17-ketosteroids and Acute-Disease

This study compares the efficacy of intravenous adrenocorticotropic hormone (ACTH) with intravenous hydrocortisone in the treatment of patients with symptomatic inflammatory bowel disease. Drug doses were pharmacologically equivalent on the basis of achieved plasma cortisol levels and continuously monitored urinary corticoid excretion rates. Drug selection and patient evaluation were accomplished with a random double blind technique. Evaluation of 22 consecutive hospital patients indicates that ACTH and hydrocortisone, when administered intravenously in pharmacologically equivalent dosage, are therapeutically equivalent, that response to ACTH is rapid, with no therapeutic lag, and that differences in therapeutic responses cannont be corrrelated with differences in systemic steroid levels.

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acute Disease; Adrenocorticotropic Hormone; Clinical Trials as Topic; Colitis; Colitis, Ulcerative; Crohn Disease; Humans; Hydrocortisone; Time Factors

In 110 patients with acute pancreatitis the authors studied the activity of intracellular enzymes in the blood (LDH, CPC, ALaT, ASaT, transamidinase) in a complex with indices characterizing the condition of the membrane cell systems, in particular: activity of acid phosphatase, content of 17-ketosteroids, activity of plasma chemiluminescence, concentration of beta-lipoproteins in blood. Complex study of these indices makes it possible to make a sufficiently objective judgement of the severity of the membrane disorders in acute pancreatitis and verity the form and control the treatment of the disease.

Topics: 17-Ketosteroids; Acid Phosphatase; Acute Disease; Adolescent; Adult; Aged; Cell Membrane; Creatine Kinase; Enzyme Activation; Female; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lipids; Male; Middle Aged; Pancreatitis; Transaminases

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acute Disease; Adult; Aged; Blood Coagulation; Cholinesterases; Creatine Kinase; Humans; Lipids; Middle Aged; Myocardial Infarction; Reference Values

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acute Disease; Adult; Anxiety Disorders; Chronic Disease; Humans; Male; Schizophrenia

Topics: 17-Ketosteroids; Acute Disease; Adult; Aged; Androgens; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Male; Middle Aged; Myocardial Infarction; Testosterone; Time Factors

Topics: 17-Ketosteroids; Acute Disease; Adrenal Cortex; Adult; Aged; Female; Humans; Male; Middle Aged; Thrombophlebitis

The indices of glucocorticoid and androgen activity in the adrenal cortex (the level of circulating eosinophils, the daily urine excretion of 17 OCS and 17 CS) and the functional reserve after an ACTH loading was studied in 2 groups of patients with disorders of cerebral circulation under 45 years of age (247 cases) and over 55 (234 cases). In the acute period of a cerebral stroke there was an increase of the glucocorticoid activity which was more definitely expressed in the younger group and a certain inhibition of the androgen function seen mainly in the older group. In transient disorders of cerebral circulation significant age difference in the functioning of the adrenal cortex was not established. In the period following a stroke the established and potential reserves of the adrenocortical glands were distinctly decreased in patients above 55 years and practically unchanged in the younger group.

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acute Disease; Adrenal Cortex; Adrenal Glands; Adult; Age Factors; Cerebrovascular Disorders; Eosinophils; Humans; Ischemic Attack, Transient; Middle Aged

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acute Disease; Adrenal Glands; Adult; Aged; Brain; Brain Stem; Cerebellum; Cerebral Hemorrhage; Female; Humans; Ischemia; Ischemic Attack, Transient; Male; Middle Aged; Subarachnoid Hemorrhage; Telencephalon; Time Factors

Topics: 17-Ketosteroids; 5-Aminolevulinate Synthetase; Acute Disease; Adult; Animals; Chromatography, Gas; Cycloheximide; Dactinomycin; Dexamethasone; Female; Glucuronates; Humans; Liver; Male; Middle Aged; Porphobilinogen; Porphyrias; Porphyrins; Rats; Remission, Spontaneous; Sulfuric Acids

Topics: 17-Ketosteroids; Acute Disease; Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Asthma; Child; Creatinine; Eosinophilia; Eosinophils; Glucocorticoids; Humans; Male; Pituitary-Adrenal Function Tests; Uric Acid

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acute Disease; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Androgens; Chromatography, Thin Layer; Chronic Disease; Coronary Disease; Glucocorticoids; Humans; Male; Methods; Middle Aged; Myocardial Infarction; Time Factors

Topics: 17-Ketosteroids; Acute Disease; Adolescent; Adrenal Glands; Adult; Affect; Circadian Rhythm; Defense Mechanisms; Female; Humans; Hydrocortisone; Pituitary-Adrenal Function Tests; Projective Techniques; Schizophrenia

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acute Disease; Adrenocorticotropic Hormone; Adult; Blood Glucose; Diet; Diet Therapy; Dietary Carbohydrates; Glucose Tolerance Test; Growth Hormone; Humans; Insulin; Lactates; Male; Metyrapone; Pituitary-Adrenal Function Tests; Porphyrias; Porphyrins; Pyrroles; Pyruvates

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acute Disease; Adrenal Gland Diseases; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Feedback; Humans; Hydrocortisone; Male; Pituitary-Adrenal Function Tests; Stress, Physiological; Surgical Procedures, Operative

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acute Disease; Adrenal Gland Diseases; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Feedback; Humans; Hydrocortisone; Male; Pituitary-Adrenal Function Tests; Stress, Physiological; Surgical Procedures, Operative

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acute Disease; Adolescent; Adrenal Glands; Adult; Extracellular Space; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Serotonin; Trichinellosis

Topics: 17-Ketosteroids; Acute Disease; Adrenal Cortex Hormones; Adrenal Glands; Adult; Androsterone; Female; Humans; Jaundice; Liver Diseases; Male

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acute Disease; Adrenocorticotropic Hormone; Adult; Chronic Disease; Female; Humans; Hypothalamo-Hypophyseal System; Male; Metyrapone; Middle Aged; Multiple Sclerosis; Neurologic Manifestations; Pituitary-Adrenal Function Tests; Pituitary-Adrenal System; Stimulation, Chemical; Vasopressins

Topics: 17-Ketosteroids; Acute Disease; Adult; Aged; Blood Pressure; Humans; Male; Middle Aged; Myocardial Infarction

Topics: 17-Ketosteroids; Acute Disease; Adrenal Glands; Cerebral Hemorrhage; Cerebrovascular Disorders; Encephalomalacia; Eosinophils; Humans; Hypertension; Intracranial Arteriosclerosis; Intracranial Embolism and Thrombosis; Rheumatic Diseases; Syphilis, Cardiovascular

Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acute Disease; Adolescent; Adult; Aged; Blood Proteins; Female; Humans; Leukemia; Male; Middle Aged

Topics: 17-Ketosteroids; Acute Disease; Adrenal Glands; Adult; Cerebrovascular Circulation; Cerebrovascular Disorders; Eosinophils; Female; Humans; Male; Pituitary-Adrenal Function Tests

Topics: 17-Ketosteroids; Acute Disease; Adrenal Cortex; Leukemia; Pituitary-Adrenal Function Tests; Prognosis

Topics: 17-Ketosteroids; Acute Disease; Body Fluids; Child; Communicable Diseases; Infant; Steroids; Urine