17-ketosteroids and Anorexia-Nervosa

Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Aging; Aldehyde-Lyases; Androgens; Androstenediol; Animals; Anorexia Nervosa; Breast Neoplasms; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Estrogens; Fasting; Female; Glucocorticoids; Humans; Hypophysectomy; Japan; Menopause; Middle Aged; Obesity; Prolactin; Puberty; Steroid 17-alpha-Hydroxylase; Stress, Physiological; Sulfotransferases; Sulfurtransferases; Surgical Procedures, Operative; United States

Topics: 17-Ketosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Amenorrhea; Anorexia; Anorexia Nervosa; Basal Metabolism; Body Temperature Regulation; Cholesterol; Dopamine; Female; Gonadotropins; Growth Hormone; Humans; Hypothalamus; Prolactin; Starvation; Thyroid Gland; Vasopressins

Based on a review of the pathophysiology of the major symptoms of anorexia nervosa, it was suggested that increased activity of dopamine at central dopamine receptors plays a role in the pathophysiology of this disorder. Although dopamine receptor site hypersensitivity, or synthesis, of a false transmitter could account for this, a defect in negative feedback control mechanisms is more consistent with the known characteristics of anorexia nervosa. The possible role of pure dopamine antagonists in symptomatic treatment and of dopamine agonists in reversing this disorder was discussed.

Topics: 17-Ketosteroids; Amphetamine; Anorexia Nervosa; Apomorphine; Compulsive Personality Disorder; Dopamine; Female; Glucose Tolerance Test; Gonadotropins, Pituitary; Humans; Levodopa; Luteinizing Hormone; Male; Movement Disorders; Parkinson Disease; Schizophrenia; Steroids; Thinness

Topics: 17-Ketosteroids; Adolescent; Adult; Anorexia Nervosa; Body Weight; Female; Gonadotropin-Releasing Hormone; Humans; Hydrocortisone; Insulin; Pituitary Hormones, Anterior; Thyrotropin-Releasing Hormone; Triiodothyronine

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Anorexia Nervosa; Circadian Rhythm; Dexamethasone; Fasting; Female; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Metyrapone; Middle Aged; Nutrition Disorders; Pituitary-Adrenal System; Psychophysiologic Disorders

Four women with anorexia nervosa were treated with synthetic LH-releasing hormone (LRH) in an attempt to induce ovulation. All the women had very low pretreatment levels of gonadotropins and estrogens. Administration of LRH resulted in significant gonadotropin increases. The FSH response to LRH in relation to the LH response was higher than in regularly menstruating women. LRH (500 mug) was administered parenterally three times daily over about 4 weeks. During this period there were no significant effects on mood, eating behavior, weight, or libido. All the women responded with follicular maturation and ovulation to the prolonged LRH treatment.

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Amenorrhea; Anorexia Nervosa; Anovulation; Body Temperature; Estradiol; Estrogens; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Luteinizing Hormone; Ovarian Follicle; Ovulation; Pregnancy; Progesterone; Testosterone

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adult; Amenorrhea; Anorexia Nervosa; Body Weight; Circadian Rhythm; Female; Humans; Hypothalamo-Hypophyseal System; Metyrapone; Middle Aged; Pituitary-Adrenal Function Tests; Pituitary-Adrenal System

Topics: 11-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adult; Amenorrhea; Anorexia Nervosa; Blood Pressure; Blood Urea Nitrogen; Body Weight; Carbon Dioxide; Chlorine; Dexamethasone; Female; Follicle Stimulating Hormone; Glucose Tolerance Test; Humans; Hypopituitarism; Luteinizing Hormone; Male; Metyrapone; Middle Aged; Sodium

Topics: 17-Ketosteroids; Adrenal Glands; Adult; Amenorrhea; Anorexia Nervosa; Female; Humans; Hypothalamo-Hypophyseal System; Hypothalamus; Ovary; Pituitary Gland; Prospective Studies; Thyroid Gland

Topics: 17-Ketosteroids; Adolescent; Adult; Amenorrhea; Anorexia Nervosa; Body Weight; Female; Humans; Mental Health; Socioeconomic Factors

Topics: 17-Ketosteroids; Addison Disease; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Glands; Adrenal Insufficiency; Adrenocorticotropic Hormone; Anorexia Nervosa; Cushing Syndrome; Diagnosis, Differential; Female; Fluorometry; Hirsutism; Humans; Hypopituitarism; Injections, Intravenous; Klinefelter Syndrome; Male; Methods; Obesity; Pituitary Neoplasms; Spectrophotometry; Turner Syndrome

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acromegaly; Addison Disease; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adult; Anorexia Nervosa; Child; Child, Preschool; Chromatography; Cushing Syndrome; Disorders of Sex Development; Endocrine System Diseases; Female; Humans; Hydrocortisone; Hyperaldosteronism; Hyperthyroidism; Hypertrichosis; Hypopituitarism; Male; Middle Aged; Myxedema; Obesity; Pheochromocytoma; Pregnancy; Spectrophotometry

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adult; Animals; Anorexia Nervosa; Biological Assay; Dehydroepiandrosterone; Diet Therapy; Estradiol; Estriol; Estrone; Female; Gonadotropins, Pituitary; Humans; Male; Mice; Urine; Uterus

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Anorexia Nervosa; Brain; Cushing Syndrome; Humans; Hydrocortisone; Hypothalamus; Urine

Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anorexia Nervosa; Basal Metabolism; Blood Chemical Analysis; Blood Pressure; Blood Pressure Determination; Body Weight; Genetics, Medical; Humans; Hypopituitarism; Urine

Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Anorexia Nervosa; Humans; Ketones; Metyrapone; Mineralocorticoid Receptor Antagonists; Physiology; Pituitary Diseases; Pituitary Gland

Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Insufficiency; Anorexia Nervosa; Cushing Syndrome; Dexamethasone; Diabetes Mellitus; Humans; Hyperthyroidism; Periodicity; Pituitary Gland; Pituitary-Adrenal Function Tests; Statistics as Topic; Urine

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anorexia Nervosa; Cosyntropin; Endocrinology; Mineralocorticoid Receptor Antagonists; Pigmentation Disorders; Zinc

Topics: 17-Ketosteroids; Anorexia Nervosa; Cortisone; Endotoxins; Hematinics; Hepatitis; Liver Diseases; Liver Glycogen; Liver Regeneration; Mental Disorders; Stress, Physiological; Toxicology; Vitamin B 12