME.
Topics: 17-Ketosteroids; Adenocarcinoma; Adenocarcinoma, Scirrhous; Adrenal Cortex Hormones; Biopsy; Breast; Breast Neoplasms; Carcinoma, Ductal; Chromosomes; Fluids and Secretions; Gonadotropins; Gynecomastia; Humans; Klinefelter Syndrome; Male; Neoplasm Metastasis; Neoplasms; Pathology; Urine | 1965 |
PLASMA 17-HYDROXYCORTICOSTEROIDS AND 17-OXOSTEROIDS IN PATIENTS WITH BREAST CANCER AND IN NORMAL WOMEN.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Blood; Breast Neoplasms; Female; Humans; Neoplasm Metastasis; Urine | 1965 |
A STUDY OF PITUITARY FUNCTION AFTER INTRASELLAR IMPLANTATION OF 90YTTRIUM.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acromegaly; Basal Metabolism; Breast Neoplasms; Cushing Syndrome; Diabetes Mellitus; Gonadotropins; Gonadotropins, Pituitary; Humans; Hypopituitarism; Metyrapone; Pituitary Diseases; Pituitary Gland; Pituitary Irradiation; Thyroid Function Tests; Urine; Yttrium Isotopes | 1965 |
I. URINARY EXCRETION OF NEUTRAL 17-KETOSTEROIDS AND PREGNANDEIOL BY PATIENTS WITH BREAST CANCER AND BENIGN BREAST DISEASE.
Topics: 17-Ketosteroids; Androsterone; Breast Diseases; Breast Neoplasms; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Menopause; Metabolism; Pregnanediol; Urine | 1965 |
THE DETERMINATION OF 17-OXOSTEROID SULPHATES IN HUMAN PLASMA.
Topics: 17-Ketosteroids; Addison Disease; Adolescent; Adrenalectomy; Androsterone; Blood Chemical Analysis; Breast Neoplasms; Child; Chromatography; Dehydroepiandrosterone; Diabetes Mellitus; Etiocholanolone; Geriatrics; Glucuronates; Humans; Hypogonadism; Obesity; Solvents; Sulfates | 1965 |
[COMPARATIVE STUDY OF PLASMA 17-KETOSTEROIDS AND 17-HYDROXYCORTICOSTEROIDS IN WOMEN WITH BREAST CANCER].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Blood; Breast Neoplasms; Female; Humans; Plasma | 1965 |
[Comparing metabolic studies following infusion of dehydroepiandrosterone sulfate and dehydroepiandrosterone phosphate].
Topics: 17-Ketosteroids; Adult; Androgens; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estriol; Estrone; Etiocholanolone; Female; Humans; Phosphates; Sulfates; Testosterone | 1965 |
[Comparing metabolic studies following infusion of delta-4-androstene-3,17-dione, testosterone phosphate and dehydroepiandrosterone phosphate].
Topics: 17-Ketosteroids; Adult; Androgens; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Estradiol; Estriol; Estrone; Etiocholanolone; Female; Humans; Injections, Intravenous; Middle Aged; Testosterone | 1965 |
[Comparative study of levels of 17-ketosteroids in the peripheral venous, ovarian and adrenal blood drawn in the course of adreno-splenic implantations or adrenalectomies for advanced breast cancer].
Topics: 17-Ketosteroids; Adrenalectomy; Adult; Breast Neoplasms; Cortisone; Humans; In Vitro Techniques; Middle Aged | 1965 |
[Comparative study of plasma and urinary 17-ketosteroids and 17-hydroxycorticosteroids in women with breast cancer].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aged; Breast Neoplasms; Female; Humans; In Vitro Techniques; Middle Aged | 1965 |
Surgical diseases of the adrenal glands.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adrenalectomy; Adult; Breast Neoplasms; Child, Preschool; Cortisone; Cushing Syndrome; Disorders of Sex Development; Female; Humans; Hyperaldosteronism; Infant; Male; Pheochromocytoma; Prednisolone; Virilism | 1965 |
"Urinary 17-ketosteroid excretion study in radiation induced menopause in carcinoma breast".
Topics: 17-Ketosteroids; Adult; Breast Neoplasms; Female; Humans; Menopause; Urine | 1965 |
[Concentration of 17-ketosteroids in the urine of breast cancer patients].
Topics: 17-Ketosteroids; Breast Neoplasms; Chromatography; Female; Humans | 1965 |
[Surgery of the adrenal glands for the treatment of advanced breast cancer].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenalectomy; Breast Neoplasms; Estrogens; Female; Glucocorticoids; Gonadotropins, Pituitary; Humans; Prognosis | 1965 |
URINARY 11-DEOXY-17-OXOSTEROIDS IN BRITISH AND JAPANESE WOMEN WITH REFERENCE TO THE INCIDENCE OF BREAST CANCER.
Topics: 17-Ketosteroids; Asian People; Breast Neoplasms; Ethnicity; Female; Humans; Incidence; Japan; Neoplasms; Thyroid Gland; United Kingdom; Urine; White People | 1964 |
THE RELATION BETWEEN THE URINARY 17-HYDROXYCORTICOSTEROIDS AND 11-DEOXY-17-OXOSTEROIDS AND THE FATE OF PATIENTS AFTER MASTECTOMY.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Aging; Breast Neoplasms; Geriatrics; Humans; Mastectomy; Middle Aged; Pathology; Prognosis; Urine | 1964 |
PITUITARY-ADRENAL FUNCTION FOLLOWING HYPOPHYSECTOMY IN MAN.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Blood Chemical Analysis; Breast Neoplasms; Gonadotropins; Gonadotropins, Pituitary; Humans; Hydrocortisone; Hypophysectomy; Ketones; Metyrapone; Mineralocorticoid Receptor Antagonists; Pituitary Diseases; Pituitary Gland; Pituitary-Adrenal Function Tests; Urine | 1964 |
PLASMA ANDROGENS IN WOMEN. I. NORMAL AND NON-HIRSUTE FEMALES, OOPHORECTOMIZED AND ADRENALECTOMIZED PATIENTS.
Topics: 17-Ketosteroids; Adolescent; Adrenalectomy; Androgens; Androsterone; Blood Chemical Analysis; Breast Neoplasms; Carbon Isotopes; Castration; Chorionic Gonadotropin; Chromatography; Cushing Syndrome; Dehydroepiandrosterone; Dexamethasone; Female; Glucose; Gonadotropins; Humans; Male; Orchiectomy; Ovary; Testosterone | 1964 |
[A CASE OF CUSHING'S SYNDROME IN A 13-YEAR-OLD GIRL WITH FIBROADENOMA OF THE BREAST].
Topics: 17-Ketosteroids; Adenofibroma; Adolescent; Breast; Breast Neoplasms; Cushing Syndrome; Female; Fibroadenoma; Humans; Surgical Procedures, Operative; Urine | 1964 |
HORMONE EXCRETION PATTERNS IN BREAST AND PROSTATE CANCER ARE ABNORMAL.
In patients with breast and prostate cancer hormone excretion patterns differ in a similar way from patterns in persons without cancer. Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Aged; Androsterone; Breast Neoplasms; Creatine; Creatinine; Estradiol; Estriol; Estrone; Etiocholanolone; Gonadotropins; Humans; Male; Menopause; Metabolism; Neoplasms; Pregnanediol; Prostatic Neoplasms; Urine | 1964 |
[STUDY OF FREE AND CONJUGATED BLOOD 17-KETOSTEROIDS IN WOMEN WITH BREAST OR GENITAL EPITHELIOMA].
Topics: 17-Ketosteroids; Adolescent; Blood Chemical Analysis; Breast; Breast Neoplasms; Carcinoma; Female; Humans; Neoplasms; Ovarian Neoplasms; Uterine Neoplasms | 1964 |
DIFFERENTIAL 17-OXOSTEROID EXCRETION IN WOMEN WITH CANCER OF THE BREAST FOLLOWING HYPOPHYSECTOMY.
Topics: 17-Ketosteroids; Androsterone; Breast; Breast Neoplasms; Chromatography; Dehydroepiandrosterone; Etiocholanolone; Female; Glucuronates; Humans; Hypophysectomy; Neoplasm Metastasis; Sulfates; Urine | 1964 |
URINARY STEROID ESTIMATIONS IN THE PREDICTION OF RESPONSE TO ADRENALECTOMY OR HYPOPHYSECTOMY.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenalectomy; Breast Neoplasms; Castration; Female; Fluids and Secretions; Humans; Hypophysectomy; Metabolism; Neoplasms; Ovary; Prognosis; Urine | 1964 |
HORMONAL THERAPY IN CANCER OF THE BREAST. 23. EFFECT OF 7-ALPHA-METHYL-19-NORTESTOSTERONE ACETATE AND TESTOSTERONE PROPIONATE ON CLINICAL COURSE AND HORMONAL EXCRETION.
Topics: 17-Ketosteroids; Acetates; Antineoplastic Agents; Bilirubin; Biomedical Research; Blood Glucose; Breast Neoplasms; Female; Fluids and Secretions; Gonadotropins; Gonadotropins, Pituitary; Humans; Kidney Function Tests; Nandrolone; Neoplasms; Nitrogen; Prolactin; Testosterone; Testosterone Propionate; Toxicology; Transaminases; Urea; Urine; Virilism | 1964 |
DIFFERENCES OF STEROID METABOLISM IN BREAST CANCER AFTER HORMONE STIMULATION.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Androgens; Androsterone; Breast Diseases; Breast Neoplasms; Chemistry Techniques, Analytical; Colorimetry; Dehydroepiandrosterone; Estradiol; Estrone; Etiocholanolone; Humans; Hydrocortisone; Lipid Metabolism; Metabolism; Neoplasms; Spectrum Analysis; Testosterone; Triiodothyronine; Urine | 1964 |
[The effect of intravenously infused ACTH on urine and plasma corticosteroids in mastopathy and breast cancer].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Blood Proteins; Breast Diseases; Breast Neoplasms; Gonadal Steroid Hormones; Humans; Urine | 1964 |
[The behavior of the adrenal cortex in the cancer experiment].
Topics: 17-Ketosteroids; Adrenal Cortex; Animals; Breast Neoplasms; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Neoplasms | 1963 |
The relationship between urinary androst-16-en-3alpha-ol and urinary 11-deoxy-17-oxosteroid excretion.
Topics: 17-Ketosteroids; Anatomy; Androsterone; Breast Neoplasms; Dehydroepiandrosterone; Humans; Testosterone | 1963 |
HORMONAL THERAPY IN CANCER OF THE BREAST. XXII. EFFECT OF 17ALPHA-METHYL-5BETA-DIHYDROTESTOSTERONE ON CLINICAL COURSE AND HORMONAL EXCRETION.
Topics: 17-Ketosteroids; Androgens; Breast; Breast Neoplasms; Creatine; Creatinine; Desoxycorticosterone; Dihydrotestosterone; Gonadotropins; Humans; Luteinizing Hormone; Lymphatic Metastasis; Neoplasms; Pregnanediol; Prolactin; Urine | 1963 |
MEDICAL TREATMENT OF CANCER OF THE BREAST.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenalectomy; Antineoplastic Agents; Breast Neoplasms; Estradiol; Estriol; Estrone; Humans; Neoplasms; Prednisolone; Pregnanediol; Sterilization; Sterilization, Reproductive; Testosterone | 1963 |
[STEROID METABOLISM AFTER ORAL AND INTRAVENOUS ADMINISTRATION OF CORTISONE AND HYDROCORTISONE IN MASTOPATHY AND BREAST CANCER].
Topics: 17-Ketosteroids; Administration, Intravenous; Breast Diseases; Breast Neoplasms; Cortisone; Estradiol Congeners; Estrogens; Humans; Hydrocortisone; Injections, Intravenous; Metabolism; Urine | 1963 |
[EXCRETION OF GONADOTROPINS, ESTROGENS AND 17-KETOSTEROIDS IN SOME PRECANCEROUS AND CANCEROUS DISEASES. BREAST CANCER; DYSFUNCTIONAL UTERINE HEMORRHAGE].
Topics: 17-Ketosteroids; Adenofibroma; Breast Neoplasms; Estrogens; Female; Gonadotropins; Humans; Ovary; Uterine Hemorrhage | 1963 |
Effect of hypophysectomy on components of 17-ketosteroids in patients with breast carcinoma.
Topics: 17-Ketosteroids; Breast Neoplasms; Gonadotropins; Gonadotropins, Pituitary; Humans; Hypophysectomy; Pituitary Diseases; Pituitary Gland | 1962 |
[The ratio of urinary estrogens to 17-ketosteroids in chronic cystic mastits and in breast cancer, with special reference to the various histological features].
Topics: 17-Ketosteroids; Breast Neoplasms; Contraceptive Agents, Female; Estradiol Congeners; Estrogens; Female; Humans; Mastitis | 1961 |
Further observations on the effect of hypophysectomy on the urinary excretion of 17-oxosteroids.
Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Breast; Breast Neoplasms; Humans; Hypophysectomy; Mastectomy; Steroids | 1960 |
[Steroid metabolism in breast cancer. III. The excretion of fractionated 17-ketosteroids as well as testosterone overflow in graduated testosterone load].
Topics: 17-Ketosteroids; Body Fluids; Breast Neoplasms; Humans; Lipid Metabolism; Steroids; Testosterone | 1959 |
[Metabolic aspects & physiopathological findings in patients subjected to bilateral castration & adrenalectomy for cancer of the breast & prostate in advanced stage. I. Behavior of several urinary steroids, of circulating eosinophils & blood phosphatases]
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenalectomy; Breast Neoplasms; Castration; Eosinophils; Humans; Leukocyte Count; Male; Mastectomy; Phosphoric Monoester Hydrolases; Prostatic Neoplasms | 1958 |
Effect of endocrine ablative surgery on the urinary excretion of 17-ketosteroids in advanced cancer of the breast.
Topics: 17-Ketosteroids; Adrenalectomy; Breast; Breast Neoplasms; Humans; Hypophysectomy; Pituitary Gland | 1958 |
The excretion of 17-ketosteroids in the urine of patients with generalised carcinomatosis secondary to carcinoma of the breast.
Topics: 17-Ketosteroids; Breast; Breast Neoplasms; Carcinoma; Humans; Steroids | 1957 |
The excretion of pituitary gonadotrophins, oestrogens, pregnanediol and neutral 17-ketosteroids in the urine of patients with metastatic and recurrent mammary carcinoma.
Topics: 17-Ketosteroids; Breast; Breast Neoplasms; Estrogens; Gonadotropins; Gonadotropins, Pituitary; Humans; Neoplasm Recurrence, Local; Pregnanediol; Steroids | 1957 |
[Steroid metabolism in breast cancer. I. Comparative research on excretory relations of 17-ketosteroids using fractionated hydrolysis and adsorption chromatography].
Topics: 17-Ketosteroids; Adsorption; Breast; Breast Neoplasms; Chromatography; Hormones; Humans; Hydrolysis; Research | 1957 |
[Considerations of 1246 determinations of 17-ketosteroids in 1017 patients with mammary and gynecological pathology; malignant or benign tumors].
Topics: 17-Ketosteroids; Breast; Breast Neoplasms; Female; Genitalia; Genitalia, Female; Humans; Neoplasms; Steroids | 1956 |
[The value of 17-ketosteroids in breast carcinoma].
Topics: 17-Ketosteroids; Body Fluids; Breast Neoplasms; Humans; Steroids; Urine | 1953 |
[Fibroadenoma of the breast and 17-ketosteroids].
Topics: 17-Ketosteroids; Adenofibroma; Breast; Breast Neoplasms; Fibroadenoma; Humans; Steroids; Urine | 1953 |
[Urinary 17-ketosteroid level in differential diagnosis of mastosis and mammary carcinoma].
Topics: 17-Ketosteroids; Body Fluids; Breast Neoplasms; Diagnosis, Differential; Humans; Steroids; Urinary Tract; Urine | 1953 |