Page last updated: 2024-09-02

16-hydroxyestrone and Breast Neoplasms

16-hydroxyestrone has been researched along with Breast Neoplasms in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.33)18.7374
1990's15 (34.88)18.2507
2000's17 (39.53)29.6817
2010's9 (20.93)24.3611
2020's1 (2.33)2.80

Authors

AuthorsStudies
Brix, J; Gahler, RJ; Gerry, A; Glover, M; Green, T; Li, K; Newman, M; Reil, J; Schauch, M; See, J; Wood, S1
Altbach, M; Chalasani, P; Chow, HHS; Galons, JP; Huang, C; Maskarinec, G; Roe, DJ; Stopeck, A; Strom, MB; Thompson, PA; Thomson, CA; Wertheim, BC1
Boucher, BA; Chang, VC; Cotterchio, M; Jenkins, DJA; McCann, SE; Mirea, L; Thompson, LU1
Kurzer, MS; Samavat, H1
Huober, J; Mueck, AO; Ruan, X; Seeger, H; Wallwiener, D1
Godínez Martínez, EY; Juárez González, AR; Lemus Bravo, AE; Rodríguez Ventura, AL; Sámano, R; Santillán Ballesteros, R; Tolentino Dolores, M1
Fuhrman, BJ; Matthews, CE; Moore, SC; Ziegler, RG1
Gheldiu, AM; Loghin, F; Popa, DS; Vlase, L1
Byers, T; Lezotte, D; Risendal, B; Wacker, M; Westerlind, K1
Ahrendt, G; Garte, S; Im, A; Lloyd, S; Ragin, C; Taioli, E; Vogel, VG1
Bradlow, HL; Li, G; Sepkovic, DW; Telang, NT; Wong, GY1
Custer, L; Franke, AA; Heak, S; Maskarinec, G; Morimoto, Y1
Agostara, B; Amoroso, M; Bellavia, V; Carruba, G; Castagnetta, LA; Granata, OM; Miele, M; Ravazzolo, B; Traina, A1
Bradlow, HL; Cheng, JR; Fowke, JH; Gao, YT; Jin, F; Qi, D; Shu, XO; Zheng, W1
Bradlow, HL; Jernström, H; Klug, TL; Narod, SA; Sepkovic, DW1
Alvarez-Vasquez, RB; Axelrod, D; Bradlow, HL; Frenkel, K; Newman, MC; Sepkovic, DW; Zumoff, B1
Bauer, DC; Cauley, JA; Cummings, SR; Danielson, ME; Kuller, LH; Ljung, BM; Zmuda, JM1
Albanese, C; Gallo, MA; Lewis, JS; Pestell, RG; Thomas, T; Thomas, TJ1
Loft, S; Olsen, A; Overvad, K; Thomsen, BL; Tjonneland, A; Wellejus, A1
Bradlow, HL; Britton, JA; Gammon, MD; Kabat, GC; Neugut, AI; O'Leary, ES; Sepkovic, DW; Teitelbaum, SL; Terry, MB1
Kim, SH; Lee, SU; Min, YK; Rhee, Mc1
Bradlow, HL; Davis, DL; Lin, G; Sepkovic, D; Tiwari, R1
Gentzschein, E; London, S; Paganini-Hill, A; Pike, MC; Ross, RK; Stanczyk, FZ; Ursin, G2
Adlercreutz, H; Bradlow, HL; Donaldson, JL; Falk, RT; Fears, TR; Fillmore, CM; Gail, MH; Hoover, RN; Kiuru, P; Rossi, SC; Sepkovic, D; Siiteri, PK; Vaught, JB; Wahala, K; Ziegler, RG1
Bradlow, HL; Chang, CJ; Hu, XP; Kabat, GC; Khalil, A; Rosenblatt, R; Sepkovie, DW; Sparano, JA1
Foo, SC; Ho, GH; Ji, CY; Luo, XW; Ng, EH1
Allen, DS; Bradlow, HL; De Stavola, B; Fentiman, I; Kuller, LH; Meilahn, EN; Sepkovic, DW1
Gupta, M; McDougal, A; Safe, S1
Bradlow, HL; Ganguly, S; Garbers, SV; Garte, SJ; Osborne, MP; Sepkovic, DW; Taioli, E; Trachman, J1
Carruba, G; Castagnetta, LA1
Bradlow, HL; Guo, L; Mittelman, A; Singhal, H; Tiwari, RK1
Anderson, KE; Cree, M; Grady, JJ; Josyula, S; Lu, LJ; Nagamani, M1
Fowke, JH; Hebert, JR; Longcope, C1
Bradlow, HL; Jernström, H; Narod, SA; Vesprini, D1
Bradlow, HL; De Stavola, B; dos Santos Silva, I; Linos, A; Linos, D; Riza, E; Sepkovic, DW1
Gallo, MA; Klinge, CM; Lewis, JS; Thomas, T; Thomas, TJ1
Bernstein, L; Gentzschein, E; London, S; Pike, MC; Stanczyk, FZ; Tseng, CC; Ursin, G; Yang, D1
Imoto, S1
Fishman, J; Swaneck, GE2
Arts, CJ; de Bie, AT; van den Berg, H; Wilmer, JW1
Blankenstein, MA; Thijssen, JH1

Reviews

2 review(s) available for 16-hydroxyestrone and Breast Neoplasms

ArticleYear
Estrogen metabolism and breast cancer.
    Cancer letters, 2015, Jan-28, Volume: 356, Issue:2 Pt A

    Topics: Breast Neoplasms; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; Estradiol; Estrogens; Female; Humans; Hydroxyestrones; Postmenopause; Premenopause; Receptors, Estrogen; Risk; Risk Factors

2015
Epidemiologic studies of estrogen metabolism and breast cancer.
    Steroids, 2015, Volume: 99, Issue:Pt A

    Topics: Breast Neoplasms; Chromatography, Liquid; Epidemiologic Studies; Estrogens; Female; Humans; Hydroxyestrones; Postmenopause; Premenopause; Prospective Studies; Risk Factors; Tandem Mass Spectrometry

2015

Trials

6 trial(s) available for 16-hydroxyestrone and Breast Neoplasms

ArticleYear
A randomized, double-blind, placebo-controlled, cross-over trial to evaluate the effect of EstroSense
    Journal of complementary & integrative medicine, 2023, Mar-01, Volume: 20, Issue:1

    Topics: Biomarkers; Breast Neoplasms; Cross-Over Studies; Estrogens; Female; Humans; Hydroxyestrones

2023
A randomized, placebo-controlled trial of diindolylmethane for breast cancer biomarker modulation in patients taking tamoxifen.
    Breast cancer research and treatment, 2017, Volume: 165, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Double-Blind Method; Female; Humans; Hydroxyestrones; Indoles; Mammography; Middle Aged; Sex Hormone-Binding Globulin; Tamoxifen; Time Factors; Treatment Outcome

2017
Effect of Dietary Flaxseed Intake on Circulating Sex Hormone Levels among Postmenopausal Women: A Randomized Controlled Intervention Trial.
    Nutrition and cancer, 2019, Volume: 71, Issue:3

    Topics: Breast Neoplasms; Canada; Diet; Female; Flax; Gonadal Steroid Hormones; Humans; Hydroxyestrones; Lignans; Middle Aged; Postmenopause; Prolactin

2019
The relation of urinary estrogen metabolites with mammographic densities in premenopausal women.
    Cancer epidemiology, 2012, Volume: 36, Issue:5

    Topics: Adult; Asian People; Breast; Breast Neoplasms; Cell Count; Estrogens; Female; Humans; Hydroxyestrones; Mammography; Middle Aged; Premenopause; Progesterone; Risk Assessment; Testosterone

2012
Role of estradiol metabolism and CYP1A1 polymorphisms in breast cancer risk.
    Cancer detection and prevention, 1999, Volume: 23, Issue:3

    Topics: Adult; Black People; Breast Neoplasms; Case-Control Studies; Cytochrome P-450 CYP1A1; Estradiol; Estrogen Antagonists; Female; Gene Expression Regulation, Neoplastic; Genotype; Humans; Hydroxyestrones; Indoles; Male; Middle Aged; Polymorphism, Genetic; Risk Factors; RNA, Messenger; White People

1999
Brassica vegetable consumption shifts estrogen metabolism in healthy postmenopausal women.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2000, Volume: 9, Issue:8

    Topics: Aged; Analysis of Variance; Anticarcinogenic Agents; Brassica; Breast Neoplasms; Estrogens; Female; Humans; Hydroxyestrones; Least-Squares Analysis; Middle Aged; Phytotherapy; Postmenopause

2000

Other Studies

35 other study(ies) available for 16-hydroxyestrone and Breast Neoplasms

ArticleYear
The ratio of the estradiol metabolites 2-hydroxyestrone (2-OHE1) and 16α-hydroxyestrone (16-OHE1) may predict breast cancer risk in postmenopausal but not in premenopausal women: two case-control studies.
    Archives of gynecology and obstetrics, 2015, Volume: 291, Issue:5

    Topics: Adult; Biomarkers; Breast Neoplasms; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Estradiol; Estrogens; Female; Genetic Predisposition to Disease; Humans; Hydroxyestrones; Middle Aged; Postmenopause; Premenopause; Sensitivity and Specificity

2015
[Determination of 2-hydroxyestrone /16α-hydroxyestrone ratio in urine of Mexican women as a risk indicator for breast cancer and its relationship with other risk factors].
    Nutricion hospitalaria, 2014, Oct-25, Volume: 31, Issue:2

    Topics: Adolescent; Adult; Aged; Biomarkers, Tumor; Body Mass Index; Breast Neoplasms; Cross-Sectional Studies; Female; Humans; Hydroxyestrones; Male; Mexico; Middle Aged; Risk Factors; Young Adult

2014
Oxidative Metabolism of Estrone Modified by Genistein and Bisphenol A in Rat Liver Microsomes.
    Biomedical and environmental sciences : BES, 2015, Volume: 28, Issue:11

    Topics: Animals; Benzhydryl Compounds; Biomarkers; Breast Neoplasms; Drug Synergism; Endocrine Disruptors; Estrone; Genistein; Hydroxyestrones; Male; Microsomes, Liver; Oxidation-Reduction; Phenols; Rats, Wistar

2015
Ethnicity, body size, and estrogen levels in postmenopausal Hispanic and non-Hispanic white women.
    Journal of women's health (2002), 2009, Volume: 18, Issue:4

    Topics: Aged; Body Size; Breast Neoplasms; Cross-Sectional Studies; Female; Follow-Up Studies; Hispanic or Latino; Humans; Hydroxyestrones; Middle Aged; Postmenopause; Risk; White People

2009
Urinary estrogen metabolites in women at high risk for breast cancer.
    Carcinogenesis, 2009, Volume: 30, Issue:9

    Topics: Adult; Aged; Alcohol Drinking; Body Mass Index; Breast Neoplasms; Female; Humans; Hydroxyestrones; Linear Models; Middle Aged; Smoking

2009
Anti-proliferative effects of Chinese herb Cornus officinalis in a cell culture model for estrogen receptor-positive clinical breast cancer.
    Molecular medicine reports, 2012, Volume: 5, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Aggregation; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Cornus; Drugs, Chinese Herbal; Estradiol; Female; Fruit; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyestrones; Models, Biological; Plant Extracts; Receptors, Estrogen

2012
Tissue content of hydroxyestrogens in relation to survival of breast cancer patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:10

    Topics: Adult; Aged; Binding Sites; Breast Neoplasms; Chromatography, High Pressure Liquid; Estradiol; Estrogens; Estrogens, Catechol; Female; Follow-Up Studies; Humans; Hydroxyestrones; Immunoenzyme Techniques; Middle Aged; Receptors, Estrogen; Survival Rate

2002
Urinary estrogen metabolites and breast cancer: differential pattern of risk found with pre- versus post-treatment collection.
    Steroids, 2003, Volume: 68, Issue:1

    Topics: Adult; Breast Neoplasms; Case-Control Studies; China; Estrogens; Female; Humans; Hydroxyestrones; Middle Aged; Odds Ratio; Postmenopause; Premenopause; Risk Factors

2003
Predictors of the plasma ratio of 2-hydroxyestrone to 16alpha-hydroxyestrone among pre-menopausal, nulliparous women from four ethnic groups.
    Carcinogenesis, 2003, Volume: 24, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Black People; Breast Neoplasms; Contraceptive Agents; Estrogen Replacement Therapy; Ethnicity; Female; Humans; Hydroxyestrones; Menstrual Cycle; Parity; Premenopause; Risk Factors; White People

2003
Influence of postmenopausal hormone replacement therapy on an estrogen metabolite biomarker of risk for breast cancer.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2003, Volume: 35, Issue:6

    Topics: Biomarkers, Tumor; Breast Neoplasms; Cross-Sectional Studies; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Humans; Hydroxyestrones; Medroxyprogesterone Acetate; Postmenopause; Risk Factors

2003
Estrogen metabolites and the risk of breast cancer in older women.
    Epidemiology (Cambridge, Mass.), 2003, Volume: 14, Issue:6

    Topics: Aged; Breast Neoplasms; Case-Control Studies; Cohort Studies; Estrogens; Female; Humans; Hydroxyestrones; Risk Factors; Steroid 16-alpha-Hydroxylase; Surveys and Questionnaires

2003
Differential effects of 16alpha-hydroxyestrone and 2-methoxyestradiol on cyclin D1 involving the transcription factor ATF-2 in MCF-7 breast cancer cells.
    Journal of molecular endocrinology, 2005, Volume: 34, Issue:1

    Topics: 2-Methoxyestradiol; Activating Transcription Factor 2; Blotting, Western; Breast Neoplasms; Cyclic AMP Response Element-Binding Protein; Cyclin D1; DNA Replication; Enzyme Activation; Estradiol; Female; Gene Expression Regulation, Neoplastic; Humans; Hydroxyestrones; p38 Mitogen-Activated Protein Kinases; Transcription Factors

2005
Urinary hydroxyestrogens and breast cancer risk among postmenopausal women: a prospective study.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2005, Volume: 14, Issue:9

    Topics: Biomarkers; Breast Neoplasms; Case-Control Studies; Estriol; Female; Hormone Replacement Therapy; Humans; Hydroxyestrones; Middle Aged; Postmenopause; Receptors, Estrogen

2005
Estrogen metabolism and breast cancer.
    Epidemiology (Cambridge, Mass.), 2006, Volume: 17, Issue:1

    Topics: Aged; Breast Neoplasms; Case-Control Studies; Estrogens; Female; Humans; Hydroxyestrones; Immunoenzyme Techniques; Middle Aged; New York; Surveys and Questionnaires

2006
Involvement of peroxiredoxin IV in the 16alpha-hydroxyestrone-induced proliferation of human MCF-7 breast cancer cells.
    Cell biology international, 2008, Volume: 32, Issue:4

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Hydroxyestrones; Peroxiredoxins; Protein Isoforms

2008
Effects of pesticides on the ratio of 16 alpha/2-hydroxyestrone: a biologic marker of breast cancer risk.
    Environmental health perspectives, 1995, Volume: 103 Suppl 7

    Topics: Biomarkers; Breast Neoplasms; Estradiol; Estrogens, Catechol; Humans; Hydroxyestrones; Insecticides; Tumor Cells, Cultured

1995
A pilot study of urinary estrogen metabolites (16alpha-OHE1 and 2-OHE1) in postmenopausal women with and without breast cancer.
    Environmental health perspectives, 1997, Volume: 105 Suppl 3

    Topics: Breast Neoplasms; Case-Control Studies; Estradiol; Estriol; Estrone; Female; Humans; Hydroxyestrones; Menopause; Middle Aged; Neoplasms, Hormone-Dependent; Pilot Projects; Risk Factors; Steroid 16-alpha-Hydroxylase

1997
Quantifying estrogen metabolism: an evaluation of the reproducibility and validity of enzyme immunoassays for 2-hydroxyestrone and 16alpha-hydroxyestrone in urine.
    Environmental health perspectives, 1997, Volume: 105 Suppl 3

    Topics: Adult; Biomarkers; Breast Neoplasms; Estrogens; Evaluation Studies as Topic; Female; Follicular Phase; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyestrones; Immunoenzyme Techniques; Luteal Phase; Menopause; Middle Aged; Neoplasms, Hormone-Dependent; Reproducibility of Results; Risk Factors

1997
Urinary estrogen metabolites and breast cancer: a case-control study.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1997, Volume: 6, Issue:7

    Topics: Adult; Aged; Biomarkers, Tumor; Breast Neoplasms; Case-Control Studies; Estrogens; Female; Humans; Hydroxyestrones; Middle Aged; New York; Postmenopause; Risk

1997
Urinary 2/16 alpha-hydroxyestrone ratio: correlation with serum insulin-like growth factor binding protein-3 and a potential biomarker of breast cancer risk.
    Annals of the Academy of Medicine, Singapore, 1998, Volume: 27, Issue:2

    Topics: Age Factors; Anticarcinogenic Agents; Biomarkers, Tumor; Body Mass Index; Breast Neoplasms; Cell Transformation, Neoplastic; Confidence Intervals; Contraceptives, Oral; Disease Progression; Estradiol; Estrogens, Catechol; Female; Forecasting; Humans; Hydroxyestrones; Hydroxylation; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Linear Models; Logistic Models; Menopause; Middle Aged; Odds Ratio; Parity; Risk Factors

1998
Do urinary oestrogen metabolites predict breast cancer? Guernsey III cohort follow-up.
    British journal of cancer, 1998, Volume: 78, Issue:9

    Topics: Adult; Breast Neoplasms; Cohort Studies; Female; Follow-Up Studies; Humans; Hydroxyestrones; Incidence; Predictive Value of Tests; Prospective Studies; Risk Factors

1998
Estrogenic and antiestrogenic activities of 16alpha- and 2-hydroxy metabolites of 17beta-estradiol in MCF-7 and T47D human breast cancer cells.
    The Journal of steroid biochemistry and molecular biology, 1998, Volume: 67, Issue:5-6

    Topics: Breast Neoplasms; Cathepsin D; Cell Division; Creatine Kinase; Estradiol; Estriol; Female; Humans; Hydroxyestrones; Isoenzymes; Promoter Regions, Genetic; Receptors, Estrogen; Recombinant Proteins; Transfection; Tumor Cells, Cultured

1998
Urinary 2-hydroxyestrone/16alpha-hydroxyestrone ratio and risk of breast cancer in postmenopausal women.
    Journal of the National Cancer Institute, 1999, Jun-16, Volume: 91, Issue:12

    Topics: Aged; Breast Neoplasms; Case-Control Studies; Female; Humans; Hydroxyestrones; Immunoenzyme Techniques; Middle Aged; Odds Ratio; Postmenopause; Radioimmunoassay; Risk; Risk Factors; Steroid 16-alpha-Hydroxylase

1999
Re: Urinary 2-hydroxyestrone/16alpha-hydroxyestrone ratio and risk of breast cancer in postmenopausal women.
    Journal of the National Cancer Institute, 1999, Nov-03, Volume: 91, Issue:21

    Topics: Adult; Breast Neoplasms; Female; Humans; Hydroxyestrones; Middle Aged; Postmenopause; Research Design; Risk; Risk Factors

1999
Endocrine characteristics of human breast epithelial cells, MCF-10F.
    Hormone research, 1999, Volume: 52, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aromatase; Aryl Hydrocarbon Hydroxylases; Breast; Breast Neoplasms; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Epithelial Cells; Estradiol; Estriol; Female; Humans; Hydroxyestrones; Steroid 16-alpha-Hydroxylase; Tumor Cells, Cultured

1999
Increased urinary excretion of 2-hydroxyestrone but not 16alpha-hydroxyestrone in premenopausal women during a soya diet containing isoflavones.
    Cancer research, 2000, Mar-01, Volume: 60, Issue:5

    Topics: Adult; Breast Neoplasms; Diet; Female; Glycine max; Humans; Hydroxyestrones; Isoflavones; Neoplasms, Hormone-Dependent; Premenopause

2000
Re: CYP17 promoter polymorphism and breast cancer in Australian women under age forty years.
    Journal of the National Cancer Institute, 2001, Apr-04, Volume: 93, Issue:7

    Topics: Adolescent; Adult; Asian People; Australia; Black People; Breast Neoplasms; Female; Genotype; Humans; Hydroxyestrones; Native Hawaiian or Other Pacific Islander; Polymorphism, Genetic; Promoter Regions, Genetic; Steroid 17-alpha-Hydroxylase; White People

2001
Urinary estrogen metabolites and mammographic parenchymal patterns in postmenopausal women.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2001, Volume: 10, Issue:6

    Topics: Adult; Aged; Breast Neoplasms; Case-Control Studies; Epidemiologic Studies; Estrogens; Female; Humans; Hydroxyestrones; Mammography; Middle Aged; Postmenopause; Risk Factors; Steroid 16-alpha-Hydroxylase

2001
Regulation of cell cycle and cyclins by 16alpha-hydroxyestrone in MCF-7 breast cancer cells.
    Journal of molecular endocrinology, 2001, Volume: 27, Issue:3

    Topics: Breast Neoplasms; CDC2-CDC28 Kinases; Cell Cycle; Cell Division; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; Cyclins; DNA, Neoplasm; Estradiol; Female; Genes, Reporter; Humans; Hydroxyestrones; Luciferases; Neoplasms, Hormone-Dependent; Phosphorylation; Protein Serine-Threonine Kinases; Receptors, Estrogen; Retinoblastoma Protein; RNA, Messenger; Transcriptional Activation; Tumor Cells, Cultured

2001
Urinary 2-hydroxyestrone/16alpha-hydroxyestrone ratio and family history of breast cancer in premenopausal women.
    Breast cancer research and treatment, 2002, Volume: 72, Issue:2

    Topics: Adult; Biomarkers; Breast Neoplasms; Estradiol; Estriol; Estrogens; Estrone; Female; Genetic Predisposition to Disease; Humans; Hydroxyestrones; Middle Aged; Premenopause

2002
[Biological effect of estrogen metabolites in human breast cancer].
    Nihon Geka Gakkai zasshi, 1992, Volume: 93, Issue:5

    Topics: Adolescent; Adult; Aged; Aryl Hydrocarbon Hydroxylases; Breast Neoplasms; Cell Division; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Estrogens; Female; Humans; Hydroxyestrones; Middle Aged; Receptors, Estrogen; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Tumor Cells, Cultured

1992
Effects of estrogens on MCF-7 cells: positive or negative regulation by the nature of the ligand-receptor complex.
    Biochemical and biophysical research communications, 1991, Jan-15, Volume: 174, Issue:1

    Topics: Breast Neoplasms; Cell Count; Estradiol; Estrogens; Female; Humans; Hydroxyestrones; Ligands; Receptors, Estrogen; Receptors, Progesterone; Tumor Cells, Cultured

1991
In vitro synthesis of 16 alpha-hydroxyestrone by female rat liver microsomes: its possible role in the etiology of breast cancer.
    Journal of steroid biochemistry, 1990, Aug-28, Volume: 36, Issue:6

    Topics: Animals; Breast Neoplasms; Chromatography, High Pressure Liquid; Estrone; Female; Hydroxyestrones; In Vitro Techniques; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Microsomes, Liver; Mutagenicity Tests; Rats; Rats, Inbred Strains

1990
Uptake and metabolism of estradiol by normal and abnormal breast tissues.
    Annals of the New York Academy of Sciences, 1990, Volume: 586

    Topics: Adult; Breast; Breast Neoplasms; Estradiol; Estriol; Estrone; Female; Fibrocystic Breast Disease; Humans; Hydroxyestrones

1990
Covalent binding of the endogenous estrogen 16 alpha-hydroxyestrone to estradiol receptor in human breast cancer cells: characterization and intranuclear localization.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:21

    Topics: Antibodies, Monoclonal; Breast Neoplasms; Cell Division; Cell Line; Cell Nucleus; Electrophoresis, Polyacrylamide Gel; Estradiol; Estrone; Humans; Hydroxyestrones; Receptors, Estradiol; Steroid 16-alpha-Hydroxylase

1988