17-ketosteroids and Adrenal-Gland-Diseases

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; ACTH Syndrome, Ectopic; Addison Disease; Adrenal Gland Diseases; Biomarkers; Colorimetry; Cushing Syndrome; Humans; Reference Values; Thyroid Diseases

Topics: 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adrenal Glands; Adult; Androgens; Androstenedione; Dehydroepiandrosterone; Female; Hirsutism; Humans; Hyperplasia; Middle Aged; Ovarian Diseases; Ovary; Polycystic Ovary Syndrome; Testosterone

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Addison Disease; Adolescent; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Blood Chemical Analysis; Child; Circadian Rhythm; Cushing Syndrome; Female; Humans; Liver Diseases; Male; Middle Aged; Pituitary-Adrenal Function Tests; Pregnancy; Stress, Physiological; Surgical Procedures, Operative; Thyroid Diseases

Topics: 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Child; Child, Preschool; Dehydration; Female; Glucocorticoids; Humans; Hyperplasia; Hypertension; Infant; Infant, Newborn; Male; Mixed Function Oxygenases; Oxidoreductases; Pylorus; Virilism; Vomiting; Water-Electrolyte Balance

Topics: 17-Ketosteroids; Adaptation, Psychological; Addison Disease; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Cortisone; Cushing Syndrome; Dexamethasone; Female; Genitalia, Female; Glucocorticoids; Growth; Humans; Hydrocortisone; Hyperplasia; Male; Pituitary Diseases; Pituitary Gland; Prognosis; Sodium Chloride; Sodium Salicylate

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Androgens; Dehydroepiandrosterone; Female; Follicle Stimulating Hormone; Humans; Hypothalamus; Luteinizing Hormone; Ovary; Pituitary Gland; Polycystic Ovary Syndrome; Pregnenolone; Progesterone; Steroids; Testosterone

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Aged; Blood Chemical Analysis; Carcinoma; Clinical Trials as Topic; Cushing Syndrome; Female; Humans; Hyperplasia; Male; Metyrapone; Middle Aged; Pregnanes

Topics: 17-Ketosteroids; Adenocarcinoma; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Adult; Clinical Trials as Topic; Creatine; Cushing Syndrome; Dexamethasone; Female; Humans; Hydrocortisone; Male; Middle Aged; Pituitary Function Tests

20 patients with hirsutism of different severity were examined to study the diagnostic assertion of the dexamethasone-HCG-test. The results show, that a well defined classification into the different types of hirsutism (adrenal, ovarian, idiopathic and mixed forms) is not possible using hormonal parameters.

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Chorionic Gonadotropin; Dexamethasone; Diagnosis, Differential; Female; Hirsutism; Humans; Mestranol; Ovarian Diseases

Thirty-one cases of idiopathic hirsutism, characterized biochemically in the basal state by increased levels of urinary 3 alpha-androstane-5 alpha, 17 beta-diol and normal levels of the main androgens, were studied. In order to determine a possible etiologic heterogeneity of idiopathic hirsutism, pituitary gonadotropin responses to synthetic luteinizing-releasing hormone (LRH) and adrenal steroid responses to adrenocorticotropic hormone (ACTH) stimulation were evaluated and the results were compared to those in six normal women. On the basis of the results obtained in each hirsute patient after LRH and ACTH tests, two groups were identified. The majority, 23 of 31 hirsute patients (group I), had results similar to those in the control group. In the other eight patients (group II), biologic abnormalities were disclosed and suggested a partial adrenal 11 beta-hydroxylase defect in two patients, an incomplete form of adrenal 3 beta-ol deficiency in one patient, an adrenal hyperreactivity without evident cause in two patients, and polycystic ovary syndrome in association with an adrenal hyperreactivity in three patients. As a group, the eight patients showed ACTH-stimulated increments in testosterone, delta 4-androstenedione, dehydroepiandrosterone, and 17-ketosteroids that were significantly greater (p less than 0.01) than the mean responses in the control group. The conclusion is that some women who previously were designated as having "idiopathic" hirsutism had an adrenal and/or ovarian component to their hyperandrogenism which could be shown only by appropriate dynamic tests.

Topics: 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; Androstenedione; Dehydroepiandrosterone; Female; Gonadotropin-Releasing Hormone; Hirsutism; Humans; Ovarian Cysts; Testosterone

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Glands; Chemistry, Clinical; Female; Humans; Hypogonadism; Male; Ovary; Polycystic Ovary Syndrome; Testis

Endocrine studies in girls with precocious thelarche were compared with those of normal girls of similar ages. Girls with precocious thelarche showed breast development and oestrogenised vaginal smears as the only signs of precocious sexual development. A few of the girls were tall and some had advanced bone ages but these two findings were not consistently present in the same patient. Hormones--such as serum oestradiol, oestrone, delta 4-androstenedione, progesterone, dehydroepiandrosterone (DHEA), follicle-stimulating hormone, luteinising hormone, and prolactin, and urinary 17-ketosteroids--were measured. Only DHEA was different, being higher in girls with precocious thelarche. It is suggested that the high DHEA level may serve as a precursor for conversion to oestrogens in target tissues, breast, and vagina. This mechanism for oestrogenisation had been reported in other patients.

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Age Determination by Skeleton; Body Height; Child; Child, Preschool; Dehydroepiandrosterone; Female; Gonadal Steroid Hormones; Gonadotropins, Pituitary; Humans; Infant; Puberty, Precocious

Forty-two patients ages 15 to 20 years (average 17.3 years) were evaluated for oligomenorrhea. Group I consisted of 19 patients with evidence of androgen excess (hirsutism, clitoromegaly, acne); and Group II included 23 patients without evidence of androgen excess. Sixteen of the 19 patients in Group I had elevated serum LH and normal FSH values. Serum total testosterone concentration was elevated in 12 patients and free T was elevated in one additional patient. In nine patients urinary 17KS excretion was elevated and dexamethasone suppressible. For the purpose of treatment, patients in Group I were divided into three subgroups: IA, polycystic ovary syndrome--12 patients; IB, adrenal block--two patients; IC, combined adrenal and ovarian hyperandrogenism--five patients. Among the 23 Group II patients, four had persistently elevated serum LH and normal FSH values, suggesting PCO; three had menopausal levels of LA and FSH; one had hyperprolactinemia and a depressed floor of the pituitary sella; and the remaining 15 patients had low to normal serum levels of LH and FSH, consistent with hypothalamic suppression. Guidelines for the diagnosis and treatment of adolescents with oligomenorrhea are discussed on the basis of these findings.

Topics: 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adult; Endocrine System Diseases; Female; Gonadotropins, Pituitary; Humans; Menstruation Disturbances; Oligomenorrhea; Polycystic Ovary Syndrome; Testosterone

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Androgen Antagonists; Female; Hirsutism; Humans; Ovarian Diseases; Polycystic Ovary Syndrome; Testosterone

Ketosteroids, the excretory metabolities of adrenal and gonadal steroids, can be analyzed individually in urine by a simple extraction procedure followed by separation and quantitation by the use of gas/liquid chromatography. The ketosteroids quantitatively detected by the technique are androsterone, etiocholanolone, dehydroepiandrosterone, 11-hydroxyandrosterone, 11-hydroxyetiocholanolone, 11-ketandrosterone, and 11-ketoetiocholanolone. Other steroid metabolities detected are pregnanediol, pregnanetriol, delta5-pregnenetriol, and 11-ketopregnanetriol. In comparison with concentrations of these steroids observed in urine specimens collected from healthy individuals, abnormal results occur in specimens from patients with testicular disease, Cushing's syndrome, adrenal hyperplasia, and several types of female hirsutism. Characteristic profiles for each of these diseases are presented.

Topics: 11-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Androsterone; Chemical Fractionation; Chromatography, Gas; Dehydroepiandrosterone; Etiocholanolone; Female; Hirsutism; Humans; Ketosteroids; Male; Pregnanediol; Pregnanetriol; Pregnenes

Topics: 17-Ketosteroids; Adrenal Cortex Diseases; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Medulla; Adult; Cushing Syndrome; Dexamethasone; Epinephrine; Female; Humans; Middle Aged; Norepinephrine; Pheochromocytoma

Many women have some facial hair, and most patients who seek advice will be at the far end of the normal distribution curve for hair. In a second group there is a slight excessive production of androgens with associated hirsutism, either idiopathic or associated with polycystic ovarian disease. An extremely small fraction of patients will have serious disorders of the adrenals or ovaries and significant elevations in androgen levels.

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Glands; Androgens; Estrogens; Female; Glucocorticoids; Hirsutism; Humans; Ovarian Diseases; Ovary; Progesterone; Testosterone

An improved method for the simultaneous gas-chromatographic determination of individual 17-oxosteroids and of pregnanediol in the same sample of urine is described. The method involves the following steps. The urinary sample is chromatographed on Amberlite XAD-2. The fraction containing the steroid conjugates is evaporated; the residue is dissolved in n-heptane and the organic phase extracted with water. The steroid glucuronides are hydrolysed by a bacterial beta-glucuronidase; subsequently, the steroid sulphates are solvolysed in ethyl acetate. Free 17-oxosteroids and pregnanediol are separated by two-dimensional thin-layer chromatography. The zone containing the steroids to be investigated is eluted; after evaporation, the residue is treat with N-methyl N-trimethyl silyl trifluoroacetamide. The reaction mixture is injected into a gas chromatograph; the trimethyl silyl ethers of the individual 17-oxosteroids and of pregnanediol are quantitated by measuring the peak heights.

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Chromatography, Gas; Chromatography, Liquid; Chromatography, Thin Layer; Humans; Pregnanediol

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Female; Genital Diseases, Female; Humans; Ovarian Diseases; Virilism

Ninety-three infertile women were treated with clomiphene citrate alone or in combination with human chorionic gonadotropin (hCG) for absent or infrequent ovulation. The patients were divided into eight categories according to the diagnosis obtained: ovarian androgenic hyperplasia, adrenal androgenic hyperplasia, mixed ovarian and adrenal androgenic hyperplasia, hypothalamic anovulation, postpill anovulation, follicular phase defect, luteal phase defect, and amenorrhea-galactorrhea syndrome. Each group was analyzed individually to compare the ovulation and conception rates and the complications involved. A survey of the data presented in this study shows that the best response was noted in patients with ovarian androgenic hyperplasia. Patients with a functional pathologic adrenal component responded favorably when dexamethasone was used as an adjuvant to clomiphene therapy. Those with hypothalamic anovulation responded better when hCG was added to clomiphene therapy. Women with postpill anovulation as well as those with follicular phase defect were found to be good candidates for clomiphene therapy. In properly selected patients with poor luteal phase defect, hCG secured excellent results both in ovulation and conception. Patients with lactation amenorrhea failed to ovulate when treated with clomiphene alone.

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Amenorrhea; Androgens; Anovulation; Chorionic Gonadotropin; Clomiphene; Contraceptives, Oral; Endometrium; Female; Galactorrhea; Humans; Hyperplasia; Hypothalamus; Infant, Newborn; Infertility, Female; Luteinizing Hormone; Ovarian Diseases; Ovulation; Pregnancy

Twenty-two hirsute women underwent percutaneous adrenal and ovarian vein catheterization to differentiate and localize excessive hormonal output. All studies were done under fluoroscopic control; catheter placement was verified by venography, and blood samples were withdrawn for hormonal analysis. The right ovarian vein was successfully sampled in 42 per cent of attempts; the left ovarian vein, in 75 per cent; the right adrenal vein, in 56 per cent; and the left adrenal vein, in 100 per cent. Bilateral catheterization did not prove clinically useful. First, anatomic variations in venous size and drainage made catheterization and bilateral sampling difficult. Second, adrenal secretion is both episodic and parallel, necessitating both simultaneous catheterization and serial sampling for adequate diagnosis. The stress of the procedure may provoke increased adrenal output. Third, since ovarian secretion is not parallel, and since increased hormone output has been documented in that ovary containing developing follicles or a corpus luteum, distinguishing ovarian dysfunction proved difficult. Finally, for a time-consuming procedure, patient discomfort cannot be disregarded. This technique has not proved to be a reliable means of determining the site of androgen hypersecretion and thus cannot be recommended in the routine evaluation of female hirsutism.

Topics: 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adrenal Glands; Adult; Androstenedione; Catheterization; Female; Hirsutism; Humans; Hydrocortisone; Ovarian Diseases; Ovary; Testosterone; Veins

Five new patients with postmenarchial onset of adrenal virilism related to 21-hydroxylase deficiency are presented. Diagnostic criteria are reviewed. Four pregnancies resulting in 3 term infants occurred after instigation of therapy. Eleven patients similar in clinical presentation are reviewed for comparison. Findings of value in distinguishing these two groups of patients are discussed.

Topics: 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Child; Dexamethasone; Female; Hirsutism; Humans; Hydroxysteroids; Menarche; Metabolism, Inborn Errors; Mixed Function Oxygenases; Prednisone; Pregnancy; Pregnanetriol; Time Factors; Virilism

Seven oophorectomized patients were administered a total of 60,000 units of human chorionic gonadotropin over a 3-day period, and plasma testosterone levels were obtained. One of the 7 patients demonstrated a definitive response to the hormone but repeat testing proved to be negative. The potential role of luteinizing hormone in the pathogenesis of polycystic ovarian syndrome is discussed and current evidence linking LH to adrenal androgenesis is reviewed. Modifications that may be employed for future study are suggested.

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adult; Androgens; Castration; Chorionic Gonadotropin; Estrogens; Female; Follicle Stimulating Hormone; Humans; Injections, Intramuscular; Luteinizing Hormone; Middle Aged; Polycystic Ovary Syndrome; Radioimmunoassay; Testosterone

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Androgens; Cyproterone; Dexamethasone; Diethylstilbestrol; Female; Hirsutism; Humans; Ovarian Neoplasms

Topics: 11-Hydroxycorticosteroids; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adult; Androstenedione; Androsterone; Carcinoma; Chromatography, Ion Exchange; Cushing Syndrome; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Hyperplasia; Male; Middle Aged; Sex Factors; Tetrahydrocortisol

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Age Determination by Skeleton; Angiography; Back Pain; Bone Diseases; Cortisone; Cushing Syndrome; Dexamethasone; Female; Fludrocortisone; Humans; Hydrocortisone; Male; Radioimmunoassay; Rib Fractures

Topics: 17-Ketosteroids; Addison Disease; Adrenal Cortex; Adrenal Gland Diseases; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Circadian Rhythm; Cushing Syndrome; Dexamethasone; Female; Humans; Hydrocortisone; Hydroxyprogesterones; Hyperplasia; Insulin; Male; Metyrapone; Middle Aged; Radiography; Skull; Sodium; Steroid Hydroxylases; Time Factors

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Cortex Diseases; Adrenal Gland Diseases; Adult; Child; Child, Preschool; Dexamethasone; Female; Humans; Infant; Middle Aged; Pregnancy

Topics: 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adult; Child; Cortisone; Female; Follicle Stimulating Hormone; Humans; Hyperplasia; Luteinizing Hormone; Menstruation Disturbances; Water-Electrolyte Balance

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adult; Child; Child, Preschool; Circadian Rhythm; Corticosterone; Dexamethasone; Female; Humans; Hyperplasia; Middle Aged; Pregnanetriol; Progesterone; Spectrometry, Fluorescence

Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Diseases; Body Height; Body Weight; Cortisone; Cushing Syndrome; Female; Fludrocortisone; Humans; Hydrocortisone; Hyperplasia; Metyrapone; Mitotane

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Blood Glucose; Calcium; Desoxycorticosterone; Dexamethasone; Diseases in Twins; Fludrocortisone; Growth Hormone; Humans; Hydrocortisone; Infant, Newborn; Insulin; Luteinizing Hormone; Male; Pituitary-Adrenal Function Tests; Posture; Potassium; Thyrotropin; Thyroxine

Topics: 11-Hydroxycorticosteroids; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Dexamethasone; Humans; Methods; Pituitary-Adrenal Function Tests

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Child; Cholesterol; Chromatography, Gas; Electrophoresis, Paper; Female; Humans; Hyperplasia; Lipoproteins; Spectrum Analysis; Triglycerides

Topics: 11-Hydroxycorticosteroids; 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adult; Aged; Child; Female; Humans; Male; Middle Aged

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Chromatography, Gas; Chromatography, Thin Layer; Cushing Syndrome; Female; Hirsutism; Humans; Infertility, Female; Male; Pregnanetriol

Topics: 17-Ketosteroids; Abdominal Neoplasms; Abnormalities, Multiple; Adrenal Gland Diseases; Adrenal Glands; Antigens; Blood Glucose; Female; Hernia, Umbilical; Humans; Hyperplasia; Hypoglycemia; Infant, Newborn; Insulin; Kidney Diseases; Leucine; Pancreas; Pancreatectomy; Time Factors; Tongue; Umbilicus

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Androgens; Chemistry Techniques, Analytical; Chromatography, Thin Layer; Diagnosis, Differential; Female; Humans

Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adult; Amenorrhea; Female; Hirsutism; Humans; Hyperplasia; Metabolism, Inborn Errors; Middle Aged; Mixed Function Oxygenases; Ovarian Cysts; Ovarian Diseases; Ovarian Neoplasms; Polycystic Ovary Syndrome; Pregnanetriol; Testosterone

Topics: 17-Ketosteroids; Abdomen; Adrenal Gland Diseases; Adult; Androstanes; Dehydroepiandrosterone; Female; Hirsutism; Humans; Male; Middle Aged; Ovarian Diseases; Protein Binding; Skin; Testosterone

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Insufficiency; Adrenocorticotropic Hormone; Aldosterone; Clinical Laboratory Techniques; Cushing Syndrome; Electrolytes; Humans; Hydrocortisone; Hypopituitarism; Pituitary-Adrenal Function Tests; Testosterone

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Body Height; Child; Child, Preschool; Corticosterone; Dexamethasone; Estrogens; Female; Follicle Stimulating Hormone; Hair; Humans; Hydrocortisone; Hyperplasia; Indicator Dilution Techniques; Karyotyping; Luteinizing Hormone; Male; Metabolism, Inborn Errors; Mixed Function Oxygenases; Ovary; Testosterone; Uterus

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Chorionic Gonadotropin; Chromatography; Chromatography, Gas; Culdoscopy; Dexamethasone; Female; Hirsutism; Humans; Hydrocortisone; Laparoscopy; Ovarian Diseases; Ovary; Pregnanediol; Pregnanetriol

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acromegaly; Adrenal Gland Diseases; Bone Diseases; Cushing Syndrome; Dwarfism, Pituitary; Endocrine System Diseases; Female; Gigantism; Growth Hormone; Humans; Male; Ossification, Heterotopic; Pituitary Diseases; Radiography; Thyroid Diseases; Thyroid Hormones

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Hyperfunction; Adult; Cushing Syndrome; Dexamethasone; Female; Glucocorticoids; Humans; Hyperplasia; Middle Aged; Pituitary Irradiation; Postoperative Care; Postoperative Complications; Radiography

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adult; Androgens; Female; Hirsutism; Humans; Male; Methods; Testosterone

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Androgens; Female; Hirsutism; Humans; Menopause; Ovarian Diseases; Polycystic Ovary Syndrome; Vaginal Smears; Virilism

Topics: 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adult; Amenorrhea; Body Constitution; Diabetes Complications; Dysmenorrhea; Endometrium; Estrone; Female; Fertility; Gonadotropins; Humans; Menarche; Menstruation Disturbances; Middle Aged; Ovarian Diseases; Pituitary Diseases; Pregnanediol; Puberty; Sex Chromosome Aberrations; Thyroid Diseases; Uterine Diseases; Vaginal Smears

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Glands; Age Factors; Aged; Diabetes Mellitus; Humans; Hypertension; Male

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Aging; Aldosterone; Androstanes; Androsterone; Child; Child, Preschool; Chlorides; Chromatography, Gas; Chromatography, Thin Layer; Dehydroepiandrosterone; Disorders of Sex Development; Etiocholanolone; Female; Glucuronates; Humans; Hydrocortisone; Hydroxysteroid Dehydrogenases; Hyperkalemia; Hyperplasia; Hyponatremia; Infant; Infant, Newborn; Male; Metabolism, Inborn Errors; Potassium; Pregnanetriol; Pregnenolone; Sodium; Sulfates; Testosterone

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Female; Humans; Male; Middle Aged; Multiple Sclerosis

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Androstenols; Estrogens; Female; Follicle Stimulating Hormone; Genital Diseases, Female; Hirsutism; Hormones; Humans; Hyperplasia; Luteinizing Hormone; Pregnancy; Pregnancy Complications; Pregnanediol; Testosterone

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Alcohols; Androstanes; Androsterone; Child, Preschool; Chromatography, Gas; Etiocholanolone; Female; Hirsutism; Humans; Hydrocortisone; Hyperplasia; Male; Pregnanediol; Pregnanetriol; Stereoisomerism

Topics: 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adult; Androgens; Drug Antagonism; Estrogens; Female; Hirsutism; Humans; Menstruation; Models, Biological; Ovary; Vagina; Vaginal Smears

Topics: 17-Ketosteroids; Abnormalities, Multiple; Adrenal Gland Diseases; Blood Chemical Analysis; Chromosome Aberrations; Chromosome Disorders; Diagnosis, Differential; Glucose Tolerance Test; Growth Hormone; Hernia, Umbilical; Humans; Hypoglycemia; Infant; Kidney Diseases; Male; Tongue; Umbilicus; Urine

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Androgens; Chromatography, Gas; Collagen Diseases; Cushing Syndrome; Dehydroepiandrosterone; Dexamethasone; Etiocholanolone; Female; Glucuronidase; Humans; Hyperthyroidism; Hypogonadism; Liver Cirrhosis; Male; Metyrapone; Pregnanes; Sterols

Topics: 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Androgens; Androstanes; Female; Glucocorticoids; Humans; Hydrocortisone; Hyperplasia; Testosterone

Topics: 17-Ketosteroids; Addison Disease; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Glands; Adrenal Insufficiency; Adrenocorticotropic Hormone; Anorexia Nervosa; Cushing Syndrome; Diagnosis, Differential; Female; Fluorometry; Hirsutism; Humans; Hypopituitarism; Injections, Intravenous; Klinefelter Syndrome; Male; Methods; Obesity; Pituitary Neoplasms; Spectrophotometry; Turner Syndrome

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Child, Preschool; Female; Humans; Hyperplasia; Infant, Newborn; Male; Pregnanetriol; Testosterone

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Cesarean Section; Clitoris; Corticosterone; Dexamethasone; Female; Humans; Hydrocortisone; Pregnancy; Pregnancy Complications; Pregnanediol; Pregnanetriol

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Fluorometry; Humans; Hydrocortisone; Spironolactone

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Aged; Body Weight; Catheterization; Dexamethasone; Female; Hirsutism; Humans; Middle Aged; Phlebography; Prednisone; Testosterone; Veins; Virilism

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Carcinoma; Cushing Syndrome; Diagnosis, Differential; Humans; Hyperplasia; Precancerous Conditions

Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Androgens; Child; Female; Humans; Hydrocortisone; Hyperplasia; Hyponatremia; Infant; Male; Metabolism, Inborn Errors; Progestins

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Child; Female; Glucocorticoids; Humans; Infant; Infant, Newborn; Male; Potassium; Sodium; Virilism

Topics: 17-Ketosteroids; Addison Disease; Adolescent; Adrenal Gland Diseases; Androgens; Child; Child, Preschool; Clomiphene; Dehydroepiandrosterone; Humans; Hypogonadism; Male; Puberty; Sulfates; Testosterone

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acanthosis Nigricans; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Dexamethasone; Endocrine System Diseases; Female; Humans; Male; Obesity; Pituitary Diseases; Steroids

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aldosterone; Androgens; Estradiol; Estrogens; Estrone; Female; Humans; Hydrocortisone; Hyperplasia; Male; Middle Aged; Testosterone

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acute Disease; Adrenal Gland Diseases; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Feedback; Humans; Hydrocortisone; Male; Pituitary-Adrenal Function Tests; Stress, Physiological; Surgical Procedures, Operative

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acute Disease; Adrenal Gland Diseases; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Feedback; Humans; Hydrocortisone; Male; Pituitary-Adrenal Function Tests; Stress, Physiological; Surgical Procedures, Operative

Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Age Factors; Child; Cushing Syndrome; Humans; Hyperplasia; Male; Pituitary-Adrenal Function Tests

Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Dexamethasone; Humans; Hyperplasia; Hypothalamo-Hypophyseal System; Male; Pituitary-Adrenal System

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Glands; Aldosterone; Animals; Dogs; Growth; Hyperplasia; Metyrapone; Microscopy, Electron; Natriuresis; Pregnanes; Sodium

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Animals; Diabetes Mellitus; Dog Diseases; Dogs; Female; Hyperinsulinism; Hypothyroidism; Male; Metyrapone; Pituitary-Adrenal Function Tests; Pituitary-Adrenal System

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Glands; Adrenocorticotropic Hormone; Dexamethasone; Diagnosis, Differential; Female; Glucocorticoids; Hirsutism; Humans; Hyperplasia; Menstruation Disturbances; Pregnanetriol; Virilism

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; Asthma; Female; Humans; Injections, Intramuscular; Male; Staphylococcal Infections

Topics: 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Dexamethasone; Female; Humans; Hyperplasia; Male; Metyrapone; Pituitary-Adrenal Function Tests; Pregnanes

Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenocortical Hyperfunction; Adult; Child; Child, Preschool; Cortisone; Dexamethasone; Estradiol; Estriol; Estrone; Female; Follicle Stimulating Hormone; Gonadotropins, Pituitary; Humans; Hyperplasia; Luteinizing Hormone; Male; Pituitary-Adrenal System; Prednisolone; Pregnanediol; Pregnanetriol

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Chromatography, Thin Layer; Female; Humans; In Vitro Techniques; Male; Methods; Spectrophotometry

Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Insufficiency; Aminoglutethimide; Aniline Compounds; Anticonvulsants; Cushing Syndrome; Female; Hematoma; Hirsutism; Humans; Hyperaldosteronism; Hypothyroidism; Male; Necrosis; Pyridones

Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adult; Androstanes; Chromatography, Thin Layer; Coloring Agents; Densitometry; Humans; Infant, Newborn; Pregnanes; Pregnanetriol; Tetrazolium Salts

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenalectomy; Adult; Humans; Lumbosacral Region; Methods; Plethysmography; Sympathectomy; Thromboangiitis Obliterans

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Child, Preschool; Chromatography; Clitoris; Female; Humans; Hyperplasia; Hypertension; Infant; Infant, Newborn; Infant, Newborn, Diseases; Male; Methyldopa; Steroids; Virilism

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adult; Humans; Hydrocortisone; Male; Middle Aged; Myocardial Infarction

Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Estrogens; Female; Hirsutism; Humans; Ovarian Diseases; Testosterone

Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Diagnosis, Differential; Female; Humans; Ovarian Diseases; Pituitary-Adrenal Function Tests

Topics: 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adult; Chorionic Gonadotropin; Dexamethasone; Diagnosis, Differential; Female; Hirsutism; Humans; Luteinizing Hormone; Ovarian Diseases; Ovary; Pituitary-Adrenal Function Tests

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Dexamethasone; Diagnosis, Differential; Female; Hirsutism; Humans; Luteinizing Hormone; Ovarian Diseases; Pregnanediol; Pregnanetriol

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Androsterone; Chromatography, Gas; Dehydroepiandrosterone; Etiocholanolone; Female; Humans; Polycystic Ovary Syndrome; Pregnancy

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Cushing Syndrome; Dehydroepiandrosterone; Female; Hirsutism; Humans; Hyperplasia; Infertility, Female; Male; Polycystic Ovary Syndrome; Testosterone

The plasma concentration, production rate, and conversion ratio of androstenedione and testosterone were studied in seven children with congenital adrenal hyperplasia (CAH) of the 21-hydroxylase type. Plasma androstenedione and testosterone measured by double isotope derivative assay and estimated blood production rates were manyfold increased in the untreated state, markedly suppressed with glucocorticoid, and increased after the administration of ACTH. The metabolic clearance rate when corrected for body size and the conversion ratio of androstenedione to testosterone were similar to previously determined values in normal adults. Consideration of the androgen concentrations and conversion ratios indicates that in children with CAH, 76% of the plasma testosterone in prepubertal females and 36% in males are derived from peripheral conversion of blood androstenedione. The calculated amount of testosterone unaccounted for by peripheral conversion is similar to normal prepubertal values. This approach indicates that virilization in these children results from increased levels of testosterone but that the major source in CAH of this potent androgen is androstenedione secreted by the adrenal cortex.

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Child; Child, Preschool; Female; Glucocorticoids; Humans; Hyperplasia; Male; Testosterone

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adult; Androsterone; Dehydroepiandrosterone; Female; Hirsutism; Humans; Hyperplasia; Middle Aged; Prednisone

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Glands; Adrenocorticotropic Hormone; Dexamethasone; Diagnosis, Differential; Humans; Methods; Vasopressins

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Aldosterone; Angiotensin II; Humans; Minerals

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Addison Disease; Adrenal Gland Diseases; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Animals; Cushing Syndrome; Estradiol; Female; Humans; Hydrocortisone; Middle Aged; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnanetriol; Rats

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; Child; Female; Humans; Male

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adult; Androsterone; Carbon Disulfide; Etiocholanolone; Humans; Male; Testicular Diseases

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Child; Cushing Syndrome; Dichlorodiphenyldichloroethane; Electroencephalography; Female; Humans; Hyperplasia

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Glands; Adult; Aged; Cholecystitis; Female; Humans; Male; Middle Aged

Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Humans; Infant, Newborn; Infant, Newborn, Diseases; Pituitary-Adrenal Function Tests

Topics: 17-Ketosteroids; Addison Disease; Adrenal Gland Diseases; Adrenal Glands; Adrenal Hyperplasia, Congenital; Female; Humans; Hypopituitarism; Male; Pituitary-Adrenal Function Tests

Topics: 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Amenorrhea; Androgen-Insensitivity Syndrome; Disorders of Sex Development; Estrogens; Female; Gonadotropins, Pituitary; Humans; Hypogonadism; Ovarian Diseases; Turner Syndrome

Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Blood Chemical Analysis; Body Fluids; Diagnosis; Fluids and Secretions; Hydrocortisone; Ketones; Metyrapone; Mineralocorticoid Receptor Antagonists; Pituitary-Adrenal Function Tests; Radioisotopes; Urine

Topics: 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adrenogenital Syndrome; Child; Chromatography; Humans; Hyperplasia; Infant; Metabolism; Urine

Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adrenalectomy; Adult; Breast Neoplasms; Child, Preschool; Cortisone; Cushing Syndrome; Disorders of Sex Development; Female; Humans; Hyperaldosteronism; Infant; Male; Pheochromocytoma; Prednisolone; Virilism

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Female; Hirsutism; Humans; Male; Ovarian Neoplasms; Testosterone; Virilism

Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenalectomy; Adrenocortical Hyperfunction; Adrenogenital Syndrome; Aldosterone; Androgens; Cushing Syndrome; Humans; Hyperplasia; Hypertrophy; Pathology; Pituitary-Adrenal Function Tests; Sympatholytics

Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Insufficiency; Anorexia Nervosa; Cushing Syndrome; Dexamethasone; Diabetes Mellitus; Humans; Hyperthyroidism; Periodicity; Pituitary Gland; Pituitary-Adrenal Function Tests; Statistics as Topic; Urine

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenocortical Hyperfunction; Adrenogenital Syndrome; Dexamethasone; Fatigue; Fever; Humans; Hyperplasia; Male; Pituitary-Adrenal Function Tests; Prednisone; Urine

Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Aldosterone; Biomedical Research; Blood; Child; Creatine; Creatinine; Diet, Sodium-Restricted; Humans; Infant; Infant, Newborn; Natriuresis; Pregnanediol; Pregnanetriol; Sodium; Sodium, Dietary; Steroids

Topics: 17-Ketosteroids; Acromegaly; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Androgens; Chromatography; Ketones; Metabolism; Mineralocorticoid Receptor Antagonists; Pituitary-Adrenal Function Tests; Urine

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Cortex; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adrenogenital Syndrome; Androsterone; Blood Chemical Analysis; Child; Dehydroepiandrosterone; Humans; Hyperplasia; Pituitary-Adrenal Function Tests; Testosterone; Urine

Topics: 17-Ketosteroids; Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adrenogenital Syndrome; Cholesterol; Chromatography; Dehydroepiandrosterone; Dexamethasone; Drug Therapy; Gonadotropins; Humans; Hydrocortisone; Lipids; Male; Pathology; Puberty; Puberty, Precocious; Sexual Maturation; Surgical Procedures, Operative; Urine

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; 3-Hydroxysteroid Dehydrogenases; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Child; Dehydroepiandrosterone; Estriol; Histocytochemistry; Humans; Hydroxysteroid Dehydrogenases; Hyperplasia; Hypospadias; Infant; Infant, Newborn; Male; Mixed Function Oxygenases; Pathology; Testis; Urine

Topics: 17-Ketosteroids; Acetylcholine; Adrenal Gland Diseases; Biochemical Phenomena; Biochemistry; Blood Protein Electrophoresis; Capillaries; Epinephrine; Humans; Hyperparathyroidism; Hyperthyroidism; Onychomycosis; Serum Albumin; Serum Globulins; Trichophyton; Urine

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adrenogenital Syndrome; Blood; Cushing Syndrome; Estrogens; Humans; Hyperplasia; Pharmacology; Pregnanetriol; Triamcinolone; Urine

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Addison Disease; Adrenal Cortex; Adrenal Gland Diseases; Adrenal Insufficiency; Adrenocortical Hyperfunction; Androsterone; Cushing Syndrome; Dehydroepiandrosterone; Humans; Hydrochlorothiazide; Hypoadrenocorticism, Familial; Hypopituitarism; Pharmacology; Pituitary-Adrenal Function Tests

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adrenogenital Syndrome; Anatomy; Etiocholanolone; Fever; Hyperplasia

Topics: 17-Ketosteroids; Adrenal Cortex; Adrenal Gland Diseases; Adrenal Insufficiency; Adrenocortical Hyperfunction; Adrenogenital Syndrome; Humans; Hyperplasia; Infant; Infant, Newborn; Infant, Newborn, Diseases; Metabolic Diseases; Sodium Chloride

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Humans; Iodine Isotopes; Pituitary Gland; Rhinitis; Rhinitis, Atrophic; Thyroid Diseases; Urine

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Angiography; Asphyxia Neonatorum; Blood Chemical Analysis; Calcification, Physiologic; Dextrocardia; Electrocardiography; Heart Defects, Congenital; Humans; Infant; Infant, Newborn; Radiography; Transposition of Great Vessels; Urine; Urography

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Blood Chemical Analysis; Chromatography; Cortisone; Cushing Syndrome; Dexamethasone; Humans; Hydrocortisone; Neoplasms; Pharmacology; Pituitary-Adrenal Function Tests; Urine

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adrenogenital Syndrome; Hirsutism; Hypertrichosis; Mineralocorticoid Receptor Antagonists; Pituitary-Adrenal Function Tests; Pregnanediol; Urine

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Female; Humans; Hyperplasia; Hypertrophy; Puberty; Puberty, Precocious; Sexual Maturation; Tooth; Urine; Virilism

Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Blood Pressure Determination; Cushing Syndrome; Diagnosis, Differential; Endocrinology; Estrogens; Ketones; Metyrapone; Mineralocorticoid Receptor Antagonists; Urine

Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Androsterone; Cushing Syndrome; Estradiol; Estriol; Estrogens; Estrone; Etiocholanolone; Female; Hirsutism; Humans; Hypertrichosis; Ovary; Pregnanediol; Steroids; Urine; Virilism

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adrenocortical Hyperfunction; Cushing Syndrome; Humans; Hyperplasia

Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Glands; Disease; Humans; Steroids; Syndrome; Urinary Tract; Urine