Compounds > 17-hydroxy-4-7-10-13-15-19-docosahexaenoic-acid

17-hydroxy-4-7-10-13-15-19-docosahexaenoic-acid and Anemia--Iron-Deficiency

17-hydroxy-4-7-10-13-15-19-docosahexaenoic-acid has been researched along with Anemia--Iron-Deficiency* in 1 studies

Trials

1 trial(s) available for 17-hydroxy-4-7-10-13-15-19-docosahexaenoic-acid and Anemia--Iron-Deficiency

Article	Year
Low immune cell ARA and high plasma 12-HETE and 17-HDHA in iron-deficient South African school children with allergy. Prostaglandins, leukotrienes, and essential fatty acids, 2016, Volume: 110 Allergy has been associated with altered fatty acid and inflammatory status. In this cross-sectional study of 321 rural iron deficient (ID) South African children (aged 6-11 years), a subsample (n=111) of children with parent-reported allergy data were divided into an allergic (n=30) and non-allergic (n=81) group and compared. PBMC arachidonic acid (ARA; P=0.010) and the PBMC ARA to dihomo-gamma-linolenic acid (DGLA) ratio (P=0.035) were lower in the allergic children. Plasma 12-hydroxyeicosatetraenoic acid and 17-hydroxydocosahexaenoic acid (17-HDHA) were higher (P=0.040 and 0.020, respectively) in the allergic group. Thus, a fatty acid composition and lipid mediator levels indicative of increased release of ARA from PBMC membranes, increased inflammation as well as the resolving thereof, were associated with parent-reported allergy symptoms. This study used baseline data of an intervention study which was registered at clinicaltrials.gov as NCT01092377. Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 8,11,14-Eicosatrienoic Acid; Anemia, Iron-Deficiency; Arachidonic Acid; Child; Cross-Sectional Studies; Docosahexaenoic Acids; Female; Humans; Hypersensitivity; Male; Rural Population; South Africa	2016

Article

Year

Low immune cell ARA and high plasma 12-HETE and 17-HDHA in iron-deficient South African school children with allergy.

Prostaglandins, leukotrienes, and essential fatty acids, 2016, Volume: 110

Allergy has been associated with altered fatty acid and inflammatory status. In this cross-sectional study of 321 rural iron deficient (ID) South African children (aged 6-11 years), a subsample (n=111) of children with parent-reported allergy data were divided into an allergic (n=30) and non-allergic (n=81) group and compared. PBMC arachidonic acid (ARA; P=0.010) and the PBMC ARA to dihomo-gamma-linolenic acid (DGLA) ratio (P=0.035) were lower in the allergic children. Plasma 12-hydroxyeicosatetraenoic acid and 17-hydroxydocosahexaenoic acid (17-HDHA) were higher (P=0.040 and 0.020, respectively) in the allergic group. Thus, a fatty acid composition and lipid mediator levels indicative of increased release of ARA from PBMC membranes, increased inflammation as well as the resolving thereof, were associated with parent-reported allergy symptoms. This study used baseline data of an intervention study which was registered at clinicaltrials.gov as NCT01092377.

Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 8,11,14-Eicosatrienoic Acid; Anemia, Iron-Deficiency; Arachidonic Acid; Child; Cross-Sectional Studies; Docosahexaenoic Acids; Female; Humans; Hypersensitivity; Male; Rural Population; South Africa

2016